LOCUS       NM_001193628            2543 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens small integral membrane protein 17 (SMIM17), mRNA.
ACCESSION   NM_001193628 XM_001718473 XM_001718506 XM_001719187
VERSION     NM_001193628.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2543)
  AUTHORS   Ota,T., Suzuki,Y., Nishikawa,T., Otsuki,T., Sugiyama,T., Irie,R.,
            Wakamatsu,A., Hayashi,K., Sato,H., Nagai,K., Kimura,K., Makita,H.,
            Sekine,M., Obayashi,M., Nishi,T., Shibahara,T., Tanaka,T.,
            Ishii,S., Yamamoto,J., Saito,K., Kawai,Y., Isono,Y., Nakamura,Y.,
            Nagahari,K., Murakami,K., Yasuda,T., Iwayanagi,T., Wagatsuma,M.,
            Shiratori,A., Sudo,H., Hosoiri,T., Kaku,Y., Kodaira,H., Kondo,H.,
            Sugawara,M., Takahashi,M., Kanda,K., Yokoi,T., Furuya,T.,
            Kikkawa,E., Omura,Y., Abe,K., Kamihara,K., Katsuta,N., Sato,K.,
            Tanikawa,M., Yamazaki,M., Ninomiya,K., Ishibashi,T., Yamashita,H.,
            Murakawa,K., Fujimori,K., Tanai,H., Kimata,M., Watanabe,M.,
            Hiraoka,S., Chiba,Y., Ishida,S., Ono,Y., Takiguchi,S., Watanabe,S.,
            Yosida,M., Hotuta,T., Kusano,J., Kanehori,K., Takahashi-Fujii,A.,
            Hara,H., Tanase,T.O., Nomura,Y., Togiya,S., Komai,F., Hara,R.,
            Takeuchi,K., Arita,M., Imose,N., Musashino,K., Yuuki,H., Oshima,A.,
            Sasaki,N., Aotsuka,S., Yoshikawa,Y., Matsunawa,H., Ichihara,T.,
            Shiohata,N., Sano,S., Moriya,S., Momiyama,H., Satoh,N., Takami,S.,
            Terashima,Y., Suzuki,O., Nakagawa,S., Senoh,A., Mizoguchi,H.,
            Goto,Y., Shimizu,F., Wakebe,H., Hishigaki,H., Watanabe,T.,
            Sugiyama,A., Takemoto,M., Kawakami,B., Yamazaki,M., Watanabe,K.,
            Kumagai,A., Itakura,S., Fukuzumi,Y., Fujimori,Y., Komiyama,M.,
            Tashiro,H., Tanigami,A., Fujiwara,T., Ono,T., Yamada,K., Fujii,Y.,
            Ozaki,K., Hirao,M., Ohmori,Y., Kawabata,A., Hikiji,T., Kobatake,N.,
            Inagaki,H., Ikema,Y., Okamoto,S., Okitani,R., Kawakami,T.,
            Noguchi,S., Itoh,T., Shigeta,K., Senba,T., Matsumura,K.,
            Nakajima,Y., Mizuno,T., Morinaga,M., Sasaki,M., Togashi,T.,
            Oyama,M., Hata,H., Watanabe,M., Komatsu,T., Mizushima-Sugano,J.,
            Satoh,T., Shirai,Y., Takahashi,Y., Nakagawa,K., Okumura,K.,
            Nagase,T., Nomura,N., Kikuchi,H., Masuho,Y., Yamashita,R.,
            Nakai,K., Yada,T., Nakamura,Y., Ohara,O., Isogai,T. and Sugano,S.
  TITLE     Complete sequencing and characterization of 21,243 full-length
            human cDNAs
  JOURNAL   Nat Genet 36 (1), 40-45 (2004)
   PUBMED   14702039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007228.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001193628.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.87376.1,
                                           SRR1660807.125848.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2154665
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000598409.6/ ENSP00000471126.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AC007228.1         96032-96083
            53-321              AC007228.1         98441-98709
            322-398             AC007228.1         100431-100507
            399-2543            AC007228.1         107976-110120
FEATURES             Location/Qualifiers
     source          1..2543
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.43"
     gene            1..2543
                     /gene="SMIM17"
                     /note="small integral membrane protein 17"
                     /db_xref="GeneID:147670"
                     /db_xref="HGNC:HGNC:27114"
     exon            1..52
                     /gene="SMIM17"
                     /inference="alignment:Splign:2.1.0"
     exon            53..321
                     /gene="SMIM17"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..509
                     /gene="SMIM17"
                     /codon_start=1
                     /product="small integral membrane protein 17"
                     /protein_id="NP_001180557.1"
                     /db_xref="CCDS:CCDS58683.1"
                     /db_xref="GeneID:147670"
                     /db_xref="HGNC:HGNC:27114"
                     /translation="MQSLRPEQTRGLLEPERTKTLLPRESRAWEKPPHPACTKDWEAV
                     EVGASSHDSDEKDLSSQETGLSQEWSSVEEDDESEGSQGFVEWSKAPQQTTIVLVVCV
                     LFLFLVLTGMPMMFHI"
     exon            322..398
                     /gene="SMIM17"
                     /inference="alignment:Splign:2.1.0"
     exon            399..2543
                     /gene="SMIM17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2521..2526
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM17"
                     /note="hexamer: AATAAA"
     polyA_site      2543
                     /gene="SMIM17"
                     /note="major polyA site"
ORIGIN      
        1 agtcagtgcg gcgccagctc tgcagagccc agacagggtc cggttgggga ggtcctcagg
       61 ttctgaatct tgtgcctgga gaaccagaga ggaccctgga gcaggaggag aaagagaagc
      121 ttgtctcaga agctccacct cctcctgggg caatgcagag tctcaggcct gagcagacac
      181 gggggctgct ggagcctgag aggaccaaga ctctgctgcc tcgggagagc cgggcctggg
      241 agaagcctcc tcatcccgcc tgcaccaaag actgggaggc tgtggaggtt ggggcctcca
      301 gccatgacag tgatgagaaa gacctgtctt ctcaagagac tgggctttcc caggagtgga
      361 gctcggtgga ggaagatgac gaatcagagg gctcccaggg ctttgtggag tggtcaaaag
      421 ctccacaaca aacaaccata gtcttggtag tgtgcgtgct ttttttgttc ctggttttaa
      481 cggggatgcc tatgatgttt cacatttaac tataatggtg gctgttgttt taaaagttta
      541 atttaatgaa atagatgccc tatgtcatgt taaggaattg tgctagttaa aaatcaggaa
      601 taggtgttga atattttcaa atgcctttca aacatccttt gagatgattt ttaaaaaatt
      661 tttggtgtga gttttcacat actttatttc catgaaatga agacatcatt gattgtaaaa
      721 cattattttg tataccacgg agaaagaaaa gtgctaatta atcattaaga tgccaccaac
      781 tggaagatat ctcctgactt tgagaagatg aaaaaatgtg caactgaaga tcaatgaaat
      841 ctggtacatt tcctaacatc aaaccaactt tgcattctta aggttttggt gcaccagtct
      901 tttcatacac tagattatat ttattgatat tttatgtagg attcttgcct ctatcttcac
      961 atgtgagatt ggtgctatct ttgtgaagtt ttggtatcat ggttaagctt gcatcataga
     1021 aagacttggg taacttttac cttttctatg cttttcaata gtttctgtag cttaggaagt
     1081 atcagtccct tgacacctta catgaattca ttgttataac caggtcatag agtcatggag
     1141 agaacgtttc agctaattct tgggcagctt tcttagttct ttacaatgtt atcagtttat
     1201 taatactttt tacctcttgc atttattttg gcgaattaca gaggtttttg tttttttttt
     1261 tttttgagac cgagtctcac tctgtcaccc agtctggagt gcagtggcgc catctcggct
     1321 cactgtaagc agagggttca tgccattctc ctgcctcagc ctcccaagta gctgggacta
     1381 caggcgccca ccaccatgcc cagctaattt tttgtatttt tagtagagac ggggtttcac
     1441 cgtgttagcc aggatggtct cgatctcctg acctcgtgat ccgcccgcct tggcctccca
     1501 aagtgctggg attacagatg tgagccaccg tgcccagccc agagttcttt tatcctctag
     1561 aaaattcttc attccataga gctttttcat attattagct taattatgca taatgtttta
     1621 taattaaaaa tttctcttta ttttgttcta tcccctgttt cctgtaaact gctgtttgtg
     1681 gtttactcgt tattagattt gtcaaaggtt tatctagctt actattgttt ttccaaagaa
     1741 ccaacattag gattcattta tatccattat ttcttttatt tgtaatttgt ttttctttga
     1801 tatgtattgc atttattttt tattgttttt cttctttgtc tcagttttta tactgaatac
     1861 ttgatttata ttctctttat attttctata atagcatact tattaacgca aatgtacttc
     1921 tggatatagc gttggccaca tcttaacatt tgattattca tttttgttta tgttgtctaa
     1981 aaattacatt gtagtgtgtc taaatattac attgtagtgt ttctaaagag tgctttgaaa
     2041 ctcagtgatt tggtttattt tttgtttaaa aatagttttg ttttcttgtt ttactgcact
     2101 gtgaacacag aatgtggcct ataacacatc tgcttccaaa actttttaaa aagcttttag
     2161 tgtggcctag aacatgtcca ttttttgtaa ttgtttcacg aacatttaag atgaagatat
     2221 cttctctgtc tgtagaactg aaaactttat gtgcctgtta gttaactcag tatcgtcaat
     2281 tatattgttc agattcatgt gttatctaat tttggcctat tatattcatt aaaaaccaat
     2341 aaggttatgt gaaactttgt tagtacaatt gtttttgcta ataaattttt ataatctttg
     2401 ctttatgtac tcaacagctg tgtaattcga ggcatataag tgcagcattg ttatgtcctt
     2461 gttaattaaa taatatatgt aaaacaccat atgacaatgg ctggcagata gtaggcactc
     2521 aataaatgtt aattaaaacc tga
//
