LOCUS       NM_001135575            4887 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens small integral membrane protein 13 (SMIM13), mRNA.
ACCESSION   NM_001135575 XM_001720414 XM_001724989 XM_001725361
VERSION     NM_001135575.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4887)
  AUTHORS   Cai,D.C., Fonteijn,H., Guadalupe,T., Zwiers,M., Wittfeld,K.,
            Teumer,A., Hoogman,M., Arias-Vasquez,A., Yang,Y., Buitelaar,J.,
            Fernandez,G., Brunner,H.G., van Bokhoven,H., Franke,B.,
            Hegenscheid,K., Homuth,G., Fisher,S.E., Grabe,H.J., Francks,C. and
            Hagoort,P.
  TITLE     A genome-wide search for quantitative trait loci affecting the
            cortical surface area and thickness of Heschl's gyrus
  JOURNAL   Genes Brain Behav 13 (7), 675-685 (2014)
   PUBMED   25130324
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136139.6, BC032356.1 and AA724884.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001135575.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.170665.1,
                                           SRR1803616.132444.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000416247.4/ ENSP00000451866.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               AL136139.6         11496-11694
            200-1965            BC032356.1         1-1766
            1966-4535           AL136139.6         53474-56043
            4536-4887           AA724884.1         23-374              c
FEATURES             Location/Qualifiers
     source          1..4887
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p24.2"
     gene            1..4887
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="small integral membrane protein 13"
                     /db_xref="GeneID:221710"
                     /db_xref="HGNC:HGNC:27356"
     exon            1..556
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /inference="alignment:Splign:2.1.0"
     CDS             481..756
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="UPF0766 protein C6orf228"
                     /codon_start=1
                     /product="small integral membrane protein 13"
                     /protein_id="NP_001129047.1"
                     /db_xref="CCDS:CCDS56396.1"
                     /db_xref="GeneID:221710"
                     /db_xref="HGNC:HGNC:27356"
                     /translation="MWHSVGLTLLVFVATLLIVLLLMVCGWYFVWHLFLSKFKFLREL
                     VGDTGSQEGDHEPSGSETEEDTSSSPHRIRSARQRRAPADEGHRPLT"
     exon            557..4887
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /inference="alignment:Splign:2.1.0"
     regulatory      900..905
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="hexamer: AATAAA"
     polyA_site      921
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="major polyA site"
     regulatory      4867..4872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="hexamer: AATAAA"
     polyA_site      4887
                     /gene="SMIM13"
                     /gene_synonym="C6orf228"
                     /note="major polyA site"
ORIGIN      
        1 ggagaagccg ctacagccgc ggccgggcga cgctgacatc tggcatccct ggggtctcag
       61 agacacgggt ggacagcgac gagggccttg tggccgccgt gtgtacccgt gcttaccctc
      121 tgtcctccct acaggcgcgc ggcgtccgcc atggaagcgc atccgaccgc tggggtctct
      181 gggtgccgcg gcctcggctc tccggggcga tgagggacta gaggcgccct gaggcccgcc
      241 tgcctcccgc gctctggcca ccccggcggg aaaaggatcg ggcgggcggg cggtcccaca
      301 gtgcccgcct ttgcgccgcc ccaccccctg ggggcgctgc cgagggggcg ccagccgccc
      361 atgccgcccc ggcgcccagc cgcgcctggc gcccgccgct gaagcgcagg acgcgccgcc
      421 gcccgcgctc accgccgtcc gcgccagccg ccccgagccg actgcccttc tgcccccaag
      481 atgtggcaca gcgtcgggct gactctgctt gtgttcgtgg ccacgctgct gatcgtcctg
      541 ctgctgatgg tgtgcggttg gtattttgta tggcatcttt ttttatcaaa attcaagttt
      601 ctccgggaac tggtgggaga cacaggatcc caagagggag atcatgagcc ttcagggtct
      661 gaaactgaag aagacacttc ctcctctcca cacagaatca gatccgctcg ccaaaggagg
      721 gcacctgctg atgaaggcca cagacccctg acatagtcct gtacttgtga aggatgaaaa
      781 ggcagttgcc agcttctgtc ttttactgac ttcgctttga aatttactaa tgactgaaga
      841 acatttgtat tggattttaa gtcgaatttt aaaaaagatt tacatgtaag ccatataaaa
      901 ataaagggaa ctgaaaccaa attggactat tataaatttc atcttaaaga taatcttttg
      961 tttcaccagc tttctactta tacacttatt ccttggcttt tgggcttatt ttcttgcact
     1021 ggtgcagatc tggtaaacat taaaggcttg aaaaaccata ttttgttagc cctaaaatgt
     1081 acatttttct tcccatttta acttatctga aattgggatg catctcatta ctgtcaacca
     1141 ggtgatagtc atgtaacgct cctaccgtgt gcatgtgtga atttacagct tgtcatcgtg
     1201 tcatcccttt aaccaacatg tgttttgttg gtatcaaatg tgtcaggttt aattgacatt
     1261 ttaaaatgtc ttcaaaaaga tcacactatg attcagcatt gaaacgaaaa gttattgtgt
     1321 atgcagaaaa gcatggaaac agagcagcag ggcgtacatt tgatattagt gaagcaaata
     1381 ttcgtcgctg gagaaatgat cgcaattcca tattttcctg caaagcaaca acaaaatgtt
     1441 ttacgggacc taagaaaggt aggtacccac aagtagatga agctgtacta cgtttcgtca
     1501 gtgagacacg tgcaaaagga ttgcctatca cacgccaagc aatgcaattg aaggcaggag
     1561 aagttgccaa aaccctagga attgatgaaa caaaattcaa agccacaaga ggctggtgtg
     1621 accgattcat gcgtcgagca ggactatcat taaggcatca aacatcgttt tgtcccaagc
     1681 tccccactgc cattaaacag aagacagtgt tggagcactc tttcaagaag tgctgcataa
     1741 ccagtactct tgacaacacc gggagagacg ttctgtggaa aaatgcagac atcaatgact
     1801 gtggtttgaa aagtgattca gaagagttgg attcagaata tgaagttata attataactt
     1861 aaccaattta tttcacacat tttctttaca tatgcacaag attgatgtga taaaaatctg
     1921 tttaactcaa agcgctgttt caataaatat aaacattttc tgtgatatga aagcattgtg
     1981 tcatagttta atgggcagtg ttttttctta gtgatacata tggtgcatct taacaattgg
     2041 tagtgtctta ggttaaatta aaaatggtag cttgtaaatt tatttttctt tttaagatag
     2101 cagttattta ttggggaatt tgattctgac tcttacaatg ttaaacttgt aatcctgtgt
     2161 gaaacacatg tttttggggg ggagggggta accaagattt cagggtagta acttaggaat
     2221 ctaagaacta tcttctactt taggaagagt gggattagtt actccctttg tataggagga
     2281 ctttatgctc aaggaatgtg ttgtggagaa aaacacttct tcacaaacaa ttcagtgaca
     2341 agacctcaaa ggtaatgcgt attgaggaaa acagtagtgg gtgaaaattc ccgcttagct
     2401 gtaaaatgac tctcttgcca ggtttccgtg tttgtctcaa ctgaactctg ggctgagtgt
     2461 ttaccaggga gaagagatgt gaattaaaca accttcctgt ttagtgttac ctgctttgta
     2521 caagaatgaa gtgcaaagcc aacttacttt attaatccaa gttcttttta tgtttttctt
     2581 aacctttatt aaggactagt catcacaaaa tatctattta acctctattt tatgatggtg
     2641 tgttattatg tttgatacct catacttctt gcttagagtt ttgtttaaca gttcactggc
     2701 tctgtcccaa tgtttgtgat gaacaccttt ttgctatatt gtagctcttg gagatactaa
     2761 aagagaattc acagaacata actttagttt tatgtgtttg ctaggggaag atttcctagc
     2821 agctgagagc aaggcacagt ctctgtcttc atttctttat tagatacaat tttctatttt
     2881 tatgtgactc tagggcataa caaaacagtg acagtttcaa gcgttaattt taatgcttcc
     2941 tactagctaa atatcatctt aaaatgatta tcagaaaaaa aaataatgcc cccaaaaact
     3001 tttgggggca ttatttggta ctgggaggat atttaaatta gatttttcat agtctattgt
     3061 tttgaactat ggattctgtt ttatggtgga tacctaaggt ttatataata gttgctggaa
     3121 aacttaaagt agctggtgag cttcctgtta tgtcactatt aaagaatgat ggctgatgta
     3181 actctgcccc tgaaatctac aagggtcatg cccaaattaa tacaggttaa cctttgtaga
     3241 ggtatatatg ttggcattat ttattgacat ttatgcttca agcatgtctt attttatgta
     3301 attttaagaa atactctatt taacttgtga aatataccta aaagcatact agttagctct
     3361 tagactctca cttagggagg gtaaagaaac atcactgatg ccaatatgaa gatctataaa
     3421 caaatccttt gtttagaact tttttctctt cgtgcacctc acaacacact taccatggta
     3481 catatttctt aatgccacta agaaaggcaa gatagtgaac gcagaattat ttatgtggta
     3541 tagtgtttgt tttcctgttt tagtgctttt gtagctaaaa cttactggaa ctgcatcaca
     3601 actacatttg cagtctcagt gggaggtgga ctagcctgtg gttaatttta gagcttaaaa
     3661 gtttataagc attaaaaaca catacatgta ttagaatctt gtctaacccc tcacaaagga
     3721 tgatggtgat cagcatgcca tcttttgaag attaattcta aaattgagga ctctggtagg
     3781 ttgttttatt tccttcccaa ccagccattc atttccaatt gttctgcctt tgaaactttt
     3841 tgtgaaaatt gcctgtacca attgcattgg ttgcgttgct ctgatttaaa tgccaaaaac
     3901 actaaatatt tgtgtagtgc tgttaaatga ggtttttgat atttccatca aaatgaatat
     3961 aaaattcact tgatggattt tgtagtgatg ttttcacagt tgaaacaaac atattgctgt
     4021 gcggtggaca gccacttcac agacatgcag acccatttct ttagagatat taggtttaaa
     4081 acccatttta attttatttt gctgaaggtt tggaatatat aaagtaatgg attcacaaaa
     4141 tatgatatct taaaacatgt tgaaagattt gaaagtggtg catttttact tttaagagca
     4201 gcaatctttg aaattagtca acaatgcagt cttttttaaa agtcagtttt ctcaagtagt
     4261 atgttgtaac gtaagatgta actgatataa ctagattttg actggtaaac ttaaagtgct
     4321 ttttatattt gaggttgact ttaaaaagcc attgagcagt cctcagaggt tatggactct
     4381 caagcgacta atggaatagt gttctgttgt gaagtctaga actaaagcac cttgtattgt
     4441 ctgcttctaa agtgtcctat agtttttaac ttaaagtgta aagagtaaca ttttatctta
     4501 tgtcaattaa agttacattt ttcatttgtt ggtgtacatg tgctacctgt tttatgggga
     4561 atgtttaaca cgatcctcca agttggttct atgcataacc attcaccaaa tactgctgct
     4621 gtgattcctt gaaggaaata ttctgtggtc tgctatgatg cattgccatc ttgctgcttg
     4681 acaataggtt tataaataat tagaattacg tgttttaata gtacctttgt atatataaca
     4741 agatgtaaaa ttaaagatga ggaatgtgtg taaatgatca ttcactgttt ttgttttaaa
     4801 actggtcagt actatgaagc ttctgtggtt tgtatgatgt tttaactttc actttaaact
     4861 gcatagaata aattaaattg aaaacaa
//
