LOCUS       NM_001271592            4823 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens small integral membrane protein 10 like 1 (SMIM10L1),
            mRNA.
ACCESSION   NM_001271592
VERSION     NM_001271592.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4823)
  AUTHORS   Nebe,M., Kehr,S., Schmitz,S., Breitfeld,J., Lorenz,J., Le Duc,D.,
            Stadler,P.F., Meiler,J., Kiess,W., Garten,A. and Kirstein,A.S.
  TITLE     Small integral membrane protein 10 like 1 downregulation enhances
            differentiation of adipose progenitor cells
  JOURNAL   Biochem Biophys Res Commun 604, 57-62 (2022)
   PUBMED   35290761
  REMARK    GeneRIF: Small integral membrane protein 10 like 1 downregulation
            enhances differentiation of adipose progenitor cells.
REFERENCE   2  (bases 1 to 4823)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (bases 1 to 4823)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134349.2.
            
            On May 17, 2019 this sequence version replaced NM_001271592.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1803614.77135.1, SRR1803614.228632.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000622602.2/ ENSP00000488907.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4823              AC134349.2         1602-6424           c
FEATURES             Location/Qualifiers
     source          1..4823
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.2"
     gene            1..4823
                     /gene="SMIM10L1"
                     /note="small integral membrane protein 10 like 1"
                     /db_xref="GeneID:100129361"
                     /db_xref="HGNC:HGNC:49847"
     exon            1..4823
                     /gene="SMIM10L1"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..370
                     /gene="SMIM10L1"
                     /note="chromosome X open reading frame 69-like"
                     /codon_start=1
                     /product="small integral membrane protein 10-like protein
                     1"
                     /protein_id="NP_001258521.1"
                     /db_xref="CCDS:CCDS81667.1"
                     /db_xref="GeneID:100129361"
                     /db_xref="HGNC:HGNC:49847"
                     /translation="MAPAAAPSSLAVRASSPAATPTSYGVFCKGLSRTLLAFFELAWQ
                     LRMNFPYFYVAGSVILNIRLQVHI"
     regulatory      1064..1069
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM10L1"
                     /note="hexamer: AATAAT"
     polyA_site      1078
                     /gene="SMIM10L1"
                     /note="major polyA site"
     polyA_site      1082
                     /gene="SMIM10L1"
                     /note="major polyA site"
     regulatory      1798..1803
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM10L1"
                     /note="hexamer: ATTAAA"
     polyA_site      1821
                     /gene="SMIM10L1"
     regulatory      1913..1918
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM10L1"
                     /note="hexamer: AATAAA"
     polyA_site      1944
                     /gene="SMIM10L1"
     polyA_site      2034
                     /gene="SMIM10L1"
     regulatory      3215..3220
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM10L1"
                     /note="hexamer: AATAAA"
     polyA_site      3245
                     /gene="SMIM10L1"
     regulatory      4799..4804
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMIM10L1"
                     /note="hexamer: AATAAA"
     polyA_site      4823
                     /gene="SMIM10L1"
ORIGIN      
        1 ggctacgcgc cgcactgcac cgagcggcgg cagcggcaag cttgggtgtg agcccgggag
       61 ccgctttgct taccgtcctg ccggtcccag ccgtcgctag gaggtccgcg ggccctgcgg
      121 caaccctcgc tacagacgct gggcgggcgg cgacacctgg ctcatggccc ccgcggcggc
      181 tccgtcctcc ttggccgtca gggcctcaag ccccgccgcg acacccacct cgtacggcgt
      241 cttctgcaag gggctctccc gcaccctgct cgccttcttc gagctggcct ggcagctgcg
      301 catgaacttc ccgtacttct acgtcgcggg ctcggtgatc ctcaacatcc gattgcaggt
      361 acatatttag agccatgact aagctaacgg cctccggggc cagcatgatg gccgactccc
      421 agggtccgtt gcggcgcggc ggagcagcca atggcgagcc ccacagtctc gcgagagtgc
      481 tcaggcgctc ttcgtggctg ccctcttagc tgctagcgga gctcctcagg gggcggccgg
      541 gagcctacaa tccctagaaa gagaatacgc tgttccggaa acagaactgc agttaagacc
      601 ctcgaaaaca tctaagaaag tgtgcatcct aaaacacctg acgaatttca gaatgtgaca
      661 aagcgcagag gatgcattat ttcaaaacaa aacagaaggc taaaatttgc aggaaaaaga
      721 aaatcagtaa accgggaatc ctcggactgg attgtaagca agatttcaat gaataagaag
      781 ctgaaggtat taaggctgtg atatagaagg tacatatttc atcccacaag agaaaacaat
      841 aataatcaga aattttcggt gaaaaaaacg caaaactgta caggaaaatc atcctccaag
      901 taccagacat aaaatgctgc aagcttttga actaatggcg agagtgtaag aaaatgggct
      961 ctacttcagt gatcctgtgg caggacgtgg atcaagactt ggaaccgcag aaaacgaaat
     1021 cccatagtag cacaaagctt ggctgttcag tgaataacat ttaaataatc gtaaaataca
     1081 aatgttgttt atggttttta ttgtttaagg gcatacttaa ttatggttac aaagtggagt
     1141 gcaaatgtta tttaccatgt tttaaaaata cagccggaaa atacaagtgg gaatgttgaa
     1201 ggagggcggg ggaagtaaat ggaatggggg ttatgtcctt ataaagtgga aacttgaaag
     1261 gtactgtctg ttgttgagtg gggaaagaca tttttattac ttacagggta gccataaagt
     1321 ttctaaaacg gtaatatatt aaagagggag agtggtaggg gagaacagta tgaagtcaac
     1381 aggaaatggc taaagatgga gagctcaggt agaatagttt aaaaaatgaa aattgataga
     1441 gtacctggtg tatttgaata cagcctagag agctttcatt ttccaaagag tgtggggata
     1501 aattagtgaa tgcatatttt tcaaaattaa gaaaacagaa catataattt tgaacgctga
     1561 gaaaaataaa aatttaaaaa ctacactgta tacacggtat acctcaactg tgaataatag
     1621 tagtcatgta aagtcagtca taattatgta aatactgaat actgatttta caacaaatga
     1681 ttctataacg ctgggaggat gggagaaaag agatgtgtgt gtgtgtaatg gtggtgagcc
     1741 aatcaagatc tgatatagaa aaatgcagaa aaaggagtat acacatgttt tcttcggatt
     1801 aaaaaaacta ataataaatc accaagagtg gtaaagtttt aaatcaagat ctgatataga
     1861 aaagtgcaga aaaagtagta tacgcatttt ttttttcagg aaaaaattaa ctaataaacc
     1921 actaagaggg gtaaagtgtt aaaatagttg cattgttcta tattccactc attgtgtcca
     1981 gcaaacagtg ttctatggct ttaagtagta agcatcttgc cccgtccaac accatgtctg
     2041 gcctagggta attgttcttt ctagtcttta ttctttgtct ccagccaaac tccatttggg
     2101 cacattctcc tatagccttt tctacctgaa gatactctgt gttttaaagc taagcttagg
     2161 tggcgctttt tccattaaat ttttcctgga ttccactgac catataggag ctcacttctt
     2221 ttaatccata aggccatttt cataggttgc cttatttttc cctaatcgtg catcaactgt
     2281 ctgttttata tacccaagac aggtttccta gactgcgata agccaaaaca ttttagtcta
     2341 aaatatcaga agtgtagttt aatcaatgaa atagtaatac caagggattt agaatcgtgg
     2401 acatcactgt ttcccagagc actgatgtcc caatttgtaa cacaaaagac tgtctagtct
     2461 taatcctgaa atggtgacag agtaggatgc tccatttggg tgactatgtg aacatattcc
     2521 tataactttt ttcctcacat cagtcatttg ttaaaccgaa gatgaagaaa cagactttgt
     2581 atttattaca tcctccaaca taattggcag ctctgtgagg gaagacacta tatcctattc
     2641 aattttacac ccggtagtaa cagtatgtgt gtgtactgta tatatacata tatatataca
     2701 tacacatata taaatttaag tagtaactat atatgtatat atgtatagtt actacttact
     2761 atatatgtat acagtatata agtatatatg tatagttact acttacaata tatgcataaa
     2821 gttacagctt acatttacct cgtaatatat gtatatatat atattaggag ttaaatgtat
     2881 taggaggtaa atgtaaactc tgtggtttat catttattca caattgctct taattcttgg
     2941 ggtatagttt gcctcctaca tgatgcaatt cagtgaaatt cccaggagac aaaacaagat
     3001 tttgacctga ataaaccact tattgttgta attcacaagt gagtttattc ttcctggcac
     3061 acttccaggt aatatccatt aggctaagga ttttgtttgt tcactgttct atccccaagc
     3121 ctagagcact gcccagtgcg gaatagctaa taaatattgt tgaatggata gatgaatggc
     3181 aattttgttg gtatgctcta catagtcagc agtcaataaa ggaaacatat attcgttcct
     3241 gataataaga tgattcactt tattgcccat aaattgggct ttttcaggcc atcatgcacg
     3301 ttgattgatc cagagatccc tcaagcatga aaaagcagag acataggtgg tatagttatt
     3361 atcaatagag ataagaaatg tagctggcaa aaaaaaaaat gggaaacgat gcgttacagc
     3421 ttattttaac tataaaagga aaacagtgaa catagcaaca tatgtaacct aagggatagg
     3481 ggaaaagttg tttttttttt tttaattctg ggtaaaaata catgtgatta cttgacaaat
     3541 agcatatcat taccatcagc atcattttta aaatatattg agtttttaat accaggaact
     3601 atgaaaaact atttatatac atgagctccg taattctcac atataccctg tgaggaaaac
     3661 atttttatca tttttcagag aagcaaaccg ggatttagag aggttaagta aattcctaag
     3721 gtcatgataa ccaaccagac ctcaaatgaa tctccagtaa ttcctaaagt tatatttcat
     3781 aaggagttca attttcttaa atgtgtagat aattacaaat aattctgttt ctcaaatttc
     3841 tggacagaaa tattacctgg gtaatagtta ttttttttaa cataactatt gagggtcttt
     3901 catactaaaa tataaatatt taacatgatt tgatatgtaa gttcaagtat tttatactct
     3961 ctgcagcctt aaacctattg gcttatttta ttagagggtt ggtgggattg agggatatgg
     4021 gagcaaaggg agagagagga aagaacgttg tcctcagaat ggaagggaaa cactttcctg
     4081 tgctacccag agtagagatc agacaatgtt aaattttgaa gccatgtctg ttcctgtcct
     4141 gaggatccct aactaaattt tgttagaaaa tcttgcagtt tgcttttaat gggagatctt
     4201 tctggcagga catcaatagc ttttgatagc gtcaagaaga aaataaagtt acatgcagaa
     4261 gcataaaggg gtaggatgaa agttgaggaa tatagggaca aaagatgagg gaaaggaata
     4321 tcctaatact tggaagtttg agcatggaaa gtagtctaaa gacgacttgg gaagttccaa
     4381 gaaaatgaac caagaaaaga acctctgcaa gaactatgag aattcccaac aattgggttg
     4441 gattgattca tattagtcta ttacttgggt taccttgagt gtggggattc ttcttgcagt
     4501 tttaacactt gtactatggt ctgaatgtgc cccccaaaaa ttcacatgtt ggcatttaac
     4561 ccccaaagtg atgatctcag gagatgggac ctttgggagg tgatcaggtc ataaagatga
     4621 aaccctcgtg aatgggatta gtgcctttat aaaggagacc ccaaaataat tcccttaccc
     4681 cttttgccat gtaaggttat agggaaaagt catctatgaa caaggaaatg aaccctcacc
     4741 agataccaaa tttgtgaatg cctggatctt ggacttccca gcttctagaa ctataagaaa
     4801 taaatttctg ttgttcataa gca
//
