LOCUS       NM_003070               5748 bp    mRNA    linear   PRI 08-OCT-2024
DEFINITION  Homo sapiens SWI/SNF related BAF chromatin remodeling complex
            subunit ATPase 2 (SMARCA2), transcript variant 1, mRNA.
ACCESSION   NM_003070
VERSION     NM_003070.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5748)
  AUTHORS   Zhang,Z., Li,Q., Sun,S., Li,Z., Cui,Z., Liu,Q., Zhang,Y., Xiong,S.
            and Zhang,S.
  TITLE     Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and
            construction of a nomogram prognostic model
  JOURNAL   Int J Clin Oncol 28 (11), 1487-1500 (2023)
   PUBMED   37634210
  REMARK    GeneRIF: Expression of SMARCA2 and SMARCA4 in gastric
            adenocarcinoma and construction of a nomogram prognostic model.
REFERENCE   2  (bases 1 to 5748)
  AUTHORS   Pintacuda,G., Hsu,Y.H., Tsafou,K., Li,K.W., Martin,J.M.,
            Riseman,J., Biagini,J.C., Ching,J.K.T., Mena,D.,
            Gonzalez-Lozano,M.A., Egri,S.B., Jaffe,J., Smit,A.B., Fornelos,N.,
            Eggan,K.C. and Lage,K.
  TITLE     Protein interaction studies in human induced neurons indicate
            convergent biology underlying autism spectrum disorders
  JOURNAL   Cell Genom 3 (3), 100250 (2023)
   PUBMED   36950384
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5748)
  AUTHORS   Zhang,Z., Li,Q., Sun,S., Li,Z., Cui,Z.G., Zhang,M., Liu,Q.,
            Zhang,Y., Xiong,S. and Zhang,S.
  TITLE     Clinicopathological and prognostic significance of SWI/SNF complex
            subunits in undifferentiated gastric carcinoma
  JOURNAL   World J Surg Oncol 20 (1), 383 (2022)
   PUBMED   36464671
  REMARK    GeneRIF: Clinicopathological and prognostic significance of SWI/SNF
            complex subunits in undifferentiated gastric carcinoma.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5748)
  AUTHORS   Zhang,X., Chen,H., Song,Y., Chen,Z., Liu,X., Rong,P. and Ma,R.
  TITLE     Ten-year follow-up of Nicolaides-Baraitser syndrome with a de novo
            mutation and analysis of 58 gene loci of SMARCA2-associated NCBRS
  JOURNAL   Mol Genet Genomic Med 10 (9), e2009 (2022)
   PUBMED   35811451
  REMARK    GeneRIF: Ten-year follow-up of Nicolaides-Baraitser syndrome with a
            de novo mutation and analysis of 58 gene loci of SMARCA2-associated
            NCBRS.
REFERENCE   5  (bases 1 to 5748)
  AUTHORS   Sun,S., Li,Q., Zhang,Z., Xiong,S., Zhang,Y., Liu,Q., Li,Z., Yang,F.
            and Zhang,S.
  TITLE     SMARCA2 deficiency in NSCLC: a clinicopathologic and
            immunohistochemical analysis of a large series from a single
            institution
  JOURNAL   Environ Health Prev Med 27, 3 (2022)
   PUBMED   35289322
  REMARK    GeneRIF: SMARCA2 deficiency in NSCLC: a clinicopathologic and
            immunohistochemical analysis of a large series from a single
            institution.
REFERENCE   6  (bases 1 to 5748)
  AUTHORS   Aves,S.J., Hindley,J., Phear,G.A. and Tongue,N.
  TITLE     A fission yeast gene mapping close to suc1 encodes a protein
            containing two bromodomains
  JOURNAL   Mol Gen Genet 248 (4), 491-498 (1995)
   PUBMED   7565614
REFERENCE   7  (bases 1 to 5748)
  AUTHORS   Chiba,H., Muramatsu,M., Nomoto,A. and Kato,H.
  TITLE     Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and
            Drosophila brahma are transcriptional coactivators cooperating with
            the estrogen receptor and the retinoic acid receptor
  JOURNAL   Nucleic Acids Res 22 (10), 1815-1820 (1994)
   PUBMED   8208605
REFERENCE   8  (bases 1 to 5748)
  AUTHORS   Muchardt,C., Yaniv,M. and Mattei,M.G.
  TITLE     Assignment of HBRM, the human homolog of S. cerevisiae SNF2/SWI2
            and Drosophila brm genes, to chromosome region 9p23-p24, by in situ
            hybridization
  JOURNAL   Mamm Genome 5 (4), 241-243 (1994)
   PUBMED   8012116
REFERENCE   9  (bases 1 to 5748)
  AUTHORS   Muchardt,C. and Yaniv,M.
  TITLE     A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and
            Drosophila brm genes potentiates transcriptional activation by the
            glucocorticoid receptor
  JOURNAL   EMBO J 12 (11), 4279-4290 (1993)
   PUBMED   8223438
REFERENCE   10 (bases 1 to 5748)
  AUTHORS   Abdul-Rahman,O.
  TITLE     Nicolaides-Baraitser Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   26468571
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC040029.1, BC068252.1,
            X72889.1, AL558829.3, BC066596.1 and AK094076.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_003070.4.
            
            Summary: The protein encoded by this gene is a member of the
            SWI/SNF family of proteins and is highly similar to the brahma
            protein of Drosophila. Members of this family have helicase and
            ATPase activities and are thought to regulate transcription of
            certain genes by altering the chromatin structure around those
            genes. The encoded protein is part of the large ATP-dependent
            chromatin remodeling complex SNF/SWI, which is required for
            transcriptional activation of genes normally repressed by
            chromatin. Alternatively spliced transcript variants encoding
            different isoforms have been found for this gene, which contains a
            trinucleotide repeat (CAG) length polymorphism. [provided by
            RefSeq, Jan 2014].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: X72889.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1965299, SAMEA1966682 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000349721.8/ ENSP00000265773.5
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-988               BC040029.1         6-993
            989-1758            BC068252.1         1117-1886
            1759-2224           X72889.1           1875-2340
            2225-2301           BC068252.1         2353-2429
            2302-3765           X72889.1           2418-3881
            3766-4058           BC068252.1         3720-4012
            4059-4272           X72889.1           4175-4388
            4273-4293           BC068252.1         4227-4247
            4294-4359           AL558829.3         369-434
            4360-4448           BC068252.1         4260-4348
            4449-4731           BC068252.1         4350-4632
            4732-5702           BC066596.1         613-1583
            5703-5741           X72889.1           5818-5856
            5742-5748           AK094076.1         2232-2238
FEATURES             Location/Qualifiers
     source          1..5748
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p24.3"
     gene            1..5748
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /note="SWI/SNF related BAF chromatin remodeling complex
                     subunit ATPase 2"
                     /db_xref="GeneID:6595"
                     /db_xref="HGNC:HGNC:11098"
                     /db_xref="MIM:600014"
     exon            1..58
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            59..319
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..4867
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /note="isoform a is encoded by transcript variant 1;
                     global transcription activator homologous sequence;
                     SNF2-alpha; sucrose nonfermenting 2-like protein 2;
                     SNF2/SWI2-like protein 2; SWI/SNF-related
                     matrix-associated actin-dependent regulator of chromatin
                     a2; brahma homolog; probable global transcription
                     activator SNF2L2; BAF190B; protein brahma homolog;
                     BRG1-associated factor 190B; ATP-dependent helicase
                     SMARCA2; putative global transcription activator SNF2L2;
                     SWI/SNF related, matrix associated, actin dependent
                     regulator of chromatin, subfamily a, member 2"
                     /codon_start=1
                     /product="probable global transcription activator SNF2L2
                     isoform a"
                     /protein_id="NP_003061.3"
                     /db_xref="CCDS:CCDS34977.1"
                     /db_xref="GeneID:6595"
                     /db_xref="HGNC:HGNC:11098"
                     /db_xref="MIM:600014"
                     /translation="MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMM
                     GPSPGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPP
                     HPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGD
                     PQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ
                     QQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQ
                     KLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQLQQKQSRISPIQKP
                     QGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQL
                     RQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQE
                     YLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA
                     EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKA
                     EENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMN
                     PGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAK
                     QDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYN
                     NNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPS
                     VVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRM
                     KNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFN
                     APFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSA
                     LQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFA
                     EHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAF
                     RNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDS
                     DWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMF
                     DQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRR
                     EDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL
                     TEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSP
                     NPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKEL
                     PEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIV
                     LQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKG
                     KGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE"
     exon            320..449
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            450..884
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1140
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1267
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1268..1441
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1615
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1786
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1840
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1841..1971
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2029
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2130
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2278
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2442
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2509
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2620
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2621..2863
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2864..2977
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3085
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3172
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3173..3219
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3220..3386
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3387..3550
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3551..3778
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3779..3856
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            3857..4075
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4076..4293
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4294..4347
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4348..4453
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4454..4555
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4556..4688
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4689..4831
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     exon            4832..5748
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5680..5685
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /note="hexamer: AATAAA"
     polyA_site      5702
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /note="major polyA site"
     regulatory      5726..5731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
                     /note="hexamer: AATAAA"
     polyA_site      5748
                     /gene="SMARCA2"
                     /gene_synonym="BAF190; BIS; BRM; hBRM; hSNF2a; NCBRS;
                     SNF2; SNF2L2; SNF2LA; Sth1p; SWI2"
ORIGIN      
        1 gtactctggg tgactcagag agggaagaga ttcagccagc acactcctcg cgagcaagca
       61 ttactctact gactggcaga gacaggagag gtagatgtcc acgcccacag accctggtgc
      121 gatgccccac ccagggcctt cgccggggcc tgggccttcc cctgggccaa ttcttgggcc
      181 tagtccagga ccaggaccat ccccaggttc cgtccacagc atgatggggc caagtcctgg
      241 acctccaagt gtctcccatc ctatgccgac gatggggtcc acagacttcc cacaggaagg
      301 catgcatcaa atgcataagc ccatcgatgg tatacatgac aaggggattg tagaagacat
      361 ccattgtgga tccatgaagg gcactggtat gcgaccacct cacccaggca tgggccctcc
      421 ccagagtcca atggatcaac acagccaagg ttatatgtca ccacacccat ctccattagg
      481 agccccagag cacgtctcca gccctatgtc tggaggaggc ccaactccac ctcagatgcc
      541 accaagccag ccgggggccc tcatcccagg tgatccgcag gccatgagcc agcccaacag
      601 aggtccctca cctttcagtc ctgtccagct gcatcagctt cgagctcaga ttttagctta
      661 taaaatgctg gcccgaggcc agcccctccc cgaaacgctg cagcttgcag tccaggggaa
      721 aaggacgttg cctggcttgc agcaacaaca gcagcagcaa cagcagcagc agcagcagca
      781 gcagcagcag cagcagcagc aacagcagcc gcagcagcag ccgccgcaac cacagacgca
      841 gcaacaacag cagccggccc ttgttaacta caacagacca tctggcccgg ggccggagct
      901 gagcggcccg agcaccccgc agaagctgcc ggtgcccgcg cccggcggcc ggccctcgcc
      961 cgcgcccccc gcagccgcgc agccgcccgc ggccgcagtg cccgggccct cagtgccgca
     1021 gccggccccg gggcagccct cgcccgtcct ccagctgcag cagaagcaga gccgcatcag
     1081 ccccatccag aaaccgcaag gcctggaccc cgtggaaatt ctgcaagagc gggaatacag
     1141 acttcaggcc cgcatagctc ataggataca agaactggaa aatctgcctg gctctttgcc
     1201 accagattta agaaccaaag caaccgtgga actaaaagca cttcggttac tcaatttcca
     1261 gcgtcagctg agacaggagg tggtggcctg catgcgcagg gacacgaccc tggagacggc
     1321 tctcaactcc aaagcataca aacggagcaa gcgccagact ctgagagaag ctcgcatgac
     1381 cgagaagctg gagaagcagc agaagattga gcaggagagg aaacgccgtc agaaacacca
     1441 ggaatacctg aacagtattt tgcaacatgc aaaagatttt aaggaatatc atcggtctgt
     1501 ggccggaaag atccagaagc tctccaaagc agtggcaact tggcatgcca acactgaaag
     1561 agagcagaag aaggagacag agcggattga aaaggagaga atgcggcgac tgatggctga
     1621 agatgaggag ggttatagaa aactgattga tcaaaagaaa gacaggcgtt tagcttacct
     1681 tttgcagcag accgatgagt atgtagccaa tctgaccaat ctggtttggg agcacaagca
     1741 agcccaggca gccaaagaga agaagaagag gaggaggagg aagaagaagg ctgaggagaa
     1801 tgcagagggt ggggagtctg ccctgggacc ggatggagag cccatagatg agagcagcca
     1861 gatgagtgac ctccctgtca aagtgactca cacagaaacc ggcaaggttc tgttcggacc
     1921 agaagcaccc aaagcaagtc agctggacgc ctggctggaa atgaatcctg gttatgaagt
     1981 tgcccctaga tctgacagtg aagagagtga ttctgattat gaggaagagg atgaggaaga
     2041 agagtccagt aggcaggaaa ccgaagagaa aatactcctg gatccaaata gcgaagaagt
     2101 ttctgagaag gatgctaagc agatcattga gacagctaag caagacgtgg atgatgaata
     2161 cagcatgcag tacagtgcca ggggctccca gtcctactac accgtggctc atgccatctc
     2221 ggagagggtg gagaaacagt ctgccctcct aattaatggg accctaaagc attaccagct
     2281 ccagggcctg gaatggatgg tttccctgta taataacaac ttgaacggaa tcttagccga
     2341 tgaaatgggg cttggaaaga ccatacagac cattgcactc atcacttatc tgatggagca
     2401 caaaagactc aatggcccct atctcatcat tgttcccctt tcgactctat ctaactggac
     2461 atatgaattt gacaaatggg ctccttctgt ggtgaagatt tcttacaagg gtactcctgc
     2521 catgcgtcgc tcccttgtcc cccagctacg gagtggcaaa ttcaatgtcc tcttgactac
     2581 ttatgagtat attataaaag acaagcacat tcttgcaaag attcggtgga aatacatgat
     2641 agtggacgaa ggccaccgaa tgaagaatca ccactgcaag ctgactcagg tcttgaacac
     2701 tcactatgtg gcccccagaa ggatcctctt gactgggacc ccgctgcaga ataagctccc
     2761 tgaactctgg gccctcctca acttcctcct cccaacaatt tttaagagct gcagcacatt
     2821 tgaacaatgg ttcaatgctc catttgccat gactggtgaa agggtggact taaatgaaga
     2881 agaaactata ttgatcatca ggcgtctaca taaggtgtta agaccatttt tactaaggag
     2941 actgaagaaa gaagttgaat cccagcttcc cgaaaaagtg gaatatgtga tcaagtgtga
     3001 catgtcagct ctgcagaaga ttctgtatcg ccatatgcaa gccaagggga tccttctcac
     3061 agatggttct gagaaagata agaaggggaa aggaggtgct aagacactta tgaacactat
     3121 tatgcagttg agaaaaatct gcaaccaccc atatatgttt cagcacattg aggaatcctt
     3181 tgctgaacac ctaggctatt caaatggggt catcaatggg gctgaactgt atcgggcctc
     3241 agggaagttt gagctgcttg atcgtattct gccaaaattg agagcgacta atcaccgagt
     3301 gctgcttttc tgccagatga catctctcat gaccatcatg gaggattatt ttgcttttcg
     3361 gaacttcctt tacctacgcc ttgatggcac caccaagtct gaagatcgtg ctgctttgct
     3421 gaagaaattc aatgaacctg gatcccagta tttcattttc ttgctgagca caagagctgg
     3481 tggcctgggc ttaaatcttc aggcagctga tacagtggtc atctttgaca gcgactggaa
     3541 tcctcatcag gatctgcagg cccaagaccg agctcaccgc atcgggcagc agaacgaggt
     3601 ccgggtactg aggctctgta ccgtgaacag cgtggaggaa aagatcctcg cggccgcaaa
     3661 atacaagctg aacgtggatc agaaagtgat ccaggcgggc atgtttgacc aaaagtcttc
     3721 aagccacgag cggagggcat tcctgcaggc catcttggag catgaggagg aaaatgagga
     3781 agaagatgaa gtaccggacg atgagactct gaaccaaatg attgctcgac gagaagaaga
     3841 atttgacctt tttatgcgga tggacatgga ccggcggagg gaagatgccc ggaacccgaa
     3901 acggaagccc cgtttaatgg aggaggatga gctgccctcc tggatcatta aggatgacgc
     3961 tgaagtagaa aggctcacct gtgaagaaga ggaggagaaa atatttggga gggggtcccg
     4021 ccagcgccgt gacgtggact acagtgacgc cctcacggag aagcagtggc taagggccat
     4081 cgaagacggc aatttggagg aaatggaaga ggaagtacgg cttaagaagc gaaaaagacg
     4141 aagaaatgtg gataaagatc ctgcaaaaga agatgtggaa aaagctaaga agagaagagg
     4201 ccgccctccc gctgagaaac tgtcaccaaa tccccccaaa ctgacaaagc agatgaacgc
     4261 tatcatcgat actgtgataa actacaaaga taggtgtaac gtggagaagg tgcccagtaa
     4321 ttctcagttg gaaatagaag gaaacagttc agggcgacag ctcagtgaag tcttcattca
     4381 gttaccttca aggaaagaat taccagaata ctatgaatta attaggaagc cagtggattt
     4441 caaaaaaata aaggaaagga ttcgtaatca taagtaccgg agcctaggcg acctggagaa
     4501 ggatgtcatg cttctctgtc acaacgctca gacgttcaac ctggagggat cccagatcta
     4561 tgaagactcc atcgtcttac agtcagtgtt taagagtgcc cggcagaaaa ttgccaaaga
     4621 ggaagagagt gaggatgaaa gcaatgaaga ggaggaagag gaagatgaag aagagtcaga
     4681 gtccgaggca aaatcagtca aggtgaaaat taagctcaat aaaaaagatg acaaaggccg
     4741 ggacaaaggg aaaggcaaga aaaggccaaa tcgaggaaaa gccaaacctg tagtgagcga
     4801 ttttgacagc gatgaggagc aggatgaacg tgaacagtca gaaggaagtg ggacggatga
     4861 tgagtgatca gtatggacct ttttccttgg tagaactgaa ttccttcctc ccctgtctca
     4921 tttctaccca gtgagttcat ttgtcatata ggcactgggt tgtttctata tcatcatcgt
     4981 ctataaacta gctttaggat agtgccagac aaacatatga tatcatggtg taaaaaacac
     5041 acacatacac aaatatttgt aacatattgt gaccaaatgg gcctcaaaga ttcagattga
     5101 aacaaacaaa aagcttttga tggaaaatat gtgggtggat agtatatttc tatgggtggg
     5161 tctaatttgg taacggtttg attgtgcctg gttttatcac ctgttcagat gagaagattt
     5221 ttgtcttttg tagcactgat aaccaggaga agccattaaa agccactggt tattttattt
     5281 ttcatcaggc aattttcgag gtttttattt gttcggtatt gtttttttac actgtggtac
     5341 atataagcaa ctttaatagg tgataaatgt acagtagtta gatttcacct gcatatacat
     5401 ttttccattt tatgctctat gatctgaaca aaagcttttt gaattgtata agatttatgt
     5461 ctactgtaaa cattgcttaa tttttttgct cttgatttaa aaaaaagttt tgttgaaagc
     5521 gctattgaat attgcaatct atatagtgta ttggatggct tcttttgtca ccctgatctc
     5581 ctatgttacc aatgtgtatc gtctccttct ccctaaagtg tacttaatct ttgctttctt
     5641 tgcacaatgt ctttggttgc aagtcataag cctgaggcaa ataaaattcc agtaatttcg
     5701 aagaatgtgg tgttggtgct ttcctaataa agaaataatt tagcttga
//
