LOCUS       NM_005901              34626 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1,
            mRNA.
ACCESSION   NM_005901
VERSION     NM_005901.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 34626)
  AUTHORS   Tang,Z., Zhang,D., Yao,C., Jiang,M., Wang,C., Chen,Z., Yu,H.,
            Xue,C., Liu,Y., Shi,Y., Zhang,L., Wang,X. and Wei,Z.
  TITLE     TIPE2 inhibits the migration and invasion of epithelial ovarian
            cancer cells by targeting Smad2 to reverse TGF-beta1-induced EMT
  JOURNAL   FASEB J 38 (17), e70045 (2024)
   PUBMED   39259551
  REMARK    GeneRIF: TIPE2 inhibits the migration and invasion of epithelial
            ovarian cancer cells by targeting Smad2 to reverse
            TGF-beta1-induced EMT.
REFERENCE   2  (bases 1 to 34626)
  AUTHORS   Chen,J., Niu,Z., Yao,L., Xiao,M. and Fan,J.
  TITLE     cDNA cloning and sequencing of MH2 domain of Smad2 from human
            dental pulp cells
  JOURNAL   Chin J Dent Res 2 (2), 14-18 (1999)
   PUBMED   10863401
REFERENCE   3  (bases 1 to 34626)
  AUTHORS   Yagi,K., Goto,D., Hamamoto,T., Takenoshita,S., Kato,M. and
            Miyazono,K.
  TITLE     Alternatively spliced variant of Smad2 lacking exon 3. Comparison
            with wild-type Smad2 and Smad3
  JOURNAL   J Biol Chem 274 (2), 703-709 (1999)
   PUBMED   9873005
REFERENCE   4  (bases 1 to 34626)
  AUTHORS   Takenoshita,S., Mogi,A., Nagashima,M., Yang,K., Yagi,K., Hanyu,A.,
            Nagamachi,Y., Miyazono,K. and Hagiwara,K.
  TITLE     Characterization of the MADH2/Smad2 gene, a human Mad homolog
            responsible for the transforming growth factor-beta and activin
            signal transduction pathway
  JOURNAL   Genomics 48 (1), 1-11 (1998)
   PUBMED   9503010
REFERENCE   5  (bases 1 to 34626)
  AUTHORS   Nakao,A., Roijer,E., Imamura,T., Souchelnytskyi,S., Stenman,G.,
            Heldin,C.H. and ten Dijke,P.
  TITLE     Identification of Smad2, a human Mad-related protein in the
            transforming growth factor beta signaling pathway
  JOURNAL   J Biol Chem 272 (5), 2896-2900 (1997)
   PUBMED   9006934
REFERENCE   6  (bases 1 to 34626)
  AUTHORS   Zhang,Y., Feng,X., We,R. and Derynck,R.
  TITLE     Receptor-associated Mad homologues synergize as effectors of the
            TGF-beta response
  JOURNAL   Nature 383 (6596), 168-172 (1996)
   PUBMED   8774881
REFERENCE   7  (bases 1 to 34626)
  AUTHORS   Eppert,K., Scherer,S.W., Ozcelik,H., Pirone,R., Hoodless,P.,
            Kim,H., Tsui,L.C., Bapat,B., Gallinger,S., Andrulis,I.L.,
            Thomsen,G.H., Wrana,J.L. and Attisano,L.
  TITLE     MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related
            protein that is functionally mutated in colorectal carcinoma
  JOURNAL   Cell 86 (4), 543-552 (1996)
   PUBMED   8752209
REFERENCE   8  (bases 1 to 34626)
  AUTHORS   Riggins,G.J., Thiagalingam,S., Rozenblum,E., Weinstein,C.L.,
            Kern,S.E., Hamilton,S.R., Willson,J.K., Markowitz,S.D.,
            Kinzler,K.W. and Vogelstein,B.
  TITLE     Mad-related genes in the human
  JOURNAL   Nat Genet 13 (3), 347-349 (1996)
   PUBMED   8673135
REFERENCE   9  (bases 1 to 34626)
  AUTHORS   Loeys,B.L. and Dietz,H.C.
  TITLE     Loeys-Dietz Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301312
REFERENCE   10 (bases 1 to 34626)
  AUTHORS   Milewicz,D.M. and Cecchi,A.C.
  TITLE     Heritable Thoracic Aortic Disease Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301299
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC120349.5, BC014840.1,
            AI453799.1 and AC026898.8.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 3, 2019 this sequence version replaced NM_005901.5.
            
            Summary: The protein encoded by this gene belongs to the SMAD, a
            family of proteins similar to the gene products of the Drosophila
            gene 'mothers against decapentaplegic' (Mad) and the C. elegans
            gene Sma. SMAD proteins are signal transducers and transcriptional
            modulators that mediate multiple signaling pathways. This protein
            mediates the signal of the transforming growth factor (TGF)-beta,
            and thus regulates multiple cellular processes, such as cell
            proliferation, apoptosis, and differentiation. This protein is
            recruited to the TGF-beta receptors through its interaction with
            the SMAD anchor for receptor activation (SARA) protein. In response
            to TGF-beta signal, this protein is phosphorylated by the TGF-beta
            receptors. The phosphorylation induces the dissociation of this
            protein with SARA and the association with the family member SMAD4.
            The association with SMAD4 is important for the translocation of
            this protein into the nucleus, where it binds to target promoters
            and forms a transcription repressor complex with other cofactors.
            This protein can also be phosphorylated by activin type 1 receptor
            kinase, and mediates the signal from the activin. Alternatively
            spliced transcript variants have been observed for this gene.
            [provided by RefSeq, May 2012].
            
            Transcript Variant: This variant (1) uses an alternate exon (1b) in
            the 5' UTR compared to variant 2. Both variants 1 and 2 encode the
            same isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.461536.1,
                                           SRR14038196.1234363.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000262160.11/ ENSP00000262160.6
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AC120349.5         28152-28255
            105-2340            BC014840.1         1-2236
            2341-10194          AC120349.5         117569-125422
            10195-10488         AI453799.1         16-309              c
            10489-33368         AC120349.5         125717-148596
            33369-34626         AC026898.8         186038-187295       c
FEATURES             Location/Qualifiers
     source          1..34626
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18q21.1"
     gene            1..34626
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="SMAD family member 2"
                     /db_xref="GeneID:4087"
                     /db_xref="HGNC:HGNC:6768"
                     /db_xref="MIM:601366"
     exon            1..299
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            300..588
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..1756
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mother against DPP homolog 2; Sma- and Mad-related protein
                     2; mothers against decapentaplegic homolog 2; MAD homolog
                     2; SMAD, mothers against DPP homolog 2"
                     /codon_start=1
                     /product="mothers against decapentaplegic homolog 2
                     isoform 1"
                     /protein_id="NP_005892.1"
                     /db_xref="CCDS:CCDS11934.1"
                     /db_xref="GeneID:4087"
                     /db_xref="HGNC:HGNC:6768"
                     /db_xref="MIM:601366"
                     /translation="MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKA
                     VKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLY
                     SFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEV
                     CVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIP
                     ETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCS
                     IAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGR
                     GVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA
                     LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
                     KVLTQMGSPSVRCSSMS"
     exon            589..678
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            679..872
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1007
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1082
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1136
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1349
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1487
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1632
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..34626
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2318..2323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: AATAAA"
     polyA_site      2340
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="major polyA site"
     regulatory      3307..3312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: CATAAA"
     polyA_site      3328
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="major polyA site"
     regulatory      10453..10458
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: ATTAAA"
     polyA_site      10488
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
     regulatory      23130..23135
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: AATAAA"
     polyA_site      23151
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
     regulatory      23162..23167
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: AATAAA"
     polyA_site      23186
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
     regulatory      27352..27357
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: AATAAA"
     polyA_site      27378
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
     regulatory      34609..34614
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
                     /note="hexamer: AATAAA"
     polyA_site      34626
                     /gene="SMAD2"
                     /gene_synonym="CHTD8; hMAD-2; hSMAD2; JV18; JV18-1; LDS6;
                     MADH2; MADR2"
ORIGIN      
        1 gcgcgcgtcc tcaccccctc cttccccgcg ggcggcggcc aggctccctc ccctcccctt
       61 ccctctcctc ccctcccctc ccctctcttc ccctaccctc ccgcgcgccc gggccgccgg
      121 ccgggcccgg gcctgggggc ggggcgggaa gacggcggcc gggagtgttt tcagttccgc
      181 ctccaatcgc ccattcccct cttcccctcc cagccccctc catcccatcg gaagaggaag
      241 gaacaaaagg tcccggaccc cccggatctg acggggcggg acctggcgcc accttgcagg
      301 ttcgatacaa gaggctgttt tcctagcgtg gcttgctgcc tttggtaaga acatgtcgtc
      361 catcttgcca ttcacgccgc cagttgtgaa gagactgctg ggatggaaga agtcagctgg
      421 tgggtctgga ggagcaggcg gaggagagca gaatgggcag gaagaaaagt ggtgtgagaa
      481 agcagtgaaa agtctggtga agaagctaaa gaaaacagga cgattagatg agcttgagaa
      541 agccatcacc actcaaaact gtaatactaa atgtgttacc ataccaagca cttgctctga
      601 aatttgggga ctgagtacac caaatacgat agatcagtgg gatacaacag gcctttacag
      661 cttctctgaa caaaccaggt ctcttgatgg tcgtctccag gtatcccatc gaaaaggatt
      721 gccacatgtt atatattgcc gattatggcg ctggcctgat cttcacagtc atcatgaact
      781 caaggcaatt gaaaactgcg aatatgcttt taatcttaaa aaggatgaag tatgtgtaaa
      841 cccttaccac tatcagagag ttgagacacc agttttgcct ccagtattag tgccccgaca
      901 caccgagatc ctaacagaac ttccgcctct ggatgactat actcactcca ttccagaaaa
      961 cactaacttc ccagcaggaa ttgagccaca gagtaattat attccagaaa cgccacctcc
     1021 tggatatatc agtgaagatg gagaaacaag tgaccaacag ttgaatcaaa gtatggacac
     1081 aggctctcca gcagaactat ctcctactac tctttcccct gttaatcata gcttggattt
     1141 acagccagtt acttactcag aacctgcatt ttggtgttcg atagcatatt atgaattaaa
     1201 tcagagggtt ggagaaacct tccatgcatc acagccctca ctcactgtag atggctttac
     1261 agacccatca aattcagaga ggttctgctt aggtttactc tccaatgtta accgaaatgc
     1321 cacggtagaa atgacaagaa ggcatatagg aagaggagtg cgcttatact acataggtgg
     1381 ggaagttttt gctgagtgcc taagtgatag tgcaatcttt gtgcagagcc ccaattgtaa
     1441 tcagagatat ggctggcacc ctgcaacagt gtgtaaaatt ccaccaggct gtaatctgaa
     1501 gatcttcaac aaccaggaat ttgctgctct tctggctcag tctgttaatc agggttttga
     1561 agccgtctat cagctaacta gaatgtgcac cataagaatg agttttgtga aagggtgggg
     1621 agcagaatac cgaaggcaga cggtaacaag tactccttgc tggattgaac ttcatctgaa
     1681 tggacctcta cagtggttgg acaaagtatt aactcagatg ggatcccctt cagtgcgttg
     1741 ctcaagcatg tcataaagct tcaccaatca agtcccatga aaagacttaa tgtaacaact
     1801 cttctgtcat agcattgtgt gtggtcccta tggactgttt actatccaaa agttcaagag
     1861 agaaaacagc acttgaggtc tcatcaatta aagcaccttg tggaatctgt ttcctatatt
     1921 tgaatattag atgggaaaat tagtgtctag aaatactctc ccattaaaga ggaagagaag
     1981 attttaaaga cttaatgatg tcttattggg cataaaactg agtgtcccaa aggtttatta
     2041 ataacagtag tagttatgtg tacaggtaat gtatcatgat ccagtatcac agtattgtgc
     2101 tgtttatata catttttagt ttgcatagat gaggtgtgtg tgtgcgctgc ttcttgatct
     2161 aggcaaacct ttataaagtt gcagtaccta atctgttatt cccacttctc tgttattttt
     2221 gtgtgtcttt tttaatatat aatatatatc aagattttca aattatttag aagcagattt
     2281 tcctgtagaa aaactaattt ttctgccttt taccaaaaat aaactcttgg gggaagaaaa
     2341 gtggattaac ttttgaaatc cttgacctta atgtgttcag tggggcttaa acagtcattc
     2401 tttttgtggt tttttgtttt tttttgtttt tttttttaac tgctaaatct tattataagg
     2461 aaaccatact gaaaaccttt ccaagcctct tttttccatt cccatttttg tcctcataat
     2521 caaaacagca taacatgaca tcatcaccag taatagttgc attgatactg ctggcaccag
     2581 ttaattctgg gatacagtaa gaattcatat ggagaaagtc cctttgtctt atgcccaaat
     2641 ttcaacagga ataattggct tgtataatct agcagtctgt tgatttatcc ttccacctca
     2701 taaaaaatgc ataggtggca gtataattat tttcagggat atgctagaat tacttccaca
     2761 tatttatccc tttttaaaaa agctaatcta taaataccgt ttttccaaag gtattttaca
     2821 atatttcaac agcagacctt ctgctcttcg agtagtttga tttggtttag taaccagatt
     2881 gcattatgaa atgggccttt tgtaaatgta attgtttctg caaaatacct agaaaagtga
     2941 tgctgaggta ggatcagcag atatgggcca tctgttttta aagtatgttg tattcagttt
     3001 ataaattgat tgttattcta cacataatta tgaattcaga attttaaaaa ttgggggaaa
     3061 agccatttat ttagcaagtt ttttagctta taagttacct gcagtctgag ctgttcttaa
     3121 ctgatcctgg ttttgtgatt gacaatattt catgctctgt agtgagagga gatttccgaa
     3181 actctgttgc tagttcattc tgcagcaaat aattattatg tctgatgttg actcattgca
     3241 gtttaaacat ttcttcttgt ttgcatctta gtagaaatgg aaaataacca ctcctggtcg
     3301 tcttttcata aattttcata tttttgaagc tgtctttggt acttgttctt tgaaatcata
     3361 tccacctgtc tctataggta tcattttcaa tactttcaac atttggtggt tttctattgg
     3421 gtactcccca ttttcctata tttgtgtgta tatgtatgtg ttcatgtaaa tttggtatag
     3481 taatttttta ttcattcaac aaatatttat tgttcacctg tttgtaccag gaacttttct
     3541 tagtctttgg gtaaaggtga acaagacaac tacagttcct gcctttgctg agacagcagt
     3601 tacactaacc cttaattatc ttacttgtct atgaaggaga taaacagggt actgtactgg
     3661 agaataacag atgggatgct tcaggtagga catcaaggaa agcctctaag gaaaggatgc
     3721 atgagctaac acctgacatt aaagaagcaa gccaagtgag gagccagggg agataagcat
     3781 tcctggcaaa gagaatagca tcaaatgcaa aaaggttcac actaaaggaa actcctgatt
     3841 aggtattaat gctttataca gaaacctcta tacaaatcca aacttgaaga tcagaatggt
     3901 tctacagttc ataacatttt gaaggtggcc ttattttgtg atagtctgct tcatgtgatt
     3961 ctcactaaca tatctccttc ctcaaccttt gctgtaaaaa tttcatttgc accacatcag
     4021 tactacttaa tttaacaagc ttttgttgtg taagctctca ctgttttagt gccctgctgc
     4081 ttgcttccag actttgtgct gtccagtaat tatgtcttcc actacccatc ttgtgagcag
     4141 agtaaatgtc ctaggtaata ccactatcag gcctgtagga gatactcagt ggagcctctg
     4201 cccttctttt tcttacttga gaacttgtaa tggtgttagg gaacagttgt aggggcagaa
     4261 aacaactctg aaagtggtag aaggtcctga tcttggtggt tactcttgca ttactgtgtt
     4321 aggtcaagca gtgcctacta tgctgtttca gtagtggagc gcatctctac agttctgatg
     4381 cgatttttct gtacagtatg aaattgggac tcaactcttt gaaaacacct attgagcagt
     4441 tatacctgtt gagcagttta cttcctggtt gtaattacat ttgtgtgaat gtgtttgatg
     4501 ctttttaacg agatgatgtt ttttgtattt tatctactgt ggcctgattt tttttttgtt
     4561 ttctgcccct ccccccattt ataggtgtgg ttttcatttt tctaagtgat agaatcccct
     4621 ctttgttgaa tttttgtctt tatttaaatt agcaacatta cttaggattt attcttcaca
     4681 atactgttaa ttttctagga atgatgacct gagaaccgaa tggccatgct ttctatcaca
     4741 tttctaagat gagtaatatt ttttccagta ggttccacag agacaccttg ggggctggct
     4801 taggggaggc tgttggagtt ctcactgact tagtggcata tttattctgt actgaagaac
     4861 tgcatggggt ttcttttgga aagagtttca ttgctttaaa aagaagctca gaaagtcttt
     4921 ataaccactg gtcaacgatt agaaaaatat aactggattt aggcctacct tctggaatac
     4981 cgctgattgt gctcttttta tcctacttta aagaagcttt catgattaga tttgagctat
     5041 atcagttata ccgattatac cttataatac acattcagtt agtaaacatt tattgatgcc
     5101 tgttgtttgc ccagccactg tgatggatat tgaataataa aaagatgact aggacggggc
     5161 cctgaccctt gagctgtgct tggtcttgta gaggttgtgt tttttttcct caggacctgt
     5221 cactttggca gaaggaaatc tgcctaattt ttcttgaaag ctaaattttc tttgtaagtt
     5281 tttacaaatt gtttaatacc tagttgtatt ttttacctta agccacattg agttttgctt
     5341 gatttgtctg tcttttaaac actgtcaaat gctttccctt ttgttaaaat tattttaatt
     5401 tcactttttt tgtgcccttg tcaatttaag actaagactt tgaaggtaaa acaaacaaac
     5461 aaacatcagt cttagtctct tgctagttga aatcaaataa aagaaaatat atacccagtt
     5521 ggtttctcta cctcttaaaa gcttcccata tataccttta agatccttct cttttttctt
     5581 taactactaa ataggttcag catttattca gtgttagata ccctcttcgt ctgagggtgg
     5641 cgtaggttta tgttgggata taaagtaaca caagacaatc ttcactgtac ataaaatatg
     5701 tcttcatgta cagtctttac tttaaaagct gaacattcca atttgcgcct tccctcccaa
     5761 gcccctgccc accaagtatc tctttagata tctagtctgt ggacatgaac aatgaatact
     5821 tttttcttac tctgatcgaa ggcattgata cttagacata tcaaacattt cttcctttca
     5881 tatgctttac tttgctaaat ctattatatt cattgcctga attttattct tcctttctac
     5941 ctgacaacac acatccaggt ggtacttgct ggttatcctc tttcttgtta gccttgtttt
     6001 ttgttttttt tttttttttt tgagagggag tctcgctctg ttgcccaacc tggagtgcag
     6061 tggtgcgatc ttggttcact gcaagctccg cctcccgggt tcacgccatg cttctgcctc
     6121 agcctcccaa gtagctggga ctacaggcgc ccaccaccac actcggctaa ttttttgtat
     6181 ttttagtaga gacggggttt caccgtgttg gccaggatgg tctcgatctc ctgacctcgt
     6241 gatctgtcca cctcggcttc ccaaagtgct gggattacag gcatgagcca ccgcgcccag
     6301 cctagccata tttttatctg catatatcag aatgtttctc tcctttgaac ttattaacaa
     6361 aaaaggaaca tgcttttcat acctagagtc ctaatttctt catcatgaag gttgctattc
     6421 aaattgatca atcattttaa ttttacaaat ggctcaaaaa ttctgttcag taaatgtctt
     6481 tgtgactggc aaatggcata aattatgttt aagattatga acttttctga cagttgcagc
     6541 caatgttttc cctacgatac cagatttcca tcttggggca tattggattg ttgtatttaa
     6601 gacagtcaga ataatgatag tgtgtggtct ccagaggtag tcagaatcct gctattgagt
     6661 tctttttata tcttcctttt caatttttta ttaccatttt gtttgtttag actacacttt
     6721 gtagggattg aggggcaaat tatctcttgg agtggaattc ctgtgttttg agccttacaa
     6781 ccaggaaata tgagctatac tagatagcct catgatagca tttacgataa gaacttatct
     6841 cgtgtgttca tgtaattttt tgagtaggaa ctgttttatc ttgaatattg tagctaacta
     6901 tatatagcag aactgcctca gtctttttaa gaaggaaata aataatatat gtgtatgaat
     6961 ttatatatac atatacactc atagacaaac ttaacagttg gggtcattct aacagttaaa
     7021 acaattgttc cattgtttaa atctcagatc ctggtaaaat gttcttaatt tgtctgtgta
     7081 cattttcctt tcatggacag accattggag tacattaatt ttcttaatct gccatttggc
     7141 agttcattta atataccatt ttttggcaac ttggtaacta agaatcacag ccaaaatttg
     7201 ttaacatcaa agaaagctct gccatatacc ccgttactaa attattatac atccagcaga
     7261 ttctgggatg tactaactta gggttaactt tgttgttgtt gataatacta gattgctccc
     7321 tctttaattc ttcttctggt gcaaggttgc tgcttaagtt accctgggaa atactactac
     7381 aaggtcaaat tttctagtat cttacagcct gattgaaggt gattcagatc tttgctcaat
     7441 ataaatggat tttccaagat tctctgggcc atccttgacc cacaggtgat ctcgctggag
     7501 tatattaact taacttcagt gccagttggt ttggtgccat gagatccata atgaatccag
     7561 aacttcacca ttgcttagat ataagagtcc cttggaagaa taatgccact gatgatgggg
     7621 gtcagaaggt gtattaactc aacatagagg gcttttagat ttttcttcaa aaaaatttcg
     7681 agaaaagtat tcttttaccc tccaaacagt taacagctct tagtttctcc aaatatgctc
     7741 tttgatttac ttatttttaa ttaaagatgg taatttattg aacaatgaaa tccgtaatat
     7801 attgatttaa ggacaaaagt gaagttttag aattataaaa gtacttaaat attatatatt
     7861 ttccatttca taattgtttt cctttctctg tggctttaaa gtttttgact attttacaat
     7921 gttaatcact aggtaacttg ccatatttct ggttctatat taagttctat cctttataat
     7981 gctgttatta taaagctggt ttttagcatt tgtctgtagc aatagaaatt ttactaagtc
     8041 tctgttctcc cagtaagttt tttcttttct cagtaagtcc ctaagaaaac atttgtttgc
     8101 cactcttact attcccaatc ttggattgtt cgagctgaaa aaaaatttga tgagaaacag
     8161 gaggatcctt ttctggtgaa tataggttcc tgctttaaga atgtggaaat ccattgcttt
     8221 atataactaa tatacacaca gattaattaa aattgtgaga aataattcac acatgacaag
     8281 taggtaacat gcatgagttt tgaatttttt taaaaaccca actgtttgac aaaatataga
     8341 acccaaattg gtactttctt agaccagtgt aacctcacac ctcagttttg cttttccaac
     8401 cctgacttga aaggcatatt tgtatctttt tattagtgat agtgaagctg tgacactaac
     8461 cttttataca aaagagtaaa gaaagaaaaa ctacagcgat taagatgaga acagttctgc
     8521 agttgttgaa ctagatcaca gcattgtagg cagaataaaa aatgttcata tctgagaata
     8581 ttcctttcgc catcttttcc caaggccaga cctcctggtg gagcacagtt aaaagtaaca
     8641 ttctgggcct ttgtaatcgg agggctgtgt ctccagctgg cagcctttgt tttaatatat
     8701 aatgcaggac tgtggaaaac agttggcata gaatattttc acctaaaaaa gaaagaaaag
     8761 acatacaaaa ctggattaat tgcaaaaaga gaatacagta aaataccata taactggaca
     8821 aagctagaag aacctttaga agatttgtct gaaaacagat ttcaagagtg agcttttata
     8881 cactgctcac taatttgctt gattactacc aactcttctt aaagttaaca cgtttaaggt
     8941 atttctggac ttcctagcct tttagcaagc ttagaggaac tagccattag ctagtgatgt
     9001 aaaaatattt tggggactga tgcccttaaa ggttatgccc ttgaaagttc ttaccttttc
     9061 tctagtgata ttaaggaacg agtgggtagt gttctcaggg tgaccagctg ccctaaagtg
     9121 cctgggattg agggtttccc tggatgcggg actttccctg gatacaaaac ttttagcaga
     9181 gttttgtata tatgtggatt tttctgataa gtagcacatc agaggcctta accactgccc
     9241 aaaagcgatt ctccattgag agtacatatc ttgaacttaa gaaattcatt tgctctgatt
     9301 tttaatcttg taaagttttt gctaaactca aaacaagtcc caggcacacc agaaggagct
     9361 gaccacctta ggtgttcttg tgatttatcc ttacttccct atgttgtcat agttgcttct
     9421 aaactcagct gcactatggc tgtcaacatt tctgatactt attgggatat gtgccatcca
     9481 gtcatttagt actttgaatg gaacatgaga tttataacac aggtaatagc tgaaggtacc
     9541 agtatggtgg tgagactcac acttagtgat ccagctaagg taactgatgt tataatggaa
     9601 cagagaagag gccaactaga tagctaagtt cttctgaacc tatgtgtata tgtaagtaca
     9661 aatcatgcgt ccttatgggg ttaaacttaa tctgaaattt acatttttca tagtaaaagg
     9721 aaaccaattg ttgcagattt cttttcttgt gaggaaatac atggcctttg atgctctggc
     9781 gtctactgca tttcccagtc tgttctgctc gagaagccag aatgtgttgt taacattttt
     9841 ccgtgaatgt tgtgttaaaa tgattaaatg catcagccaa tggcaagtga aggaattggg
     9901 tgtcctgatg cagactgagc agtttctctc aattgtagcc tcatactcat aaggtgctta
     9961 ccagctagaa cattgagcac gtgaggtgag attttttttc tctgatggca ttaactttgt
    10021 aatgcaatat gatggatgca gaccctgttc ttgtttccct ctggaagtcc ttagtggctg
    10081 catccttggt gcactgtgat ggagatatta aatgtgttct ttgtgagctt tcgttctatg
    10141 attgtcaaaa gtacgatgtg gttccttttt tatttttatt aaacaatgag ctgaggcttt
    10201 attacagctg gttttcaagt taaaattgtt gaatactgat gtctttctcc cacctacacc
    10261 aaatatttta gtctatttaa agtacaaaaa aagttctgct taagaaaaca ttgcttacat
    10321 gtcctgtgat ttctggtcaa tttttatata tatttgtgtg catcatctgt atgtgctttc
    10381 actttttacc ttgtttgctc ttacctgtgt taacagccct gtcaccgttg aaaggtggac
    10441 agttttccta gcattaaaag aaagccattt gagttgttta ccatgttact atgggactaa
    10501 tttttaattg ttttaatttt tatttaaact gatctttttt tatatgggat tacattttgg
    10561 tgttcactcc ctaaattata tggaaaccaa aaaaagtgat tgtatttcac atatggacat
    10621 atgattttaa gagtacatgt ttttgttttt ttaatttggt gttacataaa agattatcct
    10681 atccccccgg gagataaatt tatactactt aatataaccc cacaacaggc gcacaccaca
    10741 cactgcacag tgctatttat acatttttat ttatttcaga gtttgcctat gctacattag
    10801 cgctctaata cataagatct atgctgtaaa caaaaacatc ttcaaagttg aaatttgctg
    10861 aaatatactt ttaacaaaat aacattttta aggctccatt gaaaaatact agataagata
    10921 taatctcata taatcagtat gaataatttt aaaaatgaga aatatttagg tcagccacac
    10981 ttcctttgtg ccttgcaaga attcagttct gtggatgaat cagtactggt tagcagactg
    11041 ttttctgcaa accattttaa acatgcttta gtatgcaaca aaaagggacc tcaaatgcta
    11101 aaatacacta ttttacgtgg cattgaatag ccttgggact ggtgtagttt tatcaacact
    11161 tttttattag gaagaaaccc aagaaaattt actgtaattg ctaccacctg ccactgtata
    11221 aataatctaa aagggacttc ccaacattga acaacaacat tgagggctga ctcgagatcc
    11281 ttctacattg tcacctcagc ctggctttgc ctgtcactgc ttagcttgaa gtagtgacac
    11341 tgttctgtat caggagattt ttataatggc cctagcatcc ataattccac atgttcatca
    11401 aatggctgaa gagtatgaga gaagtattaa ggtctatgtt tgggctgtct ccccacttgg
    11461 catattctgt ttttccctct tcaaaataga ttgaaagcct cttagtgcag gaagcaggca
    11521 tcagtatcaa actgatgtca tccaatgtaa ttattttaag ctccaggttt gtctaagttt
    11581 gggtgaagaa tgttcaggaa catgtttgca acatacagtt atccagctta ccctttgaca
    11641 gattcaccct tctcatcaaa atagtaagcc caacctaaaa attataagtt tacaaataaa
    11701 ggaatagaaa aacccaaaaa gctaatttac acataaaaat tatcttttgc tgcaataaat
    11761 aggtatggaa atatttgtag aattggttta actgattttg taaaacaaat gtcatgctat
    11821 tttgccatag tgagacatgc agtaattctt aaaatcacat taatagaagg caagaacatt
    11881 gaatcagact tagcagataa cagattcagt gataaatgaa caatagacta agcatactta
    11941 ggaagctaca tgagaacaga atgtattact gtgctcccgt ccaaactgca tgactttatt
    12001 ggttatagaa taaatggaat ttgagatggg gatttgccag tttttacagt ctgtcttcaa
    12061 tagttttgtt ggctgcctct gcacctttct aaatgttatg tgaaaataaa attatttaag
    12121 ttctaaagta gtttaggaaa gagatgtgat gacaggaaaa agaagttaac ttctgaacag
    12181 tttggtccag gaagaagatg ggcagaatac agtaagccca gggttgaaga atacattcaa
    12241 tttggagaga tggagaagac ctttgaagaa ggtcaaaatg agatcttgga acagaactct
    12301 cacctgtgtg tctggatata catgaaaact ggacggtgtt attgagctac tgcttatatg
    12361 gtgagcagaa aattgataac cacaagcctg gtaggttctg ctatgaagcc cacatataat
    12421 cacaaggcct agatagcttg gagttaaaag ccaaggatag ctgtatagtt tgggttccat
    12481 agtttgcagt gagattgtgc ttctgagcag tcatttgggg gcagtggttc tgagattaca
    12541 agccataacc cagccaagaa cgggctacct gtggaatgag gatgaggaag ttgctacata
    12601 taaaccctag tgtgtgtgtg tgtattaagt gaaacttagt taactttttt gctcacagcc
    12661 aaagatgatt catctagaga agccattgga attttagcag agttttgtat atatgtggat
    12721 ttttctaata agtagcaaat cagaggcctt aaccactgcc caacagcgat tctccattga
    12781 gagtacgtat cttgaactta agaaattcat ttgctctgat tttaaatctt gtaaagtttt
    12841 tcttcatgag aggtcttgcc tctaaactat attgtggcag tatttgatca aactacataa
    12901 gtaccatgta aataagattt taatacaaat gatgactcac ttctaaatgg tttgccattt
    12961 agaaatgtgc tgctgtgaga aaaacgaatt tttttttttt ttttttggag acagagtctt
    13021 gctctgttgc ccaggctggg gtgcagtggg gcgatctcgg ctcactgcag cctcgcctcc
    13081 tgggttcaag tgattctcct gccttagcct cctgagtagc tgggattaca ggcacacacc
    13141 accacgccca actacttttt gtatttttag tggagacagg gtttcaccat gtttgccagg
    13201 ctggtcttga actcctgacc tcagatgatt tgcctgcctc ggcctcccaa agtgctggaa
    13261 ttacaggcgt gagccatcat gcctggctga aaagtgaaaa tttaagccag cttaccacct
    13321 ggaataaaaa tgttttatag gaatgtctag gttgctcttt tatattgaaa aaaaacttat
    13381 tagtgtctgt tttacccaag aaccacaagc tacttcattt caacttttaa atcatgaata
    13441 ataacgtgtt atcaccacat ttaaaaatgt acatcgtcaa tcacaaacac atattctaag
    13501 gaattgaatt ttatagagat aattgaatgc tttcatctgt aaaagaatta gtggcctgca
    13561 aaccactgtg gattcttgct atgctttgaa gttgtcagtg ggggaatttg ctgctgcaag
    13621 ttacttagac ttgtaggcaa agggaaattc aaatttttaa ttctaaaatg aaaaccactg
    13681 acaaaatttt atactctgaa agtttggttg ttagcttagt cattattttc ctgttcttta
    13741 tcatttcgga attcagatgc ttaaatttaa catacaaatt atttgttggt aaaacataaa
    13801 acataaaaag ctacatttgg taaactaaat tttaggattc aaagtctcta acaatttcta
    13861 tgtgacatgt catacggtgc agtttttatt tgccaaagtg tctacttcat actgcctatg
    13921 cactgcttcc cgtttttaat ctctctaccc caacccccct ataattaaat aaacccctag
    13981 aaaactgcct tcttttagaa tacctaattg attactttaa atattttttc agaatcaaaa
    14041 ttacaaaagg gagagatacc taagaatctg gcttgtttat attctttaaa agatcgcatt
    14101 tgattgaagg tgggtgcata ttttttatat ccactctttc cccatttgta tgtgaccatt
    14161 gtaaaagtgg atgtgctttt ttttttttgc tgaggtctag agacaatgtt ttagagatac
    14221 agaatgaaac atttatgggt aaaatacaat gggtaagact tgcttcaaaa tagtatgtga
    14281 cagaggaagt agatggaggt atgaatgaat aggacattga tggttgtttg ttgggattgg
    14341 gtaagggagc tttgttgtat tctatttcct tttagataag tttgaaattc cttgtagtga
    14401 agaaattaaa cgtctccatc aggtgcattg ccacgtcttc tctaggaagc ctccttaaca
    14461 tcctctggtg gctcctgaac tttttctgtt ctcattcaca gggaagctca tggggctgcc
    14521 tggagacttg aggttacatc ttgcctagta ttaccaaaat tgtgatactt ttctccaccc
    14581 cataatagca cagtctttgg tctcaacttg aactaaagtc tttttttttt tttttttttt
    14641 tttttttagt atttattgat cattcttggg tgtttctcgg agagggggat gtggcagggt
    14701 cataggacaa tagtggaggg aaggtcagca gataaacatg tgaacaaggg tctctggttt
    14761 tcctaggcag aggaccctgc ggccttctgc agtgtttgtg tccctgggta cttgagatta
    14821 aggagtggtg atgactctta acgagcatgc tgccttcaag catctgttta acaaagcaca
    14881 tcttgcaccg cccttaatcc atttaaccct gagtggacac agcacatgtt tcagagagca
    14941 cggggttggg ggtaaggtta tagattaaca gcatcccaag gcagaagaat ttttcctagt
    15001 acagaacaaa atggagtctc ctatgtctac ttctttctac acagacacag caacaatctg
    15061 atctctcttt cctttcccca catttccccc ttttctattc gacaaaaccg ccatcgtcat
    15121 catggcccgc tctcaatgag ctgttgggta cacctcccag acagggtggc ggccgggcag
    15181 aggggctcct cacttcccag acggggcggc tgggcagagg cgccccccca cctcccggac
    15241 ggggtggatg ctggccgggg gctgcccccc acctcccgaa cggggcagct ggccgggcgg
    15301 gggttgcccc ccacctcccg gacggggcgg ctggccgagc aggggctgcc ccccacctcc
    15361 ctcccagacg gggcggctgc tgggcggaga cgctccttac ttcccggacg gggtggttgc
    15421 tgggcggagg ggctcctcac ttctcagacg gggcggccgg gcagagacgc tcctcacctc
    15481 ccagacgggg tggcggtcgg gcagagacac tcctcacatc ccagacgggg cggcggggca
    15541 gaggcgctcc ccacatctca gacgatgggc ggccgggaag aggcgctcct cacttcccag
    15601 actgggcggc cgggctgagg ggctcctcac atcccagacg atgggcagcc aggcagagat
    15661 gctcctcact tcccagacgg ggtggcggcc gggcagaggc tgcaatctcc gcactttggg
    15721 aggccaaggc aggcggctgg gaggtggagg ttgtagcgag ccgagatcgt gccactgcac
    15781 tccagcctgg gcaacattga gcactgagtg agcgagactc catctgcaat cccagcacct
    15841 cgggaggccc aggcgggcag atcatgcgcg gtcaggagct ggagaccagc ctggccaaca
    15901 cggcgaaacc ccgtctccac caaaaaatac aaaaaccagt caggcgtggc ggcgcgcgtc
    15961 tgcaatccca ggcactcggc aggctgaggc aggagaatca ggcagggagg ttgcagtgag
    16021 ccgagatggc ggcagtacag tccagccttg gctcggcatc agagggagac ggtggaaagt
    16081 gggagaccgt agaaagtggg agacgggggg agacgggaga gggagaggga tgtgcttttt
    16141 ttctaaccgt tattgccacc aagtaataat gtcttaattc acaatttaca tagtgattgg
    16201 ctggagagag gtattgagca taaatttttt tttaagattc aactgggaaa tggatgattt
    16261 acatgatttt agtctcttta gttgtctggg tatttcttga ctgggaatag caatatctta
    16321 aaggccattt ttaacaagaa tgctaaggat ggaacacttg aaggaagcag tcctgtacag
    16381 tcaaatactt cagttacctt ggataataga atgaaaactc aattgcctac tttgaacaaa
    16441 tttttttttt ggattttaat ggctggacag aataacattc tgctaatttt aatccttggt
    16501 catttccgat gtaatggaaa atgcagtttg actcagaatc ggaggcctgg ggtttggacc
    16561 ctgattgtgc caatttatgt gactttagat aaatcttttc atcagtctac cttaaagttc
    16621 ttcatttcct ccagttccct aaaatgagga agttagtttt tagggtggtt atgagaacta
    16681 aatgagagca cttgagagat cattcagcct gaagtgggta ctcagtatta gatggctaaa
    16741 tctgcacagt ctagaatacc aggcaaaggt tactctgaag gtctttgcta ataacaaatc
    16801 tttctctaag aaagtttgta aatgtgatgt taaactcaga aatgtcacat agaacatatt
    16861 ggagcaatta ttgccgcaaa agtaactcgt agcaaccaca aaaacccagt ggtgtgcagc
    16921 aataaacagt ttatgaatta gataagtgat ttcggctaga tgtctctgga gcagttgtag
    16981 tctttcctcg ttcatgaggg agttggcctc acctggaagg acttggcatt tttccacatg
    17041 cctcctatcc tccattaaac aagcatgttt ttgtggaggt tgtagaaggc aacaacagcc
    17101 aagcccaatc ccataactcc ctttcatgtc tgcatgcttc atgctaacta gcattcacca
    17161 gaaacaagcc acatggctaa acccagtgtg gaaaggcact acagagttat tagaccaagg
    17221 gagagaacat aggaggggtg aagaattgga gccttaaatg cagtcaatct accacaccct
    17281 tgctttgtat ttaacaggtt actgtactgg tttgccagca aacaatggaa aatgtggaga
    17341 agctgaagaa tgctcaagct gggacttaat agagtggcct atttggtttg aaatgtttta
    17401 acttacagag cattgagtag aagcctaatc taatatacat aaggaagaca aaagcaaagg
    17461 attgtgtttt ctatctaaag gttaatcatt gtggttgctc ctggccatta tcacatgact
    17521 ggaagttaac actctccaaa cgctgagcct atcctgtaca gcactagaaa gtagaaagaa
    17581 tcactcaatt cagggaaacc gttttctctt aatgtgaaca tttacattaa tgccatttcc
    17641 aaaacctttc tgggacttct taaatgcaaa gatgctatct gctttacttc atgctgcctg
    17701 tttttaggag cttggagtgc tttaggaagc ttcccaatac tggtttagca gtaatttggt
    17761 tgactgatca aggcatgttt taactttgac actgaaattt taaaaagaca acagttatct
    17821 tgcccggaga gtcaagtttc tgcttccaag gaggtcagga attgttctct ttggtgatgt
    17881 ggctgtgctt ggtagccctt gaaagtggag tcgacagcag tcctcagctt ttgtgtgcct
    17941 gtcttagtct gttttgtgtt actataacag gatagctgag gcagggtcac ttatgaagga
    18001 tgctcacagt tctacaggct gggaagttca agggcatggc cctggctttt ggcaagggct
    18061 ttgctgctgc ttcatagctt gatggagaag gtcagagggg aagcagacgt gcaaacaacc
    18121 cacttgttca caacaaccaa acaagtctct ttttaacaac ccactcctgg ggactaatct
    18181 agtcttgaga gagtgagaac tcattgcaag agcagcacca agccattcat gaagcatctg
    18241 cctcagtgaa ccaaacatct cccactaggc cccagctctc aacaccacca caatgaagat
    18301 aaaatctcat catacatttg agggacagtt tgggagacag accatagcag tgctcagtat
    18361 ttctacccaa atgttcaggt aacttaatat atttttcctt gaatatatgt ttaaatgggc
    18421 ttcccttccc cacgctcatc ttgaatggtc ccacaacaac ttttgattat cacgttcctg
    18481 taaatacaca aaaatatttt gtggtctttt actggcagcc cagtggatgg gactttaaaa
    18541 aatcacccag attccaacaa ccagagaaaa cgactggtgt atattttttc cagtctttat
    18601 ttgtatgtct gtgtatattc aatggaaaat gtttgaagct tcactcacag cacattccat
    18661 tagagaaagc tactaaaatc ataaggaaaa tctaaaatgc agtaagccag tcagcaagcc
    18721 ataatgggca tatgaaaaca aagttttttg ccatgatttg tggaccacag aagatctgtg
    18781 ttattagtct atttaagttt ggtgtttgaa attaaaaatg ttcgacatac tttttatgtt
    18841 ttttttaaat atactgtcta tatttaaaat tgagtatact gtactttagt gtgtttggaa
    18901 gcagatatcc ccaaataaaa gtatacagta gaaccaaaga attttattga tcagctagaa
    18961 tttagttttc aggtgtaata actgtcaacc taaataacag aggctttcta aaagaaaatg
    19021 atgtttattt gggaataggg cattgtgaag gcaatatgca tgccatagta aactgtgtgt
    19081 attcaggaag gtaaaggaag acaggttttt aaaggacaga taaagattat ataattgtct
    19141 tgaaataatt attcttggct acaaggatta ataacaagga tgctgccagt tcgggtttgg
    19201 acaatcggct tctaggcaga tgtcccaaaa gtattttctg tgtaaggttg cgaatagtgt
    19261 ttgtgcaagc tggcgtggtt tcttctgggt ctttgaggta gtgcgtaaaa tccctctctt
    19321 catggacttc cctggctcca tttgtcaggg cttttggaaa catgactctt gattctgaca
    19381 gctttcacct ttccctctct tgatgaagat gtttttccga aagtatctat gatgaatcat
    19441 cttgtagtta ggctttgatt gtcccttggt gacagaatag acctttcccg ggttattggt
    19501 ctggtcctgc atcctgcatt ggcaggagtg attggcaact aaaagtcagt gttaaaaccc
    19561 ttttagccac ctttgagggc agggaggctt taagggagtg gcacttaggc taagtccacc
    19621 tggagtctat tattaagtcc aatttttttt ccttagtcct ttgttgtccc ctcaaagtgc
    19681 tgggctagca ttattctgtt aggaattgta cttctttctg cagaaaattt ggcaaataac
    19741 agatacaaag tttaaaaagg aaatacacaa aattaatagt aatgtgacaa tcccagtttg
    19801 cataatggtt ttgagccctg aacctaggct tacaggcaac caattgaata aatcaaattg
    19861 taatacaatt cttgctctga tgtcttagga aaaatgtcta cagcctgaaa tcatcaactt
    19921 tttgtcctgg tttgcagttt gaatgtctct agctatggca ttggttggta tggtgaactt
    19981 ttgtgtgacc catacatcag catgagactt gctcctttaa aaattaatca catcttagct
    20041 tataggcctc agagcatggg agtagttttt tttcttagag agtcatagcc aaatattgaa
    20101 ggaaattagg aggattcagg agcaaatcca gtctgcaggt ggataacagg agtttcaaaa
    20161 cggtacagag ctgtgatcta ataacaggta catatagctt tcttcagaaa cttaaagtta
    20221 ccctgatttt taccaaagat gttcagaata aaacagattt gtaaacttta tcagattttg
    20281 tctgcaagaa tagtagtatg gtcacagtaa tctcagattt aaaaacctcc ttgaggctaa
    20341 gaagctaagt caaggtagac tttagatttt acctatagtt ttaaggttcc tgggcctgcc
    20401 aggaaatgat aatttttaat tcagtgtaat gctgagaacc attgaagcca ggcattctac
    20461 acattctcaa atatgacatt ttaatcaaag ccttggtaat acaaccagtg tttccaattg
    20521 tatcctgtta taacgagagc cgatttttat tgaacttagg caaatcatat tgccttaaga
    20581 gtactcacaa ataggctggg cacagtggct catgcctgta atcccagctc tttgggaggc
    20641 caagacaggt ggaacacctg aggtcaggag tttgaaacca gcctggccaa catagtgaaa
    20701 cctccccccg gccaccgtct ctactaaaaa atacaaaaat tagctgggtg tggtggtgca
    20761 tgcctgtagt cccagctact tgggaggctg agacagaatt gcttgaaccc tggaggcaga
    20821 agttgcactg aaacaagatc gtgccactgc attccagctg gggcaacaga gcgagactcc
    20881 gtctcaaaaa caaaaacaaa tgaatactca aaatagtttc caaattggag ggatcaagaa
    20941 gaaaggaaaa gcaaatattt ctacctttgt tcacaaaagt attccaaatt gctgtaaact
    21001 atagatagca tgagagaatt tctttaaata tggaaaacaa aacatttaag taaaaaaaca
    21061 ataatgcttc aaataaaagt cacagacaca tcttcagtta cttagtctca tgtaactttt
    21121 tttgttgtgg ttgatcttaa ttagtagtta catggactca tcagtttctt gaagttctga
    21181 aaaaatattt agtccattgg tattaaagtg attagtaacc tgtatttaaa agtgtgttag
    21241 catcttttcc atgaatctga ttgcaaatgc ttttagagaa aaagcaataa ctgggaatta
    21301 caaaaactta gaataaccat gattaaaaat ctgatgagag tttaccataa ccagaaatag
    21361 acaaagagtt ttggttattt ttgtggcaaa cagcataatc agaattatga ctgatgacat
    21421 atttctaacg gcatcgtaca attttggaac actcatatca ataacatact cataaatgta
    21481 actgtgtcta gtattacatc attagacaat gcttttcata caatttaata catcaaagaa
    21541 gcctaattag ctaacatctc taccagatgg catacacatg ctctgaggct ttccagaggc
    21601 ccaagtggaa aactcaaagg taattttaag tcaaaaacac ttaatttaga acttgagcct
    21661 agagaagcct gtcaaagatg tcaaaagttc gaaacaggat cacaggtcac tataaaatat
    21721 ttaacaagaa tgataatcaa aagacttaag aagcaatgca gaaagttaca tacatttaaa
    21781 aaccatcttt tcaaagcttc atttttccca agcaaaaaaa aaacttaaac acaagaattt
    21841 atcttgatag aacataaaat ttttcttagg ccagttgcca aaatggtaaa gaaaaatctc
    21901 ttgcagtgtg actgccttta cttatgggaa gcctatttgg atatactgaa agttgaatct
    21961 gatgaaaagg tacttgaatt taatcagaca caggaagagt atttccaagg ttatgagtgt
    22021 acgccttata gaggaatgta aataagaaag ctagtatgtt gaacagaata catggctctt
    22081 ggaaaaatta cgagaaattt cctgcttgcg tggaacaatt caaacatgag aagagccaag
    22141 aattcagaat caagttatac tggaggaaaa cattgctttt ctaggccttc tacagaacat
    22201 ttcagtatca agttataaca gcaagagtta gaaccagagg aaaaaagtta caggagctaa
    22261 tgaaaaagtt aagagttatc acccctgcca aacaaaaaga tgtaccttct taaggggaga
    22321 aagagctaaa ggcaatgatg tgtgacctac aaataaggtg cagcaagata cagcaaaggt
    22381 tgaacttgtg agatataaat caggatcttc aagaagaaaa ctctacctca agaaatgaaa
    22441 tgaccatctt aaatgaaaaa agacagcctt tctaacctga atctagggga aattaaacgg
    22501 atctcagaag gaaatatggc agaaatttaa actgtggttt agaagatggc tgattttaga
    22561 attaaaaatt aaaacctctt tcaattttat taagaccaga tccttaaaaa gaaccttgtt
    22621 ctaacattgg ggaccaaatt ttgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
    22681 gtgtgtatag tgcatgtata gcatttacac tatcgtgtat atacaaatat atagcatatg
    22741 tatagaatat actgtattat tgtacatata catatgtaca agtatatatg taagctcaat
    22801 gtcttatgat ttcattctga cctattgcca acttcattac acacaactcc tttcataaat
    22861 gtatccttca tgaacatttc atgatctgca cagaccttca gtgacatgct taaactttct
    22921 gctttgtttt atacttcccc ttaaacaact ggtcatcctg ctttaggata aaaagttact
    22981 atgcaagact catacagaat tattctgtta attttgtaac cttccttacc aaaggtacat
    23041 tctcacaccc attaacttcc ttcatatttc tctcctcctc ctacttagtg gttcctttct
    23101 gtcttgtttc catatttgaa acaacctcta ataaactctg aatttaaaca acttttttcc
    23161 caataaaaag caatttttat gccttataac ttttctcatc aaaacatctt tttttgggta
    23221 cactttgtat atggaattgt gtattttcaa attttaactt attaacctta atttttagtg
    23281 aaaacctagg aagcaaaatt ttgaagtgtt atatcagcat tttataaatg agaaccatat
    23341 tataattttt agaaacatgt ttccttataa ctttgtatat taataggccc aaatatattt
    23401 agtctttcta taatttagga agccaagaac aaactaatat tttcagcagt ttattgtttt
    23461 tttttggaaa tgatccagac atttactgaa gattaattta taagatttca aattacatga
    23521 aaagttcatt aacatcctat ttttaaaaac attcttttgg tttatttttt agagacaatg
    23581 tcttgctgtg ttacccaggc tggagttcag tggctgttca caggcacaat tgtagcacac
    23641 tgcagcctca aactccaact cacacaatcc tcctgcctcc gtttcctgag tagctggaac
    23701 tatagatgca tacctgcata ccaccatgtc tcacccttgc ttatcccgtt tataatccat
    23761 ccaattcttt tttttttttt tttttttgag acggagtctc gctctgtcac ccaggctgga
    23821 gtgcagtggc gtgatctcgg ctcactgcaa gctccgcctt ctgggttcat gccattctcc
    23881 tgcctcagcc tcccgagtag ctgggactac aggcgcccgc caccgcgccc agccaatttt
    23941 ttgtattttt agtagagacg aggtttcacc gtgatctcga tctcctgacc tcgtgatctg
    24001 cccgccttgg cctcccaaag tgctaggatt acaggcgtga gccactgcac ctggccccca
    24061 attcattttt aacaattatt cctagattac ttataaaaac tgagatatta gacatagcta
    24121 gtcatttcaa gttattttcc tgttaaccat ttttattacc tgtgagtatc atgtgttcaa
    24181 ttaagaacca taaaaatgaa atatgtaggt attttgccag taactcagag gacacagctg
    24241 aagtcaataa tacaaaatta gttcaactta cagttataca aagatcattc tgtttttaag
    24301 ttgagtttat agttttatga ccttaaaaag tctaacagag acaaatataa aactgagtag
    24361 taaattcagg caaaaatttt aaagacactt atttttgatt taccaattat tttaaaacca
    24421 gcttatcaga tgtttaagtt atattaacta aaaggcactt gtgttaatta ctatatattt
    24481 tgtattagca ctcatttatt tgatgaatag aattccttaa gggatttgtg gccaactgcc
    24541 agattttacc acgtagacac aacatacaac atatatatac atatgtgtaa acacacctaa
    24601 acatacacat acacaaacat agctttcatt ttagaatttt agtcatacga tagtaataca
    24661 ggcttgctgg tttataaaag acagttattg gattcaaatt atatttctga gaaagtggga
    24721 cctgctcagc tgggtaaaca tgcagaatag gtaatcttat gaaagctgtg aaccaaaagt
    24781 tttggtaaat agcagtttgg atttttaaaa aacctcttac cccacctccc caaccccttt
    24841 tttccctttt ttcagtttca aatgagttta atgttaatat ttaaatgctt acatttttag
    24901 ctaggactgg ctgaattgta taagaaaaaa caatctccag gtggccttga atttttagta
    24961 acaaatcttt tgtttgccat tctggttttt ttgactagtc agtgcaggca gggaagcatt
    25021 ttagcagttg tggatgaggg gtttttgttt tgttctttta gcctttgcat agcaggcaag
    25081 caatttttat gctataccag agatacctta tattattgcc ctgagctcaa gattttgacc
    25141 tgtttgagag cctaattttt atacgtattt atctagttct tttaggctat taatccttta
    25201 attaactgtt ccatcaccct aagcagttat taggcaaacc taaatttaca ttaaaaggga
    25261 tacttcttaa ttctaggtgt tggttgccag ggaactatta taatttataa agccattaat
    25321 ttaaggccct ttaagacctt tttttttctt tttgttcttg gctggaatgc cgtaaggagt
    25381 gagtttcatc tcaacactgg cagaaacagc agatttaaag taggcagaaa aaaaattaga
    25441 gagcttagaa gactctacat atcaactcta tagctgcagt ctcttggtac taagaataaa
    25501 aaagcttggg gagtttagac aaagcataga caatctctat gatggtcatt gatccaaaaa
    25561 catgcatgag gaaaagccac atagctgacc tgaagtccca gaaaagcagg catgccttaa
    25621 tgtttgagaa tttccatttt gtttcttctc aatctcttaa gagcaaagaa aattctgtaa
    25681 atcctgacag ataagtcagg tgtttggacc agtgttttaa ctggtggcga ttgccctagt
    25741 ggctttaaaa gagccatcct gtgcccaaaa tttagaatgt ttatttttgc tcttgggaga
    25801 tgttcagaaa caggggaaaa gagccaaatc atttacagat gcatgtaacc atatcgaaac
    25861 gaaaccaaaa tcagtgttcc caaaagtgtt aacccagtca tgcagattaa aaaataatat
    25921 aaacacagaa gaacccaaag taaatttacc agaaaaggca tgcctcagaa tccagagtac
    25981 tcagccaggc gcagtggccc atgcctgtaa tcccagcact ttgggaggcc aaggcaggag
    26041 gatcgcttga gcccatgagt tcaagaccag cctcagcagt atagtgagac actgtctcta
    26101 aaaaaaaatt gtttttaaat ccagagtact caaaccagag ggacacttgt ctttatatca
    26161 aaaaggactt gccaggaaag acaaaaagtc ttttgtcatc ccaggaggga tgtaaagtcc
    26221 tttattaaag tggtcttaga accaagacaa atccaaagtc aagtcaaaaa gcctctgcca
    26281 aaagtgggag gctctgcctg agaaaagact cactggggca gaacagacaa gctatgtaag
    26341 cggagagccc aaagggctcc tgtgagtact gcatactgat tctgagatca ccacttctct
    26401 ctgaaatgtg tcctacttca ggttctactg ctgaacacca tttatgtcaa cacagagaga
    26461 ggctctctaa aagaaaactc tatttgggaa tacagcattg ctgtagaaat acgcatgtca
    26521 tgggccgtgc gcggtggctt atgcctgtaa tcccagcact ttgggaggct gaggtgggcc
    26581 gatcacgagg tcaggagttt gagaccagcc tggccaacat agtgaaaccc cctctctact
    26641 aaaaatacaa aaaattagat gggtgtattg gtgggtgcct atgatcccgc tacttgggag
    26701 gctgaggcag aagattggct tgaacctgag aagtggaggt tgcagtgagc ctagatgtgc
    26761 cactgcactc cagcctgggc gacagtgcaa aactacgtct ccaaaaaaaa aaaaaaaaga
    26821 cccatgtcat ggtaaactac gtgtgtattc agggaagtaa aggaagacaa agattttaaa
    26881 gaaaaatgag ggttgtataa ttgttttgaa ataattgtcg ttggttacaa agatcaatag
    26941 caagggtggt gccactctga agttggacag gcagtggcta ggcaaaagta ttttgtgggt
    27001 aacctttgtg aaaggttgca gtttttgtaa cacaagctgc tttattttcc caaaagcttt
    27061 cacagtacat agaaaatata ttggacgtgt attaaatgtg ccaaattagt cagcaatatt
    27121 acattaaaat atgtgttatt acttgttaat gttcttaata agttgttcag gcagttatac
    27181 cagactatct tttctcattt tccaatttat aagtgtatta tccaaaaatg ttagttttag
    27241 ggtgaccact gtatattttg gtatttttta aagctaccca attgtgtata atttataaaa
    27301 atcttttttt cataagacct aaaacttctg aacaatacat aggtgcaaat aaataaattc
    27361 ctttttatct caaactcact tccactgccc tccctgaaga aagccttttg ttattgttgt
    27421 cttgactaaa tgtggcatgg gagctaacat tttcaaggga agctgatctt atctccgggc
    27481 tctagaagcc aagacatgag gtatgtgttt accgtctctt aggtgactct ccagaacttt
    27541 cattctcaac ctcctccctc actgccagtt cctcctcagc ttcttagcca agtggtagag
    27601 gaaaaatggt attttatgtc aggactaagc catgtgctct gagccctggg taagtctgca
    27661 aggcttctct agaactcata cataggtcaa ttattcctcc tctgaaaact taaactctgg
    27721 caccactagc tttttcctac agcatacatg ggctcagtaa atcctctgtt aagacaacag
    27781 gaaaattaag acaatgtcct tgcaagcccc ataactactt tctatccctg ctattcacag
    27841 ccaagtgtgt cgagaccagt tcacacaaac cttgttgatt ttcggtttca ccccctcctt
    27901 actaaatcac ccctccattt gctgcagttg cccttgcgtg ctgtactcag acttggagga
    27961 agtgatgtct tattcaaggc cagtttttgt actagtggtt aaataaatgg tttccaaatt
    28021 ggagtcagaa ggagagcttc taaaatgtag gttccctggc ctcaattgtg agattctgct
    28081 ttagcaggtc tggaattgga gcactgggat ctgcattttc agaaaaccca aaatgattat
    28141 cagccaggac ttaaacctct gctttagacc acattccctg tgggctttca gattttctat
    28201 caatgttctt ccctcttccc agctcccaca cattaaaact cagatcatgc agaaaagaag
    28261 ttacagttcc ttcatttcac atcaatttct catgcatccc atctggtttt gggaaggtgt
    28321 gggacgaggt ggatggcctt aaacttgcca atcaaagata acgttctctt tcgattcaaa
    28381 tagcctatct caggcttaaa accatctctt tggataaatg ctcagctttt caaaggttct
    28441 tcctagcttc ttcctcatga tggcatctag tgggtgagaa cagtcatctc caggtgacac
    28501 aggaaagagt ttctctaatg tatgtgctga ggtccttgac ggtcctgctg ctggtgctca
    28561 tcctgccatc tttgctggat gtcactgagt ctactgggta atgtaagtgg gtccctggct
    28621 tttgttcact gctgtcatgc cctgctcctg accacaactc tgtcattgcc tttggtctca
    28681 aggtctctac cttaatagct tccatgtccc aactatggga ctgttaatct gctgggcttt
    28741 ggagtgggtg ggaagggatg atgttggaac tttgggatgt actgaacatc ttgctcaagc
    28801 tttgggaagc caacattttc tcagactgac tagacacctc cttccaccaa tgctgagcta
    28861 gtgctcctgt gccatactgg gtaagcctct aagtcatgag taggactttt ttgagtggct
    28921 tgcagtcttc cccaggctat gccaggaaag tagttgacta accctgctgc tccaagactc
    28981 gcatacccat cctgaagttt ccgtttattt cccaacaggg caattgcaat ctcaatcaat
    29041 ctctccctgc cctgggagtc attccactcc tgcctaatga agagactctt ctcacatcgt
    29101 attctcagtt tctcttatcc atggttagga gtaaaactca tgttcagttg tccaagcttt
    29161 gcttttagta tgtgaatgga gctcttagca tgtagaactc ccttctcatt ctcagtaaag
    29221 tctgactttg aagactactt atcatcttcc tagagatgcc aaagaataat caagataata
    29281 aaggcaggct ctgagattca cagctgagta gcaactgtgc tgttactcta gtacacaccc
    29341 tctcctttcc tgtgactgtc aggcttcagg gcttaccttt attggaaaga cagcaggggg
    29401 gcatatatga agaaaatgga atctttaata ttgtcaaagt cttgacccaa tagagacatt
    29461 cttgccccag actctcttgc ttcagtgcct ttgcctgttc tggtcctaag taccttgaat
    29521 atccttctct tgatgccctg atataaaact ctttattcct caaagccaag ttcaggttat
    29581 cacctccacc acagactttt ctttccctcc ccaaacttca ttgcctcttc tcatcactcc
    29641 ctttgtaatt tgtttatact ggtaagagag cattcatcat aattaggcct atctatgcct
    29701 acctttcttg ttaaattatg agctttgttc tgccttggat atctctctgg cttggatatc
    29761 tctctggcct ttgctctgca cttccaaatg tatccattat tcaagaccca ggtttccagc
    29821 ctgatcaaca tagcaagatc ccatctctcc aaaaaaaaaa aaaaaaaaaa attgtggggc
    29881 cgggtacagt ggctcatgcc tgtaatccca gcactttggg aggccgaggc aggtggatca
    29941 tgaggtcacg agtttgagac cagtctggcc aacatagtga aaccccatct gtactaaaaa
    30001 tgcagaaaat tagccgggtg tggtggtgtg tgcctgtaat cccagctact cgggaggctg
    30061 aggcaggaga atcgcatgaa cccgggaggc agaggttgca gtgagccgag attgcgccac
    30121 tgcactccag cctgggtgac attgcaagac tccatctcaa aaaaaaaaaa aaaaaaaatt
    30181 agctgggcat ggtggcaggc acctgtagtc ccagctactt gagaggctga ggtgggagga
    30241 ttgcttgagc ccaggaagtc gaggcttcat gagccatgtt tgtgctactg cactctagcc
    30301 tggatgacaa agtgagatcc ttttctaaaa ataaggaccc agtttatttt atttagttat
    30361 ttagttattt ttgagaccaa gtttcatcac tcaggctgga gtgcaatggc acagtcttga
    30421 ctcactgcaa cctctgcctc ctggattcaa gcaattcttc tgcctcagcc tcttgagtag
    30481 ctgggattgc aggtgcccgc caccacacct ggctaatttt tgtatttttg gtagagacag
    30541 ggtttcacta tgttggccag gctggtctca aactcctgac ctcaggtgat ccacctgcct
    30601 tggtctccca aactgctggg attacaggtg tgagtcaccc tgcctggcca gaacccagtt
    30661 taaattccat cctctctgca gagtcttcct taaccacccc tattgaaagt tacccctgct
    30721 tcctacaaga agtggtactt ggatgttcat gagatacctg tgcaaggctc ctgtgggggt
    30781 cctggggaga cagtgacatg gacactcatg aaaggaacct tggaatagcg agtgtgtgtg
    30841 ctataaaatg tgctttagat ttgattacca ccacttaagt tatgagctct gatatggttt
    30901 gggtctccat ccccacccaa atctcatctt gaattgtaat ccctacatgt tgagggaagg
    30961 aagtaattgt attatggggg tggttctccc atgctgttct catgatagtg aattctcaca
    31021 ggatctgatg gttttataaa tggtagtttt tcctgtactt tcacacactc acactctctt
    31081 ctgccacctt gtgaagaagg tgcctgcttc cccttctgcc ataattgtaa gtttcctgag
    31141 gcctccccag ctgtattagt ctgatctcac gcggctaata aagagatacc ggagactggg
    31201 taatttataa aagaggttta attgactcac agttttacat ggctggggag gcctcacaat
    31261 tatggcagaa ggtgaagggg gagcaagaca catcttacat ggcatcaggc gagagagctt
    31321 gtgtagggga actccccttt ataaaaccat cagatctcgt gagacttatt cactattaca
    31381 agagcagcac gggaaagacc cacccccatg attcagttac ctctcactgg gtccctcaca
    31441 taatatgggg aattatggga gctccaattc aagatgagat ttgggtgggg acacagccaa
    31501 actatatcac cagccatgtg gaactgttga gtcaattaaa cctctttcct ttataaatta
    31561 cccagtctca ggtatttctt tatagcagtg tgagaacaga ctaatacaag caccttgagg
    31621 tcagaggcta aaatcacttt ttcccaaaca tttccttttt atatatgcta catctttgtg
    31681 tctgcttcaa catttccagc agtgctttat atatggtagg catgcaataa atgcttcttg
    31741 atcgactgac aggtgctcag aagatctagg ttggttgatt ctcttgtgat gccatctttt
    31801 cctgagagct cattaatttt taagttgttt tccttgaaat gcatggtatg tttcctccac
    31861 cctgctcttt gcctttcata gggttccatt ttgatcagct gctctcattg tctgttttgt
    31921 gatcaaaggt tctgatgaac tttggaatat gtgtatgttt ggagtgagga tggggtctgg
    31981 aggagatgca tggttgagga ccaattcacc caacccagct tacagaagta aagcggcccc
    32041 ttaggagcac tgaagcattg ctgtggattt cagaattacc ttatttcttt ttcttttttt
    32101 tttttttttt tttgagacga ggtctcgctc tgtcgcccag gctggagtgc agtggcacaa
    32161 tctcagctca ctgcaagctc cgcctcctgg gttcacacca ttctcctccc tcagcctccc
    32221 cagcagctgg gactataggt gcacgccgcc acgcctggct aatttttgta tttttagtgg
    32281 agacagggtt tcaccgtgtt agccaggatg gtctcaatct cctgaccttg tgatccaccc
    32341 gcctcagcct cccaaagtgc tgggattaca ggcgtgagcc accgtgccca gccagcttct
    32401 ttcaaatcag agtaggcctt ccagtgtggc aggccataag atctgaagtt ttcaccctgt
    32461 tcctggaagc caagtggaca gcaactaatt tttactttct ttattgcaca tttggggctt
    32521 gggggataga gtcagatgtg tgtcagttga aactgtagct actgcattcc actccttggg
    32581 ggatcgtagt gctcatgcca acagaaaact tcgaggctaa taattactgt cttcagagta
    32641 caagacaggc acggaagttg ttttggcata agaaaaccac gatttgcatc ccacagtcta
    32701 aggaagacga tgctgaattc agaagatggt gcaaaagtgt gacagttcag ctgtggcggc
    32761 tgttgctgat gcatgggact attttattta catttccttt cttctttttt aacagagaca
    32821 ggatcttgct gtgttgccca gcctggtctt aaactcctgg gcccaagtga tcctcccacc
    32881 tcagcctccc aacgtgttgg gattacaggc atgagccacc atgcctgggc tttatttata
    32941 tttccaagtc aaatgttagt tggtcaatca gtctttttaa gcaccaattt tgtgcctagc
    33001 cttgtggaaa ctgtaggaaa aagatacttt ttatttggga ggaccttgat ttgctgtcac
    33061 aggtgccact aatgccaatt ataaggcagt gtggaatcag gtgattgaaa gcccagtctg
    33121 tagcataaac tgctgcaggg ttccagtggg ggcaattaag gtgggcaggg agggtggata
    33181 gcatttgact ttgacagcat aacctgagca gaggcacagt ggggatggtg agtgtgcagt
    33241 gggaggaggg agagaggtaa gtggtaggga agaggtggga agggggcaag gagaaggctc
    33301 aggaggtttg gggacaggga aatgacttgg ttggcgacct cttactttct tctcgtgtgt
    33361 gcaatttgga attcacttgg ttcttagtat ttctgggtca gatgacttct ttgcagtatg
    33421 agaaaccatt tcccaggctg gctacctggg ctgtggtatc ttccagtgct cctctgtgat
    33481 tgtactcaga tcagctcgtc taggcaggca ggatggcaga agccctctga cttcatgtct
    33541 gaaagagtat gtgtttcaac tctgtaatta cagcatttaa cagacgatat cagccctctt
    33601 tgggatggct tttggcaaat gggctagaag tctattgtgc atttaaatga tactgcatct
    33661 tctctttaaa aggtttctca gtgagtccac cccactctgt atccaagtat gtctcaggcc
    33721 atgaggcaaa aggaaatgag tagttctttt tggttggaga attaaaaaga aatctccacc
    33781 caagtaacag gtacatagtg ggaaaaaata acatctgcct gaaagcttca tcttcaggca
    33841 aagagagggt cagggggcgg gagcttagta atggggaaac ctcagaagat ttaaagagaa
    33901 ttacagacag acaaggctga acattggctg tcatccaaca aagctcttat aagatgggaa
    33961 tcactgcccg gttcttgagc tccgacctgg agggaagagg agtctggaag acttggcaca
    34021 ggcctgagtg cttcattgtc tttctggttc caagtcctcc tcagctcact aggaaggagg
    34081 tggggtgggg gcaggtaggc cactctgcat aagtgcacac atctacactg gctagtctac
    34141 ttcacaattc ccccacaggt tatccttatc tctacctggt tccagttcca gattggaggg
    34201 atatagaata ccatccccac ccctcacctt gcttgctctg gcctggaaaa ctgtcattcc
    34261 tttaccacca gctggcatct gccatatgct tcaaggaact gaataaagag gaaggggaaa
    34321 gaagaaacta gagaaactgg aatgcttcct atctgacccc caagtacagg gactgcctct
    34381 ttccgtaacg gcacagaacg tctccatccc tttgacctcc acctccccag agatgcccga
    34441 ggaggacagc cttgtttctg tgatctgttg ttgagaactg ctgctgagaa ttcttccttc
    34501 agcaccgcct taggcaccat tggtttttca ctaggtccgc tgtagaaaac agccaggaat
    34561 tacttagttg actaccacct gaggtgctgt ttggtgttgg taataaagaa taaaggtgga
    34621 aatgaa
//
