LOCUS       NM_032539               8421 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens SLIT and NTRK like family member 2 (SLITRK2),
            transcript variant 1, mRNA.
ACCESSION   NM_032539 XM_049884
VERSION     NM_032539.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8421)
  AUTHORS   El Chehadeh,S., Han,K.A., Kim,D., Jang,G., Bakhtiari,S., Lim,D.,
            Kim,H.Y., Kim,J., Kim,H., Wynn,J., Chung,W.K., Vitiello,G.,
            Cutcutache,I., Page,M., Gecz,J., Harper,K., Han,A.R., Kim,H.M.,
            Wessels,M., Bayat,A., Jaen,A.F., Selicorni,A., Maitz,S., de
            Brouwer,A.P.M., Silfhout,A.V., Armstrong,M., Symonds,J., Kury,S.,
            Isidor,B., Cogne,B., Nizon,M., Feger,C., Muller,J., Torti,E.,
            Grange,D.K., Willems,M., Kruer,M.C., Ko,J., Piton,A. and Um,J.W.
  TITLE     SLITRK2 variants associated with neurodevelopmental disorders
            impair excitatory synaptic function and cognition in mice
  JOURNAL   Nat Commun 13 (1), 4112 (2022)
   PUBMED   35840571
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8421)
  AUTHORS   Beaubien,F., Raja,R., Kennedy,T.E., Fournier,A.E. and Cloutier,J.F.
  TITLE     Slitrk1 is localized to excitatory synapses and promotes their
            development
  JOURNAL   Sci Rep 6, 27343 (2016)
   PUBMED   27273464
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8421)
  AUTHORS   Yim,Y.S., Kwon,Y., Nam,J., Yoon,H.I., Lee,K., Kim,D.G., Kim,E.,
            Kim,C.H. and Ko,J.
  TITLE     Slitrks control excitatory and inhibitory synapse formation with
            LAR receptor protein tyrosine phosphatases
  JOURNAL   Proc Natl Acad Sci U S A 110 (10), 4057-4062 (2013)
   PUBMED   23345436
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2410441121.
            doi: 10.1073/pnas.2410441121.. PMID: 38870062]
REFERENCE   4  (bases 1 to 8421)
  AUTHORS   Piton,A., Gauthier,J., Hamdan,F.F., Lafreniere,R.G., Yang,Y.,
            Henrion,E., Laurent,S., Noreau,A., Thibodeau,P., Karemera,L.,
            Spiegelman,D., Kuku,F., Duguay,J., Destroismaisons,L., Jolivet,P.,
            Cote,M., Lachapelle,K., Diallo,O., Raymond,A., Marineau,C.,
            Champagne,N., Xiong,L., Gaspar,C., Riviere,J.B., Tarabeux,J.,
            Cossette,P., Krebs,M.O., Rapoport,J.L., Addington,A., Delisi,L.E.,
            Mottron,L., Joober,R., Fombonne,E., Drapeau,P. and Rouleau,G.A.
  TITLE     Systematic resequencing of X-chromosome synaptic genes in autism
            spectrum disorder and schizophrenia
  JOURNAL   Mol Psychiatry 16 (8), 867-880 (2011)
   PUBMED   20479760
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 8421)
  AUTHORS   Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J.,
            Snippe,H., Hibberd,M.L. and Seielstad,M.
  TITLE     New genetic associations detected in a host response study to
            hepatitis B vaccine
  JOURNAL   Genes Immun 11 (3), 232-238 (2010)
   PUBMED   20237496
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 8421)
  AUTHORS   Smith,E.N., Bloss,C.S., Badner,J.A., Barrett,T., Belmonte,P.L.,
            Berrettini,W., Byerley,W., Coryell,W., Craig,D., Edenberg,H.J.,
            Eskin,E., Foroud,T., Gershon,E., Greenwood,T.A., Hipolito,M.,
            Koller,D.L., Lawson,W.B., Liu,C., Lohoff,F., McInnis,M.G.,
            McMahon,F.J., Mirel,D.B., Murray,S.S., Nievergelt,C.,
            Nurnberger,J., Nwulia,E.A., Paschall,J., Potash,J.B., Rice,J.,
            Schulze,T.G., Scheftner,W., Panganiban,C., Zaitlen,N., Zandi,P.P.,
            Zollner,S., Schork,N.J. and Kelsoe,J.R.
  TITLE     Genome-wide association study of bipolar disorder in European
            American and African American individuals
  JOURNAL   Mol Psychiatry 14 (8), 755-763 (2009)
   PUBMED   19488044
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   7  (bases 1 to 8421)
  AUTHORS   Aruga,J., Yokota,N. and Mikoshiba,K.
  TITLE     Human SLITRK family genes: genomic organization and expression
            profiling in normal brain and brain tumor tissue
  JOURNAL   Gene 315, 87-94 (2003)
   PUBMED   14557068
REFERENCE   8  (bases 1 to 8421)
  AUTHORS   Redolfi,E., Montagna,C., Mumm,S., Affer,M., Susani,L., Reinbold,R.,
            Hol,F., Vezzoni,P., Cimino,M. and Zucchi,I.
  TITLE     Identification of CXorf1, a novel intronless gene in Xq27.3,
            expressed in human hippocampus
  JOURNAL   DNA Cell Biol 17 (12), 1009-1016 (1998)
   PUBMED   9881668
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA239165.1, AK096278.1,
            AL109653.14, AK289732.1 and BM669862.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_032539.4.
            
            Summary: This gene encodes an integral membrane protein that
            contains two N-terminal leucine-rich repeats domains and contains
            C-terminal regions similar to neurotrophin receptors. The encoded
            protein may play a role in modulating neurite activity.
            Alternatively spliced transcript variants encoding the same protein
            have been described.[provided by RefSeq, Feb 2010].
            
            Transcript Variant: This variant (1) represents the longest
            transcript. All 9 variants encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK096278.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465404 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000335565.6/ ENSP00000334374.5
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-261               DA239165.1         1-261
            262-312             AK096278.1         259-309
            313-313             AL109653.14        147799-147799
            314-1901            AK096278.1         310-1897
            1902-3734           AK289732.1         1269-3101
            3735-4401           AL109653.14        151570-152236
            4402-4407           BM669862.1         17-22               c
            4408-8421           AL109653.14        152243-156256
FEATURES             Location/Qualifiers
     source          1..8421
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq27.3"
     gene            1..8421
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="SLIT and NTRK like family member 2"
                     /db_xref="GeneID:84631"
                     /db_xref="HGNC:HGNC:13449"
                     /db_xref="MIM:300561"
     exon            1..198
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /inference="alignment:Splign:2.1.0"
     exon            199..261
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /inference="alignment:Splign:2.1.0"
     exon            262..798
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /inference="alignment:Splign:2.1.0"
     exon            799..947
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /inference="alignment:Splign:2.1.0"
     exon            948..8421
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /inference="alignment:Splign:2.1.0"
     CDS             991..3528
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="slit and trk like gene 2; SLIT and NTRK-like
                     protein 2; slit-like 1; transmembrane protein 257"
                     /codon_start=1
                     /product="SLIT and NTRK-like protein 2 precursor"
                     /protein_id="NP_115928.1"
                     /db_xref="CCDS:CCDS14680.1"
                     /db_xref="GeneID:84631"
                     /db_xref="HGNC:HGNC:13449"
                     /db_xref="MIM:300561"
                     /translation="MLSGVWFLSVLTVAGILQTESRKTAKDICKIRCLCEEKENVLNI
                     NCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIR
                     TGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKL
                     KVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPW
                     NCTCDLLPLKAWLDTITVFVGEIVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQRGS
                     HADTHVQRLSPTMNPALNPTRAPKASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKS
                     PVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYK
                     NDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQ
                     YLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNNHFSH
                     LPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAG
                     EILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPELHTEVPLSVLILG
                     LLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDG
                     HVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATPAYTISAT
                     ELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRI
                     NKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEPDYLEVLEKQTAISQL"
     regulatory      4387..4392
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="hexamer: AATAAA"
     polyA_site      4407
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="major polyA site"
     regulatory      5250..5255
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="hexamer: ATTAAA"
     polyA_site      5278
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
     regulatory      8350..8355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
                     /note="hexamer: AATAAA"
     polyA_site      8370
                     /gene="SLITRK2"
                     /gene_synonym="CXorf1; CXorf2; SLITL1; TMEM257; XLID111"
ORIGIN      
        1 ctccttcctg caagaagcgt tgcccgttgg ctagctgctc ggtggggatc tgcctgccct
       61 gggggcgccg cccgcgctcc ccgcggtgct ctcgctcctg ggctgcgcca gtccgaggcg
      121 gtgccggctc ctttgcctcc ccgagtcgca gatgctgcgg gcgcctccgg gaaaagatct
      181 gggcggcgcg ctcgctcgat ggacacagga agatccagaa gctagtggca catctagcaa
      241 cagagccaga tcagaaccca ggttggaggt ggagtagttc agaatcaact gacgcagccg
      301 ggaattgagc tttgcaaagc cacttgcaag gaagggaagc atctgcccaa ccctccccca
      361 ccgcgcgccc tggatcctct gcctgccccc tcccccgtga cgtcacccta gtcctgtccc
      421 ggggagcctg caaagcctct cagattcaaa ctgctagacg cactgctgcc accgccaccg
      481 aattggaaac gcgcgcccag gctccgtcgt cgccttcgcc cgccgaccgg gccagccggc
      541 tctccgacct ccctacagaa tcgcacccca gtccctccct ggcagctcgg cttccctcag
      601 ctccaactct tctcttccgc tcctgcctcc tgtcggattt ttaatttctg cgcaccccca
      661 gtcaaattaa atcaaccaac aaaaagcagg gcatcccccc tggaagcagc gtcttatttt
      721 accttgttct cccacttcct gaagatgcta aactcctggt ggactgcaga ggagagggat
      781 tcagtcttct cctgatgtcg attgcgattt ctgctgggag ctcaagacgg gcgagctgcc
      841 cgagatctct tcgagatacc ccaggggagg aggagatggg caggatttag taggacaact
      901 cggttactaa tgacttggcg gctggctgcg accccccggg aaatcaggtt tgcctgtagg
      961 tacctgagtt gacaccgaag gtgcctaaag atgctgagcg gcgtttggtt cctcagtgtg
     1021 ttaaccgtgg ccgggatctt acagacagag agtcgcaaaa ctgccaaaga catttgcaag
     1081 atccgctgtc tgtgcgaaga aaaggaaaac gtactgaata tcaactgtga gaacaaagga
     1141 tttacaacag ttagcctgct ccagcccccc cagtatcgaa tctatcagct ttttctcaat
     1201 ggaaacctct tgacaagact gtatccaaac gaatttgtca attactccaa cgcggtgact
     1261 cttcacctag gtaacaacgg gttacaggag atccgaacgg gggcattcag tggcctgaaa
     1321 actctcaaaa gactgcatct caacaacaac aagcttgaga tattgaggga ggacaccttc
     1381 ctaggcctgg agagcctgga gtatctccag gccgactaca attacatcag tgccatcgag
     1441 gctggggcat tcagcaaact taacaagctc aaagtgctca tcctgaatga caaccttctg
     1501 ctttcactgc ccagcaatgt gttccgcttt gtcctgctga cccacttaga cctcaggggg
     1561 aataggctaa aagtaatgcc ttttgctggc gtccttgaac atattggagg gatcatggag
     1621 attcagctgg aggaaaatcc atggaattgc acttgtgact tacttcctct caaggcctgg
     1681 ctagacacca taactgtttt tgtgggagag attgtctgtg agactccctt taggttgcat
     1741 gggaaagacg tgacccagct gaccaggcaa gacctctgtc ccagaaaaag tgccagtgat
     1801 tccagtcaga ggggcagcca tgctgacacc cacgtccaaa ggctgtcacc tacaatgaat
     1861 cctgctctca acccaaccag ggctccgaaa gccagccggc cgcccaaaat gagaaatcgt
     1921 ccaactcctc gagtgactgt gtcaaaggac aggcaaagtt ttggacccat catggtgtac
     1981 cagaccaagt ctcctgtgcc tctcacctgt cccagcagct gtgtctgcac ctctcagagc
     2041 tcagacaatg gtctgaatgt aaactgccaa gaaaggaagt tcactaatat ctctgacctg
     2101 cagcccaaac cgaccagtcc aaagaaactc tacctaacag ggaactatct tcaaactgtc
     2161 tataagaatg acctcttaga atacagttct ttggacttac tgcacttagg aaacaacagg
     2221 attgcagtca ttcaggaagg tgcctttaca aacctgacca gtttacgcag actttatctg
     2281 aatggcaatt accttgaagt gctgtaccct tctatgtttg atggactgca gagcttgcaa
     2341 tatctctatt tagagtataa tgtcattaag gaaattaagc ctctgacctt tgatgctttg
     2401 attaacctac agctactgtt tctgaacaac aaccttcttc ggtccttacc tgataatata
     2461 tttgggggga cggccctaac caggctgaat ctgagaaaca accatttttc tcacctgccc
     2521 gtgaaagggg ttctggatca gctcccggct ttcatccaga tagatctgca ggagaacccc
     2581 tgggactgta cctgtgacat catggggctg aaagactgga cagaacatgc caattcccct
     2641 gtcatcatta atgaggtgac ttgcgaatct cctgctaagc atgcagggga gatactaaaa
     2701 tttctgggga gggaggctat ctgtccagac agcccaaact tgtcagatgg aaccgtcttg
     2761 tcaatgaatc acaatacaga cacacctcgg tcgcttagtg tgtctcctag ttcctatcct
     2821 gaactacaca ctgaagttcc actgtctgtc ttaattctgg gattgcttgt tgttttcatc
     2881 ttatctgtct gttttggggc tggtttattc gtctttgtct tgaaacgccg aaagggagtg
     2941 ccgagcgttc ccaggaatac caacaactta gacgtaagct cctttcaatt acagtatggg
     3001 tcttacaaca ctgagactca cgataaaaca gacggccatg tctacaacta tatcccccca
     3061 cctgtgggtc agatgtgcca aaaccccatc tacatgcaga aggaaggaga cccagtagcc
     3121 tattaccgaa acctgcaaga gttcagctat agcaacctgg aggagaaaaa agaagagcca
     3181 gccacacctg cttacacaat aagtgccact gagctgctag aaaagcaggc cacaccaaga
     3241 gagcctgagc tgctgtatca aaatattgct gagcgagtca aggaacttcc cagcgcaggc
     3301 ctagtccact ataacttttg taccttacct aaaaggcagt ttgccccttc ctatgaatct
     3361 cgacgccaaa accaagacag aatcaataaa accgttttat atggaactcc caggaaatgc
     3421 tttgtggggc agtcaaaacc caaccaccct ttactgcaag ctaagccgca atcagaaccg
     3481 gactacctcg aagttctgga aaaacaaact gcaatcagtc agctgtgaag ggaaatcatt
     3541 tacaacccta aggcatcaga ggatgctgct ccgaactgtt ggaaacaagg acattagctt
     3601 ttgtgtttgt ttttgttctc cctttcccag tgttaatggg ggactttgaa aatgtttggg
     3661 agataggatg aagtcatgat tttgcttttg caagttttcc tttaaattat ttctctctcg
     3721 ctctcctccc ctcctttttt tttttttttt ttttttcttt ttcccttctc ttcttaggaa
     3781 ccatcagtgg acatgaatgt ttctacaatg catttcttca tagattttgt ttatggtttt
     3841 gtttcttttt tcttctttgt ttttcagtgt gggagtggga agaggagatt atagtgactg
     3901 aagaaagaat aggcaaactt ttcaaatgaa aatggatatt tagtgtattt tgtagaagat
     3961 ctccaaagat cttttgtgac tacaacttct tttgtaaata atgatatatg gtatttccat
     4021 cgtcagttac cgagtatagc cactgggtat cactactttg tgttaaagtg ccttcgcact
     4081 ttaagtacat tacttaaatg ttgcttttag ctttgataaa ttgaaaatat tttaatgtgt
     4141 tgtatttttg aaattgaaaa cactgtaaaa tagattgatg tgtcagctat attaagtcaa
     4201 cgtacagttt gcttgagtta tagaaaccag cctgtcatca aatgattcta gttctaggac
     4261 tttgtaggct taactataaa atatttcctt tcctctgggt ttaagtgatt ttatttaagt
     4321 caactaaggg gatttaacag tggactagag gtaataagcc acctcagtca ggattaataa
     4381 ttcattaata aaatatattt aacccaatat cagagtgaat tgagcaatta atgcccttcc
     4441 ataaatcatt attttacact aacatggtga gtgttttaga ttattttcct aattaaaaga
     4501 acgtgacaca gctagtaata tatttttctg cattgaatta gatattttta tatatttaaa
     4561 tgaaaaagtc tgtatttcta actttttaat tgaaattaat attttttctg cctattgaaa
     4621 cattttctat aaacacacac cagtagaggc cgccacacac ctcatttaac aaagacatat
     4681 gagccattaa agacctcgaa ggaagacttc atgggtgaga ttaaaacttc ccaagtaagt
     4741 tctctgcaaa attcaaggta gcagagataa aaatgtatcc attactctat ttattttaga
     4801 tcacgggtta gactcataat ccttctcaag tttaacactt tctgacaaaa cagcattttc
     4861 ctcttgagtt taattgaagc attaatgggg tgctatcaaa tcaagtacta tttgcgtctc
     4921 caaatcgatt aatagttacc taaaccaaga cattaagcat ctttttcctt ctgccttctt
     4981 taggcttgtg ttacttgaag ttttccttgt cagcttgagc aagactttca ttttggtgtt
     5041 agcattaaaa tgattttaat tagccaagtc tatataacat ttatgaagcc ttattagact
     5101 gtaaataatt ttagatgcaa acgtgattgt gtgatttaaa caaacagccc ttctttacaa
     5161 caaaaaatag ttttgttttg tctattgtaa atccttatgc aactgggatg gtgatctgca
     5221 tataaagtag ttcagctttt caattcctta ttaaagcaag cgatggcgtc tgaaagaagc
     5281 acactgtttc cttttcataa ataggttact gcacataata atcctttatc gtcatgtgga
     5341 gattgaagtg gatactgata acttactttt aaagctttaa aattaccaat agtatattgt
     5401 ctgtcactat aaacaattca tgtgataggc tttcaattag aaattcctta aatccaaatt
     5461 atttggatta atgattactg gtgtaaaata gttgtttgta aaaacaatag aaggtaattg
     5521 tgtgtatata ataacgtaaa gggcattgaa gagaaacata tctttaacaa cataaaatct
     5581 ctgaatatct acagtggcaa gctaacatgc tcattctttg attagaggtg ataattccta
     5641 tttcgatcca ttagaagaaa gttgaaaatg gtgggctgaa atgatcttca agaaagttaa
     5701 tgtacagata ttttacattt cacagaagag gaactagaat attatgctag ttgaatgtgg
     5761 agaagactcc tggaaaccac ttcatctttg agtgaagtat ttatatataa aagagtttca
     5821 aaaatccttt tctgactgct ctcatttgat gcaatgataa atacagaata cagaggtagg
     5881 tattttggga agtgattgtg aaggcaaatt tgcatatata ttctgttaag atcattttca
     5941 ggcttaaatt atatgactag aggctcttga tgcagtgatt ccacttcagt gttcattttt
     6001 atttttctga aagtaaagat actcctgtaa aatgccattg tccatagaaa aaatattaac
     6061 tcattaagtt taaagacaga tgatacctta atattaactt acttacacga ttttaaagac
     6121 gcctactgag agaactcaaa tttataaact ctgttgccta ataattatgg tttaattcta
     6181 tatcctcttg cttgttacag ttatacttaa tttgcagtag atttttaaat gaaattattt
     6241 gaatgtattc cagactattt tatttaaaat catcatacat catatacttt gaacctttat
     6301 tttctaatgc aatcataaac attttaagtt ttattaactc actagcatcc ccactgacta
     6361 tattctgttt tgctttatct gctcaagcac tttcgaccat attttatttt aggattttta
     6421 tttttatctt ccacagctgg atattgctat ttcactttta tttcacatgc agctttaaga
     6481 cgtatgagca tcagcacagc aaaatggttc cagcctacag aatgcagtct cccagggccc
     6541 tgccaagaac atatctgtat gtctggccct acaaatgaca aatggtaatt cccttctatt
     6601 ttagctctta attagttgct ttcactattt ccgaatatac ctgtggctaa gtttttattg
     6661 aaacactcaa aaataccact tctcagtatg aacacaattg ctaagagcct aatttggttc
     6721 tggactatgg tcaacctgtg tgccttgtta gttctctcca gcagctggtg agtaaggaaa
     6781 tgacccttca atttcctctt ctttttcctc tgacctctgt gacttaattt ttcttaatgt
     6841 ctccaagtca tcaagggctt aataatttat gaattttaca aaaagcattt aaggaataag
     6901 aaagaggttc tgtgattttt cagactctga aaattcattt tgattctaca tattccagaa
     6961 atatactggg ttggatgcta gagtgaagaa agccgtccag acaattctcc cagtccattc
     7021 atttcttcat tcatttgttc attcagtagt tattgagtgc ttatttcctg ggtgcctggc
     7081 tctaggctat gtcctgagac atacagtgga cagggtctct accctcctca caacaccctc
     7141 ttcaccctcc acgccacccc ctactactca ctctcaccct agcaaggagc ttcgtgctaa
     7201 taagagagag tcttacctga atggcaatcg cccagattaa cagtggagac agtaatgcaa
     7261 tgcaggaagt taagttttta aaggtgattc tgtgcagtaa ggtataaaac agatatataa
     7321 taaatagcct agcttagtct aacatctctt tagaattaca cagctaaaaa ggaaaaaaaa
     7381 caccaaaata agataaaata aaacaaattt aaacaccaaa ataagatata ataaaacatt
     7441 tgtttttgca aaataaggcc caatgttatg gcctaatgaa agctatatac ttgtgctatc
     7501 taaagcacta ctttgtaaag atgactaccc aagattgtaa atacaaaatt taaaaaggta
     7561 cttaaatttt ctggaatatc catgtttcag aggtaatatt tactttctat ttcagtggct
     7621 taaattataa cgttttggct taagtgtctt ttatcaatac aatgataaga caccttaatc
     7681 ctgagagaga aaattaagta ctgtatatag gtgtactttg cttctcacaa tgattgtgca
     7741 aaaagtcacg tgtaaattga acttttgtaa atcaaattgt attttaaatg cattagggga
     7801 gctgccattt agaggaaact tgtgaattct ttcataaagc agaaaaccat tttataatac
     7861 aaataaccat tctctgattt atctcttttg tatgtttgga ttttcaatat cgactttgct
     7921 taaaacagag cccacctgca tagtaactgt gttttgccaa ggctgcttgt gctaccagtt
     7981 tgctggtggc taacggcttg tgcttgaaag tcttctgaag tctgatgtga attgagctat
     8041 caagcaatgc tatcatagca cagtagcagt cctgaacagt ctgagcagcc aacccatttc
     8101 aacaaaattg aacacaggac tcttctgctc agcagcatct cttttctcag atgtggccat
     8161 gttacagtag agggtattcc ataagcacat attccataaa gtgctcagag tcacaggttt
     8221 tataataaat tatgttatta tgtaaacgaa ttgcatgcat gttgaaattt tttagcagta
     8281 ctttagcttg aaagtactcg tacaaatact gttagattta gttgcaaata attgttctca
     8341 agttattgca ataaatgtca aatgaaacaa gctcttgtgt aaatagactt ctgtgcctaa
     8401 tagtgacatt gtttcaaaaa a
//
