LOCUS       NM_001129820            7169 bp    mRNA    linear   PRI 20-MAY-2024
DEFINITION  Homo sapiens schlafen family member 14 (SLFN14), mRNA.
ACCESSION   NM_001129820 XM_001715630 XM_017024576 XM_496207 XM_940940
VERSION     NM_001129820.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7169)
  AUTHORS   Valenzuela,C., Saucedo,S. and Llano,M.
  TITLE     Schlafen14 Impairs HIV-1 Expression in a Codon Usage-Dependent
            Manner
  JOURNAL   Viruses 16 (4), 502 (2024)
   PUBMED   38675845
  REMARK    GeneRIF: Schlafen14 Impairs HIV-1 Expression in a Codon
            Usage-Dependent Manner.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7169)
  AUTHORS   Ver Donck,F., Ramaekers,K., Thys,C., Van Laer,C., Peerlinck,K., Van
            Geet,C., Eto,K., Labarque,V. and Freson,K.
  TITLE     Ribosome dysfunction underlies SLFN14-related thrombocytopenia
  JOURNAL   Blood 141 (18), 2261-2274 (2023)
   PUBMED   36790527
  REMARK    GeneRIF: Ribosome dysfunction underlies SLFN14-related
            thrombocytopenia.
REFERENCE   3  (bases 1 to 7169)
  AUTHORS   Mao,Y., Ding,J.W., Chen,M.S., Cen,S. and Li,X.Y.
  TITLE     [SLFN14 inhibits LINE-1 transposition activity]
  JOURNAL   Yi Chuan 42 (7), 669-679 (2020)
   PUBMED   32694106
  REMARK    GeneRIF: [SLFN14 inhibits LINE-1 transposition activity].
REFERENCE   4  (bases 1 to 7169)
  AUTHORS   Stapley,R.J., Pisareva,V.P., Pisarev,A.V. and Morgan,N.V.
  TITLE     SLFN14 gene mutations associated with bleeding
  JOURNAL   Platelets 31 (3), 407-410 (2020)
   PUBMED   31378119
  REMARK    GeneRIF: SLFN14 gene mutations associated with bleeding.
            Review article
REFERENCE   5  (bases 1 to 7169)
  AUTHORS   Su,W., Wang,R.C., Lohano,M.K., Wang,L., Zhu,P., Luo,Y., Guo,L.J.,
            Lv,Q., Jiang,H., Wang,J.H., Mei,L., Weng,J., Su,L. and Dong,N.G.
  TITLE     Identification of Two Mutations in PCDHGA4 and SLFN14 Genes in an
            Atrial Septal Defect Family
  JOURNAL   Curr Med Sci 38 (6), 989-996 (2018)
   PUBMED   30536060
  REMARK    GeneRIF: The mutations of c.1187delT of PCDHGA4 and c.2557insC of
            SLFN14 may be pathogenic factors contributing to the development of
            ASD.
REFERENCE   6  (bases 1 to 7169)
  AUTHORS   Seong,R.K., Seo,S.W., Kim,J.A., Fletcher,S.J., Morgan,N.V.,
            Kumar,M., Choi,Y.K. and Shin,O.S.
  TITLE     Schlafen 14 (SLFN14) is a novel antiviral factor involved in the
            control of viral replication
  JOURNAL   Immunobiology 222 (11), 979-988 (2017)
   PUBMED   28734654
  REMARK    GeneRIF: these data suggest that SLFN14 is a novel antiviral factor
            for both DNA and RNA viruses
REFERENCE   7  (bases 1 to 7169)
  AUTHORS   Marconi,C., Di Buduo,C.A., Barozzi,S., Palombo,F., Pardini,S.,
            Zaninetti,C., Pippucci,T., Noris,P., Balduini,A., Seri,M. and
            Pecci,A.
  TITLE     SLFN14-related thrombocytopenia: identification within a large
            series of patients with inherited thrombocytopenia
  JOURNAL   Thromb Haemost 115 (5), 1076-1079 (2016)
   PUBMED   26769223
  REMARK    GeneRIF: In a family with three affected individuals we found the
            c.667C>T variant in SLFN14 predicted to result in the p.Arg223Trp
            substitution within the ATPase- AAA-4 domain of SLFN14. The variant
            segregated with macrothrombocytopenia within the pedigree.
REFERENCE   8  (bases 1 to 7169)
  AUTHORS   Fletcher,S.J., Johnson,B., Lowe,G.C., Bem,D., Drake,S.,
            Lordkipanidze,M., Guiu,I.S., Dawood,B., Rivera,J., Simpson,M.A.,
            Daly,M.E., Motwani,J., Collins,P.W., Watson,S.P. and Morgan,N.V.
  CONSRTM   UK Genotyping and Phenotyping of Platelets study group
  TITLE     SLFN14 mutations underlie thrombocytopenia with excessive bleeding
            and platelet secretion defects
  JOURNAL   J Clin Invest 125 (9), 3600-3605 (2015)
   PUBMED   26280575
  REMARK    GeneRIF: These results identify SLFN14 mutations as cause for an
            inherited thrombocytopenia with excessive bleeding, outlining a
            fundamental role for SLFN14 in platelet formation and function.
REFERENCE   9  (bases 1 to 7169)
  AUTHORS   Pisareva,V.P., Muslimov,I.A., Tcherepanov,A. and Pisarev,A.V.
  TITLE     Characterization of Novel Ribosome-Associated Endoribonuclease
            SLFN14 from Rabbit Reticulocytes
  JOURNAL   Biochemistry 54 (21), 3286-3301 (2015)
   PUBMED   25996083
REFERENCE   10 (bases 1 to 7169)
  AUTHORS   Schwarz,D.A., Katayama,C.D. and Hedrick,S.M.
  TITLE     Schlafen, a new family of growth regulatory genes that affect
            thymocyte development
  JOURNAL   Immunity 9 (5), 657-668 (1998)
   PUBMED   9846487
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC015911.8, BC157877.1 and
            BU658532.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On or before Aug 27, 2019 this sequence version replaced
            XM_017024576.1, NM_001129820.1.
            
            Summary: The protein encoded by this gene plays an important role
            in platelet formation and function. Defects in this gene are a
            cause of thrombocytopenia with excessive bleeding. [provided by
            RefSeq, Jul 2016].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138524.1059465.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2149004, SAMEA2154529
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000674182.1/ ENSP00000501524.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AC015911.8         148337-148389       c
            54-132              AC015911.8         147297-147375       c
            133-147             AC015911.8         145662-145676       c
            148-1241            BC157877.1         2-1095
            1242-1329           BU658532.1         236-323
            1330-3029           BC157877.1         1184-2883
            3030-7169           AC015911.8         131555-135694       c
FEATURES             Location/Qualifiers
     source          1..7169
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q12"
     gene            1..7169
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /note="schlafen family member 14"
                     /db_xref="GeneID:342618"
                     /db_xref="HGNC:HGNC:32689"
                     /db_xref="MIM:614958"
     exon            1..53
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     exon            54..132
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     exon            133..1236
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..2915
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /codon_start=1
                     /product="protein SLFN14"
                     /protein_id="NP_001123292.1"
                     /db_xref="CCDS:CCDS45650.1"
                     /db_xref="GeneID:342618"
                     /db_xref="HGNC:HGNC:32689"
                     /db_xref="MIM:614958"
                     /translation="MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSR
                     IIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQG
                     HNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRG
                     RPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTK
                     KVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIE
                     KLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDN
                     SVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQR
                     HLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRK
                     EQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCI
                     IPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCE
                     FFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYV
                     CESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNIT
                     HPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAK
                     VMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYV
                     ARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVW
                     GSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY"
     exon            1237..1365
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..2080
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..7169
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5099..5104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /note="hexamer: AATAAA"
     polyA_site      5120
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /note="major polyA site"
     regulatory      7146..7151
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
                     /note="hexamer: AATAAA"
     polyA_site      7169
                     /gene="SLFN14"
                     /gene_synonym="BDPLT20"
ORIGIN      
        1 agactacagc cagatgtgaa actgaagcag caagaggaaa cacaggagca taggaagtga
       61 gaaggcaacc aagaacaaat tgatatcagg ggagtgcaca tgtcttgccg gatgcctgct
      121 ttcttcctct tggaactcct ttcttttatt gtttggagca cagaggggct gctgaaatgg
      181 agagtctcaa gactgatact gaaatgccgt atcctgaggt aatagtagat gtgggcagag
      241 tgatttttgg agaagaaaac aggaagaaga tgaccaacag ctgtttgaaa agatctgaga
      301 attctagaat tatccgggct atatgtgcac tgttaaattc tggaggtggt gtgatcaaag
      361 cagagattga tgataaaacc tatagttacc aatgccatgg gctgggacag gatttggaaa
      421 cttcttttca aaagctcctt ccttcaggtt cacagaaata ccttgactac atgcagcagg
      481 ggcacaatct cctgattttt gtgaagtcat ggagcccaga tgttttcagc cttccactaa
      541 ggatttgcag cttgcgctcc aatttgtatc ggagagatgt gacttctgct atcaacttga
      601 gtgctagcag tgccctggag cttctcagag agaaggggtt tagagcccaa agaggaagac
      661 caagggtgaa gaagttgcat cctcagcagg ttctcaatag atgcattcag gaagaggaag
      721 atatgaggat attggcctca gaatttttta aaaaggacaa actcatgtat aaggagaaac
      781 tcaactttac tgagtcaaca catgttgaat ttaaaaggtt caccaccaaa aaagtcatac
      841 ctcggattaa ggaaatgctg cctcattatg tttctgcatt tgccaacact caagggggat
      901 atgtcctcat tggggtggat gataagagca aagaagtggt tggatgtaag tgggaaaaag
      961 tgaatcctga cttactaaaa aaagaaatcg aaaactgcat agaaaaattg cctacattcc
     1021 acttctgctg tgagaagcca aaggtaaatt tcactacaaa aatcctgaat gtgtaccaaa
     1081 aagatgtcct ggatggttat gtctgtgtga ttcaagtgga gcccttctgt tgcgtggtgt
     1141 ttgcagaggc cccagattcc tggatcatga aagacaattc tgtcacacgg ctgacagctg
     1201 agcagtgggt ggtcatgatg ctggatactc agtcagctcc tcccagtttg gtcacagact
     1261 acaactcttg cctgatttca tcagcttcat ctgcacgaaa aagtcccgga tatcccataa
     1321 aagtccacaa atttaaggag gctctgcaac gacatttgtt tccagtgaca caggaagagg
     1381 tacaatttaa accagaatcc ctctgtaaga agctgttctc agatcataaa gaactggagg
     1441 gtttaatgaa gaccctgata catccttgtt ctcaggggat tgtgatattt tctagaagct
     1501 gggctggtga tgttggcttc aggaaagaac agaatgtcct gtgtgatgct ctcctgatag
     1561 cagttaacag ccccgtggta ctctatacaa tcttaataga ccccaattgg cctggaggac
     1621 ttgaatatgc ccgaaacaca gctcatcagt taaagcagaa actgcaaact gttggtggtt
     1681 acacagggaa agtgtgcatc attccaaggc tgatacacct gagcagcaca cagagtagac
     1741 ctggtgagat ccccctgcgt taccccaggt cctacaggct tgctgatgag gaggaaatgg
     1801 aagacttgct gcaggctctg gtggtggtct ccctgtcctc cagatctctt ctgagtgacc
     1861 agatgggctg tgaatttttc aacttgctca taatggagca gagccagttg ctttctgaga
     1921 gtcttcagaa gacacgtgaa ttattcatct actgctttcc aggagtcagg aagacagccc
     1981 tagccataaa gatcatggag aaaattaagg acttgtttca ctgcaaacca aaagagatcc
     2041 tctatgtttg tgaaagcgac tccctaaagg attttgtgac ccaacaaacc acctgccaag
     2101 ctgtgaccag gaaaactttc atgcaagggg agtttctaaa gattaaacac atagtgatgg
     2161 atgagactga gaatttctgc agcaaatatg gcaattggta catgaaggct aagaacatca
     2221 cccatccaaa ggcgaagggg actggaagtg aaaaccttca ccatgggatt ctctggcttt
     2281 ttcttgaccc ttttcaaatc catcacgcag atgtcaatgg ccttccccct ccatctgctc
     2341 agtttcctcg aaaaacaatc accagtggga tccactgtgc tctggaaata gcgaaggtta
     2401 tgaaagaaga aatgaagagg atcaaagaaa atcctccctc caacatgtct ccagacacat
     2461 tagcattgtt cagcgagact gcctatgagg aagcaacgtg tgcccaggct ctgcctgggg
     2521 tgtgtgagac aaagactaat ctgacaacag aacaaatagc taactatgtg gcaagaaaat
     2581 gtcacagcct gttccagtgt ggctatctgc ccaaagatat agcaattctg tgcaggagag
     2641 gggaggacag aggacgctat aggcttgcac tactcaaagc aatggaatta attgagaccc
     2701 acagaccatc agaggttgtg tttagcccgg ccaccggtgt ttggggaagt cacattgttt
     2761 tagacagtat tcagcaattt tcaggcctgg agaggactgt cgtgtttggg cttagtccag
     2821 aatgtgacca gtcagaggaa tttcataagc tctgctttgc ttcaagagcc attaaacacc
     2881 tctacctgct ttatgaaaag agggcagcct actgaaaatt attacaaata atagaggaag
     2941 acaggaagag cagagtcctt tctcctagac aggtagcagt gactccattt taatattaca
     3001 agtgaggaaa tcaaggcaca tcagtatggc ctggagccac agaaatgtct cttggagctg
     3061 agccttccac tctatttcaa tgccactggc cttttcacaa tttccttcac ctcctaccta
     3121 tacaattaca atagacttca ttagtcccct gtctccagct ttcccactca atccagctgt
     3181 catccatcag agaatttttc ctcaaataga gaactgattt tatgtaatac cttgctaaca
     3241 tatcttcaat gagtccccac agccttcaaa cctaaccaat tttcaaggct ttcattaata
     3301 tgccctgact tgctctccca accacatcct ttattgtatc tccatctccc catgtttctc
     3361 atgcacccca gcccacctgg cataattttt gggtggtggt atggtgccct ccaggctggt
     3421 tactttgact gcataggtct caaaagtagc caattgactg gcacctcata ctggctatgg
     3481 gtctcaagct ttccaggtcc agaacttgat tgcctttttg taccaagtct agatcagtct
     3541 cttggggatg ctttatgcta atcaagctca caaaggacca atgcatacat caaaatgtta
     3601 ctctgttaat ttatagtgag gaccatagtc ataagtgggt caaatgcttt tgctaatcag
     3661 tgccctcaac agtaatatag gaagccaaat tatatgaaca tagccttaca gtaagggaag
     3721 ctggtaattt gattcaaatc ttaaaaatct tcagattata ttagactatt gcaatatcta
     3781 ttaggttggt gcaaaagtgc aaaagccaca attacttttg caccaactta atataaaata
     3841 agattgcaat aatttctaaa ataaagatat ttctatcaca aggactagac aaattagttt
     3901 acagtttaca agctaaagca aatttagaat gctaaggatg actagttttt cattattctt
     3961 tgccctcaga tgaatttttt tttctctgtc ttggtttcta aaatttccag gttcaccacc
     4021 aaccctctcc ttactgcccc caacatatac aaattttgcc tacatttatc ctctatgtat
     4081 gtgaatacat tcatgtaggc tagaaatgcc ttatactctg ccgctggcct ggaaagtagt
     4141 cttcctacaa ggggcctttg cacatctctg atttcttcca ttatgacttg gtgctaattt
     4201 ttaaatccaa ctctcagagt ttatggggat ccttggtggc aactttacca ccaacaccac
     4261 ccacacacat ccccgactcc tggtctgtgc ctgtgccatt ttctcagtct ttaaaccctt
     4321 ttctgtcccc tccacctttg aaatccttac ttggcaatca catccttttt caaatgccta
     4381 ctacctcaat taaactttta ttatctccct aagtgaaact ttccaatgta tatgatacat
     4441 attagaaatg aaatcaaagt tccccttttc tagtcagttc cccaaatggc tgagccaatt
     4501 ctgtactctt caaattactc ttgcttttgc aaggattttt aaattgcttt ggaagtattc
     4561 atatttccaa actgttttta acttctagaa aagtttagga taacttgatt gactctgggg
     4621 aggcttgaat ccaggagaca tgtggaaatt ttggttatga ttttagataa agcccctcag
     4681 ccttccaaga ggtggaagag caggcagggt ttcgagaagc tctcttagct gcctttctga
     4741 attgcttagg cccattagaa gggctagtct gtacctaggc acgggttgaa aagaaaaacc
     4801 tctcccttgc ttcctactgc tctaattacc tggtgtttct tcctttttac ctttccttgg
     4861 gggctttagg gtagttttgg ataggaggaa atgaagttca gcaatcggtt ttgcaaaaga
     4921 tgccagtgca ttgacattct gatgtaggga gatgtatgaa ttctataaaa ataatttaaa
     4981 cagtcaaagt caacagagta tgaaggagta tgagtgggac aaggaattgc tatattttag
     5041 tcataagcct tagtaccatt tgacttttta aaatatatgc atgcatcata taatttttaa
     5101 taaaagaatt gatttgtaaa gaattgtttt aaatattgaa tttgagagtc tttgtcagtt
     5161 cttagtctag tgaaacaatt caatcaggat gaaagtagaa taactaactc agtgattctc
     5221 aaccctggat gctcattata atttcctggg cgacttaaaa aaaatcagtg atcaggccag
     5281 acaccagact aattaacctc agtgtgtctg aacacaggct cgggcatcgg tatttattaa
     5341 atgttgtcca ggcagggtgc agtggctggt gcctgtaata ccagaacttt gagaggctga
     5401 ggtctggggg aatcacttga agccaggagt tggagaccag cctgggcaac ataacaagac
     5461 cccatctcta caaaaaaaat ttttttaaaa acttagttgg gcatggtggt gcatgctttt
     5521 aatcctagct actccagagg ccaaggtggg aggatcactt gagcccagga gtttgaggct
     5581 acagtgacct atgattactc cactgcactc cagcctgggt tacagagcaa gactctatct
     5641 cttaaaaaaa atccaaatga ttctaatatg tcacaagggt tgagaaccat tgaacccttc
     5701 tcctagtctg ttctttctgt cctcaaaaaa tgtgtgcaca tttctcttcc tattaagact
     5761 gtgagctcct tgagagtaag aggatgagtc acttacacat ccttatttcc cctagagcaa
     5821 ctagtacagt gcctcacaca gggcaggtgc tcagtaaata tttgctgaat tgtacttgta
     5881 gcttttagaa aactagaatc tacaatgatt caattcgata gtatgaattt ctaatgttag
     5941 agatttcaaa gaagtcagtg tggagaataa tctttaacac tgtaataatg aagaataagg
     6001 gaacaataaa ggcaactcaa ttgtttttag gcaacaggtc aaattaagga tctatgatga
     6061 tagttcatta gattcaaatg taagattagg aactggtggg gactaagaat aatggactaa
     6121 cttggttgtt ttagaattct caatgttttc tacaaagtct taatatgatg gataaagcaa
     6181 ttaactaaat gaaataacta agataaaaga gaagctttag aaactgtgag aagcttctaa
     6241 aacttacttt taaaaagaag ggtaatataa tattatcatg gaagcttcgg aaatggagaa
     6301 aggcaaaatt aaaagttctt aaatcaggct gggcgcaggg gctcatgctg gtaatcctag
     6361 cactttggga ggctgaggtg ggtgaatcac ctgaggtcag gagttcaaga ccagcctgac
     6421 caacatggag aaaccctgtc tccactaaaa atacaaaatt agctgggcat ggtggcgcat
     6481 gcctgtaatc ccagctactt gggaggctga ggcaggagaa ttgcttgaac ctgggaggtg
     6541 gaggttgcag tgagctgaga ttgcgccact gcacttcagc ctgggcaaca agagtgaaac
     6601 tctgtctcaa aaaaaaaaaa aaaaagttct taaatcatct tgttatctgg gtgtaacatt
     6661 ttttcatttt tgcttattta tttctattct ttgttgatat ggaaaaatat tttcacacag
     6721 ttatgatcaa gttgtgccat caactttata acgtatatgt gtgctttttc catttaattg
     6781 ttttgtgaga tattgctata gactacatta ttgttcccaa tatttcctac ctctctatat
     6841 ctataccctt tgtagttact aacattagag gtagagatat tttccacccc tgtaatgtgg
     6901 ccttggtcat gtgacttgga atgttagtag ttctgatgtg cacagaggct gtacatggac
     6961 tttcagcatt gggtttactc tctcgggttt ctgctgtttc catacaaaga atgtaccctg
     7021 ggtggcccac cagccactga gatatgtgaa tccaacttga actcaactca tggcctggag
     7081 ccaagttcca ccagtcctaa ctagcttagc caaaatccag ctgatctgaa agtgcatgaa
     7141 tgagaaataa aagcttatta tttaatgac
//
