LOCUS       NM_173488               2682 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens solute carrier organic anion transporter family member
            6A1 (SLCO6A1), transcript variant 1, mRNA.
ACCESSION   NM_173488
VERSION     NM_173488.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2682)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 2682)
  AUTHORS   Khan,R.A., Chen,J., Wang,M., Wen,Z., Shen,J., Song,Z., Li,Z.,
            Wang,Q., Li,W., Xu,Y., Ji,W. and Shi,Y.
  TITLE     Analysis of association between common variants in the SLCO6A1 gene
            with schizophrenia, bipolar disorder and major depressive disorder
            in the Han Chinese population
  JOURNAL   World J Biol Psychiatry 17 (2), 140-146 (2016)
   PUBMED   26861727
  REMARK    GeneRIF: No association of gene SLCO6A1 rs6878284 with
            schizophrenia; rs7734060 could be a risk locus for major depressive
            disorder in the Han Chinese population
            Erratum:[World J Biol Psychiatry. 2019 Dec;20(10):827. doi:
            10.1080/15622975.2017.1344498.. PMID: 28699376]
REFERENCE   3  (bases 1 to 2682)
  AUTHORS   Brenner,S., Klameth,L., Riha,J., Scholm,M., Hamilton,G., Bajna,E.,
            Ausch,C., Reiner,A., Jager,W., Thalhammer,T. and Buxhofer-Ausch,V.
  TITLE     Specific expression of OATPs in primary small cell lung cancer
            (SCLC) cells as novel biomarkers for diagnosis and therapy
  JOURNAL   Cancer Lett 356 (2 Pt B), 517-524 (2015)
   PUBMED   25301452
  REMARK    GeneRIF: High OATP6A1 expression is associated with small cell lung
            cancer.
REFERENCE   4  (bases 1 to 2682)
  AUTHORS   Zhang,C. and Pierce,B.L.
  TITLE     Genetic susceptibility to accelerated cognitive decline in the US
            Health and Retirement Study
  JOURNAL   Neurobiol Aging 35 (6), 1512 (2014)
   PUBMED   24468470
REFERENCE   5  (bases 1 to 2682)
  AUTHORS   Ripke,S., O'Dushlaine,C., Chambert,K., Moran,J.L., Kahler,A.K.,
            Akterin,S., Bergen,S.E., Collins,A.L., Crowley,J.J., Fromer,M.,
            Kim,Y., Lee,S.H., Magnusson,P.K., Sanchez,N., Stahl,E.A.,
            Williams,S., Wray,N.R., Xia,K., Bettella,F., Borglum,A.D.,
            Bulik-Sullivan,B.K., Cormican,P., Craddock,N., de Leeuw,C.,
            Durmishi,N., Gill,M., Golimbet,V., Hamshere,M.L., Holmans,P.,
            Hougaard,D.M., Kendler,K.S., Lin,K., Morris,D.W., Mors,O.,
            Mortensen,P.B., Neale,B.M., O'Neill,F.A., Owen,M.J.,
            Milovancevic,M.P., Posthuma,D., Powell,J., Richards,A.L.,
            Riley,B.P., Ruderfer,D., Rujescu,D., Sigurdsson,E., Silagadze,T.,
            Smit,A.B., Stefansson,H., Steinberg,S., Suvisaari,J., Tosato,S.,
            Verhage,M., Walters,J.T., Levinson,D.F., Gejman,P.V., Kendler,K.S.,
            Laurent,C., Mowry,B.J., O'Donovan,M.C., Owen,M.J., Pulver,A.E.,
            Riley,B.P., Schwab,S.G., Wildenauer,D.B., Dudbridge,F., Holmans,P.,
            Shi,J., Albus,M., Alexander,M., Campion,D., Cohen,D., Dikeos,D.,
            Duan,J., Eichhammer,P., Godard,S., Hansen,M., Lerer,F.B.,
            Liang,K.Y., Maier,W., Mallet,J., Nertney,D.A., Nestadt,G.,
            Norton,N., O'Neill,F.A., Papadimitriou,G.N., Ribble,R.,
            Sanders,A.R., Silverman,J.M., Walsh,D., Williams,N.M., Wormley,B.,
            Arranz,M.J., Bakker,S., Bender,S., Bramon,E., Collier,D.,
            Crespo-Facorro,B., Hall,J., Iyegbe,C., Jablensky,A., Kahn,R.S.,
            Kalaydjieva,L., Lawrie,S., Lewis,C.M., Lin,K., Linszen,D.H.,
            Mata,I., McIntosh,A., Murray,R.M., Ophoff,R.A., Powell,J.,
            Rujescu,D., Van Os,J., Walshe,M., Weisbrod,M., Wiersma,D.,
            Donnelly,P., Barroso,I., Blackwell,J.M., Bramon,E., Brown,M.A.,
            Casas,J.P., Corvin,A.P., Deloukas,P., Duncanson,A., Jankowski,J.,
            Markus,H.S., Mathew,C.G., Palmer,C.N., Plomin,R., Rautanen,A.,
            Sawcer,S.J., Trembath,R.C., Viswanathan,A.C., Wood,N.W.,
            Spencer,C.C., Band,G., Bellenguez,C., Freeman,C., Hellenthal,G.,
            Giannoulatou,E., Pirinen,M., Pearson,R.D., Strange,A., Su,Z.,
            Vukcevic,D., Donnelly,P., Langford,C., Hunt,S.E., Edkins,S.,
            Gwilliam,R., Blackburn,H., Bumpstead,S.J., Dronov,S., Gillman,M.,
            Gray,E., Hammond,N., Jayakumar,A., McCann,O.T., Liddle,J.,
            Potter,S.C., Ravindrarajah,R., Ricketts,M.,
            Tashakkori-Ghanbaria,A., Waller,M.J., Weston,P., Widaa,S.,
            Whittaker,P., Barroso,I., Deloukas,P., Mathew,C.G., Blackwell,J.M.,
            Brown,M.A., Corvin,A.P., McCarthy,M.I., Spencer,C.C., Bramon,E.,
            Corvin,A.P., O'Donovan,M.C., Stefansson,K., Scolnick,E.,
            Purcell,S., McCarroll,S.A., Sklar,P., Hultman,C.M. and
            Sullivan,P.F.
  CONSRTM   Multicenter Genetic Studies of Schizophrenia Consortium; Psychosis
            Endophenotypes International Consortium; Wellcome Trust Case
            Control Consortium 2
  TITLE     Genome-wide association analysis identifies 13 new risk loci for
            schizophrenia
  JOURNAL   Nat Genet 45 (10), 1150-1159 (2013)
   PUBMED   23974872
REFERENCE   6  (bases 1 to 2682)
  AUTHORS   Kenny,E.E., Pe'er,I., Karban,A., Ozelius,L., Mitchell,A.A.,
            Ng,S.M., Erazo,M., Ostrer,H., Abraham,C., Abreu,M.T., Atzmon,G.,
            Barzilai,N., Brant,S.R., Bressman,S., Burns,E.R., Chowers,Y.,
            Clark,L.N., Darvasi,A., Doheny,D., Duerr,R.H., Eliakim,R.,
            Giladi,N., Gregersen,P.K., Hakonarson,H., Jones,M.R., Marder,K.,
            McGovern,D.P., Mulle,J., Orr-Urtreger,A., Proctor,D.D., Pulver,A.,
            Rotter,J.I., Silverberg,M.S., Ullman,T., Warren,S.T., Waterman,M.,
            Zhang,W., Bergman,A., Mayer,L., Katz,S., Desnick,R.J., Cho,J.H. and
            Peter,I.
  TITLE     A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests
            novel susceptibility loci
  JOURNAL   PLoS Genet 8 (3), e1002559 (2012)
   PUBMED   22412388
REFERENCE   7  (bases 1 to 2682)
  AUTHORS   Stefansson,H., Ophoff,R.A., Steinberg,S., Andreassen,O.A.,
            Cichon,S., Rujescu,D., Werge,T., Pietilainen,O.P., Mors,O.,
            Mortensen,P.B., Sigurdsson,E., Gustafsson,O., Nyegaard,M.,
            Tuulio-Henriksson,A., Ingason,A., Hansen,T., Suvisaari,J.,
            Lonnqvist,J., Paunio,T., Borglum,A.D., Hartmann,A., Fink-Jensen,A.,
            Nordentoft,M., Hougaard,D., Norgaard-Pedersen,B., Bottcher,Y.,
            Olesen,J., Breuer,R., Moller,H.J., Giegling,I., Rasmussen,H.B.,
            Timm,S., Mattheisen,M., Bitter,I., Rethelyi,J.M.,
            Magnusdottir,B.B., Sigmundsson,T., Olason,P., Masson,G.,
            Gulcher,J.R., Haraldsson,M., Fossdal,R., Thorgeirsson,T.E.,
            Thorsteinsdottir,U., Ruggeri,M., Tosato,S., Franke,B.,
            Strengman,E., Kiemeney,L.A., Melle,I., Djurovic,S., Abramova,L.,
            Kaleda,V., Sanjuan,J., de Frutos,R., Bramon,E., Vassos,E.,
            Fraser,G., Ettinger,U., Picchioni,M., Walker,N., Toulopoulou,T.,
            Need,A.C., Ge,D., Yoon,J.L., Shianna,K.V., Freimer,N.B.,
            Cantor,R.M., Murray,R., Kong,A., Golimbet,V., Carracedo,A.,
            Arango,C., Costas,J., Jonsson,E.G., Terenius,L., Agartz,I.,
            Petursson,H., Nothen,M.M., Rietschel,M., Matthews,P.M., Muglia,P.,
            Peltonen,L., St Clair,D., Goldstein,D.B., Stefansson,K. and
            Collier,D.A.
  CONSRTM   Genetic Risk and Outcome in Psychosis (GROUP)
  TITLE     Common variants conferring risk of schizophrenia
  JOURNAL   Nature 460 (7256), 744-747 (2009)
   PUBMED   19571808
REFERENCE   8  (bases 1 to 2682)
  AUTHORS   Prachukthum,S., Nunnarumit,P., Pienvichit,P., Chuansumrit,A.,
            Songdej,D., Kajanachumpol,S., Pakakasama,S. and Hongeng,S.
  TITLE     Genetic polymorphisms in Thai neonates with hyperbilirubinemia
  JOURNAL   Acta Paediatr 98 (7), 1106-1110 (2009)
   PUBMED   19397531
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 2682)
  AUTHORS   Suzuki,T., Onogawa,T., Asano,N., Mizutamari,H., Mikkaichi,T.,
            Tanemoto,M., Abe,M., Satoh,F., Unno,M., Nunoki,K., Suzuki,M.,
            Hishinuma,T., Goto,J., Shimosegawa,T., Matsuno,S., Ito,S. and
            Abe,T.
  TITLE     Identification and characterization of novel rat and human
            gonad-specific organic anion transporters
  JOURNAL   Mol Endocrinol 17 (7), 1203-1215 (2003)
   PUBMED   12677006
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY036202.1, AF505657.1, BM554439.1, HY200806.1, DB513513.1 and
            AC113417.2.
            
            On May 17, 2019 this sequence version replaced NM_173488.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1). Both variants 1 and
            2 encode isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF505657.1, HM005487.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000506729.6/ ENSP00000421339.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                HY036202.1         18-31
            15-549              AF505657.1         1-535
            550-679             BM554439.1         552-681
            680-2366            AF505657.1         666-2352
            2367-2506           HY200806.1         1-140               c
            2507-2674           DB513513.1         257-424
            2675-2682           AC113417.2         60310-60317         c
FEATURES             Location/Qualifiers
     source          1..2682
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q21.1"
     gene            1..2682
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="solute carrier organic anion transporter family
                     member 6A1"
                     /db_xref="GeneID:133482"
                     /db_xref="HGNC:HGNC:23613"
                     /db_xref="MIM:613365"
     exon            1..515
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..2317
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cancer/testis antigen 48; gonad-specific transporter;
                     testis-specific organic anion transporter; solute carrier
                     family 21 member 19; organic anion-transporting
                     polypeptide I; testicular tissue protein Li 174"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 6A1 isoform 1"
                     /protein_id="NP_775759.3"
                     /db_xref="CCDS:CCDS34206.1"
                     /db_xref="GeneID:133482"
                     /db_xref="HGNC:HGNC:23613"
                     /db_xref="MIM:613365"
                     /translation="MFVGVARHSGSQDEVSRGVEPLEAARAQPAKDRRAKGTPKSSKP
                     GKKHRYLRLLPEALIRFGGFRKRKKAKSSVSKKPGEVDDSLEQPCGLGCLVSTCCECC
                     NNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI
                     FIAFYGDRKKVIWFVASSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQ
                     SSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMI
                     GYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSC
                     FPNNMPGSTRIKARKRKQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICLALSK
                     ATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMS
                     CKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGNLTAPCNEKCRC
                     SSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLITADAEGDFIDA
                     RPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVILR
                     IFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKLCTII
                     FTTIAFFIYKRRLNENTDFPDVTVKNPKVKKKEETDL"
     exon            516..773
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            774..959
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1056
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1178
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1288
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1433
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1629
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1783
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1971
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2036
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2174
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..2332
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2682
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2488..2493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="hexamer: AATAAA"
     polyA_site      2511
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="major polyA site"
     regulatory      2563..2568
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="hexamer: ATTAAA"
     polyA_site      2582
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
     regulatory      2656..2661
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
                     /note="hexamer: AATAAT"
     polyA_site      2682
                     /gene="SLCO6A1"
                     /gene_synonym="CT48; GST; OATP-I; OATP6A1; OATPY"
ORIGIN      
        1 aggagaaacg ttcgctctgg aggcttgggc ggcaagagcc ccttgtggcc accgagtcct
       61 ccgacgccct cgccaggctg gcctttgggt tggcccaggc aggacgggca gccgagagca
      121 ctcgggccgc gtcgccagga gccgcccagg gtgagccatg ttcgtaggcg tcgcccggca
      181 ctctgggagc caggatgaag tctcaagggg agtagagccg ctggaggccg cgcgggccca
      241 gcctgctaag gacaggaggg ccaagggaac cccgaagtcc tcgaagcccg ggaaaaaaca
      301 ccggtatctg agactacttc cagaggcctt gataaggttc ggcggtttcc gaaaaaggaa
      361 aaaagccaag tcctcagttt ccaagaagcc gggagaagtg gatgacagtt tggagcagcc
      421 ctgtggtttg ggctgcttag tcagcacctg ctgtgagtgt tgcaataaca ttcgctgctt
      481 catgattttc tactgcatcc tgctcatatg tcaaggtgtg gtgtttggtc ttatagatgt
      541 cagcattggc gattttcaga aggaatatca actgaaaacc attgagaagt tggcattgga
      601 aaagagttac gatatttcat ctggcctggt agcaatattt atagcattct atggagacag
      661 aaaaaaagta atatggtttg tagcttcctc ctttttaata ggacttggat cacttttatg
      721 tgcttttcca tccattaatg aagaaaataa acaaagtaag gtaggaattg aagatatttg
      781 cgaagaaata aaggttgtca gtggttgcca gagcagtggt atatcattcc aatcaaaata
      841 cctgtctttc ttcatccttg ggcagactgt gcagggaata gcaggaatgc ctctttatat
      901 ccttggaata acctttattg atgagaatgt tgctacacac tcagctggta tctatttagg
      961 tattgcagaa tgtacatcaa tgattggata tgctctgggt tatgtgctag gagcaccact
     1021 agttaaagtc cctgagaata ctacttctgc aacaaacact acagtcaata atggtagtcc
     1081 agaatggcta tggacttggt ggattaattt tctttttgcc gctgtcgttg catggtgtac
     1141 attaatacca ttgtcatgct ttccaaacaa tatgccaggt tcaacacgga taaaagctag
     1201 gaaacgtaaa cagcttcatt tttttgacag cagacttaaa gatctgaaac ttggaactaa
     1261 tatcaaggat ttatgtgctg ctctttggat tctgatgaag aatccagtgc tcatatgcct
     1321 agctctgtca aaagctacag aatatttagt tattattgga gcttctgaat ttttgcctat
     1381 atatttagaa aatcagttta tattaacacc cactgtggca actacacttg caggacttgt
     1441 tttaattcca ggaggtgcac ttggccagct tctgggaggt gtcattgttt ccacattaga
     1501 aatgtcttgt aaagccctta tgagatttat aatggttaca tctgtgatat cacttatact
     1561 gcttgtgttt attatttttg tacgctgtaa tccagtgcaa tttgctggga tcaatgaaga
     1621 ttatgatgga acagggaagt tgggaaacct cacggctcct tgcaatgaaa aatgtagatg
     1681 ctcatcttca atttattctt ctatatgtgg aagagatgat attgaatatt tttctccctg
     1741 ctttgcaggg tgtacatatt ctaaagcaca aaaccaaaaa aagatgtact acaattgttc
     1801 ttgcattaaa gaaggattaa taactgcaga tgcagaaggt gattttattg atgccagacc
     1861 cgggaaatgt gatgcaaagt gctataagtt acctttgttc attgctttta tcttttctac
     1921 acttatattt tctggttttt ctggtgtacc aatcgtcttg gccatgacgc gggttgtacc
     1981 tgacaaactg cgttctctgg ccttgggtgt aagctatgtg attttgagaa tatttgggac
     2041 tattcctgga ccatcaatct ttaaaatgtc aggagaaact tcttgtattt tacgggatgt
     2101 taataaatgt ggacacacag gacgttgttg gatatataac aagacaaaaa tggctttctt
     2161 attggtagga atatgttttc tttgcaaact atgcactatc atcttcacta ctattgcatt
     2221 tttcatatac aaacgtcgtc taaatgagaa cactgacttc ccagatgtaa ctgtgaagaa
     2281 tccaaaagtt aagaaaaaag aagaaactga cttgtaactg gatcatcatt gtgattgcag
     2341 atcatttgag gatcagagtg tgaaaacgag tttctctttt acagattctc caagatttgt
     2401 ttctgtgccc aactttcaga agaggaaaat cacacattat gtttacataa gtagcaaaaa
     2461 tatatttatg gtgatctgca ttttcataat aaagtgtcct attgtgaaac atttctgata
     2521 atgtttttaa tgtatgtaga atttttagga tttactggga gaattaaagt ttaataattt
     2581 tagattattt acatttcttc ttaatattct gctgtctaga aatattaaaa attatacaac
     2641 taggaaataa agtaaaataa taacattcaa agccactttg aa
//
