LOCUS       XM_011528792            7056 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier organic anion transporter
            family member 4A1 (SLCO4A1), transcript variant X1, mRNA.
ACCESSION   XM_011528792
VERSION     XM_011528792.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000020.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011528792.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7056
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
     gene            1..7056
                     /gene="SLCO4A1"
                     /gene_synonym="OATP-E; OATP1; OATP4A1; OATPE; OATPRP1;
                     POAT; SLC21A12"
                     /note="solute carrier organic anion transporter family
                     member 4A1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 35 ESTs, 411 long SRA reads, and
                     96% coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:28231"
                     /db_xref="HGNC:HGNC:10953"
                     /db_xref="MIM:612436"
     CDS             148..2454
                     /gene="SLCO4A1"
                     /gene_synonym="OATP-E; OATP1; OATP4A1; OATPE; OATPRP1;
                     POAT; SLC21A12"
                     /codon_start=1
                     /product="solute carrier organic anion transporter family
                     member 4A1 isoform X1"
                     /protein_id="XP_011527094.1"
                     /db_xref="GeneID:28231"
                     /db_xref="HGNC:HGNC:10953"
                     /db_xref="MIM:612436"
                     /translation="MPLHQLGDKPLTFPSPNSAMENGLDHTPPSRRASPGTPLSPGSL
                     RSAAHSPLDTSKQPLCQLWAEKHGARGTHEVRYVSAGQSVACGWWAFAPPCLQVLNTP
                     KGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFV
                     SYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCAD
                     STSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFYTAAILGP
                     AAGYLIGGALLNIYTEMGRRTELTTESPLWVGAWWVGFLGSGAAAFFTAVPILGYPRQ
                     LPGSQRYAVMRAAEMHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTFILLCLAG
                     ATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLR
                     GSAVIKFCLFCTVVSLLGILVFSLHCPSVPMAGVTASYGGSLLPEGHLNLTAPCNAAC
                     SCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLSSGFGHAT
                     AGKCTSTCQRKPLLLVFIFVVIFFTFLSSIPALTATLRCVRDPQRSFALGIQWIVVRI
                     LGGIPGPIAFGWVIDKACLLWQDQCGQQGSCLVYQNSAMSRYILIMGLLYKAPLLRIH
                     PTLDGKCSFCGRWNWRVRRADCTYKYTYMSVHMFLYKRVTVKLFLILRYISLVIHGVN
                     SWYQLPCVPQSHMLKPRPQDGCVWRQGL"
     polyA_site      7056
                     /gene="SLCO4A1"
                     /gene_synonym="OATP-E; OATP1; OATP4A1; OATPE; OATPRP1;
                     POAT; SLC21A12"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agagcgtgga gcgctgcgcg gcgcggcggc cgggccctcg agacggggac ggacacacca
       61 gcccctcgga taccacttgg ccactcccgc tgaggccact cccactgcgt ggctgaagcc
      121 tcgaggtcac caggcggagg cgcggagatg cccctgcatc agctggggga caagccgctc
      181 accttcccca gccccaactc agccatggaa aacgggcttg accacacccc acccagcagg
      241 agggcatccc cgggcacacc cctgagcccc ggctccctcc gctccgctgc ccatagcccc
      301 ctggacacca gcaagcagcc cctctgccag ctctgggccg agaagcatgg cgcccggggg
      361 acccatgagg tgcggtacgt ctcggccggg cagagcgtgg cgtgcggctg gtgggccttc
      421 gcaccgccgt gcctgcaggt cctcaacacg cccaagggca tcctgttctt cctgtgtgcg
      481 gccgcattcc tgcaggggat gactgtgaat ggcttcatca acacagtcat cacctccctg
      541 gagcgccgct atgacctgca cagctaccag agcgggctca tcgccagctc ctacgacatt
      601 gccgcctgcc tctgcctcac cttcgtcagc tacttcgggg gctcagggca caagccgcgc
      661 tggctgggct ggggcgtgct gcttatgggc acggggtcgc tggtgttcgc gctgccccac
      721 ttcacggctg gccgctatga ggtggagttg gacgcgggtg tcaggacgtg ccctgccaac
      781 cccggcgcgg tgtgtgcgga cagcacctcg ggcctgtccc gctaccagct ggtcttcatg
      841 ctgggccagt tcctgcatgg cgtgggtgcc acacccctct acacgctggg cgtcacctac
      901 ctggatgaga acgtcaagtc cagctgctcg cccgtctaca ttgccatctt ctacacagcg
      961 gccatcctgg gcccagctgc cggctacctg attggaggtg ccctgctgaa tatctacacg
     1021 gaaatgggcc gacggacgga gctgaccacc gagagcccac tgtgggtcgg cgcctggtgg
     1081 gtcggcttcc tgggctctgg ggccgctgct ttcttcaccg ccgttcccat ccttggttac
     1141 cctcggcagc tgccaggctc ccagcgctac gcggtcatga gagcggcgga aatgcaccag
     1201 ttgaaggaca gcagccgtgg ggaggcgagc aacccggact ttgggaaaac catcagagac
     1261 ctgcctctct ccatctggct cctgctgaag aaccccacgt tcatcctgct ctgcctggcc
     1321 ggggccaccg aggccactct catcaccggc atgtccacgt tcagccccaa gttcttggag
     1381 tcccagttca gcctgagtgc ctcagaagct gccaccttgt ttgggtacct ggtggtgcca
     1441 gcgggtggtg gcggcacctt cctgggcggc ttctttgtga acaagctcag gctccggggc
     1501 tccgcggtca tcaagttctg cctgttctgc accgttgtca gcctgctggg catcctcgtc
     1561 ttctcactgc actgccccag tgtgcccatg gcgggcgtca cagccagcta cggcgggagc
     1621 ctcctgcccg aaggccacct gaacctaacg gctccctgca acgctgcctg cagctgccag
     1681 ccagaacact acagccctgt gtgcggctcg gacggcctca tgtacttctc actgtgccac
     1741 gcagggtgcc ctgcagccac ggagacgaat gtggacggcc agaaggtgta ccgagactgt
     1801 agctgtatcc ctcagaatct ttcctctggt tttggccatg ccactgcagg gaaatgcact
     1861 tcaacttgtc agagaaagcc cctccttctg gttttcatat tcgttgtaat tttctttaca
     1921 ttcctcagca gcattcctgc actaacggca actctacgat gtgtccgtga ccctcagaga
     1981 tcctttgccc tgggaatcca gtggattgta gttagaatac tagggggcat cccggggccc
     2041 atcgccttcg gctgggtgat cgacaaggcc tgtctgctgt ggcaggacca gtgtggccag
     2101 cagggctcct gcttggtgta ccagaattcg gccatgagcc gctacatact catcatgggg
     2161 ctcctgtaca aggctcccct gctgaggatt catcccacct tggatggaaa atgcagtttt
     2221 tgtgggagat ggaactggag ggtacggagg gctgactgca catacaaata tacatacatg
     2281 agtgtacata tgttcttata taaacgtgtc acagtaaaat tgttcctcat cttgcgttac
     2341 atttccctcg ttattcatgg ggtgaacagc tggtatcaac tgccttgcgt cccccagagc
     2401 catatgttga agccccggcc ccaggatggc tgtgtttgga ggcagggcct ttaggagatg
     2461 attatgtgcg gggtcataag ggtgggtgca ggtcccacag gactggtgtc cttaagagac
     2521 ctctgccatc cggagctcct tatggccaaa cccttcccac tcgctgagcc ctgcagcccc
     2581 agggcctctc tgaggactta gtttcaggtg ggtcagatca gaacccccgg gtggtcccca
     2641 gcactgagga tggacgccac cctcgccctc cggtgctcac agtctgcagc gcctgccagg
     2701 agttctcaaa acccaatgcg tcggtcaaga tcccccccaa attagggtac aatccggtgc
     2761 tggtgacatt ttgatttgct aagtaaggag ataaaacaca gccataagga gaggggacct
     2821 gggctcacca ggacgcttgt gtggagctca ctgctgtgac tgctgggcca gggaggggca
     2881 tggggggggc acagagggcc aagttgggaa atgatgggga gcagggggtg cagggagaaa
     2941 cttcccgagg gaggtgacag aagggagtgc aggaacagac cctagaggga gtacaggggc
     3001 tctggggagc cagggaagtg gatcgccact cagaagggag tggggaggac gaggaacctc
     3061 accaggtccc acctttgcca tgttcatcag gagtccggtt catcaggagt catcagaggt
     3121 gggtggagct agggtcagga tgaggctcgg gcatgctggg cagtgccggc ttccagtgac
     3181 ctgcctcctc cgggtgtcac tgggacacac ttccaacaag caggacttag cacagggcag
     3241 atgccacatc cctgaccggg ttattagaga ccacgacact gcccagccca ccttctgacc
     3301 aggttataag agaccacgac actgcccagc ccaccttctc gccactcttc tcaagggctg
     3361 ccctggcggg aaccccgcat ggccaggaac tggcctctgc ctacggtcgg caagaaaccg
     3421 gatgctcagc cctggccttc aaggactgga atcctgccaa gggccacgtg agccaaccaa
     3481 gaggggacga caccctgtag cacctggact gcagacacat cagagaccca gctccgtggt
     3541 gcctgaattc tggacccaca aaggctttga catagtcaac gtgtgctgcg aaaagtcact
     3601 aaattctggg gcagtttgtt ctgcagccat agctaaccaa cacactgggc aacagcacaa
     3661 aacaagggcc agtcctttgc cgctcacctg ttctccatgg gcatggacct caccccccag
     3721 gctcgtctat ggcagtggct ggcacttggc cactgggctg gggcaggagg gaatcagggt
     3781 ggaaggtgcc agccatctcc tcctagagtc ccacgagacc atttcggcgg atgcctgccc
     3841 tcaagccctc tgctcagagc tacgtcccgt ggtcccagtg agtggtgggc gaggcaggaa
     3901 ccagccgtgc tcccagctga aggaggtgtt ctggtaccgg agtgtgggtg ttggggcaca
     3961 gctggccgca cctgtcagag gcgtgtggca ctgagcatcc gtgtggaggt gtccatgggg
     4021 ccctcgggga gactcatggg agctgtcagc ctgcgggctg agctgagatt ggtcagggga
     4081 gctcatccgg gaaggctggg cagatccaaa tggaacccgg ggacctcagg actgagcagg
     4141 tggaagaggc tgcgtcctca catcagggaa aggggggaag agcccaggga cactgggtgg
     4201 agaagggatg agagggaggc ggcacacgcg gtctggccac caagggtggt gcaccctctc
     4261 tgctgccagt ggtcaagatg gtctctgact cacagatgac gattccaagg gtctgagcgg
     4321 ccctgtgtgt tccccgatgt ctcacagtga caaatgggca gaggcagggg ctgtggactg
     4381 acagcatccc ccagttcgta ggtcgaagcc ccagcaccca gtgtgatggt gttaagagct
     4441 gggacctcag ggaggtgact agggtgagat gagggggtga gggtggcccc ccgatgggat
     4501 tcgtagccct gtaacagagg aagagaccaa gctcctctct cctctatgtg ctgacacgac
     4561 tagaagacag ccgtctgcag accaaggaaa ggaccctccc tgggagccca gccttgctcg
     4621 tgggcttcgg gactccagaa tgtgggtaag gcacgtccgt tgtttgagcc gccaagctat
     4681 ggttctgtga tggccgccga gctgacggag gctgtagagt ttcgactccg gtctgggggc
     4741 tccaaggact gtcccgctcc atgccctgcc cccaccctgg atgccaggaa ggaagagaaa
     4801 cgccccgagc tgcagagagg acagagagag ggaaggaaga ggaccagcat gttcgcacag
     4861 ggcacacagt ggaggctccc gcccaggatg gagggcaggt attccaggga gcggccccca
     4921 aagcgactgg gtgtatgctg ggctgctcat cggcattgca aggcatccat ctccctgccg
     4981 gcagtgagac ttcgtggtgc gtgatggatg aggccaccaa gcccagattc ccttcccagg
     5041 tccaggaggg cccctccagt gggcagcccg ggctgccggc cacccacgcg ggctctgcca
     5101 cccctcaggc agctcccaag agctgcgggg tctctgcagc tcttgagctc tgctgccctc
     5161 gcctcgatct aagctcccct tgccttcccc attgacaatc cgcctggctc tgactcaggc
     5221 ccagggagga gacaggagca gatggctgac agggacagtt gggacacagg ggcagagagg
     5281 aagcagtctg gttgcagcct ggtcccggcc ccagcccccc aggcctgatg acccagcctc
     5341 tgtgtgactc agtgcaggga gcgtgtggct cctggccctg ccacagaggc cagaaggcat
     5401 ctgcagatgc ccacacaggc cccccgcttc tccgggatca cgggcgcacc cagcctggtg
     5461 ggcacatggg ccctggatac gccctcggct gcatgctggc ctgggtcctg gatgcctccc
     5521 acagccagcc cctgtcctcc cacgtcctgg gaggagcccc tgggattagc caggaaggtg
     5581 ccggccacag ggcccggctg cctgtgggga ggagaaagac atgcatcctg ggagagggag
     5641 aggcaggcag gagtcctcca agcccacttg gttttccctc gagagatttt ccacggctgc
     5701 tgggatgagg gctgcggggg cctcctgtgt gctgtgcact aaatgttctt caagagtcag
     5761 acgccaggag cagctggaaa cgtcaaattt tctggttgtt ggaccagttc ctcttattct
     5821 tctgtgcatt taaaaattat cactgaattc ggccggctcg ccagcgcacg cctataatcc
     5881 cagcactttg ggaggctgag gcaagcagat cgcttgagcc caggagcttg agaccaaact
     5941 gggcaacgta gcgaaaccct gtctctgtaa aaaaaaaata caaaacatta gccgggcatg
     6001 gtggcgtgcg cctgtagtcc cagctacttg ggaggctgag gtgggaggat cgcctaagcc
     6061 tgggaggtca aggctgtcgt gagccatgaa tgtgccactg cactctggcc tgggtggcag
     6121 agtgagactc tttctcaaaa taataataag aagaattcct acaacccaac aatgaaagga
     6181 tgatccaatt taaaaatggg caaaggattt gacttttatt tcatcacaaa agacatagaa
     6241 aaggccaacg agcccaggag aagatgctca agattttccc actcagggaa gtgcaaacca
     6301 aagccacagc gctgaccgta tcaaaaacaa aagcaacaaa caaacaaaac cagaaaacga
     6361 cacgtcgtgg agaacttgga atcctcacac actatgggtg ggaatgtaaa acggtaaaat
     6421 ggcacagccg ctttggaaaa cagttttgcg gttcatcaaa aagttaacca tggaattagc
     6481 agatgaccca gcaattccac acctagtatc tacccaagag aaatgaagac atatgtccac
     6541 ataaagacat gcatacaaat gttcacggca atgttgctca taacagtcaa aaagtgcacc
     6601 agcccgaatg tcaactggct gatgagtagg taaatcagcg tgggctgtcc acacagtggg
     6661 tcttgcttgg ccgtcaatca gaaagaatga agccctgcgc tatggtgtgc aggtgcgcat
     6721 ggaccttgaa acatgctcag tgaaagaagc cagacacaaa aggccacgtg ttttgtgatt
     6781 cttttgtaag aaatgtccag aatggacaaa tctgtagaga cagaaaatgg actagtggtg
     6841 ccaggggctg ggggaaggtg aggcgggagc gactgtcatg ggtgcagggc gttttggtgc
     6901 agtgatgaaa tgttctggag ttagataacg gtgatggttg cacaactctg tgaacatgct
     6961 taaaaaaccg aattgtacac tttaaagggt gaatatttgg ggatgtgact tatatctcag
     7021 taaagctatt attaaataca tccatccatg cattca
//
