LOCUS       NM_003043               6500 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens solute carrier family 6 member 6 (SLC6A6), transcript
            variant 1, mRNA.
ACCESSION   NM_003043
VERSION     NM_003043.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6500)
  AUTHORS   Baliou,S., Kyriakopoulos,A.M., Goulielmaki,M., Panayiotidis,M.I.,
            Spandidos,D.A. and Zoumpourlis,V.
  TITLE     Significance of taurine transporter (TauT) in homeostasis and its
            layers of regulation (Review)
  JOURNAL   Mol Med Rep 22 (3), 2163-2173 (2020)
   PUBMED   32705197
  REMARK    GeneRIF: Significance of taurine transporter (TauT) in homeostasis
            and its layers of regulation (Review).
            Review article
REFERENCE   2  (bases 1 to 6500)
  AUTHORS   Ansar,M., Ranza,E., Shetty,M., Paracha,S.A., Azam,M., Kern,I.,
            Iwaszkiewicz,J., Farooq,O., Pournaras,C.J., Malcles,A., Kecik,M.,
            Rivolta,C., Muzaffar,W., Qurban,A., Ali,L., Aggoun,Y.,
            Santoni,F.A., Makrythanasis,P., Ahmed,J., Qamar,R., Sarwar,M.T.,
            Henry,L.K. and Antonarakis,S.E.
  TITLE     Taurine treatment of retinal degeneration and cardiomyopathy in a
            consanguineous family with SLC6A6 taurine transporter deficiency
  JOURNAL   Hum Mol Genet 29 (4), 618-623 (2020)
   PUBMED   31903486
REFERENCE   3  (bases 1 to 6500)
  AUTHORS   Manzoor,U. and Dar,T.A.
  TITLE     Protein kinases as regulators of osmolyte accumulation under stress
            conditions: An overview
  JOURNAL   Front Biosci (Landmark Ed) 25 (7), 1386-1411 (2020)
   PUBMED   32114438
  REMARK    GeneRIF: Protein kinases as regulators of osmolyte accumulation
            under stress conditions: An overview.
            Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6500)
  AUTHORS   Hellinen,L., Sato,K., Reinisalo,M., Kidron,H., Rilla,K.,
            Tachikawa,M., Uchida,Y., Terasaki,T. and Urtti,A.
  TITLE     Quantitative Protein Expression in the Human Retinal Pigment
            Epithelium: Comparison Between Apical and Basolateral Plasma
            Membranes With Emphasis on Transporters
  JOURNAL   Invest Ophthalmol Vis Sci 60 (15), 5022-5034 (2019)
   PUBMED   31791063
REFERENCE   5  (bases 1 to 6500)
  AUTHORS   Miyamoto,Y., Liou,G.I. and Sprinkle,T.J.
  TITLE     Isolation of a cDNA encoding a taurine transporter in the human
            retinal pigment epithelium
  JOURNAL   Curr Eye Res 15 (3), 345-349 (1996)
   PUBMED   8654117
REFERENCE   6  (bases 1 to 6500)
  AUTHORS   Patel,A., Rochelle,J.M., Jones,J.M., Sumegi,J., Uhl,G.R.,
            Seldin,M.F., Meisler,M.H. and Gregor,P.
  TITLE     Mapping of the taurine transporter gene to mouse chromosome 6 and
            to the short arm of human chromosome 3
  JOURNAL   Genomics 25 (1), 314-317 (1995)
   PUBMED   7774940
REFERENCE   7  (bases 1 to 6500)
  AUTHORS   Gregor,P., Hoff,M., Holik,J., Hadley,D., Fang,N., Coon,H. and
            Byerley,W.
  TITLE     Dinucleotide repeat polymorphism in the human taurine transporter
            gene (TAUT)
  JOURNAL   Hum Mol Genet 3 (12), 2263 (1994)
   PUBMED   7881434
REFERENCE   8  (bases 1 to 6500)
  AUTHORS   Ramamoorthy,S., Leibach,F.H., Mahesh,V.B., Han,H., Yang-Feng,T.,
            Blakely,R.D. and Ganapathy,V.
  TITLE     Functional characterization and chromosomal localization of a
            cloned taurine transporter from human placenta
  JOURNAL   Biochem J 300 (Pt 3) (Pt 3), 893-900 (1994)
   PUBMED   8010975
REFERENCE   9  (bases 1 to 6500)
  AUTHORS   Jhiang,S.M., Fithian,L., Smanik,P., McGill,J., Tong,Q. and
            Mazzaferri,E.L.
  TITLE     Cloning of the human taurine transporter and characterization of
            taurine uptake in thyroid cells
  JOURNAL   FEBS Lett 318 (2), 139-144 (1993)
   PUBMED   8382624
REFERENCE   10 (bases 1 to 6500)
  AUTHORS   Uchida,S., Kwon,H.M., Yamauchi,A., Preston,A.S., Marumo,F. and
            Handler,J.S.
  TITLE     Molecular cloning of the cDNA for an MDCK cell Na(+)- and
            Cl(-)-dependent taurine transporter that is regulated by
            hypertonicity
  JOURNAL   Proc Natl Acad Sci U S A 89 (17), 8230-8234 (1992)
   PUBMED   1518851
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7424. doi:
            10.1073/pnas.90.15.7424-b.. PMID: 8346265]
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK303649.1, BM149397.1,
            U09220.1, AC090941.2, AB209172.1 and CA448606.1.
            
            On Aug 13, 2020 this sequence version replaced NM_003043.5.
            
            Summary: This gene encodes a multi-pass membrane protein that is a
            member of a family of sodium and chloride-ion dependent
            transporters. The encoded protein transports taurine and
            beta-alanine. There is a pseudogene for this gene on chromosome 21.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, May 2013].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853565.19991.1,
                                           SRR11853561.20310.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000622186.5/ ENSP00000480890.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AK303649.1         31-173
            144-455             BM149397.1         144-455
            456-2158            U09220.1           161-1863
            2159-3899           AC090941.2         1234-2974           c
            3900-6498           AB209172.1         3730-6328
            6499-6500           CA448606.1         17-18               c
FEATURES             Location/Qualifiers
     source          1..6500
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p25.1"
     gene            1..6500
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /note="solute carrier family 6 member 6"
                     /db_xref="GeneID:6533"
                     /db_xref="HGNC:HGNC:11052"
                     /db_xref="MIM:186854"
     exon            1..242
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            243..284
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            285..524
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..2158
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /note="isoform a is encoded by transcript variant 1;
                     sodium- and chloride-dependent taurine transporter; solute
                     carrier family 6 (neurotransmitter transporter, taurine),
                     member 6"
                     /codon_start=1
                     /product="sodium- and chloride-dependent taurine
                     transporter isoform a"
                     /protein_id="NP_003034.2"
                     /db_xref="CCDS:CCDS33705.1"
                     /db_xref="GeneID:6533"
                     /db_xref="HGNC:HGNC:11052"
                     /db_xref="MIM:186854"
                     /translation="MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKW
                     SSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIG
                     QYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
                     HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKW
                     DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF
                     YLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNS
                     GTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF
                     IMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEG
                     GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSW
                     AVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC
                     QTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM"
     exon            525..659
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            660..894
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1027
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1162
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1266
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1391
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1504
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1642
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1745
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1846
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..2017
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..6500
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6474..6479
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /note="hexamer: AATAAA"
     polyA_site      6500
                     /gene="SLC6A6"
                     /gene_synonym="HTRDC; TAUT"
                     /note="major polyA site"
ORIGIN      
        1 gagagctgcc tgctcagaca acagacacgc gaggtcagga agaagccgct tataaattac
       61 cgcttccttc gcgccgccgc caacgccgag ccccgaggac cgcaagccca gaggacaagc
      121 tgcgccaaga gggagtgcgg agcgttcacc cagcgggtca gagagcgagc gggcaggcag
      181 cccccggccg gcggaacccg gcacagccga gcagagcgcg ggcggcgccg cagccacccc
      241 agatccagaa ccagaaccac agcccttctg aggagctccc aaacaaagca aggagatggc
      301 caccaaggag aagctgcagt gtctgaaaga tttccacaag gacatcctga agccctcacc
      361 agggaagagc ccaggcacgc ggcctgagga cgaggctgag ggaaaacctc cgcagaggga
      421 gaagtggtct agcaagatcg actttgtgct ctctgtggct ggcggcttcg tgggcttggg
      481 caacgtctgg cgcttcccgt acctctgcta caagaatggt ggaggtgcgt ttctcatacc
      541 gtattttatt ttcctgtttg ggagcggcct gcctgtgttt ttcttggaga tcatcatagg
      601 ccagtacacc tctgaagggg gcatcacctg ctgggaaaag atctgcccct tgttctctgg
      661 tatcggctat gcctccgttg taattgtgtc cctcctgaat gtctactaca tcgtcatcct
      721 ggcctgggcc acatactacc tgttccagtc cttccagaag gagctgccct gggcacactg
      781 caaccacagc tggaacacac ctcactgcat ggaggacacc atgcgcaaga acaagagtgt
      841 ctggatcacc atcagctcca ccaacttcac ctcccctgtc atcgagttct gggagcgcaa
      901 cgtgctgagc ttgtcccctg gaatcgacca cccaggctct ctgaaatggg acctcgctct
      961 ctgccttctt ttagtctggc tagtgtgttt cttctgcatc tggaagggcg tcaggtccac
     1021 tgggaaggtc gtctacttca cagccacttt tccattcgcc atgctcctgg tgctgctggt
     1081 ccgagggctg acgctgccgg gcgcgggcgc aggcatcaag ttctatctgt atcctgacat
     1141 cacccgcctt gaggacccac aggtgtggat tgacgctggg actcagatat tcttctctta
     1201 tgccatctgc ctgggggcta tgacctcgct ggggagctac aacaagtaca agtataactc
     1261 gtacagggac tgtatgctgc tgggatgcct gaacagtggt accagttttg tgtctggctt
     1321 cgcaattttt tccatcctgg gcttcatggc acaagagcaa ggggtggaca ttgctgatgt
     1381 ggctgagtca ggtcctggcc tggccttcat tgcctaccca aaagctgtga caatgatgcc
     1441 gctgcccaca ttttggtcca ttcttttttt tattatgctt ctcttgcttg gactggatag
     1501 ccagtttgtt gaagttgaag gacagatcac atccttggtt gatctttacc catccttcct
     1561 aaggaagggt tatcgtcggg aaatcttcat cgccttcgtg tgtagcatca gctacctgct
     1621 ggggctgacg atggtgacgg agggtggcat gtatgtgttt cagctctttg actactatgc
     1681 agctagcggt gtatgccttt tgtgggttgc attctttgaa tgttttgtta ttgcctggat
     1741 atatggaggt gataaccttt atgatggtat tgaggacatg attggctatc ggcccgggcc
     1801 ctggatgaag tacagctggg ctgtgatcac tccagttctc tgtgttggat gtttcatctt
     1861 ctcgctcgtc aagtacgtac ccctgaccta caacaaaaca tacgtgtacc ccaactgggc
     1921 cattgggctg ggctggagcc tggccctttc ctccatgctc tgcgttccct tggtcatcgt
     1981 catccgcctc tgccagactg aggggccgtt ccttgtgaga gtcaagtacc tgctgacccc
     2041 aagggaaccc aaccgctggg ctgtggagcg cgagggagcc acaccttaca actctcgcac
     2101 cgtcatgaac ggcgctctcg tgaaaccgac ccacatcatt gtggagacca tgatgtgagc
     2161 tctctcgggt cgacggggcc ggcggctttc ctgctgttta ctaacattag attctcatag
     2221 gaccaggttt acagagcttt atatttgcac taggattttt ttttttttgt aattgtcaca
     2281 gaaaatgtaa ttgtgggtat gtgtgcgtgc gtgtgtgtgt gtgtgtgtat cgtgtgtgtg
     2341 tgttttgttt tgatttgggg gatattttgt acaaaaagaa aacccacggg aagatgtccg
     2401 tggagaggca gagctttcat actgaattag atgtatttta tgggaatttg gtaaattttt
     2461 ctttgtattt ttttttttac atataagtat atatacactt agagattgtc atatactttt
     2521 accacttgaa ttgatcttct tgccagcaat agatctcatt ttcaaaagca attcttcggt
     2581 gctgtgtagc tggcagaaag ttctgtccag taaacgcagg atggaatttt cctgggactc
     2641 tacacccatc ttaaggtggt ataccttcca aatcctggtt cagatggaag aaatagcagg
     2701 agagaggacc cattagctgg cagacccagg gggaagaaag gagggctgtg aggagatacc
     2761 tcattaaact tggcttagtg aagaagagag atgccaaagg aatgaaccaa cccttcacat
     2821 aaaggagact ggctgaagct gaatgaggag gccctatagc agaagtctga ttctaagagc
     2881 agtagaaact tgtaccagaa gcaaaatccc acttttaatt ttgagatggt gagtggatag
     2941 tcagtagacc gtcagaacca ctggccagag agggagctgc tagagatcca agaaggctgg
     3001 caggagtgag gctcacaact cagcctcgca agaggtggca gaggcacagg aggccacagt
     3061 ccttcctggg gcattccagg cagagaagga gcagaggctc tcccggcagg agctggggtc
     3121 tcagggctca gatgagtctg ttgcatttga atggggtcat agcaggttct ggtcattccc
     3181 caagcaacat ctcagcatct cttaaagttg cctgcaggaa tgaagcatga catacctgtt
     3241 gagggactag gggagtggtg gggaggtgag tggaccaaag gatataggcc ccaggcatgc
     3301 agatgggccc ggtgtcgggg aggggtgctt tctttcctca tctccccact ccccactctc
     3361 agcctgggag actcctgcca agccctcatt aaagatgcca ccctgggctg ccctggcacc
     3421 tagcaaggca caccaagaac agcttttgag tctgtatcct ccactggggg aagtgctccc
     3481 agttcagaac aagggcagcc cgtggtgctg acctaggata taacaaagct cttcacttca
     3541 aaacccctgc aatagctggg tttacagaca tttaccacct gcggacccaa aagagaaggc
     3601 ctaggagagt tttctagaag gttgggattg tcagggtcct ggcccctcag aactggcttg
     3661 atcaagggcc ttatgtggag cagaggttgt ctctgaacca ggagagaagg tactatacct
     3721 ttcaaatccc cagggcagac acacccccac ccagccccta tttggaccta aactgtgcca
     3781 tttgaacagt cacttccaag ctcagtctaa atgaaaccga aacgtgacca cgcacaaagg
     3841 cagtcactgc ctcgaggggt gcagaccgca gaattttcac agcaggggct cttggaaccc
     3901 tggaaacccc cttcttaaat ttgggaggag gagtatgcct ttggtgtccc cctcccaagg
     3961 ggcaattctg aaccccatct ttggcaggca tacatatttc actgtttcca aagctatcta
     4021 ctctgccaaa caacacccag tcctattcca aactctcaac gattctatct tgttcctgtt
     4081 tttctatgta tttatggttg ccgtttgtgt ctgatttgat tttactgttt tttccctgat
     4141 tttatggagt agcattgtga cctgttttcc tttgtcttat ataactttag taaactaacc
     4201 actgtcaatg attgagggca ggtggcacgt ggggaagagg ggacttggca cgcagtggct
     4261 acctgggcat ttgtggtcat ttcagtttcc atctccccag cgggggctcc ctgggtgaaa
     4321 ggccacagta ttttgggttg gtaggcaaat tgcaacattc tggacatggc ctgaggaagg
     4381 cctcttctta taagattctc agaccaaatt ctagaccaaa gacacaggca gaccaagtcc
     4441 ccaggccccg cctggaagga agtcgttcct caactctccc caaggcacct gtctccaatc
     4501 agagccctct cgcccagcca gccctggctc tgtgtgcaga gcatagctct gcgagtacct
     4561 gtgtaataat gctcaacctt catgtctccg tataaacgaa actttccatg agagctcatg
     4621 actctggtcc acctgtctat agagaatggg caaagtcctt cacctgcttt ctgcttggga
     4681 tgggtcagaa atgctgatgc ccgcacatag cccagccagc cagatctgga aaggaagcga
     4741 gggggttgtt taaatcaatt ttttaagatg aagaagtggg agacactgcg ttgagatggg
     4801 ccatgctagg gccacagaga tttcctgacg gtcagggaga gaagggcctc cagggtcccc
     4861 taacccaacg cccttgttgt aaatgaggta actgaggctc agggaggcac tgtgagccag
     4921 gaatggattt tcttgaaaca gctctagctg caggttctcc gaggtaggtg cagggaatgg
     4981 tgagtgtcta accagggcta catccagcaa catcctcaag gtcttcctga caaccaaaga
     5041 caagccttta tggaaaagga aatgcgctcc cctccatgtt cagggatgag gggagcagca
     5101 gcagccacac tcccaccatc ctcacagaat tcctggaccc atgcggtggc tccgtgagct
     5161 gggtgactcc agcctcacct gcacacccca gccctgcacg gggccctcct tcctcccagc
     5221 agcccttggt gagctaggaa ttgagatccc tgtttgtgaa agagggaact gaggtgcaga
     5281 gaagccagag gtgtgccaga tccttaggca ggatttagat gaagtcgccc tggctccaga
     5341 ctgaccccga ggctctgcgg ggagtttcca ggcagcagga agtggccttg gatgctctcc
     5401 ttccaggaca gcataacccc tgggccatgt gcagctcctt cactgccccc tggatcccca
     5461 gcataccccc aaagacagtg gggaaacaca aggggagagc acagcatggc ccctccagcc
     5521 cacttcaggg cactcttgta tcacccgggt accgccacac tggtccccca cccagccagc
     5581 atctcccagc acagcccctc tccctgggga aatgctctgg gtagccagtc taaaggcaga
     5641 ggcacctaac tgctccccgc agcccacccc acccaagatt cagacacaag ccaggaaagg
     5701 acccaagaga aaatccttca aggtggcctg aggtcccatc cctccctcag acccatgtgg
     5761 tcccaggcca ggctgcctgg gacacggtaa ataccactgt gtgcaaaaat cgaagtacaa
     5821 aaccacaaga ctaaacaaaa caaacccaga gagccaaact tgtagaggtg ggcagtccag
     5881 aaagcagggg gcagccctcc ccctttcctt ctctccctga tcctcagaat atatattgtt
     5941 gtaataggaa gcatttttgc attgttctct tgtgggtgtc actacagaca tgttctggcg
     6001 tgttctccga gggatggagc atcctgttat atatttgact tcaaattgag atgttggctt
     6061 catttttttt ttttacccaa ttaatctccc aatccctagc aactgtgact ctgtatttag
     6121 cacaagagaa agctgagaat gtgggtcttg cctccttcca gaaatatgtc tggctcatca
     6181 ggacattttt ttaaaacttc aaaatatttt taagatattt taaactttta taaaaaaaaa
     6241 atcaaccaac aagagacttt tctgaggagg aacatttgta tttgaacaag atccttggtg
     6301 tgtagttcag tcttgcagta tacaagcttt tgtgtataaa tgttttatga tatgattccc
     6361 tgtattttgc aggggttttt ttctcttttg ctttttagat aaatatgtat atcaatattt
     6421 taaattcatc tttgcttttt ttagaggagt ttgtaatcac cttataacat gaaaataaac
     6481 atttcctttt taacatccaa
//
