LOCUS       XM_011521010            3387 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier family 6 member 12
            (SLC6A12), transcript variant X1, mRNA.
ACCESSION   XM_011521010
VERSION     XM_011521010.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011521010.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3387
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..3387
                     /gene="SLC6A12"
                     /gene_synonym="BGT-1; BGT1; GAT2"
                     /note="solute carrier family 6 member 12; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 26 ESTs, 59 long SRA reads, 16 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 16 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6539"
                     /db_xref="HGNC:HGNC:11045"
                     /db_xref="MIM:603080"
     CDS             556..2400
                     /gene="SLC6A12"
                     /gene_synonym="BGT-1; BGT1; GAT2"
                     /codon_start=1
                     /product="sodium- and chloride-dependent betaine
                     transporter isoform X1"
                     /protein_id="XP_011519312.1"
                     /db_xref="GeneID:6539"
                     /db_xref="HGNC:HGNC:11045"
                     /db_xref="MIM:603080"
                     /translation="MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKME
                     FVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQ
                     GSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNF
                     WNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLL
                     LAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLF
                     RLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAG
                     FVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLG
                     LDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQL
                     FDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGL
                     CLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFR
                     KRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETHL"
ORIGIN      
        1 agctcagtga ttagcctgtg gagcaggaaa gtccagcgat gggcagctgg tcacggcagt
       61 gggtgaaagc aggggtggtc atctgacgag gggaggggaa gcaggtggtg cccagcaagg
      121 tggaaggaga agtggacagg agaaacctcg gggcattccc gagggcccag gaactgcaat
      181 aaatgatcac aggtgagggg ttcctgcccg ctgcctgccg gctgagcgtg acgagctggg
      241 tgccaggcgc ctcccaggag gaagctgtct tggctttggg cggtggatgc tatgggtgtg
      301 cttgtacccg aggggggcac tcaggggagt tgcaggcagc caccagctga gaccggcact
      361 cacggggtgt gaaggactac agagagagcc aggttttggt gccatgcaca cagggaaact
      421 tagagttcag agagggggtg tgatttgcct gaggtcacac agcaagttag agacccagct
      481 ccacgactca ttgtcttggc tttggccctc gtcatcctgc ccacccagcg gggcttccca
      541 acccaccaca cagccatgga cgggaaggtg gcagtgcaag agtgtgggcc tcctgcagtc
      601 tcctgggtcc ccgaggaggg agagaagttg gaccaggaag acgaggacca ggtgaaggat
      661 cggggccaat ggaccaacaa gatggagttt gtgctgtcag tggccgggga gatcattggg
      721 ctgggcaatg tctggaggtt tccctatctc tgctacaaaa acggaggtgg agccttcttc
      781 atcccctact tcatcttctt ctttgtctgc ggcatcccgg tgttcttcct ggaggtggcg
      841 ttgggccaat acaccagcca agggagtgtc acagcctgga ggaagatctg ccccctcttc
      901 cagggcattg gtctggcatc tgtggtcatc gagtcatatt tgaatgtcta ctacatcatc
      961 atccttgcct gggctctctt ctacctgttc agctccttca cttctgagct gccctggacg
     1021 acctgcaaca acttttggaa cacagagcat tgcacggact ttctgaacca ctcaggagcc
     1081 ggcacagtga ccccatttga gaattttacc tcacctgtca tggaattctg ggagagacga
     1141 gttctgggca tcacctcggg catccatgac ctgggctccc tgcgctggga gctggccctg
     1201 tgcctcctgc tcgcctgggt catctgctat ttctgcatct ggaagggggt caagtccaca
     1261 ggcaaggtgg tttatttcac agccacgttt ccgtacctga tgcttgtcat tttgctgatc
     1321 agaggtgtca cccttcccgg agcctaccag ggcatcatct actacttgaa gccagatttg
     1381 ttccgcctca aggaccctca ggtgtggatg gatgcgggca cccagatctt cttctccttt
     1441 gccatctgcc aggggtgcct gacagccctg ggcagctaca acaagtatca caacaactgc
     1501 tacaaggact gcatcgccct ctgcttcctg aacagtgcca ccagctttgt ggctgggttt
     1561 gttgtcttct ccatcctggg cttcatgtcc caagagcaag gggtgcccat ttctgaagtg
     1621 gccgagtcag gtcctgggct ggccttcatc gccttcccca aggctgtgac tatgatgccc
     1681 ttatcccagc tgtggtcctg cctgttcttt atcatgctca tattcctagg gctggacagc
     1741 cagtttgtct gtgtggagtg cctggtgaca gcctccatag acatgttccc caggcagctc
     1801 cggaagagcg ggcggcgcga gctcctcatc ctcaccatcg ccgtcatgtg ctacctgata
     1861 gggcttttcc tggtcaccga gggcgggatg tacatcttcc agctgtttga ctactatgct
     1921 tccagtggca tatgcctgct gttcctgtca ttgtttgaag tggtctgcat aagctgggtg
     1981 tatggggcgg accgtttcta tgacaacatt gaggacatga ttggctaccg gccatggccc
     2041 ctggtgaaga tctcctggct cttcctgacc cctggacttt gcctggccac tttcctcttc
     2101 tccttgagca agtacacccc cctcaagtac aacaacgtct atgtgtaccc gccctgggga
     2161 tactccattg gctggttcct ggctctgtcc tccatggtct gtgtcccact cttcgtcgtc
     2221 atcaccctcc tgaagactcg gggtcctttc aggaagcgtc tgcgtcagct catcacccct
     2281 gactccagtc tgccacagcc caagcaacat ccctgcttgg atggcagtgc tggccggaac
     2341 tttgggccct ccccaacaag ggaaggactg atagccgggg agaaggagac ccatttgtag
     2401 ggtgtggcca gaggccaggc ggctcctaag ccgggaacct aggtcagggc caccctccat
     2461 tctcagcgga cagcctctgc ctctgtctcc tgccacaatc ctgctgggaa cctctggaga
     2521 gccacaggca cccccagctg gaggccagac tcctctcttg tgctagctgg agcagctcct
     2581 tcccctttgc tgataacacc accactggga cgtgccatgt tgggacgcca ctccctgtgg
     2641 gaaggcacca tcgtttttat aaaggggggt ctttttggag gccgccatct gattgcaaca
     2701 cctcgagtta tgaggattcc actgtgggga tgcctcttgt tagagcgtac tgcatttgta
     2761 cacggggaga ggagctataa ttggaacgca cactgccgtc caatgtggag agcctgatgg
     2821 gacaataccc tgttggaagt gacaactgaa cacactgtgt tggatcggag gttccgttag
     2881 gggatccttc cttaggctta acgacagagg caagcctttg catgccgtca gtctggagtt
     2941 tcctccgagt ctctcatggc atctccagct cctgccctag ttccgcactg ttcttgcagt
     3001 gtttcatcaa ctcctggagc attggaatgg aaggggcttg ggagatgatt cctagacttc
     3061 acaaacactc ggcatgcctc cctgcactgt ccgttcctct gcccaaggcc gatattgcta
     3121 actgatcaca gattctttcc cacctcacaa tccttccgaa tgtgctccag gcagcaccat
     3181 ttgccatcct gcttctaacg caaacccctg acttcatgga tgaggaacct ggagaccaaa
     3241 gagacaaagg gactttttca agttcacatg gggaccccct tcttgggggc cagagatatg
     3301 actaaaacct tatctccttg tgctcaggcc agtgtcttcc cattaacccc ctgccttagt
     3361 taacaagtgt gtatggattg ccttcca
//
