LOCUS       XM_017027158            3112 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier family 5 member 5 (SLC5A5),
            transcript variant X3, mRNA.
ACCESSION   XM_017027158
VERSION     XM_017027158.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017027158.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..3112
                     /gene="SLC5A5"
                     /gene_synonym="NIS; TDH1"
                     /note="solute carrier family 5 member 5; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 1 EST, 20 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 12 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6528"
                     /db_xref="HGNC:HGNC:11040"
                     /db_xref="MIM:601843"
     CDS             151..1815
                     /gene="SLC5A5"
                     /gene_synonym="NIS; TDH1"
                     /codon_start=1
                     /product="sodium/iodide cotransporter isoform X3"
                     /protein_id="XP_016882647.1"
                     /db_xref="GeneID:6528"
                     /db_xref="HGNC:HGNC:11040"
                     /db_xref="MIM:601843"
                     /translation="MCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCG
                     TLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTD
                     VFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVV
                     GGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFY
                     TDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV
                     TVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI
                     SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAA
                     RCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTT
                     VLCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTG
                     NKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL"
ORIGIN      
        1 gctcccgtaa gccccaaggc gacctccagc tgtcagcgct gagcacagcg cccagggaga
       61 gggacagaca gccggctgca tgggacagcg gaacccagag tgctgggcgt gccgtcggag
      121 gcctatcgct atggcctcaa gttcctctgg atgtgcctgg gccagcttct gaactcggtc
      181 ctcaccgccc tgctcttcat gcccgtcttc taccgcctgg gcctcaccag cacctacgag
      241 tacctggaga tgcgcttcag ccgcgcagtg cggctctgcg ggactttgca gtacattgta
      301 gccacgatgc tgtacaccgg catcgtaatc tacgcaccgg ccctcatcct gaaccaagtg
      361 accgggctgg acatctgggc gtcgctcctg tccaccggaa ttatctgcac cttctacacg
      421 gctgtgggcg gcatgaaggc tgtggtctgg actgatgtgt tccaggtcgt ggtgatgcta
      481 agtggcttct gggttgtcct ggcacgcggt gtcatgcttg tgggcgggcc ccgccaggtg
      541 ctcacgctgg cccagaacca ctcccggatc aacctcatgg actttaaccc tgacccgagg
      601 agccgctata cattctggac ttttgtggtg ggtggcacgt tggtgtggct ctccatgtat
      661 ggcgtgaacc aggcgcaggt gcagcgctac gtggcttgcc gcacagagaa gcaggccaag
      721 ctggccctgc tcatcaacca ggtcggcctg ttcctgatcg tgtccagcgc tgcctgctgt
      781 ggcatcgtca tgtttgtgtt ctacactgac tgcgaccctc tcctcctggg gcgcatctct
      841 gccccagacc agtacatgcc tctgctggtg ctggacatct tcgaagatct gcctggagtc
      901 cccgggcttt tcctggcctg tgcttacagt ggcaccctca gcacagcatc caccagcatc
      961 aatgctatgg ctgcagtcac tgtagaagac ctcatcaaac ctcggctgcg gagcctggca
     1021 cccaggaaac tcgtgattat ctccaagggg ctctcactca tctacggatc ggcctgtctc
     1081 accgtggcag ccctgtcctc actgctcgga ggaggtgtcc ttcagggctc cttcaccgtc
     1141 atgggagtca tcagcggccc cctgctggga gccttcatct tgggaatgtt cctgccggcc
     1201 tgcaacacac cgggcgtcct cgcgggacta ggcgcgggct tggcgctgtc gctgtgggtg
     1261 gccttgggcg ccacgctgta cccacccagc gagcagacca tgagggtcct gccatcgtcg
     1321 gctgcccgct gcgtggctct ctcagtcaac gcctctggcc tcctggaccc ggctctcctc
     1381 cctgctaacg actccagcag ggcccccagc tcaggaatgg acgccagccg acccgcctta
     1441 gctgacagct tctatgccat ctcctatctc tattacggtg ccctgggcac gctgaccact
     1501 gtgctgtgcg gagccctcat cagctgcctg acaggcccca ccaagcgcag caccctggcc
     1561 ccgggattgt tgtggtggga cctcgcacgg cagacagcat cagtggcccc caaggaagaa
     1621 gtggccatcc tggatgacaa cttggtcaag ggtcctgaag aactccccac tggaaacaag
     1681 aagccccctg gcttcctgcc caccaatgag gatcgtctgt ttttcttggg gcagaaggag
     1741 ctggaggggg ctggctcttg gaccccctgt gttggacatg atggtggtcg agaccagcag
     1801 gagacaaacc tctgaggaca gggccagccg cgggactgac accctgggat ggaacctcag
     1861 gatgggccaa acccagacaa cgggcccatg gccttgggct ctgattggct ggattgcctt
     1921 gtatgcaaat gagttcagga ctacaatacc ctaccctatg gggaggccct gcctccggga
     1981 ggtcattttt taaatccagc cccttgcttc aaccgtcccc agtattagac gctgcagccc
     2041 tgacggctcc ccccaaataa ggctgggttt ttctctctct cttttttttt tttttttttt
     2101 tttgagacag ggtcatgctc tgtcacccag gctggagtgc agtggtgtga tctcggctca
     2161 ctgcaacctc tgcctcccag gctcaagtga ttctcctgcc tcagcctctt gagtagctgg
     2221 gattgtaggt gcccaccacc atgcccagcc aactttttgt atttttagta gagacagggt
     2281 ttcaccatgt tggtcaggct ggtctcgaac tcctgacctc aagtgatcca cctgcctcgg
     2341 cctcccaaag tgctgggtta caggcgtaag ctaccatgcc cagcctaccg tttttctcaa
     2401 tctataatag aaagccacca cgcccaggta atttttgtaa ttttgtattt ttgtagagac
     2461 ggggttttgc catgttggcc aggctggtct caaactcctg atctcaggtg atcctcctgc
     2521 cttggcctcc caaagggctg ggattacagg ggtgagccac cgcgccccac ctctttctta
     2581 ttttcttcct gggattgggg aggggatgat tcagacccca catggcctcc aaccttggcc
     2641 cacacacctg ccatggctcc catcatcctg agcatgctag cgtcccctcc tcacctgaca
     2701 atggaggctc tcgaattggg ttgtgtcccc ccaaaattta tgtctaccca gaacctcaga
     2761 acatgagctt acttggaaat agggtctttg caggtgtaac tggttaaatt aaaagaggta
     2821 ttactggagg aggatggatg aatccagtga ctggttcctc atatgaagta gagaagagat
     2881 gcagagaaac acatggggaa gatgccacgt gaagacagag gcagtggttg gatcaatgca
     2941 tctacgagtc ggagaaccca aggattgcca gcaacaacca gaaatcagga ggggggcatg
     3001 agatgcatta tttcttagag cctttagagg gaacatggcc ctactgacac cttgatgtca
     3061 gacttctggc tgctagaact gtcagagaat aaatttctgt tgtttgatgc ca
//
