LOCUS       XM_011534258            7971 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier family 4 member 7 (SLC4A7),
            transcript variant X4, mRNA.
ACCESSION   XM_011534258
VERSION     XM_011534258.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011534258.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7971
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..7971
                     /gene="SLC4A7"
                     /gene_synonym="NBC2; NBC3; NBCN1; SBC2; SLC4A6"
                     /note="solute carrier family 4 member 7; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 19 ESTs, 1398 long SRA reads, 7 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 16 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:9497"
                     /db_xref="HGNC:HGNC:11033"
                     /db_xref="MIM:603353"
     CDS             259..3930
                     /gene="SLC4A7"
                     /gene_synonym="NBC2; NBC3; NBCN1; SBC2; SLC4A6"
                     /codon_start=1
                     /product="sodium bicarbonate cotransporter 3 isoform X4"
                     /protein_id="XP_011532560.1"
                     /db_xref="GeneID:9497"
                     /db_xref="HGNC:HGNC:11033"
                     /db_xref="MIM:603353"
                     /translation="MEADGAGEQMRPLLTRVTSRGPDEEAVVDLGKTSSTVNTKFEKE
                     ELESHRAVYIGVHVPFSKESRRRHRHRGHKHHHRRRKDKESDKEDGRESPSYDTPSQR
                     VQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSK
                     PYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVR
                     EALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSA
                     SNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSISRLTSRSSQ
                     ESQRQAPELLVSPASDDIPTVVIHPPEEDLEAALKGEEQKNEENVDLTPGILASPQSA
                     PGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLER
                     PIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHD
                     VAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGST
                     PTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFL
                     YCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLV
                     FEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALI
                     CIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITA
                     HNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKT
                     KRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPL
                     GDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLG
                     VCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGL
                     SVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPL
                     WKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDL
                     MPESKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDKPVSV
                     KISFEDEPRKKYVDAETSL"
     polyA_site      7971
                     /gene="SLC4A7"
                     /gene_synonym="NBC2; NBC3; NBCN1; SBC2; SLC4A6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agttctagct tcaggttcca cgccgcggcc tcgctctcct actaaagcca gcccagcagt
       61 cgcagcgcgc acacgcacgc cccgcgtctc ccgcgcccgg cgcccggctc tccccacgcg
      121 cgcacacctc gcgcacggac gcacccacgt ttgtcctcgc gcgccggggg ctcggcggcg
      181 gcggcagggg cagcggcaga agcaggcaga ccgcgcgggg cagtaccgta gcggccgtca
      241 cgggctggcc ggccggccat ggaggctgat ggggccggcg agcagatgag accgctactc
      301 acccgggtaa cgagcagggg tcctgatgaa gaagctgttg tggatcttgg caaaactagc
      361 tcaactgtga acaccaagtt tgaaaaagaa gaactagaaa gtcatagagc tgtatatatt
      421 ggtgttcacg tcccgtttag taaagagagt cgtcggcgtc ataggcatcg cggacacaaa
      481 catcaccacc ggagaagaaa agataaagaa tcagataaag aagatggacg ggaatctcct
      541 tcttatgata caccatccca gagagttcag tttatccttg gtactgaaga tgatgatgaa
      601 gaacatattc cccatgatct cttcacggaa atggatgaac tgtgttacag agatggagaa
      661 gaatatgaat ggaaagaaac tgctagatgg ctgaaatttg aagaggatgt tgaagatggc
      721 ggtgaccgat ggagtaaacc ttatgtggca actctctctt tgcacagtct ttttgaacta
      781 aggagttgca tcctcaatgg aacagtcatg ctggatatga gagcaagcac tctagatgaa
      841 atagcagata tggtattaga caacatgata gcttctggcc aattagacga gtccatacga
      901 gagaatgtca gagaagctct tctgaagaga catcatcatc agaatgagaa aagattcacc
      961 agtcggattc ctcttgttcg atcttttgca gatataggca agaaacattc tgaccctcac
     1021 ttgcttgaaa ggaatgggga aggcctttca gcctcccgcc actctttgcg aacaggtctg
     1081 tctgcctcaa acctttcctt gagaggagaa tcacctttat ctcttcttct tggtcatctt
     1141 cttccttctt caagagctgg aacccctgca ggctcaaggt gtacaacccc agtacccacc
     1201 cctcaaaaca gtcctccttc tagccctagc atcagccgcc tgacctccag aagttcccaa
     1261 gagagtcagc gtcaggcccc agaactactg gtttcacctg ccagtgatga tattcccaca
     1321 gtagtaattc atccgcctga ggaagactta gaagcagcgc tgaaaggcga ggagcagaag
     1381 aatgaggaaa atgttgactt aactccaggt attttggcct ctccccagtc tgctcctgga
     1441 aacttggaca atagtaaaag tggagaaatt aaaggtaatg gaagtggtgg aagcagagaa
     1501 aatagtactg ttgacttcag caaggttgat atgaatttca tgagaaaaat tcctacgggt
     1561 gctgaggcat ccaacgtcct ggtgggcgaa gtagactttt tggaaaggcc aataattgca
     1621 tttgtgagac tggctcctgc tgtcctcctt acagggttga ctgaggtccc tgttccaacc
     1681 aggtttttgt ttttgttatt gggtccagcg ggcaaggcac cacagtacca tgaaattgga
     1741 cgatcaatag ccactctcat gacagatgag attttccatg atgtagctta taaagcaaaa
     1801 gacagaaatg acctcttatc tggaattgat gaatttttag atcaagtaac tgtcctacct
     1861 ccaggagagt gggatccttc tatacgcata gaaccaccaa aaagtgtccc ttctcaggaa
     1921 aagagaaaga ttcctgtgtt tcacaatgga tctaccccca cactgggtga gactcctaaa
     1981 gaggccgctc atcatgctgg gcctgagcta cagaggactg gacggctttt tggtggtttg
     2041 atacttgaca tcaaaaggaa agcacctttt ttcttgagtg acttcaagga tgcattaagc
     2101 ctgcagtgcc tggcctcgat tcttttccta tactgtgcct gtatgtctcc tgtaatcact
     2161 tttggagggc tgcttggaga agctacagaa ggcagaataa gtgcaataga gtctcttttt
     2221 ggagcatcat taactgggat tgcctattca ttgtttgctg ggcaacctct aacaatattg
     2281 gggagcacag gtccagttct agtgtttgaa aaaattttat ataaattctg cagagattat
     2341 caactttctt atctgtcttt aagaaccagt attggtctgt ggacttcttt tttgtgcatt
     2401 gttttggttg caacagatgc aagcagcctt gtgtgttata ttactcgatt tacagaagag
     2461 gcttttgcag cccttatttg catcatattc atctacgagg ctttggagaa gctctttgat
     2521 ttaggagaaa catatgcatt taatatgcac aacaacttag ataaactgac cagctactca
     2581 tgtgtatgta ctgaacctcc aaaccccagc aatgaaactc tagcacaatg gaagaaagat
     2641 aatataacag cacacaatat ttcctggaga aatcttactg tttctgaatg taaaaaactt
     2701 cgtggtgtat tcttggggtc agcttgtggt catcatggac cttatattcc agatgtgctc
     2761 ttttggtgtg tcatcttgtt tttcacaaca ttttttctgt cttcattcct caagcaattt
     2821 aagaccaagc gttactttcc taccaaggtg cgatcgacaa tcagtgattt tgctgtattt
     2881 ctcacaatag taataatggt tacaattgac taccttgtag gagttccatc tcctaaactt
     2941 catgttcctg aaaaatttga gcctactcat ccagagagag ggtggatcat aagcccactg
     3001 ggagataatc cttggtggac cttattaata gctgctattc ctgctttgct ttgtaccatt
     3061 ctcatcttta tggatcaaca aatcacagct gtaattataa acagaaagga acacaaattg
     3121 aagaaaggag ctggctatca ccttgatttg ctcatggttg gcgttatgtt gggagtttgc
     3181 tctgtcatgg gacttccatg gtttgtggct gcaacagtgt tgtcaataag tcatgtcaac
     3241 agcttaaaag ttgaatctga atgttctgct ccaggggaac aacccaagtt tttgggaatt
     3301 cgtgaacagc gggttacagg gctaatgatt tttattctaa tgggcctctc tgtgttcatg
     3361 acttcagtcc taaagtttat tccaatgcct gttctgtatg gtgttttcct ttatatggga
     3421 gtttcctcat taaaaggaat ccagttattt gaccgtataa aattatttgg aatgcctgct
     3481 aagcatcagc ctgatttgat atacctccgt tatgtgccgc tctggaaggt ccatattttc
     3541 acagtcattc agcttacttg tttggtcctt ttatgggtga taaaagtttc agctgctgca
     3601 gtggtttttc ccatgatggt tcttgcatta gtgtttgtgc gcaaactcat ggacctgtgt
     3661 ttcacgaaga gagaacttag ttggcttgat gatcttatgc cagaaagtaa gaaaaagaaa
     3721 gaagatgaca aaaagaaaaa agagaaagag gaagctgaac ggatgcttca agatgatgat
     3781 gatactgtgc accttccatt tgaaggggga agtctcttgc aaattccagt caaggcccta
     3841 aaatatagtc ctgataaacc tgtgagtgtg aaaataagtt ttgaagatga accaagaaag
     3901 aaatacgtgg atgctgaaac ttcattatag aattgaacca agaggcatta tacatataga
     3961 tatatacata tgtaatgtgt gcgtatcatg tcactatata taagaatatt gtatgtcatg
     4021 ctgtttatgt gtgactaccg ggtttttaaa agtagtgtct ggagtttgta atgagcaccg
     4081 tggagactat gtatttaatg aaatgctctc tttgaagtga ggtacatggt tcttaactat
     4141 tcaaatattt attctgttag aaaaaaaaat tttctgtttt gcaatagaag gatgtggaga
     4201 aatgctttca gtctactttt cttaaatctc tgttcatcag tggcaattcg taaaaacctt
     4261 aagtgatact ttgtttatat gtttataatt tttaggtgtt tcctgaaatt ttcacatatt
     4321 atttcacttt tgttagtgct ttatgggaag aatagggagt ctataccagt gctgtgggaa
     4381 aaatggtaac atttcagggc ttctctattt gtgtttcatt tctgtagatg tccatcgtgt
     4441 ttcactaact ggcgttttct tagccataga gatgactgta gaacaataga aactttaata
     4501 atgatagttt ttaactttta tgtttaaatt ttttttaaat cttaaaacct tcatatctag
     4561 gtatccattg tgacagacaa gtaaaattgc aggtgatttg ataattaagc acccatacca
     4621 tttataactt ctgaatttaa aaagttatac aatgccagtt tgcaatagtt gattttgatg
     4681 cctttgtaga atattttttc tgaatcctta tgctctttta aagccaatga ttcccactct
     4741 gttctctgcc ttgtctctct ttgtcttaaa atgctttagt ttccatcagg ttcaagttct
     4801 tgactattat tctcttataa gtagtaggcg taaataatca ggagttagaa ttctctcaga
     4861 agggtctatg atcagtatta ctttattaag aattaccttt cattttctct ttatgttatt
     4921 ctttcacttt tgtagattac atttaatagc ttgttacctg tgattttatt ttaaaatatt
     4981 tattttgata tgatgcttaa atattatata aacatttgga aaagtaacaa atagagtaaa
     5041 ttgttaatgt aaatagttgg tgcttacttt catttatgtt tattatctta aagcaattga
     5101 tagattttac atctttgata taaagcactg ccatatttat attttaaaag gaaattagac
     5161 attttatatg tagctcagat taatgacatt tttattttgt gtattagttt ttgcttttct
     5221 gagcttttta aagtctaaca aatcttttta gtcatctttt atatactttt agttccacat
     5281 gaaataaatg ttgttaagcc tgtaggactg gatgaatggg gttgtgaaac tgatttgaca
     5341 agagaataat ttacaaaaat caaatgagta ttgagaagcc acagaaatat caaaaatggt
     5401 gacatcacta ttaggatgaa aattttatga aattccaatg ctccctttaa ccatataatt
     5461 aaattacaaa ggtatacata attaatctaa taaaggatca tgaggaatgc caaaagctga
     5521 aattttagca agtctggtgt tttaaattca ttataaacta tttattaact aatgtaatgt
     5581 cctcctctaa gaccatattg taagagtctt gttaaaatga tggattcaac ttctgcctcg
     5641 gatgagaggt tggaaatgta gctgcttttc tttagaaaat atgtagctgt catcatttgg
     5701 tactgcctaa aaagagttag actctattgg caattgatag agtattaccc acggtgctta
     5761 ttattgttta tgagcttcca ttgtaatgat tcctttttat ttgtagcagc ataattattt
     5821 ccaaagaccc cagtatttgc tgctattttt aaaactcccc tgatgtacct gaacaagagg
     5881 atttcctcac atcatttcct tgtgtctgga catcaggggt aacaactgta cttactttac
     5941 aggaagaaat tttaaaactg aaaactacct gggatcatag tgtttctgtg attttattta
     6001 attgtgtata gtaattatcc agtgccagaa aaaccgtcac ttgcaaaata ctttgcactc
     6061 aaaatgtttt tacaatgctt ctaaatgtta ctggtttctg ctttcttttg actacttgac
     6121 tgacaaaatg atctgactac tccatttaag agcaaaggta actcatgttt aggtaattaa
     6181 ctgcttgttt taagtgatta tatttcttcc actgtttttg aaaaataatc aaagatagca
     6241 ttcattgaga gacagtgaca gatataattt actacatata ttgattttta aataaagttg
     6301 ccttaaataa gtgtatgtaa gcagtagtag ttgctatgta ctgatttacc tcaaggtgca
     6361 aaataattaa acctgtacat attccattta caaaataaat tcagccctgc actttcttta
     6421 gatgccttga tttccagaat ggagcttagt gctactgaat accctggcca cagagccacc
     6481 tcaggatatt cttttctcca ccctagttta tttatttata gatatctgtt tacaaagtct
     6541 gtagtaaatc ctgatgctga ccatctgaaa tgtacttttt ttctgaatgc tgtttcaatc
     6601 taaaatagca gcttttgaga aaacaatgat gtaaattcct tatgataaaa ggatgattct
     6661 atatattctt taatgatatt aaatatgccg aagccaagca cacagtcttt ctaaagtgtg
     6721 tgtatgtttg tgtgaatgtg aatgatactg atcttatatc tgttaaaagt tgttttaaaa
     6781 agctgtggca tcccattgtt catatttgcc aagtcttctg taaagatgtc taggacgaaa
     6841 tattttatgt gctaatgcat gtatttgtaa accagatttg tttaccactc aaaattaact
     6901 tgttttcttc atccaaaaaa gtttatttct tccacgtact taaattttct gtgtgggtat
     6961 aatatagctt tctaattttt ttctttcaca aaggcaggtt caaaattctg ttgaaagaaa
     7021 aatgctttct gaaactgagg tataacacca gagcttgctg tttaaaggat tatatgatgt
     7081 acatcagttc tataaatgtg ctcagcagtt taacatgtga atcctgtttt aaagtgctca
     7141 gatttcaact gtgtaagcca ttgatataac gctgtaatta aaaatgttta tatgaaataa
     7201 cttaatgttt taaatttatt tatgtagatc acatcatttt tatcgtatgc agtgcaaata
     7261 tgtgaaatgt cttttggttt attccaacaa ttatttattt tagaaagtaa gtttaaagac
     7321 tttaaggaca ttcaaagttt aaaatagtgt tcaaattgca aaatttggca atcttcatat
     7381 aaattggttt cttttctaac ttttcaaaaa ctaacattaa atgtcaatta taggaaaaca
     7441 tagttggaaa tgtaatcatc caaagatcat ttttaaaatg aaatttaatt agcacatatt
     7501 gaacatttga cttaattgtt aaaccccagt tttgttttgt ttttttaatc agatttttgc
     7561 acactgatta gtttttgtgt tgtggctttt gttgctttat tattcaaggt tttttttttt
     7621 tttcttcccc atgggggaga ttgtcttcca atgtttaact acgtttaaat aaataaaaat
     7681 tgaattttat tgttcattta tataaaatct gataccttga tgtaatttca caatacagtt
     7741 ccaattttta tggcttttat aattacaatg atattttctt ctataataaa atccaaagta
     7801 aacatttaaa ttgtagaact gatatttttc atttatatga agtataagcc tctactgggt
     7861 ctatattgtg aatcatcctg cctttcaaat ttgtttcata attgttagat gaaaactatt
     7921 tttttggaga tgttactgaa gttgattgag caataaaagt ctacttaatt a
//
