LOCUS       XM_047435280            6172 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier family 46 member 1
            (SLC46A1), transcript variant X4, mRNA.
ACCESSION   XM_047435280
VERSION     XM_047435280.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6172
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6172
                     /gene="SLC46A1"
                     /gene_synonym="G21; HCP1; hPCFT; HsPCFT; PCFT"
                     /note="solute carrier family 46 member 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 12 ESTs, 469 long SRA reads, and 99% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 14 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:113235"
                     /db_xref="HGNC:HGNC:30521"
                     /db_xref="MIM:611672"
     CDS             242..1267
                     /gene="SLC46A1"
                     /gene_synonym="G21; HCP1; hPCFT; HsPCFT; PCFT"
                     /codon_start=1
                     /product="proton-coupled folate transporter isoform X4"
                     /protein_id="XP_047291236.1"
                     /db_xref="GeneID:113235"
                     /db_xref="HGNC:HGNC:30521"
                     /db_xref="MIM:611672"
                     /translation="MQEVETLTSHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLV
                     LASLGLLLQALVSVFVVQLQLHVGYFVLGRILCALLGDFGGLLAASFASVADVSSSRS
                     RTFRMALLEASIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAMTLYAAFCFGETL
                     KEPKSTRLFTFRHHRSIVQLYVAPAPEKSRKHLALYSLAIFVVITVHFGAQDILTLYE
                     LSTPLCWDSKLIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFA
                     FATITPLMFTGCWKRLILTSSSSSFPRAPDLPGPEDRGQEEQSEHQATGGLQLEAQPT
                     AGQATLV"
ORIGIN      
        1 gctcttccag ctctgccttg agtacccgat gacctcgttt cctcagcggt agatagcgat
       61 ggttaatatt ggctagcctg tagagttatc gggagaccaa cgcacaaaaa gggtttaata
      121 ccgtgcccag cacataggcc cgctcaccac gcagtatctg tggcaccgct tcagcgccga
      181 cctcggctac aatggcaccc gccaaagggg gggctgcagc aaccgcagcg cggaccccac
      241 catgcaggaa gtggagaccc ttacctccca ctggaccctc tacatgaacg tgggcggctt
      301 cctggtgggg ctcttctcgt ccaccctgct gggagcttgg agcgacagtg tgggccgccg
      361 cccgctgcta gtgctggcct cgctgggcct gctgctccag gccctagtgt ccgtttttgt
      421 ggtgcagctg cagctccacg tcggctactt cgtgctgggt cgcatccttt gtgccctcct
      481 cggcgacttc ggtggccttc tggctgctag ctttgcgtcc gtggcagatg tcagctccag
      541 tcgcagccgc accttccgga tggccctgct ggaagccagc atcggggtgg ctgggatgct
      601 ggcaagcctc ctcgggggcc actggctccg ggcccagggt tatgccaacc ccttctggct
      661 ggccttggcc ttgctgatag ccatgactct ctatgcagct ttctgctttg gtgagacctt
      721 aaaggagcca aagtccaccc ggctcttcac gttccgtcac caccgatcca ttgtccagct
      781 ctatgtggct cccgccccag agaagtccag gaaacattta gccctctact cactggccat
      841 cttcgtggtg atcactgtgc actttggggc ccaggacatc ttaacccttt atgaactaag
      901 cacacccctc tgctgggact ccaaactaat cggctatggt tctgcagctc agcatctccc
      961 ctacctcacc agcctgctgg ccctgaagct cctgcagtac tgcctggccg atgcctgggt
     1021 agctgagatc ggcctggcct tcaacatcct ggggatggtg gtctttgcct ttgccactat
     1081 cacgcctctc atgttcacag gatgctggaa aaggctgatc ctcacctcga gttccagcag
     1141 tttccccaga gcccctgatc tgcctggacc agaagacaga gggcaagagg agcaaagtga
     1201 acaccaagca actggaggtc tgcagctgga agcccagccc acagcaggac aagcaactct
     1261 tgtctaaggg cagtgctctc tttggacgag gtagtcaaga gagaccaagg caccacccca
     1321 tccacagctg acccagcctc tgtctaggat ctagaatcat aacccacaca ggcccactgc
     1381 aggacaggtg gcagaggagc tatttgggac aggagtcagt tctccctttc tgctatccat
     1441 cacttataac cccacaggcc agaggagagg tcctgagaga ggtgacactt cagggaccag
     1501 aggcagcacg agggctggca tctctccttc cagcccaaac tgcacagccc caaccaggtt
     1561 cccaacacgt gtagcagtca tcagccattc cttaacaatg aatgtggtac ctggttagtg
     1621 ccagccttgg gaaggaggga gggaggtaag aggggcttgg tgatctctgg aggaagagtg
     1681 ttgcctttgc tgtggttggg gaatcgatcc ttggctatgg cctacccact cccctggctg
     1741 aagagtgcca atcattacaa atcagcttca gcaaactgaa acaaaccttc tggtgccttg
     1801 ggctttgggg ccctctgttt tcctgctccc agtctgcctg ccatacgtta gacaacagaa
     1861 gctgctgggc tgggcaggag ccctgagctg cctggtggat tggtaccaag tggggccagc
     1921 cagggcttct actgactcgc tgtgcaacct tgagcaagcc ccactaggaa cggctagatc
     1981 agcaatgccc caaattgttg aatcgtggtg atcacatttg gatggacaag ttaggaaact
     2041 tagctgattc tctgagatac ttcccacttc ctcatacatt ctacaatgag atgcctctct
     2101 tcatgggcct ggggaaagga tgaatgagtg tggctggact tttgaccttt aatgtccctg
     2161 agcagttctt ggcccttggg gagaagtagg gggaggatct ggctgactca gccccaaccg
     2221 aggggtagca gctgcagccc agccaagcag aacaccctgg ccctacagac ctgtgtctga
     2281 gcaggctttg gaggaaaggc cacttctgag tcctctgtct caggagaagc caggcctagg
     2341 tgcttgacct ggtgatctga gctgtgtttg tcctagtatg ggtggcagtc acctctgaac
     2401 acactggcct tggcttagag gaggcttgtg acttcagctg ttccagctgg ggctggatgc
     2461 tggactctga ttccctcaga gagacagaag atcgggcaga ggtcaaccag aaggccacac
     2521 agggcagtgg acaacagtgg agggtatacc aaatagaaat aaaacgcagg aaacctctct
     2581 gaatactgcc cttggggacc tcaggaggga gtgggactga ttggagacaa agagccagaa
     2641 atcatcccct ggagatactc agacactgta ttgttattgg cgctgtcctg tgagggcagt
     2701 gtccaggctg ccctgcttgt catatccatg ccctggctct ggccccggtg agcacttgtg
     2761 ctgcatgagg aaaggaggat caggtggggt caaaaccaaa gcatcgaggc tggcactggc
     2821 caagacagac tctggcaggg aggggagtgg aaggaaggag ccccaaacct ggagtgagac
     2881 ctttgacttt ctgatgatgt ggccaagaac taggagtcac ctggccagca cagccaagag
     2941 tggggctggg ggcgcagcca gctttaaggt gtcaacacct ggcccttgcg gggaaagagc
     3001 cttcagcagc ccccacggcc tggagcctgg gtttattgga gggtgctttc ttaccctctg
     3061 aacccagtgg aggagggggc aatgggatat tcctgctctg tatggcctct gggtcagctt
     3121 tttgttgcaa aatcctatcc cccgctgcta gattctttga agcaagggag aagcaatagc
     3181 ccagcctcag aatgattctc aggaaagcaa ttccactgcc agtggactgg gtgccaggag
     3241 gcctaggtct ggatctgggg ctgccactaa tgacaggaaa gtgggcttat cctcaacctt
     3301 tctgagcctc agtgtcatta tctgtaaaat ggggatgata ataccaggta gagttgctct
     3361 gatgactgga gaccatggag cggagtgttt gggaaatggc aaagatttgt gagggcttcg
     3421 tgctttagag atttgctacc cttaaccacc agcatcagct cacctgggaa tctgtaagaa
     3481 atgcagagtc ctaggcccca ccccagatct cctgatttta acaacattcc caggtgactt
     3541 ggatgcatgt taaagttgga gaagctgccc taagtgacaa ccctttgcct tttcaggact
     3601 ttgcctcttt ccacagagct gcaggttctg tctaggctgc ttttactgcc atgggggctg
     3661 cctggtccct gagtaagcag tgggtagccc tggatggctg aggggctggg gaagccagct
     3721 gggccagacc aggaaggagc ctgaggcaca gcaccaaggc atggggtagg gtgggctttg
     3781 aggcacggcc tccccatgcc cagacccagg cccaaacagg aggctcctgt gcaccagcaa
     3841 gtgcagcaaa gctggctgca gtgacaagga agtcagaggg agggctggtt tgcctcaacc
     3901 ctcgccctgg atgtggcaaa agataccaca ccgaaggaag ctgtagggga tctgggactt
     3961 agtcaggcta gctaagggca ctgagtgatt acagggcaag gccacagagc ggcaggaagt
     4021 tgtaagtgca ggggccaggc acagtctgag tggagagcca tgatggcact catccctggc
     4081 tggctcctgg gcccaggccc ttgctcagaa tacagtgccc aggcccgcct gggcattgcc
     4141 ttaattcctg tctgaggctg ccttccgtca tcctcctcaa gctgactgct atcagcagga
     4201 gaagggaatg cagaaccacc cccaccccaa ctccagtgtc tccagaactg agcagggacc
     4261 ctccccatga cggagacaga caacccaatg gcagggcctg ggggagttct aacctcccgt
     4321 gcccaagcct gacttccctt ccctctccag atactgagga aagtgggttg gaggtgggcc
     4381 atgagggtgg gggacagggg gagggagagc catttcctaa gaagagccca ggttgtctca
     4441 gcccagggag actggtttca ggagctgttc cttcagaaag gacgatggaa atggaagtca
     4501 cagcagggct ggggaactgg ggactggtta ggttggaccc atgggtgcag caccctccaa
     4561 actggtgtca gagcctgcag atgagtcccg ggaggagcgg ccctgcagga agcggatgat
     4621 cttctcaatg gtggcctcct ggtattcgtg ggaccacctg tgggcacagg agccaatgtg
     4681 gttcagacag ctgggcagag ggagctgcta gtcagctgtt tgcccacact ctgcctgtca
     4741 tggtgatttg taccctaccc ccctggtccc agggccctgg ggctcacttg ataccgttga
     4801 aagtaagcac agcctgcatg tcctcaggca ggacctgggg ctcaggccac tcgaagccat
     4861 caatgatggg cacaatgttc ttgccgcagc ttaaagcagt cacaatctcc tggagaaaga
     4921 aaggaaagga ggaagatacc cctgtaccca tctagggacc cttgtagcca ggcaggtgct
     4981 gggaggccca ctggcccgag gctgggccca gggcaggaca ccagtcctga tgtccacctt
     5041 gatgtctacc ttaacccttg tagtgtaata aaaaataaat atttttcctt tgcccagagt
     5101 tcctggcaca gagctgctaa aacccttgga atctcttgag tgatgagtgt ctttgtatgc
     5161 taaagagatg attccccact gggggcccgg ggggtgctat gggggtagcc tagatagttt
     5221 caggaagagg gctggtcacc agggagacca gggcatgact agaggattgg aactttcagc
     5281 cccacctccc agcctccaga gaggtgctgg agattgagtt caatcaccaa tggccaatga
     5341 tttaatcaat catgcctaca taatggaacc tccataaaaa cccccaaaca aggggttttg
     5401 aagagcctcc aggttgataa acaggtgtag gtgctgggaa ggtggtagaa ggcatggcat
     5461 ccacacctcc accctccata cgtagagatc ctatgtatct cttccatttg gctattcttg
     5521 agctgtgtcc tttataactg tgaaattaaa taattcagct gggcatggtg ggtcacgcct
     5581 gtaatcccaa cactttggga ggctgaggca ggaggatcac ttgagcccag gattttgaga
     5641 ttaataatat tatttattac tattattcaa gctttgttaa atcaaaccta aagctcttgg
     5701 aactttaagt tattctgagc cttgacagga attggtctct gcagcctgag tcatggggca
     5761 tgcagctgca acttccacct attttttttt tttctgtaat tacttaggaa gaccaaatgg
     5821 caccagagat aagactccct tagatcccca cttagatcac caccctttct cagggggtaa
     5881 taaagtcatc ttccttggaa tgtagcaatc tataaccaat caaagcactg taacatacgc
     5941 actggtcttg tatggaaaat gttgtaatcc tgctaaaatt cctctctctt tgcctgtgga
     6001 agtgaaacct taacttctcc agtttggaat gctcacccca tgcctttgga gtcaatgctt
     6061 actgggtggc tattctcaaa ctttgcactc aaagaaactc tatacttagt cttattttct
     6121 gaatctcatt atttaaggtt gacataataa acaactaata gtaagtaaag tg
//
