LOCUS       NM_001001479            2585 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens solute carrier family 35 member E4 (SLC35E4),
            transcript variant 1, mRNA.
ACCESSION   NM_001001479
VERSION     NM_001001479.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2585)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2585)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005006.2 and BC040191.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001001479.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC040191.1, SRR1803614.181515.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000343605.5/ ENSP00000339626.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                AC005006.2         85063-85096
            35-2016             BC040191.1         9-1990
            2017-2017           AC005006.2         96607-96607
            2018-2585           BC040191.1         1991-2558
FEATURES             Location/Qualifiers
     source          1..2585
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.2"
     gene            1..2585
                     /gene="SLC35E4"
                     /note="solute carrier family 35 member E4"
                     /db_xref="GeneID:339665"
                     /db_xref="HGNC:HGNC:17058"
     exon            1..1289
                     /gene="SLC35E4"
                     /inference="alignment:Splign:2.1.0"
     CDS             671..1723
                     /gene="SLC35E4"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="solute carrier family 35 member E4 isoform 1"
                     /protein_id="NP_001001479.1"
                     /db_xref="CCDS:CCDS13882.1"
                     /db_xref="GeneID:339665"
                     /db_xref="HGNC:HGNC:17058"
                     /translation="MCRCPPEHHDGRMTSAEVGAAAGGAQAAGPPEWPPGSPQALRQP
                     GRARVAMAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLVAALACHRGARRPM
                     PGGTRCRVLLLSLTFGTSMACGNVGLRAVPLDLAQLVTTTTPLFTLALSALLLGRRHH
                     PLQLAAMGPLCLGAACSLAGEFRTPPTGCGFLLAATCLRGLKSVQQSALLQEERLDAV
                     TLLYATSLPSFCLLAGAALVLEAGVAPPPTAGDSRLWACILLSCLLSVLYNLASFSLL
                     ALTSALTVHVLGNLTVVGNLILSRLLFGSRLSALSYVGIALTLSGMFLYHNCEFVASW
                     AARRGLWRRDQPSKGL"
     exon            1290..2585
                     /gene="SLC35E4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2565..2570
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC35E4"
                     /note="hexamer: AATACA"
     polyA_site      2585
                     /gene="SLC35E4"
                     /note="major polyA site"
ORIGIN      
        1 gtgagtcgca gcaggagccg cagccggagt cacagccgca gccagagccg cagccaaagc
       61 ctcagagagc aggagttgga gcgcaggccc tgctggatcc gcgcctagct cgccgccagg
      121 caccggccgg aggacgggcc gtggtgtcag ctcactgccc gggcgctgtg ggaggcagcg
      181 agcccgcgac cccccgggcc gggcaccgcc aggcgcggag cccagatcgc ccccctgcca
      241 ggcctggtca cggccagagc acgcaggagt tcccagggtc tggatctgcg cgcaccctaa
      301 tgacctgggg actgaagaga aaaaaggaac gaggatttca tctaaaagca taacgtgggc
      361 actaggcgag gaggaaagtg gagaccacct ggcacggggc agaggtgcct ggagcccacg
      421 cttgagcatc ggagaccctg gcatcctagc agccgcgacc ttggctctgc cctgtctgag
      481 ctggaaacac agcttagctt ctagacatcg ctggcacagg cctggcacaa gtaagcagtg
      541 tcctcacctg tctgaaacgg gacacggggt cggaggaacc aggatctagc ctggccccaa
      601 gcggaactct ctggtggccc agaggtcgtc actggggagc ccgcctcctg ccctagcctc
      661 actggtgcgg atgtgccgct gcccgccgga gcaccatgat ggcaggatga cctcagccga
      721 agtaggagca gcagctggtg gtgctcaggc ggctgggccc cccgagtggc cccctggcag
      781 ccctcaggcc ctccggcagc ctggccgggc ccgagtggcc atggcagcac tggtgtggct
      841 gctggcggga gccagcatgt caagcctcaa caagtggatc ttcacagtgc acggctttgg
      901 gcggcccctg ctgctgtcgg ccctgcacat gctggtggca gccctggcat gccaccgggg
      961 ggcacggcgc cccatgccag gcggcactcg ctgccgagtc ctactgctca gtctcacctt
     1021 tggcacgtcc atggcctgcg gcaacgtggg cctaagggct gtgcccctgg acctggcaca
     1081 actggttact accaccacac ctctgttcac cctggccctg tcggcgctgc tgctgggccg
     1141 ccgccaccac ccacttcagt tggccgccat gggtccgctc tgcctggggg ccgcctgcag
     1201 cctggctgga gagttccgga caccccctac cggctgtggc ttcctgctcg cagccacctg
     1261 cctccgcgga ctcaagtcgg ttcagcaaag tgccctgctg caggaggaga ggctggacgc
     1321 ggtgaccctg ctttacgcca cctcgctgcc cagcttctgc ctgctggcgg gtgcagccct
     1381 ggtgctggag gctggcgttg ccccaccgcc cactgctggc gactctcgcc tctgggcctg
     1441 catcctgctc agctgcctcc tgtctgttct ctataacctg gccagcttct ccctgctggc
     1501 cctcacctct gccctcaccg tccacgtcct gggcaacctc accgtggtgg gcaacctcat
     1561 cctgtcccgg ctgttgtttg gcagccgcct cagtgccctc agctacgtgg gcatcgcact
     1621 cactctttca ggaatgttcc tttaccacaa ctgcgagttc gtggcctcct gggctgcccg
     1681 tcgggggctg tggcggaggg accagcccag caagggtctt tgagacctgg gggatctcag
     1741 gagccacctg ggatggccct ggcctgaatc cagcctccgc tgtggccata gaaggaatgg
     1801 agaacagggc tgggcatggt ggctcacgcc tataatccca gcacttccag agtccgaggt
     1861 gggtggatca cctgaggcca ggagttcgag accagcctgg ctaacatggc aaaacctcat
     1921 ctctactaaa aatagaaaaa ttagctgggc atggtggcgc gtgcctatag tcccagctac
     1981 atgggaggct aaggtgggag gatcacttga gccctggaga tcgaggctgc agtaagccaa
     2041 gatcgcatgc tactgcactc cagcctggga gacagagcga gacgctgtct caattaaaaa
     2101 aaaaaaaaag tggagaactg gcagtgacct ctactggggg ccatggcagg gaggggagcc
     2161 ttctggaagg gctgccttgg agattggaat ggggactccc agggagacct gcgttccatc
     2221 cctgcctgcc tcacccctgc cacagactct gcacaccact ggatggtggg tccaagcctg
     2281 gcacagtccc tgtgcttgtc agagtcatta ttatgattaa tatcaattac gatgccaaaa
     2341 attgctgggc aaactttgaa gacctcaact tgttacaatg acgatgatga tgattcttgg
     2401 cggttacaca atccttcctc ctggggggga ggcagctagg aggcccagca ggggggcttc
     2461 tatgctgctg ggctccccta gggagttggg gtagtctgtg ccaactccag gcagctgctg
     2521 tggcctcacc cctgggcccc ccaattttgg gtcatccatc ctcaaataca ctatttttgc
     2581 ttgta
//
