LOCUS       NM_024881               5126 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens solute carrier family 35 member E1 (SLC35E1), mRNA.
ACCESSION   NM_024881
VERSION     NM_024881.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5126)
  AUTHORS   Maeda,F., Kato,A., Takeshima,K., Shibazaki,M., Sato,R., Shibata,T.,
            Miyake,K., Kozuka-Hata,H., Oyama,M., Shimizu,E., Imoto,S.,
            Miyano,S., Adachi,S., Natsume,T., Takeuchi,K., Maruzuru,Y.,
            Koyanagi,N., Jun,A. and Yasushi,K.
  TITLE     Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of
            Herpes Simplex Virus 1
  JOURNAL   J Virol 96 (10), e0030622 (2022)
   PUBMED   35475666
  REMARK    GeneRIF: Role of the Orphan Transporter SLC35E1 in the Nuclear
            Egress of Herpes Simplex Virus 1.
REFERENCE   2  (bases 1 to 5126)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008764.9, BC062562.1 and BU619655.1.
            
            On Nov 22, 2018 this sequence version replaced NM_024881.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062562.1, SRR1803614.126766.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000595753.6/ ENSP00000470652.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AC008764.9         119625-119657       c
            34-2314             BC062562.1         1-2281
            2315-4623           AC008764.9         97582-99890         c
            4624-5126           BU619655.1         17-519              c
FEATURES             Location/Qualifiers
     source          1..5126
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.11"
     gene            1..5126
                     /gene="SLC35E1"
                     /note="solute carrier family 35 member E1"
                     /db_xref="GeneID:79939"
                     /db_xref="HGNC:HGNC:20803"
                     /db_xref="MIM:620337"
     exon            1..472
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1284
                     /gene="SLC35E1"
                     /codon_start=1
                     /product="solute carrier family 35 member E1"
                     /protein_id="NP_079157.3"
                     /db_xref="CCDS:CCDS12346.2"
                     /db_xref="GeneID:79939"
                     /db_xref="HGNC:HGNC:20803"
                     /db_xref="MIM:620337"
                     /translation="MAAAAVGAGHGAGGPGAASSSGGAREGARVAALCLLWYALSAGG
                     NVVNKVILSAFPFPVTVSLCHILALCAGLPPLLRAWRVPPAPPVSGPGPSPHPSSGPL
                     LPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEK
                     QSTKVYLSLIPIISGVLLATVTELSFDMWGLVSALAATLCFSLQNIFSKKVLRDSRIH
                     HLRLLNILGCHAVFFMIPTWVLVDLSAFLVSSDLTYVYQWPWTLLLLAVSGFCNFAQN
                     VIAFSILNLVSPLSYSVANATKRIMVITVSLIMLRNPVTSTNVLGMMTAILGVFLYNK
                     TKYDANQQARKHLLPVTTADLSSKERHRSPLEKPHNGLLFPQHGDYQYGRNNILTDHF
                     QYSRQSYPNSYSLNRYDV"
     exon            473..543
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     exon            544..681
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     exon            682..807
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     exon            808..1053
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..5126
                     /gene="SLC35E1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4083..4088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC35E1"
                     /note="hexamer: AATAAA"
     polyA_site      4107
                     /gene="SLC35E1"
                     /note="major polyA site"
     regulatory      5104..5109
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC35E1"
                     /note="hexamer: AATAAA"
     polyA_site      5126
                     /gene="SLC35E1"
                     /note="major polyA site"
ORIGIN      
        1 gcccggcgtc gggccgtcgg acgggctgga aggggcggcc gctcgggcag gatggcggcg
       61 gccgcggtgg gcgcgggcca cggcgcgggg ggcccgggcg cagcgagcag cagtggtggg
      121 gcgcgcgagg gcgcgcgggt ggcggcgctg tgcctgctgt ggtacgcgct gagcgcgggc
      181 ggcaacgtgg tcaacaaggt gatcctgagc gccttcccgt tcccggtgac cgtgtcgctg
      241 tgccacatcc tggctctgtg cgctgggctc ccgccgctgc tgcgcgcctg gcgcgtgccc
      301 cccgcgccgc ccgtctcggg ccccggaccc agtccgcatc cgtcgtccgg cccgctgctg
      361 ccgccgcgct tctacccgcg ctacgtgcta ccgctcgcct tcggcaagta cttcgcgtcc
      421 gtgtcagcgc acgtcagcat ctggaaggtg cccgtgtcct atgcacacac cgtcaaggcc
      481 accatgccca tctgggtggt cctcctgtcc cggatcatta tgaaggagaa gcagagcacc
      541 aaggtatact tgtcactcat ccccatcatc agcggtgtcc tgctggccac cgtcaccgag
      601 ttgtcttttg acatgtgggg actcgtcagc gccctcgccg ccacgctgtg cttctcgctt
      661 cagaacattt tctccaaaaa ggtcttgcga gattcacgga tccaccatct ccggctgctc
      721 aacatcctgg gctgccacgc cgtcttcttt atgatcccca cctgggttct ggtggacctc
      781 tcggctttcc tggtcagcag cgacttgacc tacgtctacc agtggccctg gacgctcctg
      841 ctcctggctg tcagcggctt ctgtaacttt gcccagaatg ttatcgcctt cagcatcctc
      901 aacctcgtta gccccctgag ctactcggtc gccaatgcca ccaaaagaat catggtcatc
      961 acggtgtccc tgatcatgct gcgcaaccca gtcaccagca ccaacgtcct gggcatgatg
     1021 accgccatcc tgggggtctt cctctataac aagaccaagt acgatgcaaa ccagcaagcc
     1081 aggaagcacc tcctccccgt caccacagca gacctgagca gcaaggagcg tcaccggagc
     1141 ccactggaga agccccacaa cggcctcctc ttcccccagc acggggacta tcagtacggc
     1201 cgcaacaaca tcttaacaga ccacttccaa tacagccggc agagctaccc aaactcgtac
     1261 agtttgaacc gctatgatgt gtagagtcca aaggacagga ccagactgtt ggtgactcct
     1321 tccccggccc ccacagcagt atcagaaact tctgacaatc agtgaatgta caacccagcc
     1381 gaggggacgg tgcataactc tccatcagaa gccctggggt tcctggcccc ccgtgagccg
     1441 caggaggatg cgttgcctgc agtgcagacg gccgtgagct ctgggcaaac ctaaacagag
     1501 accagtgtct catgctcttt cttcctggag tctgtcatct gagggccgtg tccctgcgga
     1561 gatcttggcc acgttgtacc tttccatgtg gaattattcc ccaagcagtg tagctcagag
     1621 cacttgtgtc tgcattccag ataacattca ggacctgtgt gaaaagctgg ggtcactgtg
     1681 gctgtagacc atgaactggc agtgggggtg tccagggcgg tgcttgagaa cgtcagactg
     1741 gctagtttaa ttccctggcg cagatacgca taggaccaac agggtcacca agcagacagg
     1801 gagcccgcga gaatcattca aaacatcccc agccacagag atggatccag tttcctggtc
     1861 atccccttag cagttcacaa gttcctggca aatgttccaa agcaaaaagc gattgcaatt
     1921 agcatccagt tcctgcagcc tggtgctctg ccctgcacgt cagggttggc atccacccag
     1981 atccagatgg aagggaaact tctctcttct cctttgcctc ctcttccctc accagagcag
     2041 ggcgcttctc ttggggtggt gagaaggatc ttcgagaaat cgtgttcagt atttcaagct
     2101 ctatttctgt ggcacatgtc ttttgagagg catcttcacc tcttctgtga tgacttggta
     2161 tgttgtttgg tagagagatc ttgattttcg gaggatcttg catttttcta gggaatattt
     2221 tgtagttgtg tgtgtgtgtt tttgccttgg tccccattat gggatgcatt aggactggcc
     2281 tatgcatcga aaatcttttt gtttgtaaac gtttaaaaac aaagttcccc ggccaggcac
     2341 agtggctcac acctgtaatc ccagcacttt gggaggccaa gatgggcgga tcacgaggtc
     2401 aggagttcga gaccagcctg gccaacatag tgaaacccca tctctactaa aaatacagaa
     2461 attagccggg catggtgtcg cgtgcctgta gtcccagctc ctcaggctgc tgaggcaggc
     2521 gaattgcttg aacctgggag gcagaagttg tggtgagccg agattgtgca ctccagcctg
     2581 ggtaacagag cgagactcca tctcaaaaaa aaaaacaaaa caaaaccaag ttcccactgg
     2641 tgatgcctgt ctgacacgtt ttggtattta gtaggaaatg aagtgtttcg aagcttcgag
     2701 agaagcttca aaattgtcac aattgctgaa aacagaatga atcgtgaaca ttatctcaat
     2761 attttgtata atagacaaga ccacagtgtt ttggttccct gacctgtttt tgtgtttatg
     2821 ttaggatctg aatcatgttc tgggtaaggg gacgaggagc gaacactgca ctaagatttg
     2881 gtttgccaaa tcagattctt tggtcaagag tcagtttggg gccaggcgtg gtggctcatg
     2941 cctgtaatct cagcactttg ggaggctgag gtgggtggat cactggagtt tgagaccacc
     3001 ctggccaaca tggtgaaacc ccatctctac taaaacaaaa attagccagg catggtggca
     3061 cctgcctgta atcccagcta cttgggaggc tgaggcagga gaatcacttg agcccaggag
     3121 gtggaggttt cagcgagctg agatcacacc actgcactcc agccttggtg acagagtgag
     3181 actctgtctc aaaaaaaaaa aaaaaaaaaa ggaatcagtt tgggtcttgg cagaaatcaa
     3241 cataaggaat atgacaagac cccagtaggt aaccctgagt gctcaggtcc gagctgtggt
     3301 ctcttttacg gcttcatgaa aggaccgtgc cctcacggag gggaccacgg cttggcttgt
     3361 ggggtcttag gtgatggctg ccttctttct tcatcaccac acccagcttc ttgctggcac
     3421 ttaggggaag agagcagcaa atgagagatt taccttttat ctcccagcga gcgagatgtt
     3481 tccctgttca gagaggaagt aacatcactt atgcttgact ggtgtttctt ttgttgttgt
     3541 ttgtttttct ttcaattgga attctgtatt taagatgtta tgtcagctga cacatgggac
     3601 actcctgaag aggtgactgg ccccccaccc tgtttggcgg tgagtttccg caccaccggc
     3661 ctcagaagtg tccctcttgc ttcgtctctt gttcgcttgc tttgtaaata ctttggtccc
     3721 aagctgagac aattgctgtg taaaacgtga agagtcaatc ccaaagggtg ttatttgtca
     3781 gaagaacttg ccgtgtgcct tcaccgaagg cagtcaagtc tgcagttgga tttttctcac
     3841 tggtgaatga caagaaacag ggataatttt gcactgcgga gatattacgg gagttgtcta
     3901 tatgattata tatagtacct gattctttga acatattatt gaactccaaa atgaattcga
     3961 cctccattca ggcttcctga aatctctgaa gttgctgaaa tttgtatatt attttccttt
     4021 tccaatgcaa gatctgctgg tgacgggaaa tgactgtctg gttttattat ggtttataaa
     4081 ttaataaatg ggctatttaa ttctgtatat aaatttacag caagtacgta cactggaatg
     4141 aatgaggcaa tcacgttaca ccaaatcagc agatcaaaag acaaacacat atttctgaga
     4201 cttgaaggtc cacatccccc cgccccctgc caagatggag tcttgctttg ttgctcaggc
     4261 tggagtgcag tggcgcagtc tcagctcact acaacctcca tcccccgggt tcaggtgatt
     4321 ctcgtgcctc agcctcccga gtagctggga ttacaggcat gcaccaccac ggctggctaa
     4381 ttttttgtgt ttttagtaga gacagggttt caccatgttg gccaggctgg tctcgaactc
     4441 ctggcctcaa atgatccgcc caccttggcc tcccaaagtg ctaggatgac aggcatgagc
     4501 caccgtgccc agcctgattg acaatggcct cttgaaggct gggttttccc agccggacag
     4561 tgcccgcccc acatgctcca ctcccacgct ttcatctgca ggcctgcctt cctctcagcc
     4621 acctcactgc tgagctctgt ggtagagaat ttcctttacc catcagggta tggtctggct
     4681 ggtaatactg actccaaccc agctccttca ttttatagaa ggaggcattt ctgaatcatg
     4741 tttgttcacc atggcgagac tcactgcaga atttttaacc accttatttt aagtcattca
     4801 ttctaggaac agtcaagccc ctaccacaaa ggggccagat ccgttcaagt gaggaagcac
     4861 ttgcagtttc tgaattttgc tgtatatttg tcctatgtca cccaacaggc cctttgctat
     4921 agctgggaca ttaccagacc ccaatacctt agggtctcac agcctgaagg acacagagca
     4981 ttgaattatt aaaagacctg aaaatattat aatgtttttc aattgtcacc tgttttcaag
     5041 acttaaatgc tatagacttt tctgcaggaa tgacgtgtat attcctcact ggcatttacc
     5101 aaaaataaat gatggtttcc agggaa
//
