LOCUS       NM_006345               6164 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens solute carrier family 30 member 9 (SLC30A9), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_006345
VERSION     NM_006345.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6164)
  AUTHORS   Ge,J., Li,H., Liang,X. and Zhou,B.
  TITLE     SLC30A9: an evolutionarily conserved mitochondrial zinc transporter
            essential for mammalian early embryonic development
  JOURNAL   Cell Mol Life Sci 81 (1), 357 (2024)
   PUBMED   39158587
  REMARK    GeneRIF: SLC30A9: an evolutionarily conserved mitochondrial zinc
            transporter essential for mammalian early embryonic development.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6164)
  AUTHORS   Ding,M., Yu,Z., Lu,T., Hu,S., Zhou,X. and Wang,X.
  TITLE     N-acetyltransferase 10 facilitates tumorigenesis of diffuse large
            B-cell lymphoma by regulating AMPK/mTOR signalling through
            N4-acetylcytidine modification of SLC30A9
  JOURNAL   Clin Transl Med 14 (7), e1747 (2024)
   PUBMED   38961519
  REMARK    GeneRIF: N-acetyltransferase 10 facilitates tumorigenesis of
            diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling
            through N4-acetylcytidine modification of SLC30A9.
REFERENCE   3  (bases 1 to 6164)
  AUTHORS   Steel,D.B.D., Danti,F.R., Abunada,M., Kamien,B., Malhotra,S.,
            Topf,M., Kaliakatsos,M., Valentine,J., Nemeth,A.H., Jayawant,S.,
            Reid,K.M., Mankad,K., Sudhakar,S., Ben-Pazi,H., Barwick,K. and
            Kurian,M.A.
  TITLE     Clinical Phenotype in Individuals With Birk-Landau-Perez Syndrome
            Associated With Biallelic SLC30A9 Pathogenic Variants
  JOURNAL   Neurology 100 (21), e2214-e2223 (2023)
   PUBMED   37041080
  REMARK    GeneRIF: Clinical Phenotype in Individuals With Birk-Landau-Perez
            Syndrome Associated With Biallelic SLC30A9 Pathogenic Variants.
REFERENCE   4  (bases 1 to 6164)
  AUTHORS   Kleyner,R., Arif,M., Marchi,E., Horowitz,N., Haworth,A., King,B.,
            Gavin,M., Amble,K., Velinov,M. and Lyon,G.J.
  TITLE     Autosomal recessive SLC30A9 variants in a proband with a
            cerebrorenal syndrome and no parental consanguinity
  JOURNAL   Cold Spring Harb Mol Case Stud 8 (2), a006137 (2022)
   PUBMED   34716203
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6164)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   6  (bases 1 to 6164)
  AUTHORS   Wang,L., McDonnell,S.K., Hebbring,S.J., Cunningham,J.M., St
            Sauver,J., Cerhan,J.R., Isaya,G., Schaid,D.J. and Thibodeau,S.N.
  TITLE     Polymorphisms in mitochondrial genes and prostate cancer risk
  JOURNAL   Cancer Epidemiol Biomarkers Prev 17 (12), 3558-3566 (2008)
   PUBMED   19064571
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 6164)
  AUTHORS   Overbeck,S., Uciechowski,P., Ackland,M.L., Ford,D. and Rink,L.
  TITLE     Intracellular zinc homeostasis in leukocyte subsets is regulated by
            different expression of zinc exporters ZnT-1 to ZnT-9
  JOURNAL   J Leukoc Biol 83 (2), 368-380 (2008)
   PUBMED   17971500
  REMARK    GeneRIF: hZnT-9 was expressed at low levels in leukocytes.
REFERENCE   8  (bases 1 to 6164)
  AUTHORS   Falcon-Perez,J.M. and Dell'Angelica,E.C.
  TITLE     Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect
            of adaptor protein 3-depleted fibroblasts by promoting zinc
            accumulation in lysosomes
  JOURNAL   Exp Cell Res 313 (7), 1473-1483 (2007)
   PUBMED   17349999
REFERENCE   9  (bases 1 to 6164)
  AUTHORS   Sim,D.L., Yeo,W.M. and Chow,V.T.
  TITLE     The novel human HUEL (C4orf1) protein shares homology with the
            DNA-binding domain of the XPA DNA repair protein and displays
            nuclear translocation in a cell cycle-dependent manner
  JOURNAL   Int J Biochem Cell Biol 34 (5), 487-504 (2002)
   PUBMED   11906820
  REMARK    GeneRIF: Results indicate that HUEL, which shares significant
            homology with the DNA-binding domain of XPA, is likely to be a
            conserved, housekeeping gene that is intimately linked with
            cellular replication, DNA synthesis and/or transcriptional
            regulation.
REFERENCE   10 (bases 1 to 6164)
  AUTHORS   Sim,D.L. and Chow,V.T.
  TITLE     The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and
            encodes a nuclear protein containing the nuclear receptor
            interaction motif
  JOURNAL   Genomics 59 (2), 224-233 (1999)
   PUBMED   10409434
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG323207.1, BC007732.2, AY594282.1, BC022981.1, AA427879.1 and
            AC113151.5.
            
            On Nov 22, 2018 this sequence version replaced NM_006345.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.55113.1,
                                           SRR1803616.45714.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000264451.12/ ENSP00000264451.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               BG323207.1         26-170
            146-269             BC007732.2         131-254
            270-1829            AY594282.1         148-1707
            1830-3224           BC022981.1         1245-2639
            3225-3237           AA427879.1         12-24               c
            3238-6164           AC113151.5         68708-71634
FEATURES             Location/Qualifiers
     source          1..6164
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p13"
     gene            1..6164
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="solute carrier family 30 member 9"
                     /db_xref="GeneID:10463"
                     /db_xref="HGNC:HGNC:1329"
                     /db_xref="MIM:604604"
     exon            1..231
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1829
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="expressed in human embryonic lung; GRIP1-dependent
                     nuclear receptor coactivator; zinc transporter 9; znT-9;
                     human embryonic lung protein; solute carrier family 30
                     (zinc transporter), member 9"
                     /codon_start=1
                     /product="proton-coupled zinc antiporter SLC30A9,
                     mitochondrial"
                     /protein_id="NP_006336.3"
                     /db_xref="CCDS:CCDS3465.1"
                     /db_xref="GeneID:10463"
                     /db_xref="HGNC:HGNC:1329"
                     /db_xref="MIM:604604"
                     /translation="MLPGLAAAAAHRCSWSSLCRLRLRCRAAACNPSDRQEWQNLVTF
                     GSFSNMVPCSHPYIGTLSQVKLYSTNVQKEGQGSQTLRVEKVPSFETAEGIGTELKAP
                     LKQEPLQVRVKAVLKKREYGSKYTQNNFITGVRAINEFCLKSSDLEQLRKIRRRSPHE
                     DTESFTVYLRSDVEAKSLEVWGSPEALAREKKLRKEAEIEYRERLFRNQKILREYRDF
                     LGNTKPRSRTASVFFKGPGKVVMVAICINGLNCFFKFLAWIYTGSASMFSEAIHSLSD
                     TCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLISGVGIFMMGAGLSWYHGVMGLL
                     HPQPIESLLWAYCILAGSLVSEGATLLVAVNELRRNARAKGMSFYKYVMESRDPSTNV
                     ILLEDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGVGTLLGMVSAFLIYTNTEALL
                     GRSIQPEQVQRLTELLENDPSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEK
                     QDFDQMLQEIQEVKTPEELETFMLKHGENIIDTLGAEVDRLEKELKKRNPEVRHVDLE
                     IL"
     exon            232..396
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            397..456
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            457..556
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            557..649
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            650..732
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            733..791
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            792..859
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            860..962
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1018
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1154
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1194
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1266
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1374
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1540
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1670
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1784
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..6164
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3204..3209
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="hexamer: AATAAA"
     polyA_site      3205
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
     polyA_site      3224
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="major polyA site"
     regulatory      3873..3878
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="hexamer: CATAAA"
     polyA_site      3891
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
     regulatory      6133..6138
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
                     /note="hexamer: AATAAA"
     polyA_site      6164
                     /gene="SLC30A9"
                     /gene_synonym="BILAPES; C4orf1; GAC63; HUEL; ZNT9"
ORIGIN      
        1 aggcagcttg tggcggcgaa gccatcggtg ttcgctgatg tccagtctat ggagtcagtt
       61 ggtaccggtg gcggcgcgga ggcagaaggc ggtgtccgag taggggcctc tgccccacca
      121 ggatgttacc cggcttggcc gccgccgcgg cccacagatg tagctggtcc tccctgtgcc
      181 ggctccgtct gcgatgcagg gcggcggcct gtaatcccag cgaccgccag gagtggcaga
      241 atttagtgac atttggaagc ttttcaaaca tggttccctg tagtcatcca tatattggta
      301 ccctgagtca agtaaagttg tactccacaa atgttcagaa agaaggacag ggatcacaaa
      361 cactcagagt ggaaaaagta ccatcatttg aaacagcaga aggtataggc acagaactca
      421 aagctccact taagcaagaa cctctccaag taagagttaa agcagtcctt aagaaaaggg
      481 agtatggctc aaagtacact cagaataatt tcatcactgg agtcagagcg ataaatgagt
      541 tctgcctcaa atccagtgat ctagaacaac ttcgaaaaat cagacgacga agtccccatg
      601 aagatactga gtcttttact gtatacttga gatcagatgt ggaagcaaaa tctttggaag
      661 tttggggaag ccctgaagct cttgccagag agaaaaaatt gcgtaaggaa gcagaaatag
      721 aatacagaga aaggctattt agaaaccaaa aaatattaag agaatacaga gatttcttgg
      781 gaaataccaa gccacgctcc agaacagcat cagtgttttt taagggacca ggaaaagtgg
      841 tgatggttgc aatttgcatc aatggattaa actgcttctt taaatttctt gcctggattt
      901 ataccggttc agcaagtatg ttctcagaag ctatacactc attatctgat acttgtaatc
      961 agggtttact agcattgggc atcagtaagt ctgttcaaac accagatcct tctcatccgt
     1021 acggattttc aaatatgcgc tatatttctt cgctaattag tggtgttggt attttcatga
     1081 tgggtgcagg actatcttgg taccatggag tcatgggatt gcttcatcct caaccaatag
     1141 aatcccttct atgggcatat tgtattttag caggatcatt agtatctgaa ggagcaacac
     1201 ttcttgttgc tgtaaatgaa cttcgtagga atgctcgggc taaaggaatg tcattttaca
     1261 agtatgtaat ggaaagtcgt gatcctagta caaatgtgat attattggag gatactgctg
     1321 cagtcttggg agttataata gcagccactt gcatgggcct tacttctata acaggcaatc
     1381 cactgtatga cagcctaggt tctttgggtg tgggcacctt attaggcatg gtctcagcat
     1441 tcctcatcta cactaacaca gaagcactct tagggcggtc catccagcca gaacaagtac
     1501 aacggctcac tgaactcctg gagaatgacc catcagtaag ggcaattcat gatgttaaag
     1561 ccacagatct gggattaggt aaagtaagat ttaaggcaga agtagatttt gatgggcgag
     1621 ttgttacaag atcatatttg gaaaaacaag attttgacca aatgttacaa gaaattcaag
     1681 aagtgaaaac tcctgaagaa ctagagacct ttatgcttaa acatggagaa aatattattg
     1741 atactttagg agctgaagta gatagacttg agaaggaact gaaaaaacga aatcctgaag
     1801 ttcgacatgt agatttggag atactgtgag tttgatggaa tgaatcacct gggtggggac
     1861 cttggaaaca agtttgtccg tccactctac aaagtttcct cctctcctac actgaaagac
     1921 tcagtgccat gcagaagcct tttttttaag atgaaggaaa tattttatgt aaagagcaac
     1981 tcagcaggac acagaactaa aactactact tacatctaac agacacacta caagttgaat
     2041 caatttgaaa atcatgtttt tatgcttcca tagggaacat tttggttatt taaattgttc
     2101 ataatgtccc atatttcacc tgttcagtgt atactgtact ttgcaatcat ctttcctttt
     2161 ttcacattgg taaaaataag tggcatccat aggatcatga tttttaattt gttgcctctg
     2221 aagatttcac tccatcaaga tctgccaatc ttcaatattc tggctaaatc ttggtatgtg
     2281 gtttttaaac agtcactccg tttcaaagtc tgtctttcct tatagaatgt ggaaattatt
     2341 tctccatacc ttgtgatttt gacctgagtg ctaagagaat cactctcctt acctagttat
     2401 ctacaaatgt tcattccaga aatgtttagt tactgaattg aatgaagaca tctcagtaca
     2461 ctcttttagg tcatagtagt tgccattttg taaaatttct tttttcttct ttgctttttt
     2521 ccccttattt ggtttaattt ttctaatgtt aggagatata gtcctagata tttccatggg
     2581 ccagtgtgat gacttttttt taaatgaggt tcagtaccat aatgtttatt tactggaaga
     2641 taatgcattt ataagcattt taaaattctg taaagtgggt tagaaatatt tataatttta
     2701 caggcaggac agcatttgac ttttatttaa aaggcggcac tacttatgta aatctgagct
     2761 gtgggatatt tcttgcttta agagagagac agaatctctc actgaaactc atggtcatga
     2821 ttttgtataa tatagttcat actgtgtctg tgagtttctt cagttacaaa tgggcattta
     2881 gtatagttat attgactata acatgtaagt aaatagcttt ctactgaccc taagttatca
     2941 aggtggaaaa aaaacatgca attcagtaat tgaaaatgtg gtgaaaagct gcagctgtca
     3001 tcatcaaaac aactcataac atactttaaa atgttcaggt agcagtgagc attgttcata
     3061 tgagaatggc ggctgggtga tctctttgct gaattaatga gttcttaaca tgtggaccca
     3121 actgcctgtg tgagatctgt gtcttaaaac ttactggaat ggaaatctat gaattattgc
     3181 aaattgtaat gctggaaaca aaaaataaat ccttggttaa agggtttgta atggtgattt
     3241 ttgacccaga aatctcattt actggaaaat tgtgagactt tacgttggtg tatttttctt
     3301 tttttttttt ttactattac agagtatttt gcatgctgta cattttaagt gaaataacat
     3361 tccagtttta tttttaagat agaaaattgt tatatatata tataatttga tactctattc
     3421 ttacagtttc aaattcctta tcccttcttt acaaaaaaaa cttttttttt acctgttatg
     3481 atttattcta tacttttttc ttcttccttc ccctttccca cttgccattt attacttcat
     3541 gtcattgcca tatgagaaag taccaaatta tatccagttt cctcctagtg atattactct
     3601 gaaaaatttc acaaagccag acaagaataa ttactcattt tttttcccaa gacgaccctc
     3661 aaagttaatg tgcagcaggt attccaaatg gtaatttttt ttttttagga ttccctaata
     3721 aaaaaaaaaa aaattctgat atttcttttt aaatctgatt ttggttgagg tcataccatt
     3781 cttaaataat aattgaaggt ttatgttgcc atcttttcta attctgtttt gcactgataa
     3841 acttacataa agtttgttta tgtaaaataa gacataaagg agtacaacat atcaaggaat
     3901 ttgagtattt atgtggaatc aggaaatttt tctagagtca ctgaattttc aaatcagaga
     3961 atttgggctg gatatggtgg cttatgcctg taatcccagc actttgggag gccgaggcag
     4021 gaggattgct tgagctcagg aggtcaagac cagcctgggc aacacagcga gacctcatct
     4081 ctactaaaaa aagttagccg ggtgtggtgg tgctcacctg tgttagtcca ttctcacact
     4141 gctataaaga aatacctgag actgagtaat caaaaaaaga gctttaattg gctcatggtt
     4201 ctgcagactg aacaggaaac atagcagctt ctgcttctgg ggaggcctcg ggaaacttca
     4261 ttcatggcag aatacgaagg ggaagcagtc atagccagag gaagagcaag aggcggggat
     4321 tgggggtagg tgccacactc ttgtaaacaa ccagatctca tgagaactca ctatacagta
     4381 ccaagagggg aaggtgctaa agtattcatg agaactccac ccccgtgatc cagtcatctc
     4441 ccaccaggcc ctacctccaa catgggatta caattcgaca tgagatttgg tggggacaaa
     4501 gatccaaagc atatcagcat ctgtagtcac agctacttgg gaggccgagg tgggaggatc
     4561 acttgagccc cagaggtcga ggctgcaatg agctatgatc atgccactcc agcctgaatg
     4621 acagagtgag atcctgtctc aaaaagagaa tttgggtctc tttctccaaa aataaggcta
     4681 tatttagttt ttcaggtttc ttgttatttt accaaattaa tgtttcttac tttgtatcta
     4741 ctttggcata tagcatttga gtattaaagc atataaatca tttttaagga aaatattctc
     4801 tgcaggagaa taattacaaa aataatactg gacagaggag gggcagtcaa gggtccatga
     4861 ttgattcctt cttgcccaaa actaaaatct aggatttatc aaaggtgagg tatacagtgg
     4921 tccctgactt ataatggttg cacttaagaa tttttatgat gggtttattg gcacataacc
     4981 caataataag taaaaagcat ctgtacctac ttttagcttt ggctgagaat ggatctctaa
     5041 ttcactgtaa gtagcagtcc ccaaactata taaggtggca cagttttcat catggcagtg
     5101 ggaggatgag gggtggagtg tttttgtttt ttttgttttt ttttgagaca gagtttcgtt
     5161 cttgttgccc aggctggagt gcactggcac aattgcagct caccgcaacc ttcacctccc
     5221 gattcaagtg attctcctgc ctcctgagta gctgggatta caggcatgcg ccaccacacc
     5281 cggctaattt tgtatttctg gtttagacaa ggtttctcca tgttggtcag gctggtcttg
     5341 aactgccgac ctcaggtgat ccgccctcct cggcttccca aagtgctggg attacaggtg
     5401 tgagccactg ctccggtgat ctgtttttaa gtggagtatc ctgggggcct atagtatcca
     5461 actccaaaga ggtaagttcc tgaacataca ctaaagaacc tgtgagataa gatcagacgg
     5521 aaaaattttc aaattttttc aaaagcaaag gtaatccctg catacatcct cctacacaca
     5581 cacacatagt gcaaagtgaa taacaaaatg tcataaggct tgagtttttg gtatatggct
     5641 ttcagtgtta ccttatctca taatttaggt aatgattttt gctaaaatga taaccatcta
     5701 aagagtgcct aagttttaag tctcgtaact ttttgaggaa gaatgctggg aactacagaa
     5761 aactgcatag gcatttagaa tttgtattat cttcttagac tgcatttgtc aagctttggc
     5821 agcatttctt ttaaatgtga tgaaccccaa tttgccaaac tgtcagaagt cagtgaagca
     5881 aagaatcgaa ggtaaaatgt tgattcaaag attgtctccc ctaaatcctt catttctttc
     5941 tctgaaatgg aactttggaa gccatttata tagattagtc tgacagcctt tatatttgca
     6001 tgtaagttta cttgcatcct tagacttggc tttatgcaaa aagaaaattt ttattcgtta
     6061 tattgtattt catctgtctg atttccctgg cacattaaga tggtcctggt ccctcaggat
     6121 actttttccc ttaataaatg tcatatgtaa ataaaggcaa ctca
//
