LOCUS       NM_001170798            2923 bp    mRNA    linear   PRI 31-MAY-2024
DEFINITION  Homo sapiens solute carrier family 15 member 5 (SLC15A5), mRNA.
ACCESSION   NM_001170798
VERSION     NM_001170798.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2923)
  AUTHORS   Sundell,G.N., Arnold,R., Ali,M., Naksukpaiboon,P., Orts,J.,
            Guntert,P., Chi,C.N. and Ivarsson,Y.
  TITLE     Proteome-wide analysis of phospho-regulated PDZ domain interactions
  JOURNAL   Mol Syst Biol 14 (8), e8129 (2018)
   PUBMED   30126976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2923)
  AUTHORS   Ivarsson,Y., Arnold,R., McLaughlin,M., Nim,S., Joshi,R., Ray,D.,
            Liu,B., Teyra,J., Pawson,T., Moffat,J., Li,S.S., Sidhu,S.S. and
            Kim,P.M.
  TITLE     Large-scale interaction profiling of PDZ domains through proteomic
            peptide-phage display using human and viral phage peptidomes
  JOURNAL   Proc Natl Acad Sci U S A 111 (7), 2542-2547 (2014)
   PUBMED   24550280
REFERENCE   3  (bases 1 to 2923)
  AUTHORS   Sreedharan,S., Stephansson,O., Schioth,H.B. and Fredriksson,R.
  TITLE     Long evolutionary conservation and considerable tissue specificity
            of several atypical solute carrier transporters
  JOURNAL   Gene 478 (1-2), 11-18 (2011)
   PUBMED   21044875
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073574.11.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments, including macaque AB169295.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968968, SAMEA2142680
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000344941.3/ ENSP00000340402.3
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-361               AC073574.11        165168-165528       c
            362-584             AC073574.11        160404-160626       c
            585-754             AC073574.11        145544-145713       c
            755-975             AC073574.11        132423-132643       c
            976-1162            AC073574.11        127524-127710       c
            1163-1351           AC073574.11        112257-112445       c
            1352-1483           AC073574.11        104736-104867       c
            1484-1592           AC073574.11        82188-82296         c
            1593-2923           AC073574.11        76328-77658         c
FEATURES             Location/Qualifiers
     source          1..2923
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p12.3"
     gene            1..2923
                     /gene="SLC15A5"
                     /note="solute carrier family 15 member 5"
                     /db_xref="GeneID:729025"
                     /db_xref="HGNC:HGNC:33455"
                     /db_xref="MIM:620324"
     CDS             1..1740
                     /gene="SLC15A5"
                     /note="Peptide/histidine transporter ENSP00000340402"
                     /codon_start=1
                     /product="solute carrier family 15 member 5"
                     /protein_id="NP_001164269.1"
                     /db_xref="GeneID:729025"
                     /db_xref="HGNC:HGNC:33455"
                     /db_xref="MIM:620324"
                     /translation="MSVTGFTITDEKVHLYHSIEKEKTVRHIGDLCSSHSVKKIQVGI
                     CLLLVELCERFTFFEVVCNMIPFCTIKLGYHNCQAAILNLCFIGTSILTPVFVRWLTD
                     VYLGRNKLVYICLFLHFLGTALLSVVAFPLEDFYLGTYHAVNNIPKTEQHRLFYVALL
                     TICLGIGGVRAIVCPLGAFGLQEYGSQKTMSFFNWFYWLMNLNATIVFLGISYIQHSQ
                     AWALVLLIPFMSMLMAVITLHMIYYNLIYQSEKRCSLLTGVGVLVSALKTCHPQYCHL
                     GRDVTSQLDHAKEKNGGCYSELHVEDTTFFLTLLPLFIFQLLYRMCIMQIPSGYYLQT
                     MNSNLNLDGFLLPIAVMNAISSLPLLILAPFLEYFSTCLFPSKRVGSFLSTCIIAGNL
                     FAALSVMIAGFFEIHRKHFPAVEQPLSGKVLTVSSMPCFYLILQYVLLGVAETLVNPA
                     LSVISYRFVPSNVRGTSMNFLTLFNGFGCFTGALLVKLVYLISDGNWFPNTLNKGNLE
                     SFFFFLASLTLLNVLGFCSVSQRYCNLNHFNAQNIRGSNLEETLLLHEKSLKFYGSIQ
                     EFSSSIDLWETAL"
     exon            1..361
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            362..584
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            585..754
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            755..975
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1162
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1351
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1483
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1592
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..2923
                     /gene="SLC15A5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctgtta caggctttac cataactgat gagaaagtac acttatatca cagcattgag
       61 aaggagaaaa ctgtaagaca tattggcgat ttgtgttcct cacactctgt gaaaaaaatt
      121 caggttggaa tctgcttgct tctggtggag ctgtgtgaga ggttcacgtt ctttgaagtc
      181 gtctgcaaca tgatcccctt ttgcactatc aagcttggct atcacaattg ccaagcagcc
      241 atcttaaact tgtgttttat tggaacttca atacttaccc ctgtgtttgt cagatggctc
      301 actgatgtct atttaggaag aaacaaactg gtgtacattt gcttgtttct acattttcta
      361 ggcactgctt tgttatctgt ggtggctttt cccttggaag atttctatct gggcacttac
      421 catgcagtta acaacatacc aaaaacagag cagcacaggc tgttttatgt agcactgctg
      481 accatttgcc ttggcattgg aggcgtaaga gccatcgtct gtccactggg tgcttttggc
      541 cttcaggagt atggatcaca aaaaacgatg tcttttttta actggtttta ttggctcatg
      601 aacctaaatg caactattgt gtttctggga atatcttaca tccagcactc acaggcctgg
      661 gcccttgttt tacttattcc ttttatgtct atgcttatgg ctgtgataac tcttcatatg
      721 atatactaca acctaattta tcagtcagaa aaacgttgtt ctctcctgac aggcgttggg
      781 gtgttggtta gtgcactgaa aacatgccac ccgcaatact gccatcttgg cagagacgtg
      841 acaagccagt tagaccatgc caaagaaaaa aatggtggct gctacagtga gctccatgta
      901 gaagacacaa catttttcct cacccttctc cctctcttca tttttcagct cctatacaga
      961 atgtgcatta tgcagattcc ttcaggatat tatctgcaaa ctatgaattc caacctgaat
     1021 ttggatggat ttcttctgcc gattgcagta atgaatgcca tcagcagcct accattacta
     1081 attctggctc cttttctgga gtatttcagc acctgcctgt ttccctctaa gagagttgga
     1141 tcatttctgt caacatgcat cattgctgga aatctttttg ctgcattgtc tgtgatgata
     1201 gctggcttct ttgaaataca ccgaaaacat ttccctgcag tggagcagcc cctttcagga
     1261 aaagttctca ctgtttcctc catgccctgt ttctacctga ttcttcagta tgttttactt
     1321 ggagtggcgg aaacactggt aaacccagcc ctctctgtaa tatcatacag atttgttcca
     1381 agcaatgtca gaggaacctc catgaatttt ctgacactgt tcaatggatt tggctgtttc
     1441 acaggggcac tgctggtgaa gttggtatat ctcatctcag atggcaattg gtttccaaac
     1501 acattaaaca aaggcaattt agaaagcttc ttcttcttcc tggcatcatt aacattgttg
     1561 aacgtcctgg gattctgcag tgtttcacaa agatattgta atctaaatca ttttaatgcc
     1621 cagaacatcc gtggaagtaa tcttgaagaa acacttctcc tccacgaaaa atctctgaaa
     1681 ttttatggca gtatacagga attttcttca agtattgatc tttgggagac agccctatga
     1741 aactgtgttt gagtctacct gtcttatgag aacagtattc attgttttct tcttcagttg
     1801 agcattttat gtgttttagt gtaaaagcca atatatacag aggtgatttt acaaatatca
     1861 tctgtatact ttatttacaa agactaatta tgaattttct agtaaactgt catgcttttg
     1921 cattaacatg ttatagcatt agaattaata aaataatttc aaagtctcag tgattactct
     1981 atgacaaaaa aaatgacagt tttctataca ccaataatac cttacagctt tctacaatgg
     2041 ttcagccatt gaaagcgtat gacctttttt ttggagtttt aatgagtcat tagaagcaaa
     2101 atgacagtat tttaatatac tctctttcaa tacacttagt gatcccttat tacacgtgac
     2161 cttattacat tgtgaccata tactgtatat aactgagtaa ataataaaca tatacatgat
     2221 tttctatatt tgctgttaat attatgctat caaaatatga cttcattaag gacattttct
     2281 ctgaatttaa aagcagtatt actaaaatag atgtccttaa caaagagaat gtccgcatac
     2341 taaaaaagtt gaaaaataaa tgtaagttat ggaattattg gaattaaaag aaagaaggaa
     2401 attagggaag ataaaatgag ggggctgaga ggagggtaag tgaccaaacc aaatagagat
     2461 gcttaaagga attatatgaa taacatcttt cggtctccac tgccaattca gatgcattca
     2521 gaaaattatc ttctaagagt ttcttctttc ataagcaaaa atatgtggaa actcattttt
     2581 taaaaaatca aataaaatta aagtctgttt ctcagtagca gtatttgtca acatttggtt
     2641 gaggacaact tgctacaggt gaatctttct ggcccctata cagactgcct taactcaaat
     2701 ctttttttga gattggggtc cagcaattgg tggttttaat aagcacaccc aaatcattct
     2761 catgttccct aaggtttaaa agccattgct ttccaggaca attcatgttg gataggacag
     2821 gtgagtttat cagctgactg caaattattc tgcaattatg cacctccctt gtgtatacat
     2881 aaaatatttt aggtctgtag aataaaagat ttactcaact tga
//
