LOCUS       XM_047445573            3158 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens solute carrier family 11 member 1
            (SLC11A1), transcript variant X3, mRNA.
ACCESSION   XM_047445573
VERSION     XM_047445573.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..3158
                     /gene="SLC11A1"
                     /gene_synonym="LSH; NRAMP; NRAMP1"
                     /note="solute carrier family 11 member 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 20 ESTs, 62 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 34 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6556"
                     /db_xref="HGNC:HGNC:10907"
                     /db_xref="MIM:600266"
     CDS             1..1299
                     /gene="SLC11A1"
                     /gene_synonym="LSH; NRAMP; NRAMP1"
                     /codon_start=1
                     /product="natural resistance-associated macrophage protein
                     1 isoform X2"
                     /protein_id="XP_047301529.1"
                     /db_xref="GeneID:6556"
                     /db_xref="HGNC:HGNC:10907"
                     /db_xref="MIM:600266"
                     /translation="MVRCQLTATSTSQVPRTVLWLTIELAIVGSDMQEVIGTAIAFNL
                     LSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVARPE
                     QGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRADIR
                     EANMYFLIEATIALSVSFIINLFVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPM
                     NNATVAVDIYQGGVILGCLFGPAALYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLR
                     WSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSM
                     PTLMQEFANGLLNKVVTSSIMVLVCAINLYFVVSYLPSLPHPAYFGLAALLAAAYLGL
                     STYLVWTCCLAHGATFLAHSSHHHFLYGLLEEDQKGETSG"
     polyA_site      3158
                     /gene="SLC11A1"
                     /gene_synonym="LSH; NRAMP; NRAMP1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 atggtgcgat gtcagctcac tgcaacctct acctcccagg tgccccgcac cgtcctctgg
       61 ctgaccatcg agctagccat tgtgggctcc gacatgcagg aagtcatcgg cacggccatt
      121 gcattcaatc tgctctcagc tggacgaatc ccactctggg gtggcgtcct catcaccatc
      181 gtggacacct tcttcttcct cttcctcgat aactacgggc tgcggaagct ggaagctttt
      241 tttggactcc ttataaccat tatggccttg acctttggct atgagtatgt ggtggcgcgt
      301 cctgagcagg gagcgcttct tcggggcctg ttcctgccct cgtgcccggg ctgcggccac
      361 cccgagctgc tgcaggcggt gggcattgtt ggcgccatca tcatgcccca caacatctac
      421 ctgcactcgg ccctggtcaa gtctcgagag atagaccggg cccgccgagc agacatcaga
      481 gaagccaaca tgtacttcct gattgaggcc accatcgccc tgtccgtctc ctttatcatc
      541 aacctctttg tcatggctgt ctttgggcag gccttctacc agaaaaccaa ccaggctgcg
      601 ttcaacatct gtgccaacag cagcctccac gactacgcca agatcttccc catgaacaac
      661 gccaccgtgg ccgtggacat ttaccagggg ggcgtgatcc tgggctgcct gttcggcccc
      721 gcggccctct acatctgggc cataggtctc ctggcggctg ggcagagctc caccatgacg
      781 ggcacctacg cgggacagtt cgtgatggag ggcttcctga ggctgcggtg gtcacgcttc
      841 gcccgtgtcc tcctcacccg ctcctgcgcc atcctgccca ccgtgctcgt ggctgtcttc
      901 cgggacctga gggacttgtc gggcctcaat gatctgctca acgtgctgca gagcctgctg
      961 ctcccgttcg ccgtgctgcc catcctcacg ttcaccagca tgcccaccct catgcaggag
     1021 tttgccaatg gcctgctgaa caaggtcgtc acctcttcca tcatggtgct agtctgcgcc
     1081 atcaacctct acttcgtggt cagctatctg cccagcctgc cccaccctgc ctacttcggc
     1141 cttgcagcct tgctggccgc agcctacctg ggcctcagca cctacctggt ctggacctgt
     1201 tgccttgccc acggagccac ctttctggcc cacagctccc accaccactt cctgtatggg
     1261 ctccttgaag aggaccagaa aggggagacc tctggctagg cccacaccag ggcctggctg
     1321 ggagtggcat gtatgacgtg actggcctgc tggatgtgga gggggcgcgt gcaggcagca
     1381 ggatagagtg ggacagttcc tgagaccagc caacctgggg gctttaggga cctgctgttt
     1441 cctagcgcag ccatgtgatt accctctggg tctcagtgtc ctcatctgta aaatggagac
     1501 accaccaccc ttgccatgga ggttaagcac tttaacacag tgtctggcac ttgggacaaa
     1561 aacaaacaaa cgaaaaacat ttcaaaaggt atttattgag cacctgcagg cgtgacctga
     1621 cagcccaagg gtgggtgggg tgagggcttg aggacttggg cgggacacag gctccaaact
     1681 ggagcttgaa atagtgtctg atgaatgtta aattatctat ctatctattt atttatttat
     1741 ttgagacagg gaaagggtct ccctctgttg ccaaggctgg agtgcagtgg cgcaatctta
     1801 actcattgca acctccacct tctgggttca agcgattctc tttattcagc cccgggagtg
     1861 gcgcgcgcca ccacgcccag ctaatttgtg tattttcagc agagacgggg tttgccatgc
     1921 tggccaggct ggtctcgaac tgctggattc aagtgatccg cccatctccg tctcccaaag
     1981 tgctgggaat tacaggcgtg agccaccaaa cccggcctga ttaaagttaa ataaatacta
     2041 gttcccttct cgtccaaagg agcagggaat gggaaccggg aaggcacgaa gtctctaaag
     2101 catccagaag acccctacac cagggtctgg tccgctccta ttcgccgcag cctttctgtt
     2161 ccgcctgcaa cccattttcc agacagtaaa acggcggcgc acttctttct ccgtcaggca
     2221 ccaggtcata aggaacccaa gagtctgtgc ctctgaggcc caaattattt gctgtttcct
     2281 caggggagcc ggcggccgcg actcccacgc cgcgccgtta ccgctccctc tctgctgact
     2341 gctcccccta ggggcagaga cggtcccgac gcccgccatc ccgccccggc ctcacccctc
     2401 cccgccaggc ggaacgacgc ggggaggcgg gcgctcgggg ctcgcgccag gggccccaga
     2461 atccttcggg gagagtgggt gggaggaagc tgtgtgggcg gggagccccc tctgccttag
     2521 ggagcggctg ggcacccatt cgccccattc aggggctgca ctttatagac gttccctagg
     2581 ctgtttctag gctcccccaa gtccctcctc cagcctcgtc gggtccctca gaccccagcc
     2641 caggacctgc ggagggccgc agcgaggaga ggccaacagg cctttcccta gagttgaacc
     2701 tgggccgggt gttgcacctg gaagaacccc cgatttcctg gggacccagc agggcaggcg
     2761 gcctggctcc gcgctcaggt ccggacgctt gtttatgaga agaatttcct ctttcttaaa
     2821 agggcaacga tgcgagtggg tccctcaagg agagaagaga tgggaccggt ctggtgcgac
     2881 ctgggcaagc gctgcagagg gtacctgggc aagagggccg cccgcctcct ctgggtttgg
     2941 cactggagaa gatgggtcca tgccagctga aggaggagat ggatggggga cgtttagcga
     3001 agaaaggcat ctcccagatc ctttagcctc ctggaagtgc ccccgttgta ccccctacac
     3061 acccctcttg gcattgagtg ccagtcctct gccaggctct gtgttacaag ttggggaggg
     3121 cggcaaagtc ccgaattaaa gatgtcagtt ctcaagga
//
