LOCUS       NM_001242868            3009 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens SLAIN motif family member 1 (SLAIN1), transcript
            variant 3, mRNA.
ACCESSION   NM_001242868
VERSION     NM_001242868.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3009)
  AUTHORS   Hirst,C.E., Ng,E.S., Azzola,L., Voss,A.K., Thomas,T., Stanley,E.G.
            and Elefanty,A.G.
  TITLE     Transcriptional profiling of mouse and human ES cells identifies
            SLAIN1, a novel stem cell gene
  JOURNAL   Dev Biol 293 (1), 90-103 (2006)
   PUBMED   16546155
  REMARK    GeneRIF: Expressed at the stem cell and epiblast stages of
            embryonic stem cell differentiation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL354831.18, DB500463.1, BQ433296.1, BG391962.1 and BC045177.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001242868.1.
            
            Transcript Variant: This variant (3) uses an alternate 5' exon, and
            thus differs in the 5' UTR and 5' coding region, compared to
            variant 1. The encoded isoform (C) has a distinct and longer
            N-terminus, compared to isoform A.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.52124.1,
                                           SRR1660807.32539.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000418532.6/ ENSP00000400921.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AL354831.18        16667-16833
            168-446             DB500463.1         6-284
            447-458             AL354831.18        17113-17124
            459-617             DB500463.1         300-458
            618-716             BQ433296.1         3-101
            717-788             AL354831.18        17383-17454
            789-1332            BG391962.1         1-544
            1333-1460           AL354831.18        65683-65810
            1461-1510           BG391962.1         674-723
            1511-3009           BC045177.1         608-2106
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q22.3"
     gene            1..3009
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="SLAIN motif family member 1"
                     /db_xref="GeneID:122060"
                     /db_xref="HGNC:HGNC:26387"
                     /db_xref="MIM:610491"
     exon            1..853
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..2000
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="isoform C is encoded by transcript variant 3; SLAIN
                     motif-containing protein 1"
                     /codon_start=1
                     /product="SLAIN motif-containing protein 1 isoform C"
                     /protein_id="NP_001229797.1"
                     /db_xref="CCDS:CCDS73588.1"
                     /db_xref="GeneID:122060"
                     /db_xref="HGNC:HGNC:26387"
                     /db_xref="MIM:610491"
                     /translation="MMAEQVKCASAGVSSGAGSGPVVNAELEVKKLQELVRKLEKQNE
                     QLRSRAASAAAAPHLLLLPPPPPAAPPPAGLQPLGPRSPPAATATAAASGGLGLGLAL
                     GAGGGGGSGSGSGGGSSPAFPGTFCLPSPAPSLLCSLAQPPEAPFVYFKPAAGFFGAG
                     GGGPEPGGAGTPPGAAAAPPSPPPTLLDEVELLDLESVAAWRDEDDYTWLYIGSSKTF
                     TSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQGYTSRGSPLSPQSSIDSELST
                     SELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRHSSSVSLSSGKKGT
                     CSDQEYDQYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRECRRSPSSQYF
                     PSNNYQQQQYYSPQAQTPDQQPNRTNGDKLRRSMPNLARMPSTTAISSNISSPVTVRN
                     SQSFDSSLHGAGNGISRIQSCIPSPGQLQHRVHSVGHFPVSIRQPLKATAYVSPTVQG
                     SSNMPLSNGLQLYSNTGIPTPNKAAASGIMGRSALPRPSLAINGSNLPRSKIAQPVRS
                     FLQPPKPLSSLSTLRDGNWRDGCY"
     exon            854..993
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1143
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1485
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..1641
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1924
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..3009
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2874..2879
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="hexamer: AATAAA"
     polyA_site      2904
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="major polyA site"
     regulatory      2988..2993
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="hexamer: AATAAA"
     polyA_site      3009
                     /gene="SLAIN1"
                     /gene_synonym="C13orf32"
                     /note="major polyA site"
ORIGIN      
        1 ggggactgga gggacgcact gagcatgtgc agatcagctc ggtggtggct gccgcggccg
       61 gaggcgaggg cccggtgctg atgcgaaccg ccggctcggc ctcagcccgc gcgtggtcgg
      121 ccccccaggc cggggcgaca gggaaggagc cgtagcctcc ccgtggcccg aggagccggc
      181 gcggcggcgc gcactccccg gcggccgcgg cgccctcggg gcccacgatg atggcggagc
      241 aggtgaaatg cgcctcggca ggggtcagct ctggagcggg ctccgggccg gtggtgaacg
      301 cggagctgga ggtgaagaag ctgcaggagc tggtgcgcaa gctggagaag cagaacgagc
      361 agctgcggag tcgagcggcc agcgcggccg ccgccccgca cctgctgctg ctgccgccgc
      421 cgccgcccgc cgcgccgccc cccgctggcc tgcagccttt gggtcctcgg agccccccgg
      481 ccgccacggc caccgccgcg gcctcagggg gcctggggct cgggctggcg ctgggcgcgg
      541 ggggcggtgg cggcagcggt agtggcagcg gcggtggctc cagccccgcg ttcccgggca
      601 ccttctgcct gcctagcccc gcgccctccc tgctttgcag cctggcgcag ccacccgagg
      661 cgcccttcgt ctacttcaag ccggcagcag gcttcttcgg cgcgggcggt ggcgggccgg
      721 agccgggggg cgcggggacg ccgccagggg cagctgcagc gccgccctcg ccgcccccca
      781 cgctgctgga cgaggtggaa ttgctggatc tggagagcgt agccgcctgg cgggacgagg
      841 acgactacac ctggttatac attggctctt caaagacgtt cacctcatca gagaaatccc
      901 tgactccttt gcagtggtgt agacatgtcc tagataaccc aactcctgag atggaagcag
      961 cgagacgttc cctgtgcttt agactggagc aaggttacac ttccaggggc tccccactca
     1021 gtccccagtc atctatcgac agtgagctga gtacttcaga attggaggat gattctatct
     1081 ccatgggata taaattacag gacctcactg atgttcagat catggctcgt ctgcaagaag
     1141 aaagtctcag gcaagattat gcttctactt cagcatctgt atcaagacat agttccagtg
     1201 tgtcattgag ttcaggaaaa aaagggacat gtagtgatca agaatatgac caatacagtc
     1261 tggaggatga agaggaattt gatcatttgc caccacctca gcctcgtctt ccaagatgtt
     1321 cccctttcca aagaggaatt ccccattcac agactttctc cagcattcgg gagtgtagga
     1381 ggagccccag ttcccagtat tttccttcaa ataattacca gcagcaacag tattattcac
     1441 ctcaagccca aactccagat cagcaaccaa ataggaccaa tggagataag ctccgaagaa
     1501 gtatgcctaa cctagcccgg atgccaagta caactgccat tagtagcaac attagttctc
     1561 cggtcaccgt gcgaaatagt cagagttttg actcaagctt gcatggagct ggaaatggaa
     1621 tttcaagaat acaatcttgt attccatcac cgggacagct tcaacacagg gtccacagcg
     1681 tggggcattt cccagtgtct atccgacagc ctcttaaagc cacagcctat gtgagtccaa
     1741 ccgttcaagg cagcagtaac atgcctttat caaacggctt acagctgtat tccaacacag
     1801 gaatccccac accgaacaaa gctgcagctt ctgggataat gggtcgcagt gcactcccaa
     1861 gaccttcgtt ggcaataaat gggagtaacc tgcctcgaag caaaattgca caacctgtta
     1921 gaagttttct tcagcctcca aagcctctgt cttcactcag cactctgagg gatggaaatt
     1981 ggagagatgg ttgctactaa tgcagtttta tgtacccttg aaaaatggga aagaagtaaa
     2041 aatgagggtt gtgttaccta gctggctggg tagcagtgga tgttgggata ttctttccct
     2101 tttgtgtttt aatatattta ctgcattgtt tctcaatgga ccagtcacca gagactaatt
     2161 attgcactta aatatttgcc tgagatactg caacattctc aaacccatgg ttgcagtatt
     2221 gtgacactta gatctaggaa gtttttgtag aactgctctg tacctgaata ctttttgaga
     2281 gaattaagat gtatcaataa tgctttgcca tatgagtttt ttaaagtaac ttgttcaatt
     2341 tactcacgtg ttctaaacat ctttccatta catgttctgt attttaatac attgcatatt
     2401 gacaactagg ttctataatg tatgctttga aatttacttt tttatagttt acaggaattt
     2461 tattttttgt gcctatttct ttttacacct atgtgaacca ctatggaaca acttaaattt
     2521 tgtgccataa aaatattttt gtggtaaggt actatttttt tagctctagg gatatatcag
     2581 caaaaacaca tcatgcaatt tgagacacat aattttgtgt tgaatgagca caacataatt
     2641 tgaagcattg caaggagata accagacagc agaattaaat ggtcctgtct ttttcatttt
     2701 taatttattg tcatacatgg gtttcatatt tataacggca tcatgagctc attgcactta
     2761 atacctgcaa tgtttgctac tgtaccacaa ttgattttca atactttatt acgaaggatg
     2821 aaactgtaat gttttattaa caatgcttct ggaaatgaat gcattttaaa gcaaataaat
     2881 ctttttgata gaccttttac aaaatccatt tgcactaatg aatgctttct tatggcatat
     2941 aacttaatat ttgttactgt gtacactgct gttttggaat gttcagaaat aaagactcta
     3001 tttcagcaa
//
