LOCUS       XM_047439917            4260 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens signal regulatory protein alpha (SIRPA),
            transcript variant X6, mRNA.
ACCESSION   XM_047439917
VERSION     XM_047439917.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000020.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4260
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
     gene            1..4260
                     /gene="SIRPA"
                     /gene_synonym="BIT; CD172A; MFR; MYD-1; P84; PTPNS1;
                     SHPS1; SIRP"
                     /note="signal regulatory protein alpha; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 30 ESTs, 726 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 13 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:140885"
                     /db_xref="HGNC:HGNC:9662"
                     /db_xref="MIM:602461"
     CDS             361..1236
                     /gene="SIRPA"
                     /gene_synonym="BIT; CD172A; MFR; MYD-1; P84; PTPNS1;
                     SHPS1; SIRP"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     substrate 1 isoform X4"
                     /protein_id="XP_047295873.1"
                     /db_xref="GeneID:140885"
                     /db_xref="HGNC:HGNC:9662"
                     /db_xref="MIM:602461"
                     /translation="MEPAGPAPGRLGPLLCLLLAASCAWSGVAGEEELQVIQPDKSVL
                     VAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNM
                     DFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRENTGSNERNIYIVVG
                     VVCTLLVALLMAALYLVRIRQKKAQGSTSSTRLHEPEKNAREITQVQSLDTNDITYAD
                     LNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKP
                     EPSFSEYASVQVPRK"
ORIGIN      
        1 tccggcccgc acccaccccc aagaggggcc ttcagctttg gggctcagag gcacgacctc
       61 ctggggaggg ttaaaaggca gacgcccccc cgccccccgc gcccccgcgc cccgactcct
      121 tcgccgcctc cagcctctcg ccagtgggaa gcggggagca gccgcgcggc cggagtccgg
      181 aggcgagggg aggtcggccg caacttcccc ggtccacctt aagaggacga tgtagccagc
      241 tcgcagcgct gaccttagaa aaacaagttt gcgcaaagtg gagcggggac ccggcctctg
      301 ggcagccccg gcggcgcttc cagtgccttc cagccctcgc gggcggcgca gccgcggccc
      361 atggagcccg ccggcccggc ccccggccgc ctcgggccgc tgctctgcct gctgctcgcc
      421 gcgtcctgcg cctggtcagg agtggcgggt gaggaggagc tgcaggtgat tcagcctgac
      481 aagtccgtgt tggttgcagc tggagagaca gccactctgc gctgcactgc gacctctctg
      541 atccctgtgg ggcccatcca gtggttcaga ggagctggac caggccggga attaatctac
      601 aatcaaaaag aaggccactt cccccgggta acaactgttt cagacctcac aaagagaaac
      661 aacatggact tttccatccg catcggtaac atcaccccag cagatgccgg cacctactac
      721 tgtgtgaagt tccggaaagg gagccccgat gacgtggagt ttaagtctgg agcaggcact
      781 gagctgtctg tgcgcgagaa cactggatct aatgaacgga acatctatat tgtggtgggt
      841 gtggtgtgca ccttgctggt ggccctactg atggcggccc tctacctcgt ccgaatcaga
      901 cagaagaaag cccagggctc cacttcttct acaaggttgc atgagcccga gaagaatgcc
      961 agagaaataa cacaggtaca gtccttggac acaaatgata tcacatatgc agacctgaac
     1021 ctgcccaagg ggaagaagcc tgctccccag gctgcggagc ccaacaacca cacggagtat
     1081 gccagcattc agaccagccc gcagcccgcg tcggaggaca ccctcaccta tgctgacctg
     1141 gacatggtcc acctcaaccg gacccccaag cagccggccc ccaagcctga gccgtccttc
     1201 tcagagtacg ccagcgtcca ggtcccgagg aagtgaatgg gaccgtggtt tgctctagca
     1261 cccatctcta cgcgctttct tgtcccacag ggagccgccg tgatgagcac agccaaccca
     1321 gttcccggag ggctggggcg gtgcaggctc tgggacccag gggccagggt ggctcttctc
     1381 tccccacccc tccttggctc tccagcactt cctgggcagc cacggccccc tccccccaca
     1441 ttgccacata cctggaggct gacgttgcca aaccagccag ggaaccaacc tgggaagtgg
     1501 ccagaactgc ctggggtcca agaactcttg tgcctccgtc catcaccatg tgggttttga
     1561 agaccctcga ctgcctcccc gatgctccga agcctgatct tccagggtgg ggaggagaaa
     1621 atcccacctc ccctgacctc caccacctcc accaccacca ccaccaccac caccaccact
     1681 accaccacca cccaactggg gctagagtgg ggaagatttc ccctttagat caaactgccc
     1741 cttccatgga aaagctggaa aaaaactctg gaacccatat ccaggcttgg tgaggttgct
     1801 gccaacagtc ctggcctccc ccatccctag gctaaagagc catgagtcct ggaggaggag
     1861 aggacccctc ccaaaggact ggagacaaaa ccctctgctt ccttgggtcc ctccaagact
     1921 ccctggggcc caactgtgtt gctccacccg gacccatctc tcccttctag acctgagctt
     1981 gcccctccag ctagcactaa gcaacatctc gctgtggacg cctgtaaatt actgagaaat
     2041 gtgaaacgtg caatcttgaa actgaggtgt tagaaaactt gatctgtggt gttttgtttt
     2101 gttttttttc ttaaaacaac agcaacgtga tcttggctgt ctgtcatgtg ttgaagtcca
     2161 tggttgggtc ttgtgaagtc tgaggtttaa cagtttgttg tcctggaggg attttcttac
     2221 agcgaagact tgagttcctc caagtcccag aaccccaaga atgggcaaga aggatcaggt
     2281 cagccactcc ctggagacac agccttctgg ctgggactga cttggccatg ttctcagctg
     2341 agccacgcgg ctggtagtgc agccttctgt gaccccgctg tggtaagtcc agcctgccca
     2401 gggctgctga gggctgcctc ttgacagtgc agtcttatcg agacccaatg cctcagtctg
     2461 ctcatccgta aagtggggat agtgaagatg acacccctcc ccaccacctc tcataagcac
     2521 tttaggaaca cacagagggt agggatagtg gccctggccg tctatcctac ccctttagtg
     2581 accgccccca tcccggcttt ctgagctgat ccttgaagaa gaaatcttcc atttctgctc
     2641 tcaaacccta ctgggatcaa actggaataa attgaagaca gccaggggga tggtgcagct
     2701 gtgaagctcg ggctgattcc ccctctgtcc cagaaggttg gccagagggt gtgacccagt
     2761 taccctttaa cccccaccct tccagtcggg tgtgagggcc tgaccgggcc cagggcaagc
     2821 agatgtcgca agccctattt attcagtctt cactataact cttagagttg agacgctaat
     2881 gttcatgact cctggccttg ggatgcccaa gggatttctg gctcaggctg taaaagtagc
     2941 tgagccatcc tgcccattcc tggaggtcct acaggtgaaa ctgcaggagc tcagcataga
     3001 cccagctctc tgggggatgg tcacctggtg atttcaatga tggcatccag gaattagctg
     3061 agccaacaga ccatgtggac agctttggcc agagctcccg tgtggcatct gggagccaca
     3121 gtgacccagc cacctggctc aggctagttc caaattccaa aagattggct tgtaaacctt
     3181 cgtctccctc tcttttaccc agagacagca catacgtgtg cacacgcatg cacacacaca
     3241 ttcagtattt taaaagaatg ttttcttggt gccattttca ttttatttta ttttttaatt
     3301 cttggagggg gaaataaggg aataaggcca aggaagatgt atagctttag ctttagcctg
     3361 gcaacctgga gaatccacat accttgtgta ttgaacccca ggaaaaggaa gaggtcgaac
     3421 caaccctgcg gaaggagcat ggtttcagga gtttatttta agactgctgg gaaggaaaca
     3481 ggccccattt tgtatatagt tgcaacttaa actttttggc ttgcaaaata tttttgtaat
     3541 aaagatttct gggtaataat gagtccttcc ggtgttcagt attcttgtct ttgtgagtgc
     3601 gtcccggggc cgcctcgggg cctgcctgcc ctcctgccaa agcctggaag aggattgaat
     3661 ggaccccagg gtttggaaac aacctacagc atttgagccc ctcacgtagg ttttagagac
     3721 gtacaatttt tgtttgccct ggctcagaag gagccggtgt aaggttgaga taaaattcca
     3781 tatagacaac tgagtttgga tctcggctct gctgctttgt agctgtggga gttcaaacag
     3841 cacctctttg agacttgggc cccgcgtcgg cacaatgggg caggaatagt ccctgccagg
     3901 gtgactgtgt ggattcaagg aggttggaag cactgagccc acgcttggca ctgggtaggc
     3961 catcactgag gcttgtgtct ttccttcctg ccctgaccct gcatagctga gtctcgtggc
     4021 ctctcaccac tgatgggatc tcggacaccc ggctcaccct cctcctgggg cctcactttc
     4081 cttccccacc aaatgcagac atctaatgct tgtcctgtaa tatccttgcc agatgactga
     4141 tgtcaagtgc tggtttatag tgggtgctca ataaatgtta gtttcctttc tatccctcca
     4201 ttagatcatt aatgatatta gtgctaatta tgtaataaag ttaaggcata aatatgttaa
//
