LOCUS       XM_006720466            6821 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SIN3 transcription regulator family member
            A (SIN3A), transcript variant X2, mRNA.
ACCESSION   XM_006720466
VERSION     XM_006720466.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006720466.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6821
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..6821
                     /gene="SIN3A"
                     /gene_synonym="CHR15DELq24; DEL15Q24; WITKOS"
                     /note="SIN3 transcription regulator family member A;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 7 mRNAs, 58 ESTs, 1935 long SRA reads, 15
                     Proteins, and 98% coverage of the annotated genomic
                     feature by RNAseq alignments, including 18 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:25942"
                     /db_xref="HGNC:HGNC:19353"
                     /db_xref="MIM:607776"
     CDS             400..4221
                     /gene="SIN3A"
                     /gene_synonym="CHR15DELq24; DEL15Q24; WITKOS"
                     /codon_start=1
                     /product="paired amphipathic helix protein Sin3a isoform
                     X1"
                     /protein_id="XP_006720529.1"
                     /db_xref="GeneID:25942"
                     /db_xref="HGNC:HGNC:19353"
                     /db_xref="MIM:607776"
                     /translation="MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAV
                     SETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSH
                     AHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSID
                     TPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQP
                     QPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPR
                     SPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHT
                     YQKEQRNAKEAGGNYTPALTEQEVYAQVARLFKNQEDLLSEFGQFLPDANSSVLLSKT
                     TAEKVDSVRNDHGGTVKKPQLNNKPQRPSQNGCQIRRHPTGTTPPVKKKPKLLNLKDS
                     SMADASKHGGGTESLFFDKVRKALRSAEAYENFLRCLVIFNQEVISRAELVQLVSPFL
                     GKFPELFNWFKNFLGYKESVHLETYPKERATEGIAMEIDYASCKRLGSSYRALPKSYQ
                     QPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLE
                     TNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIID
                     GLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQND
                     TKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHV
                     KRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMDVDEATGAVKKHNG
                     VGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAE
                     RQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDG
                     NIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNN
                     GATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEEN
                     SDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKE
                     GKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSK
                     RLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKY
                     RVKYGTVFKAP"
ORIGIN      
        1 aacagagaag cggccgcggc ggtagaggcg gcggagacgg tttctccatc ttcccccctc
       61 cccttccccc ctcggagttt ccctccctcc ctccctccct ccttcccagt ctgggcaccg
      121 gagcctgtga ccgcttcgtt agtggagagg tagctggcag tccgcttcgg cgggcctgtg
      181 ccccgcgccg ttctcggggc ctccctgctg agctcgcggc tcacgctgag agggacacgc
      241 agtgacgagc ggccgaagca gctttgcggc tcgagtgcag tagcgagatc tcagctcacc
      301 tcagcctctg tctcctggac tcacatgatc ctcccacgtc agcctcctaa atagctggga
      361 ttacaggttt tgtagtgcat ccctgagcat gagcacagaa tgaagcggcg tttggatgac
      421 caggagtcac cggtgtatgc agcccagcag cgtcggatcc ctggcagcac agaggctttt
      481 cctcaccagc accgggtgct tgcccctgcc cctcctgtgt atgaagcagt gtctgagacc
      541 atgcagtcag ctacgggaat tcagtactct gtaacaccca gctaccaggt ttcagccatg
      601 ccacagagct ccggcagtca tgggcccgct atagcagcag ttcatagcag ccatcatcac
      661 ccaacagcgg tgcagcccca cggaggccag gtggtccaga gtcatgctca tccagcccca
      721 ccagttgcac cagtgcaggg acagcagcaa tttcagaggc tgaaggtgga ggatgcgcta
      781 tcttatcttg accaggtgaa gctgcagttt ggtagtcagc ctcaggtcta caatgatttc
      841 cttgacatca tgaaggaatt taaatctcag agcatcgaca ccccaggagt gattagtcgt
      901 gtgtcccagc tattcaaagg ccaccccgat ctgataatgg gattcaacac cttcttgccc
      961 cctggctaca aaattgaggt gcaaaccaat gacatggtga atgtgacaac tcctggccag
     1021 gttcatcaga ttcccaccca tggcatccag ccacagcctc aaccaccacc ccaacatcct
     1081 tcccagcctt cagcccagtc agccccagct cctgcccagc cagctcctca gcccccacct
     1141 gccaaagtca gcaagccctc ccaactgcaa gcacatactc cggccagtca gcagactccc
     1201 ccacttccac cgtatgcatc cccacgttct ccgccggtcc agcctcacac accagtgaca
     1261 atctcgttgg gaacggcccc atccttgcag aacaatcaac ctgtggagtt taatcatgcc
     1321 atcaactatg ttaataagat caagaacaga tttcagggcc aaccagacat ctacaaagca
     1381 ttcctggaga ttttgcacac atatcagaaa gagcagagaa atgccaagga agctggagga
     1441 aactacactc cagcattgac agagcaggag gtgtatgccc aggttgctcg tctctttaaa
     1501 aaccaggaag atttgttgtc agagtttgga caattcctac cagatgccaa cagctccgtg
     1561 cttttaagca aaacaactgc tgagaaggtt gattctgtga gaaatgatca tggaggcact
     1621 gtcaagaagc cccaactgaa caacaagccg cagaggccca gccagaatgg ctgccagatc
     1681 cgcagacatc ctacaggaac cacccctcca gttaagaaga aacccaaact gctcaatctg
     1741 aaggattctt ctatggcaga tgccagcaaa catggtggtg gaacagaatc gttatttttt
     1801 gataaggtcc gaaaggctct tcggagtgca gaagcctacg aaaatttcct acgctgtctt
     1861 gttattttta accaggaggt gatctctcgt gctgagcttg tgcaactagt ctctcctttc
     1921 ctggggaaat tccctgagtt gtttaattgg tttaaaaact ttctgggcta taaggagtct
     1981 gtacatctgg aaacttatcc aaaggagcga gccacagagg gcattgctat ggagatagat
     2041 tatgcttctt gtaaacgatt gggctccagc tatcgagcct taccaaagag ttaccagcag
     2101 cccaagtgta caggacggac tcctctctgt aaagaggttt taaatgatac ctgggtttcc
     2161 ttcccttcgt ggtctgagga ctctaccttt gtgagttcca agaagactca atatgaagaa
     2221 catatttatc gttgtgaaga tgaacgcttt gagcttgatg tagttttaga gaccaatctg
     2281 gcaacaatcc gggttctgga agcaatacag aagaagcttt cccgcttgtc tgctgaagaa
     2341 caagccaaat ttcgcttgga caacaccctt gggggcacat cagaagtcat ccatagaaaa
     2401 gcactccaga ggatatatgc tgataaagca gctgacatca ttgatggtct gagaaagaat
     2461 ccctccattg ctgttccaat tgtccttaaa aggttgaaga tgaaagagga agaatggcga
     2521 gaagctcaga gaggctttaa caaagtatgg cgagaacaaa atgagaaata ctacttgaag
     2581 tctctggacc accaggggat caactttaaa cagaatgaca ccaaggtcct gaggtctaag
     2641 agcttactca atgagattga gagtatctat gatgagaggc aagagcaggc tacggaggag
     2701 aatgctggtg tacctgttgg cccacacctc tcacttgcgt atgaagacaa acaaatactg
     2761 gaagatgctg ctgctctgat tatccaccat gtgaagaggc agacaggcat tcagaaggag
     2821 gacaaatata agataaaaca aatcatgcat cattttattc cagatttgct ctttgcccaa
     2881 agaggtgatc tctcagatgt ggaggaagag gaagaagaag agatggatgt agatgaagcc
     2941 acaggggcag ttaagaagca caatggtgtt gggggcagtc cccctaagtc caagttactg
     3001 tttagtaaca cagcagctca aaaattaaga ggaatggatg aagtatacaa cctcttctat
     3061 gtcaacaaca actggtatat ttttatgcga ctgcaccaga ttctctgcct gaggctgcta
     3121 cggatttgtt cccaagccga acggcaaatt gaagaagaaa accgagagag agaatgggaa
     3181 cgggaagtgc tgggcataaa gcgagacaag agtgacagcc ctgccattca gctacgtctc
     3241 aaagaaccta tggatgttga tgtagaagat tattacccag ctttcctgga catggtgcgg
     3301 agcctgctgg atggcaacat agactcatca cagtatgaag attcactgag agagatgttc
     3361 accattcatg cctacattgc ctttaccatg gacaaactga tccagagcat tgtcagacag
     3421 ctgcagcata tcgtgagtga tgagatctgt gtgcaggtga ctgaccttta cctggcagaa
     3481 aataataatg gggccaccgg aggccagctg aacacacaga actcaaggag cctcctggag
     3541 tcaacgtatc agcggaaagc tgagcagcta atgtcagatg agaattgctt taagcttatg
     3601 tttattcaga gccaaggcca ggtccagctg actattgagc ttctggacac agaagaggag
     3661 aattcggatg accctgtgga agcagagcgc tggtcagact acgtggagcg atacatgaat
     3721 tcagatacta cctcgcctga gcttcgtgaa catctagcac agaaaccagt atttctcccc
     3781 aggaatctac ggcggatccg gaagtgtcaa cgtggtcgag agcagcagga aaaggaaggg
     3841 aaggaaggaa acagcaagaa gaccatggag aatgtggata gtctggataa gctggagtgt
     3901 agattcaagc tgaattccta caagatggtg tatgtgatca aatcagagga ctatatgtat
     3961 cggaggaccg ccctgctccg ggctcatcag tcccatgagc gtgtaagcaa gcgtctacat
     4021 cagagattcc aggcctgggt agataaatgg accaaggagc atgtgccccg tgaaatggca
     4081 gcagagacca gcaagtggct catgggtgag gggctggagg gcctggtgcc ctgtaccacc
     4141 acctgtgata cagagaccct gcattttgtg agcattaaca agtatcgtgt caaatacggc
     4201 acagtattca aagcccctta actgcaaagc cagagcagat aacttggggt gtgtgtgggg
     4261 atgtgtgtgt gggcctatgc actcacacac tgaagaaaca aggaagatgc ctttcaagcc
     4321 tcactgggcc tctctgggac atggccacct gacctgtgtg tggctggtgc agcctggcac
     4381 caagtgggct acctgttagg aacatgaata ccttacaaag ctgaagctgg aacttttccc
     4441 aaagggtttt gggtatagcc tgccctggag gggaaggaag tccatgcaag caaagacatg
     4501 cagtttgctt gcacacacca gcagagctaa gactggagtc tcctgtggcc taactttcaa
     4561 tgagggaacc ggatgctgtt cacactttga ctggatggag atgcatttac aaaacagact
     4621 ggagaaggac ttaatactca gatggattgg aactatcatg gtcactgctc ctctcccctc
     4681 cccacaaaag gaaaaaaaag ctggatttga tttttttttt ctggtcactc gagcacatct
     4741 aagatcaccc attaggtttt atctgggacc tgcagtttgg ctttgggatt gatcatcttg
     4801 tggattttat tcctgacgat tcccttgctg cctacccttt tctctcctct ggttctcaac
     4861 ctcaacgagt tcaaatcagt tgtccttttt agctcccgtg gaactgtttt gtatctgcct
     4921 ctttactagt ctaccttagt gccatccacc agctttactc tctgacacac acacgcacac
     4981 acacacacaa ttttaacttg tttttttgta cataatgtac atactgtcaa ttttttatta
     5041 aaagaaatat gctttgatgt gctagcataa ctgctctagc ttcttgtgta ccatagtact
     5101 gtggcttcag atttagtacc tatgaacaga tgtacaagac atttattaca ctttttacca
     5161 aagggagtta ccattgtagt acttttgtgt aaaacttgtc ttcccctttg cccccaactt
     5221 tttttttttt ttttttgtaa ataaataaag cttggttctt acttaaggaa taaactctca
     5281 acccacgtcc cttgtcctca ccagaaaata ctgtgaagca gggattttga cttcagttcc
     5341 ttatccaggg tagaaacagg attttgctta aaatacttgt tacttgtccc aaatcaaaat
     5401 attccaaaat cttagaatac ttaagtcttt tagtacgtgt ttttttccct tgttcaaata
     5461 atctgaaaat attttatatt tgggtaagtt gtcaagctat gtagtttgta tttctatata
     5521 ttttttctta ttcacattgg tgatggatgg gggtgagcaa cttaaatacc aaaccagtgt
     5581 ttgaaaaaaa agtgtgcata aggcatgtgg tataccttat aaatggagtt gggagggaga
     5641 gaatttgaaa tgggatacct atttttttaa ttacataaat ttaaactagc agacatttaa
     5701 acatgaatga ttaggatttt tctatgtggt taacctggac tttctgaaca aagaccaact
     5761 gagcccctcc cagtactctg gtggattttt cttcagcaac cattacgcaa gtcttagttg
     5821 taaccagcaa tgttctgtgt gttttatgtt tgctttttag ttaaaaatca ccaccaccac
     5881 caaaaagaaa aacaaaattt tttggctcct ggattttcaa aacacatggt agacctctct
     5941 gattttaggc ttttattgtt taaagacagt gtctcgcttt atgacccaca ctggagtgca
     6001 gtgccacgat catagctcac tgcaggcttg acctcccagg ctcaagcagt cctcccacct
     6061 cggcctcctg agtagctgca tgccaccacg cccagctaat tttttaactt tttgtagaga
     6121 cagggtcttg ctatgctgcc caggttggtc tcaaactcct ggcctcaagc tgtcctccca
     6181 cctcggcctc gcaaagtgct gagattacag gtgtgagcca ccctggcctg attttaggct
     6241 ttttttgtac tggggagaag agactgtgag ccaaagtgta gggtgccaaa aagagctttg
     6301 tgggatgaga ttttagggca aagctggggc agtgtctgac ttggcggtgg tcatgtgtac
     6361 tgatttaggg gaaagatctt gaggttttct caaataattc acctatcccc gtgttccctc
     6421 aagaaaggtc atgttgacct ggaaccatag gggaaattgg tggggtgtga tcagggtcag
     6481 ccccagctgt tgctgcccct gcagtgtttt gtccagagca cttgcctgca ggtcaggata
     6541 ggatttcaag gccagttcag gagaaagtcc caacccacca gtgcaaccaa caaaagagta
     6601 agttttacct acagcctggg ttttcacaag tagcattttt attcctcctg ctgtctgaca
     6661 tctgagctcc aagctctaaa cccaacctgt attatatgca gcagcaggtt atctttgttt
     6721 taaatcacat ttgttattct gtacttagtc acctttccgt gtgatctgca tttgaaatgt
     6781 tgtaaacttg gtcagtattt ccattaaaat atcagggcta a
//
