LOCUS       XM_011513078            5936 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens sucrase-isomaltase (SI), transcript variant
            X4, mRNA.
ACCESSION   XM_011513078
VERSION     XM_011513078.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011513078.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5936
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..5936
                     /gene="SI"
                     /note="sucrase-isomaltase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 16
                     ESTs, 14 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     18 samples with support for all annotated introns"
                     /db_xref="GeneID:6476"
                     /db_xref="HGNC:HGNC:10856"
                     /db_xref="MIM:609845"
     CDS             88..5472
                     /gene="SI"
                     /codon_start=1
                     /product="sucrase-isomaltase, intestinal isoform X2"
                     /protein_id="XP_011511380.1"
                     /db_xref="GeneID:6476"
                     /db_xref="HGNC:HGNC:10856"
                     /db_xref="MIM:609845"
                     /translation="MFFPPPEISDSTSTPATTRVTTNPSDSGKCPNVLNDPVNVRINC
                     IPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAKLNRIPS
                     PTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVK
                     VAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRH
                     DLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPT
                     PIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDV
                     VKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVII
                     LDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCI
                     DWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYS
                     KTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAA
                     HWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYP
                     FSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVAR
                     PVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPW
                     RKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFF
                     WDDGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTE
                     VRVAENNQPMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDA
                     DLATEQKCTQRGCVWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTAN
                     ARIKLPSDPISTLRVEVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLY
                     DVEIKENPFGIQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTA
                     FKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQP
                     TPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTS
                     EVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIII
                     LDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDKTLTEDEAV
                     NASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCR
                     NDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHD
                     ALQKTTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTG
                     ADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNI
                     RYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPY
                     VQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTF
                     YSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLYLSVQFNLNQTTLTSTILKR
                     GYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNEDTTNMILRIDLTTHNVT
                     LEEPIEINWS"
ORIGIN      
        1 aaatctctct gattgtcctt tttgtcatag ttactataat agctattgcc ttaattgttg
       61 ttttagcaac taagacacct gctgttgatg ttttttcctc ccccagaaat tagtgattct
      121 acttcaactc cagctactac tcgtgtgact acaaatcctt ctgattcagg aaaatgtcca
      181 aatgtgttaa atgatcctgt caatgtgaga ataaactgca ttccagaaca attcccaaca
      241 gagggaattt gtgcacagag aggctgctgc tggaggccgt ggaatgactc tcttattcct
      301 tggtgcttct tcgttgataa tcatggttat aacgttcaag acatgacaac aacaagtatt
      361 ggagttgaag ccaaattaaa caggatacct tcacctacac tatttggaaa tgacatcaac
      421 agtgttctct tcacaactca aaatcagaca cccaatcgtt tccggttcaa gattactgat
      481 ccaaataata gaagatatga agttcctcat cagtatgtaa aagagtttac tggacccaca
      541 gtttctgata cgttgtatga tgtgaaggtt gcccaaaacc catttagcat ccaagttatt
      601 aggaaaagca acggtaaaac tttgtttgac accagcattg gtcccttagt gtactctgac
      661 cagtacttac agatctcaac ccgtcttcca agtgattata tttatggtat tggagaacaa
      721 gttcataaga gatttcgtca tgatttatcc tggaaaacat ggccaatttt tactcgagac
      781 caacttcctg gtgataataa taataattta tacggccatc aaacattctt tatgtgtatt
      841 gaagatacat ctggaaagtc attcggtgtt tttttaatga atagcaatgc aatggagatt
      901 tttatccagc ctactccaat agtaacatat agagttaccg gtggcattct ggatttttac
      961 atccttctag gagatacacc agaacaagta gttcaacagt atcaacagct tgttggacta
     1021 ccagcaatgc cagcatattg gaatcttgga ttccaactaa gtcgctggaa ttataagtca
     1081 ctagatgtag tgaaagaagt ggtaaggaga aaccgggaag ctggcatacc atttgataca
     1141 caggtcactg atattgacta catggaagac aagaaagact ttacttatga tcaagttgcg
     1201 tttaacggac tccctcaatt tgtgcaagat ttgcatgacc atggacagaa atatgtcatc
     1261 atcttggacc ctgcaatttc cataggtcga cgtgccaatg gaacaacata tgcaacctat
     1321 gagaggggaa acacacaaca tgtgtggata aatgagtcag atggaagtac accaattatt
     1381 ggagaggtat ggccaggatt aacagtatac cctgatttca ctaacccaaa ctgcattgat
     1441 tggtgggcaa atgaatgcag tattttccat caagaagtgc aatatgatgg actttggatt
     1501 gacatgaatg aagtttccag ctttattcaa ggttcaacaa aaggatgtaa tgtaaacaaa
     1561 ttgaattatc caccgtttac tcctgatatt cttgacaaac tcatgtattc caaaacaatt
     1621 tgcatggatg ctgtgcagaa ctggggtaaa cagtatgatg ttcatagcct ctatggatac
     1681 agcatggcta tagccacaga gcaagctgta caaaaagttt ttcctaataa gagaagcttc
     1741 attcttaccc gctcaacatt tgctggatct ggaagacatg ctgcgcattg gttaggagac
     1801 aatactgctt catgggaaca aatggaatgg tctataactg gaatgctgga gttcagtttg
     1861 tttggaatac ctttggttgg agcagacatc tgtggatttg tggctgaaac cacagaagaa
     1921 ctttgcagaa gatggatgca acttggggca ttttatccat tttccagaaa ccataattct
     1981 gacggatatg aacatcagga tcctgcattt tttgggcaga attcactttt ggttaaatca
     2041 tcaaggcagt atttaactat tcgctacacc ttattaccct tcctctacac tctgttttat
     2101 aaagcccatg tgtttggaga aacagtagca agaccagttc ttcatgagtt ttatgaggat
     2161 acgaacagct ggattgagga cactgagttt ttgtggggcc ctgcattact tattactcct
     2221 gttctaaaac agggagcaga tactgtgagt gcctacatcc ctgatgctat ttggtatgat
     2281 tatgaatctg gtgcaaaaag gccatggagg aaacaacggg ttgatatgta tcttccagca
     2341 gacaaaatag gattacatct tagaggaggt tatatcatcc ccattcaaga accagatgta
     2401 acaacaacag caagccgtaa gaatcctcta ggacttatag tcgcattagg tgaaaacaac
     2461 acagccaaag gagacttttt ctgggatgat ggagaaacta aagatacaat acaaaatggc
     2521 aactacatat tatatacatt ttcagtttct aataacacat tagatattgt gtgcacacat
     2581 tcatcatatc aggaaggaac taccttagca tttcagactg taaaaatcct tgggttgaca
     2641 gacagtgtta cagaagttag agtggcggaa aataatcaac caatgaacgc tcattccaat
     2701 ttcacttatg atgcttctaa ccaggttctc ctaattgcag atctcaaact taatcttgga
     2761 agaaacttta gtgttcaatg gaatcaaatt ttctcagaaa atgaaagatt taattgttat
     2821 ccagatgcag atttggcaac tgaacaaaag tgcacacaac gtggctgtgt atggagaacg
     2881 ggttcttctc tatccaaagc acctgagtgt tactttccca gacaagataa ctcttattca
     2941 gtcaactcag ctcgctattc atccatgggt ataacagctg acctccaact aaatactgca
     3001 aatgccagaa taaagttacc ttctgacccc atctcaactc ttcgtgtgga ggtgaaatat
     3061 cacaaaaatg atatgttgca gtttaagatt tatgatcccc aaaagaagag atatgaagta
     3121 ccagtaccgt taaacattcc aaccacccca ataagtactt atgaagacag actttatgat
     3181 gtggaaatca aggaaaatcc ttttggcatc cagattcgac ggagaagcag tggaagagtc
     3241 atttgggatt cttggctgcc tggatttgct tttaatgacc agttcattca aatatcgact
     3301 cgcctgccat cagaatatat atatggtttt ggggaagtgg aacatacagc atttaagcga
     3361 gatctgaact ggaatacttg gggaatgttc acaagagacc aaccccctgg ttacaaactt
     3421 aattcctatg gatttcatcc ctattacatg gctctggaag aggagggcaa tgctcatggt
     3481 gttttcttac tcaacagcaa tgcaatggat gttacattcc agccaactcc tgctctaact
     3541 taccgtacag ttggagggat cttggatttt tatatgtttt tgggcccaac tccagaagtt
     3601 gcaacaaagc aataccatga agtaattggc catccagtca tgccagctta ttgggctttg
     3661 ggattccaat tatgtcgtta tggatatgca aatacttcag aggttcggga attatatgac
     3721 gctatggtgg ctgctaacat cccctatgat gttcagtaca cagacattga ctacatggaa
     3781 aggcagctag actttacaat tggtgaagca ttccaggacc ttcctcagtt tgttgacaaa
     3841 ataagaggag aaggaatgag atacattatt atcctggatc cagcaatttc aggaaatgaa
     3901 acaaagactt accctgcatt tgaaagagga cagcagaatg atgtctttgt caaatggcca
     3961 aacaccaatg acatttgttg ggcaaaggtt tggccagatt tgcccaacat aacaatagat
     4021 aaaactctaa cggaagatga agctgttaat gcttccagag ctcatgtagc tttcccagat
     4081 ttcttcagga cttccacagc agagtggtgg gccagagaaa ttgtggactt ttacaatgaa
     4141 aagatgaagt ttgatggttt gtggattgat atgaatgagc catcaagttt tgtaaatgga
     4201 acaactacta atcaatgcag aaatgacgaa ctaaattatc caccttattt cccagaactc
     4261 acaaaaagaa ctgatggatt acatttcaga acaatttgca tggaagctga gcagattctt
     4321 agtgatggaa catcagtttt gcattacgat gttcacaatc tctatggatg gtcacagatg
     4381 aaacctactc atgatgcatt gcagaagaca actggaaaaa gagggattgt aatttctcgt
     4441 tccacgtatc ctactagtgg acgatgggga ggacactggc ttggagacaa ctatgcacga
     4501 tgggacaaca tggacaaatc aatcattggt atgatggaat ttagtctgtt tggaatgtca
     4561 tatactggag cagacatctg tggttttttc aacaactcag aatatcatct ctgtacccgc
     4621 tggatgcaac ttggagcatt ttatccatac tcaaggaatc acaacattgc aaatactaga
     4681 agacaagatc ccgcttcctg gaatgaaact tttgctgaaa tgtcaaggaa tattctaaat
     4741 attagataca ccttattgcc ctatttttac acacaaatgc atgaaattca tgctaatggt
     4801 ggcactgtta tccgacccct tttgcatgag ttctttgatg aaaaaccaac ctgggatata
     4861 ttcaagcagt tcttatgggg tccagcattt atggttaccc cagtactgga accttatgtt
     4921 caaactgtaa atgcctacgt ccccaatgct cggtggtttg actaccatac aggcaaagat
     4981 attggcgtca gaggacaatt tcaaacattt aatgcttctt atgacacaat aaacctacat
     5041 gtccgtggtg gtcacatcct accatgtcaa gagccagctc aaaacacatt ttacagtcga
     5101 caaaaacaca tgaagctcat tgttgctgca gatgataatc agatggcaca gggttctctg
     5161 ttttgggatg atggagagag tatagacacc tatgaaagag acctatattt atctgtacaa
     5221 tttaatttaa accagaccac cttaacaagc actatattga agagaggtta cataaataaa
     5281 agtgaaacga ggcttggatc ccttcatgta tgggggaaag gaactactcc tgtcaatgca
     5341 gttactctaa cgtataacgg aaataaaaat tcgcttcctt ttaatgaaga cactaccaac
     5401 atgatattac gtattgatct gaccacacac aatgttactc tagaagaacc aatagaaatc
     5461 aactggtcat gaagatcacc atcaatttta gttgtcaatg ggaaaaaaca ccaggattta
     5521 agtttcacag cacttacaat tttccctctt cacttggttc ttgtactcta caaaatatag
     5581 ctttcataac atcgaaaagt tattttgtag cgtacatcaa tgataatgct aattttatta
     5641 tagtaatgtg acttggattc aattttaagg catatttaac aaaatttgaa tagccctatt
     5701 tatccttgtt aagtatcagc tacaattgta aactagttac taaacatgta tgtaaatagc
     5761 taagatataa tttaaacgtg atttttaaat taaataaaat ttttatgtaa ttatatatac
     5821 tatatttttc tcaatgttta gcagatttaa gatatgtaac aacaattatt tgaagattta
     5881 attacttctt agtatgtgca tttaattaga aaaagagaat aaaaaatgta agtgta
//
