LOCUS       XM_047448731            4515 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SHOX homeobox 2 (SHOX2), transcript variant
            X3, mRNA.
ACCESSION   XM_047448731
VERSION     XM_047448731.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4515
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4515
                     /gene="SHOX2"
                     /gene_synonym="OG12; OG12X; SHOT"
                     /note="SHOX homeobox 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 5 ESTs, 99 long SRA
                     reads, 5 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:6474"
                     /db_xref="HGNC:HGNC:10854"
                     /db_xref="MIM:602504"
     CDS             1779..2393
                     /gene="SHOX2"
                     /gene_synonym="OG12; OG12X; SHOT"
                     /codon_start=1
                     /product="short stature homeobox protein 2 isoform X2"
                     /protein_id="XP_047304687.1"
                     /db_xref="GeneID:6474"
                     /db_xref="HGNC:HGNC:10854"
                     /db_xref="MIM:602504"
                     /translation="MSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLF
                     DETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEAC
                     RVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLA
                     TLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL"
ORIGIN      
        1 acacaattcc tttagtgttt tcaatcaccc agtactcggt tctcttagag caaaaatcct
       61 ttggtgctag ctcagtgtta ggaaacgtct ttatctcaat ggcagagcgt tctataccaa
      121 ttcaaaggag ttcaacaata aaattgattt ggcacttggt gcctgcagta actggtgtac
      181 tgccatattt ttccaattaa gaaaatatgt ggcatgcgtg gaatcacata tttaagcaag
      241 caattaagtt gtttatgaca cggtctgttc ctgtttagat cagtaattgg aaatttgggg
      301 acaaaaatag agattttatt aagtctatgg atcaacttga aatttggaca tctcctcgaa
      361 gccccaaaac tttgagtggc atccactgtg tagatgacat gtaatagaca aagccttccc
      421 acctcattgg cagaatttga agggtgtgtt ttcatattta aatttcaata caatatcagt
      481 aaaaatactt tgctattaaa ttggcccata atgtttacta taatgttcct tcctaaagaa
      541 aggacaaatg tccacaaaac taactctgag aactagaaaa tacggcaata tttaagatca
      601 ccgtagctag aatgcccggc agggccgaga tctagcgact cttcttcctc caaaccagca
      661 ccaggtcttc ctaaatttgt aaagtggtgg agttaccgtc aaggtgccca gtgcagcctc
      721 ccggccatga gtccacaact acaggcccga actacaggtt cgccagcgcg cctgacggcg
      781 aggttcaggt ctgaaccccc ggcgggcgca gttcctggga ttgttgattt ccaagctcag
      841 ggcaagtatt aatttctctg cagaccggct cttccggaaa tgatttttaa cacccatgct
      901 ggcctggatc ctgcgctggg aagaactgca aacagcctcg actatctaaa ctcagctttg
      961 acttcttaaa acccggagtc tctgattcgg gcgcagagga taaaggttcc agggggatat
     1021 atatatggtg gctgtatatg ctcacactag aagagctcct gtttttaaag ggaggagaag
     1081 gacaggaaag tggcaacgga tgtgtgcaaa cccagagcag aaaaattcat attttattaa
     1141 acatccgagc tgctggttgc atgaaaaggc tttgagcaac caatagaaac cgaggatcgc
     1201 gaatattccg cttgaacctg ttgatctctg tgggttaagc gtttagggtc gagtctgcgt
     1261 ttccacgagg gagggcgaag agagaacaga aagagcggtt gctttcgccc gccaccggag
     1321 gctggttttc cgcctcctgc cttctggccc ggcttgggcg gcgagccctt tgggcagcca
     1381 acatggcgtg ggcgcctgtg ctcgtgcgac cccggtcggg caggcgggac ggagattacc
     1441 tggctgtcca ggggacctta tgcagggttt ggcccgagcc caggggcagc gaggggcgtc
     1501 tgcggatgcg gctccctgtg cggcacaaca ccggggtctg ttgctctcgc tgataccttt
     1561 cggcccaatt gttcctaaat tagaccagca agtttgcggt aggcagagag ccagcggtgg
     1621 tgagagctgg cctgagaacg agccagcctt ctgggaatgg ccggtgtgag aggccagtgg
     1681 gtggccttgc cgcgccctta tgtccagact ttgctctgtg agaggcctgg cgctgcgcct
     1741 ttgatttctg tgagtgctgc ggagcaagtg agtgcgaaat gtccccggag ctgaaagatc
     1801 gcaaagagga tgcgaaaggg atggaggacg aaggccagac caaaatcaag cagaggcgaa
     1861 gtcggaccaa tttcaccctg gaacaactca atgagctgga gaggcttttt gacgagaccc
     1921 actatcccga cgccttcatg cgagaggaac tgagccagcg actgggcctg tcggaggccc
     1981 gagtgcaggt ttggtttcaa aatcgaagag ctaaatgtag aaaacaagaa aatcaactcc
     2041 ataaaggtgt tctcataggg gccgccagcc agtttgaagc ttgtagagtc gcaccttatg
     2101 tcaacgtagg tgctttaagg atgccatttc agcaggttca ggcgcagctg cagctggaca
     2161 gcgctgtggc gcacgcgcac caccacctgc atccgcacct ggccgcgcac gcgccctaca
     2221 tgatgttccc agcaccgccc ttcggactgc cgctcgccac gctggccgcg gattcggctt
     2281 ccgccgcctc ggtagtggcg gccgcagcag ccgccaagac caccagcaag aactccagca
     2341 tcgccgatct cagactgaaa gccaaaaagc acgccgcagc cctgggtctg tgacgccaac
     2401 gccagcacca atgtcgcgcc tgtcccgcgg cactcagcct gcacgccctc cgcgccccgc
     2461 tgcttctccg ttaccccttt gagacctcgg gagccggccc tcttcccgcc tcactgacca
     2521 tccctcgtcc cctatcgcat cttggactcg gaaagccaga ctccacgcag gaccagggat
     2581 ctcacgaggc acgcaggctc cgtggctcct gcccgttttc ctactcgagg gcctagaatt
     2641 gggttttgta ggagcgggtt tgggggagtc tggagagaga ctggacaggg gagtgctgga
     2701 accgcggagt ttggctcacc gcaaagctgc aacgatggac tcttgcatag aaaaaaaaat
     2761 cttgttaaca atgaaaaaat gagcaaacaa aaaaatcgaa agacaaacgg gagagaaaaa
     2821 gaggaaggga acttatttct taactgctat ttggcagaag ctgaaattgg agaaccaagg
     2881 agcaaaaaca aattttaaaa ttaaagtatt ttatacattt aaaaatatgg aaaaacaacc
     2941 cagacgattc tcgagagact ggggggagtt accaacttaa atgtgtgttt ttaaaaatgc
     3001 gctaagaagg caaagcagaa agaagaggta tacttattta aaaaactaag atgaaaaaag
     3061 tgcgcagctg ggaagttcac aggttttgaa actgaccttt ttctgcgaag ttcacgttaa
     3121 cacgagaaat ttgatgagag aggcgggcct ccttttacgt tgaatcagat gctttgagtt
     3181 taaacccacc atgtatggaa gagcaagaaa agagaaaata ttaaaacgag gagagagaaa
     3241 aataatatta acacaaaaaa atgccacaga caatgatttc tctgagaaat tattatggca
     3301 aaactgtctg gactgctgac agtaaattcc ggtttgcatg ttacttgtat tccattgatg
     3361 gtgtgtctcc tcccaccccc ttatctccca tgcactcact ccattttcat cttcactatg
     3421 aaaaacaata ccaaaagtat ctggaaattg atatatatat atccatatat atatatcata
     3481 tatttgccat atatatatat atatatatat atatatatat atatatatat ttgccctgtc
     3541 tttgatcctg gggaacaaaa gaaaaaagtc agaaagggaa aaaattacac tcattgtcct
     3601 aagaagacag aggtgggcag aatatgtggg gaaaggaaaa agaaaacaag accaccaaat
     3661 gaaataatga aggtacagcg cctcgctgtg ccagacacag taggcgctca atcagtatta
     3721 gttcccacca ttcccctttt cttgtgttcc ttcttgttgg tttcctgaag tcctatttga
     3781 agacagtggt ttatttcccc ctctctatcc cgtcaaattc accttaaata acacccagct
     3841 agatacaggc actaggtttg tgtaagatat gttgatacac acgaacaaag tttattttga
     3901 ctataatgtg tggactgact ttcaacattt gcattttatc tcacaaaggt gtatctattc
     3961 aagtaacctt ttttttttgt ttgtttgttt cttttttgtt tttttttttc ttttggttgt
     4021 ttgtttcaat tcatgtagct atttaaactg ggataccttg gactaagcca gtctgtatcc
     4081 caattcgcta gcaagcctaa gtttgtgggg ttttgttttt gtttttgttt taccttctaa
     4141 tttacaagaa agaggaaaag ctcttctaac tgaactttgg tatgcggttg agctttgtaa
     4201 ctatttgttc tccatgaaaa caaaattatt tatatttgac atattttttt ctagtgtatt
     4261 aagttatttt aaacaaaaga tgttatctca tgacgtgttg tcagtacaaa atgtgtcgcc
     4321 tccaattctg ttaaaccttt taaataagtg ccaagttatt aattgaagac actttgcgat
     4381 caattgaatg aaaatatcgt ttcatttgat ggggttcgag tcatctttgt tcctgttact
     4441 attaaaatat ccgggatagt ctttcccttt tgattaatgc gtatcactct ctcgaatata
     4501 ccaacttgga aaagc
//
