LOCUS       NM_001164442             772 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens shisa like 2B (SHISAL2B), mRNA.
ACCESSION   NM_001164442 XM_001720158
VERSION     NM_001164442.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Beyer,A.L., Kaemmerer,D., Sanger,J. and Lupp,A.
  TITLE     Co-Expression of Adaptor Protein FAM159B with Different Markers for
            Neuroendocrine Cells: An Immunocytochemical and Immunohistochemical
            Study
  JOURNAL   Int J Mol Sci 23 (21), 13503 (2022)
   PUBMED   36362289
  REMARK    GeneRIF: Co-Expression of Adaptor Protein FAM159B with Different
            Markers for Neuroendocrine Cells: An Immunocytochemical and
            Immunohistochemical Study.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  AUTHORS   Beyer,A.L., Kaemmerer,D., Sanger,J., Evert,K. and Lupp,A.
  TITLE     Immunohistochemical Evaluation of Adaptor Protein FAM159B
            Expression in Normal and Neoplastic Human Tissues
  JOURNAL   Int J Mol Sci 22 (22), 12250 (2021)
   PUBMED   34830137
  REMARK    GeneRIF: Immunohistochemical Evaluation of Adaptor Protein FAM159B
            Expression in Normal and Neoplastic Human Tissues.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 772)
  AUTHORS   Pei,J. and Grishin,N.V.
  TITLE     Unexpected diversity in Shisa-like proteins suggests the importance
            of their roles as transmembrane adaptors
  JOURNAL   Cell Signal 24 (3), 758-769 (2012)
   PUBMED   22120523
REFERENCE   4  (bases 1 to 772)
  AUTHORS   Schmutz,J., Martin,J., Terry,A., Couronne,O., Grimwood,J.,
            Lowry,S., Gordon,L.A., Scott,D., Xie,G., Huang,W., Hellsten,U.,
            Tran-Gyamfi,M., She,X., Prabhakar,S., Aerts,A., Altherr,M.,
            Bajorek,E., Black,S., Branscomb,E., Caoile,C., Challacombe,J.F.,
            Chan,Y.M., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Glavina,T., Gomez,M., Gonzales,E., Goodstein,D.,
            Grigoriev,I., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Israni,S.,
            Jett,J., Kadner,K., Kimball,H., Kobayashi,A., Lopez,F., Lou,Y.,
            Martinez,D., Medina,C., Morgan,J., Nandkeshwar,R., Noonan,J.P.,
            Pitluck,S., Pollard,M., Predki,P., Priest,J., Ramirez,L.,
            Retterer,J., Rodriguez,A., Rogers,S., Salamov,A., Salazar,A.,
            Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N., Wheeler,J.,
            Wu,K., Yang,J., Dickson,M., Cheng,J.F., Eichler,E.E., Olsen,A.,
            Pennacchio,L.A., Rokhsar,D.S., Richardson,P., Lucas,S.M.,
            Myers,R.M. and Rubin,E.M.
  TITLE     The DNA sequence and comparative analysis of human chromosome 5
  JOURNAL   Nature 431 (7006), 268-274 (2004)
   PUBMED   15372022
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ271827.1, BU785751.1 and BU952508.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001164442.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU952508.1, BU951066.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142586, SAMEA2149398
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000389074.6/ ENSP00000373726.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                BQ271827.1         196-220
            26-609              BU785751.1         1-584
            610-772             BU952508.1         3-165               c
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q12.3"
     gene            1..772
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /note="shisa like 2B"
                     /db_xref="GeneID:100132916"
                     /db_xref="HGNC:HGNC:34236"
                     /db_xref="MIM:620219"
     exon            1..312
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..604
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /note="membrane protein FAM159B; family with sequence
                     similarity 159 member B"
                     /codon_start=1
                     /product="protein shisa-like-2B"
                     /protein_id="NP_001157914.1"
                     /db_xref="CCDS:CCDS47220.1"
                     /db_xref="GeneID:100132916"
                     /db_xref="HGNC:HGNC:34236"
                     /db_xref="MIM:620219"
                     /translation="MSEASRLCSGYYSLNQSFVEPFQCPRRGEGAALQYCCGFADLKY
                     CCSEPGSYFPYKHSYMWSLSIGALIGLGIAALVLLAFVISVCVLCYLFLYTKPQRLDT
                     GLKLQHLEASSTQEGKSNGKTKALNSNAASNATNETYYEADDIIQEKTMDATQIHIAY
                     "
     exon            313..470
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /inference="alignment:Splign:2.1.0"
     exon            471..772
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      653..658
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /note="hexamer: AATAAA"
     polyA_site      672
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /note="major polyA site"
     regulatory      752..757
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
                     /note="hexamer: ATTAAA"
     polyA_site      772
                     /gene="SHISAL2B"
                     /gene_synonym="FAM159B"
ORIGIN      
        1 agagcccaga tcggaagagc cgagtccggg cagaggggtc cgcgggctct ggaggtgctg
       61 gacgggtgcg atccgagagc agaccggggc cctcgcgagc ctctcccggc ccctgcccgc
      121 gatgagcgag gccagccgac tgtgctccgg ctactacagc ctcaaccaga gcttcgtgga
      181 gcccttccag tgcccccggc gcggcgaggg ggcagcgctc cagtattgct gcggcttcgc
      241 cgacctcaag tactgctgca gcgagccggg cagctacttc ccctacaagc acagctacat
      301 gtggagcctc agcattggtg ccttgattgg actaggaatt gctgcccttg ttttactcgc
      361 ctttgtcatc agtgtctgtg tcctttgcta tttatttctg tatacgaaac ctcaaagatt
      421 agacactggc cttaagcttc aacacttaga ggcttcttcc actcaagaag gcaagtcaaa
      481 tggaaaaacc aaagccctca attcaaatgc agcatcaaat gcaacaaatg aaacatacta
      541 tgaagctgat gatataattc aagaaaaaac aatggatgca acacaaatcc acattgctta
      601 ttaactaaaa attctgtgtt ttaaatgctt actggagaga tgggacaata aaaataaagc
      661 gtgcacttga aacggtttgt aatattgctt ttcaaaaatt cgtcactcac aaagcaagac
      721 acagctgcat ttttgatcat tcagttactt tattaaacgc acattaaggt tt
//
