LOCUS       NM_207386               7625 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens shisa family member 6 (SHISA6), transcript variant 1,
            mRNA.
ACCESSION   NM_207386 XM_001716031 XM_001717728 XM_001718603
VERSION     NM_207386.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Ramos,J., Caywood,L.J., Prough,M.B., Clouse,J.E., Herington,S.D.,
            Slifer,S.H., Fuzzell,M.D., Fuzzell,S.L., Hochstetler,S.D.,
            Miskimen,K.L., Main,L.R., Osterman,M.D., Zaman,A.F.,
            Whitehead,P.L., Adams,L.D., Laux,R.A., Song,Y.E., Foroud,T.M.,
            Mayeux,R.P., St George-Hyslop,P., Ogrocki,P.K., Lerner,A.J.,
            Vance,J.M., Cuccaro,M.L., Haines,J.L., Pericak-Vance,M.A. and
            Scott,W.K.
  TITLE     Genetic variants in the SHISA6 gene are associated with delayed
            cognitive impairment in two family datasets
  JOURNAL   Alzheimers Dement 19 (2), 611-620 (2023)
   PUBMED   35490390
  REMARK    GeneRIF: Genetic variants in the SHISA6 gene are associated with
            delayed cognitive impairment in two family datasets.
REFERENCE   2  (bases 1 to 7625)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 7625)
  AUTHORS   Dichgans,M., Malik,R., Konig,I.R., Rosand,J., Clarke,R.,
            Gretarsdottir,S., Thorleifsson,G., Mitchell,B.D., Assimes,T.L.,
            Levi,C., O'Donnell,C.J., Fornage,M., Thorsteinsdottir,U.,
            Psaty,B.M., Hengstenberg,C., Seshadri,S., Erdmann,J., Bis,J.C.,
            Peters,A., Boncoraglio,G.B., Marz,W., Meschia,J.F., Kathiresan,S.,
            Ikram,M.A., McPherson,R., Stefansson,K., Sudlow,C., Reilly,M.P.,
            Thompson,J.R., Sharma,P., Hopewell,J.C., Chambers,J.C., Watkins,H.,
            Rothwell,P.M., Roberts,R., Markus,H.S., Samani,N.J., Farrall,M. and
            Schunkert,H.
  CONSRTM   METASTROKE Consortium; CARDIoGRAM Consortium; C4D Consortium;
            International Stroke Genetics Consortium
  TITLE     Shared genetic susceptibility to ischemic stroke and coronary
            artery disease: a genome-wide analysis of common variants
  JOURNAL   Stroke 45 (1), 24-36 (2014)
   PUBMED   24262325
  REMARK    Review article
REFERENCE   4  (bases 1 to 7625)
  AUTHORS   Verhoeven,V.J., Hysi,P.G., Wojciechowski,R., Fan,Q.,
            Guggenheim,J.A., Hohn,R., MacGregor,S., Hewitt,A.W., Nag,A.,
            Cheng,C.Y., Yonova-Doing,E., Zhou,X., Ikram,M.K., Buitendijk,G.H.,
            McMahon,G., Kemp,J.P., Pourcain,B.S., Simpson,C.L., Makela,K.M.,
            Lehtimaki,T., Kahonen,M., Paterson,A.D., Hosseini,S.M., Wong,H.S.,
            Xu,L., Jonas,J.B., Parssinen,O., Wedenoja,J., Yip,S.P., Ho,D.W.,
            Pang,C.P., Chen,L.J., Burdon,K.P., Craig,J.E., Klein,B.E.,
            Klein,R., Haller,T., Metspalu,A., Khor,C.C., Tai,E.S., Aung,T.,
            Vithana,E., Tay,W.T., Barathi,V.A., Chen,P., Li,R., Liao,J.,
            Zheng,Y., Ong,R.T., Doring,A., Evans,D.M., Timpson,N.J.,
            Verkerk,A.J., Meitinger,T., Raitakari,O., Hawthorne,F.,
            Spector,T.D., Karssen,L.C., Pirastu,M., Murgia,F., Ang,W.,
            Mishra,A., Montgomery,G.W., Pennell,C.E., Cumberland,P.M.,
            Cotlarciuc,I., Mitchell,P., Wang,J.J., Schache,M.,
            Janmahasatian,S., Igo,R.P. Jr., Lass,J.H., Chew,E., Iyengar,S.K.,
            Gorgels,T.G., Rudan,I., Hayward,C., Wright,A.F., Polasek,O.,
            Vatavuk,Z., Wilson,J.F., Fleck,B., Zeller,T., Mirshahi,A.,
            Muller,C., Uitterlinden,A.G., Rivadeneira,F., Vingerling,J.R.,
            Hofman,A., Oostra,B.A., Amin,N., Bergen,A.A., Teo,Y.Y., Rahi,J.S.,
            Vitart,V., Williams,C., Baird,P.N., Wong,T.Y., Oexle,K.,
            Pfeiffer,N., Mackey,D.A., Young,T.L., van Duijn,C.M., Saw,S.M.,
            Bailey-Wilson,J.E., Stambolian,D., Klaver,C.C. and Hammond,C.J.
  CONSRTM   Consortium for Refractive Error and Myopia (CREAM); Diabetes
            Control and Complications Trial/Epidemiology of Diabetes
            Interventions and Complications (DCCT/EDIC) Research Group;
            Wellcome Trust Case Control Consortium 2 (WTCCC2); Fuchs' Genetics
            Multi-Center Study Group
  TITLE     Genome-wide meta-analyses of multiancestry cohorts identify
            multiple new susceptibility loci for refractive error and myopia
  JOURNAL   Nat Genet 45 (3), 314-318 (2013)
   PUBMED   23396134
  REMARK    Erratum:[Nat Genet. 2013 Jun;45(2):712. Janmahasathian, Sarayut
            [corrected to Sarayut Janmahasatian]]
REFERENCE   5  (bases 1 to 7625)
  AUTHORS   Lauc,G., Huffman,J.E., Pucic,M., Zgaga,L., Adamczyk,B., Muzinic,A.,
            Novokmet,M., Polasek,O., Gornik,O., Kristic,J., Keser,T.,
            Vitart,V., Scheijen,B., Uh,H.W., Molokhia,M., Patrick,A.L.,
            McKeigue,P., Kolcic,I., Lukic,I.K., Swann,O., van Leeuwen,F.N.,
            Ruhaak,L.R., Houwing-Duistermaat,J.J., Slagboom,P.E., Beekman,M.,
            de Craen,A.J., Deelder,A.M., Zeng,Q., Wang,W., Hastie,N.D.,
            Gyllensten,U., Wilson,J.F., Wuhrer,M., Wright,A.F., Rudd,P.M.,
            Hayward,C., Aulchenko,Y., Campbell,H. and Rudan,I.
  TITLE     Loci associated with N-glycosylation of human immunoglobulin G show
            pleiotropy with autoimmune diseases and haematological cancers
  JOURNAL   PLoS Genet 9 (1), e1003225 (2013)
   PUBMED   23382691
REFERENCE   6  (bases 1 to 7625)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005725.1, DA362563.1, AK128003.1 and AC007510.6.
            
            On May 17, 2019 this sequence version replaced NM_207386.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2142586 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000441885.8/ ENSP00000390084.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-516               AC005725.1         13549-14064
            517-867             DA362563.1         1-351
            868-2222            AK128003.1         1-1355
            2223-7625           AC007510.6         17931-23333         c
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p12"
     gene            1..7625
                     /gene="SHISA6"
                     /note="shisa family member 6"
                     /db_xref="GeneID:388336"
                     /db_xref="HGNC:HGNC:34491"
                     /db_xref="MIM:617327"
     exon            1..848
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1866
                     /gene="SHISA6"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; protein shisa-6 homolog; shisa homolog 6"
                     /codon_start=1
                     /product="protein shisa-6 isoform 1 precursor"
                     /protein_id="NP_997269.2"
                     /db_xref="CCDS:CCDS45615.1"
                     /db_xref="GeneID:388336"
                     /db_xref="HGNC:HGNC:34491"
                     /db_xref="MIM:617327"
                     /translation="MALRRLLLLLLLSLESLDLLPSVHGARGRAANRTLSAGGAAVGG
                     RRAGGALARGGRELNGTARAPGIPEAGSRRGQPAAAVAAAASAAVTYETCWGYYDVSG
                     QYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKVVS
                     PGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIHRALADI
                     LRQQGPIPIAHCERETISAIDTSPKENTPVRSSSKNHYTPVRTAKQTPGHYGKDAYRS
                     GGPDLHNFISSGFVTLGRGHTKGDHQYNHPILSSVTQIPPHEKPRMNNILTSATEPYD
                     LSFSRSFQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTL
                     PLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPDRGLPDEFSMPYDRILSDEQLLSTE
                     RLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMSKMHSHPSASNNSYAT
                     LGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV"
     exon            849..1009
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1105
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1162
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1315
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..7625
                     /gene="SHISA6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7605..7610
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SHISA6"
                     /note="hexamer: AATAAA"
     polyA_site      7625
                     /gene="SHISA6"
                     /note="major polyA site"
ORIGIN      
        1 gagagcccga gcagcccgcg ccgggccggt ccgtgcgcac cgcgcgccgc cgccgccact
       61 gccgcccgcg cctcgatggc gccatcgccc cggagccgct gaccgctcag cgcctccagc
      121 ccggcccgcg cggcgggtcc tccgagcccg gcccgccggg ggagcggcct gccgcggaag
      181 cctccccgcg ccctcccgcc cggccccgcc atggcgctgc ggcgcctcct gctgctgctg
      241 ctgctctcgc tggagtccct ggacctgctg cccagcgtcc acggagcccg cggccgcgcc
      301 gccaaccgga ccctgagtgc aggcggcgct gccgtcgggg gccggagggc cgggggcgcc
      361 ctggcacggg gcggccgcga gctgaacggc accgcccggg cgcccggaat cccggaggcg
      421 ggaagccggc gggggcagcc cgcggcggct gtggcggcgg cggccagcgc ggccgtcacc
      481 tacgagacgt gctggggcta ctacgacgtg agcggccagt acgacaagga gttcgagtgt
      541 aacaacagcg agagcggcta cctgtactgc tgcggtacct gctactaccg cttctgctgc
      601 aagaagcgcc acgagaagct ggaccagcgc cagtgcacca actaccagag cccggtgtgg
      661 gtacagacgc ccagcaccaa ggtggtgtcg ccggggcccg agaacaagta cgacccggag
      721 aaggacaaga ccaacttcac cgtctacatc acctgcgggg tgatcgcctt cgtcatcgtg
      781 gccggcgtct tcgccaaggt ctcctacgac aaggcccacc gccctccacg ggagatgaac
      841 atccacaggg ctctggctga catcttaaga caacagggac caatccccat agcacactgt
      901 gaaagagaaa ctatctcggc tatcgatacc tctcccaaag agaacacgcc ggtcagatcg
      961 tcctccaaaa accactacac tcctgtgcgt acggccaagc agactccagg gcattatggg
     1021 aaggatgctt accgaagtgg aggacctgat ctccataact tcatctcatc tggatttgtc
     1081 acattaggaa gaggacacac caagggtgat catcaatata accatccgat tttgagcagt
     1141 gttacccaga tcccgccaca tgagaagcca cggatgaaca acatcctgac atcagccacc
     1201 gagccctatg acctctcctt ctcccgctcg ttccagaact tggcccacct gcccccatcc
     1261 tacgagtctg cagtaaagac caaccccagc aagtattcat ctctgaagag gctaaccgac
     1321 aaggaggctg acgagtatta catgagacgg cggcacctgc ccgacctggc tgcccgcggc
     1381 accctccccc tcaatgtcat ccagatgtcc caacagaagc cgttgccaag ggaacgaccc
     1441 cgccggccca tccgggccat gtcccaggac agggtcctgt ccccggatcg gggcctgcca
     1501 gatgagttca gcatgcccta cgaccgcatc ctgtccgacg agcagctgct ctccacggag
     1561 cgcctgcact cccaggaccc gctgctgtcc ccggagcgga cggcctttcc cgagcagtcg
     1621 ctgtccaggg ccatctcgca cacggacgtc tttgtgtcca cacccgtgct ggaccgctac
     1681 cgcatgagca agatgcactc tcatcccagt gcctccaata actcatacgc caccctgggc
     1741 cagagccaga cggcagccaa gcgtcatgcc tttgcctcac gcagacacaa cacggtggag
     1801 cagctgcact acatcccggg ccaccacacc tgctacacag ccagcaagac cgaagtgacc
     1861 gtgtgaccgg cggggcaggg ccggggctgc tgggcgtggc agagcagagc gggggccggg
     1921 aggggccagg agcagagctt ctagccttgc cactctccct tcccttgtcc cctctgtagg
     1981 aagtgggggt gggccacctt tgcccaaaaa gccatacccc cggggacaca gccccgatgg
     2041 cctggtccaa tacacttaga cccaggacca agagcaatcg ctcttgctcc tccagaagaa
     2101 tcagtgggga gtgaggaggg ggctaggccc cattctcacc cccgaccacc ttcaccaact
     2161 ccctttccgt cccgcgcctc cttctcccca tccgggggac tcagctgcag gttctgtcag
     2221 cagagagacc cttgcttgac tgtggtctga agctgcctgg gtttgaaggg gccagcgggt
     2281 ccaatcagtg ggctgaccgg ataggctact cggtctcatt cattcatcta gaaccgcatc
     2341 acagaaatct cctagtgcct aaaaactgcc tgctcgctct ctcagagcca gggagctgct
     2401 gtgtccataa gcacaataat gattcttttc ttgcctgctg gaactctctg gtccccactg
     2461 agtgaccctt cctttgctga cccctgaggg cccaaccctg gccctgtgcc cctcccctca
     2521 actccaggac caggaggggt tcccttcctt cagctgcctc cccattggtg ggaactccac
     2581 ccccttccag ctgactgccc gcccataagg accctgggcc tgtcctttca gcgggctgtg
     2641 ctccttccct ggccctgagg atttcaccct tgagttttct ggggttttgg ctgtagcctt
     2701 cgcagagggg agtagcaatg gggtgctggc cctcccagac acccgatcat ctccgcactc
     2761 cctccaggcc tctagacctg accatgactg ccactcaggc tgccttctcc acccctgctc
     2821 tgctcccagg aggcacctgc ggtggccaga gagccagggt ggggagggcc actgtgatgt
     2881 gcggggtctc gggctcaaca ttcgcatcct gcagggctcc acctgttccc acatgcacct
     2941 ccggcaggac ctagacagaa gtttctagag agcagctttt cagcccccag acaaggagga
     3001 tgagaggtgg ttgtcctgca tcctctccgc tcatccttcc ttccccatct ctgtctacct
     3061 gctcagttca gagatcactc ctactgcctg tgtccccttc ccccacatcc tccctgcaac
     3121 tttattcctc ctagctgatc cttcagatcc gtgcctcctc tggatcaaag ggacaaagac
     3181 ctattagcaa aagcaaacaa aggtcctcca ggcgactggc ctaggggcta actgggcagg
     3241 tccccacagc atcatccctt tgtgcaggca ctggggtacc tggtagacca tggtcctcag
     3301 ctctgttggg ggaccgccac tgcccgccca cctcagcctc ttccccgcct ccagcctggg
     3361 ggttggcatg gtgtgacggc ctcctgggga ggtgacagtg aattcagcag catccgctcc
     3421 cccaagacca gagagcctgg tgggggaaag aaggggttcc ctcattctca gggccagggc
     3481 acccgctggg ttggggctgg gggaatcaac tccaggctat tgggtgaagg tgtgatccta
     3541 aaaacagtca gatccaacag cagtgccctt ataaatgggg ttttacctgc cctcagttct
     3601 gcactcatgg ccctttaaaa aggcgagtgt agaaggagaa tttattggtg tcagccctgg
     3661 agatttttaa tctaaccaag tccacaaacc acagagaaag caatggactg tgtcctttca
     3721 ctgatttcaa gagttccaaa gctctcatct ccttctcccc tctgcagggt gtgcctccca
     3781 acaggaacag gaaaccatca ccctggatct tagggggatg gaggctgggg gttgtgaaag
     3841 ccactgtcag accccacact ggggatgcat tcctggagtc gtgcggctgg aaggccaggg
     3901 actaccctct ctgctttcct cccaacagac acataaacct tcttaagggc tggtccccag
     3961 gggtttataa gagtttgttc cagaaggtga ggctaagagg gttggaaagg aagaagtgag
     4021 tctgaataga gcaggtggct cccagctggg cccctgagcc cagcaccttt gaatcgtcta
     4081 atctgtggcc atcccttgga aggcaggatg ctggtggtga ggggaaagga cctgagtggc
     4141 tgagaatgcc cttcccaggt gtctacatgc aggtatacac caaaccagaa agctgatccc
     4201 atctccagtg tcaaagcttc tcagcaccaa gttctccagc ccccagggtg acacttttcc
     4261 ccaggggtcc tccccaagcc ctgtctctga cagggtttct gtctctctca ggggttgttg
     4321 atgagttgat tccaagacat ttctcatccc agccttacca ctgtctggct gaaaggctct
     4381 gatgtcagtt gggttggaaa attctactgc aatgcttact tcttttcaag gatttcttct
     4441 gcttcacctt tgggtctaga agcaaggaat gaagggaggg agagagggag ggagggaggg
     4501 gaggagggaa gaaaaaagaa gtagagatag gtctacagac ttgctccaat tcagtcccac
     4561 atttcaaaat ccagaaaact atgtcatagc tgggacagag aggtatccca tttattcagc
     4621 tgtcccatcc atcttcatgg aacaagcaaa gccacatcaa taggcaagtt cacgtagcag
     4681 ataaaagagg cttctggggc tggaacctag atgccatgat ttctagccca accaggctgg
     4741 tggcctctac catacataga agtaccatcc acccttacag taaaagcctc cctcctgctc
     4801 acaaaggaag cctaaagccc aagatttccc tctccttgtt ttattcattt ttgcacatct
     4861 ctgttgctct aacagaaatg aactggaatc tgcacaggtt ctctcctgcc ctgaaagttc
     4921 tgcctggttt ccttggcctc tgatggcatt gaagctttca caatccctcc tgcatctcca
     4981 ccttccctgt cttgctccag gctcctggct ccatgccttc ctgtgtcaaa aaggctttgc
     5041 caagaattac ttcacctcct aaccaggctt ctgccctcag ggctccccca gtgtcttggg
     5101 agtgtcttgg gccacacgac tgcctcttag aaagttccaa ccttgccccc aattcaaatt
     5161 tctcctcccc tctttccact ctccctccca gaaactcctg atttccagaa aacctcagat
     5221 ttccaggcca ggtcactcat tccttcctct catctccctc ttcctccatc taccttcctc
     5281 cattcacctt cctccattcc taatttcttt tccctggtct tgctataatc tccagctcta
     5341 aaaatcagag ctctcaatga aaacaatgga agaataagac attctttcgg tcttctgttt
     5401 gcctcactgg tgtatccttc atctcctgcc cctgtgagtt gataccccag tgcacggagc
     5461 caagggcttt tcccctctga gctctgggag ggaagggaat ggagctctgg gtttgagatg
     5521 tcatggcctg tgatagtcag tttggttcct gccactagca agtcccctga agctcccaac
     5581 ccagcctgat gttagcccag aagctcctgc tctggccaaa gactcctatc cttgagggct
     5641 ctcagccact gctccaacac acttgccccc ttcctgcttg tgtatgtcac ttatcctcct
     5701 ttgtccacaa agacttgagg gcctcctgag tctccaagca tggaggaata tccatgccaa
     5761 catccctgcc atcaaactca atccattttc ttcagagata ccttgtctgt caccagcctc
     5821 caacttcata ttccttccac aggcaactgt gcacttgacc caaggtaaaa tgaaagggct
     5881 gccaatcact cggactccag aaggtgcctg ccctgagaag agctggcatg ttacctccca
     5941 catacatttc ctgtcatcct gtccgaatct gggaaatttt gctctggagt attttcaaga
     6001 aagcgcattg tgttttaatg aagtattttt cagggttcca atgttatttt ttataaatgc
     6061 agcattttaa tggcagattc aatatgaagg acatgtcttc ctgggctcta tatttgattt
     6121 tggaaggcag catactctag gagaaaaaaa gcatagggct gaggctctga agacacagct
     6181 tccagccctg gctttgtctc cgagggggag tcatgttccc cactcagtgc ctcagtttcc
     6241 ccatctgtaa aatgaggggc tttgactaga tgagctctga agtttcatcc agctcttaca
     6301 ctgtagggct ttcattccct gccagcacct gctctccccg ttcctcccca cctccactga
     6361 gctgcacaca tcccacaatg cctgccccac agcgatgtcc tcagatgtcc tggacagcca
     6421 ccgcactcct cactagagcc tggggtgggc ctgatgggct cggccaccca gggatgccct
     6481 cgtacctgaa gtttaagggc ctaaccattc aataggtcac caactgtgtg ccatggaagc
     6541 cctcttgtaa agacacacct aaaccatcct aagtgactgt ggaattctgg ggaattctga
     6601 gtttggagtt tccatttgga tacggtcctt atagctggag ggaggcggtt ccaatttcag
     6661 agagggagct ggctggagag aaaggtctgg aggttggccc ataagggcat gaagtttgta
     6721 cttgagggca gctgggaaat tcatttcaag ctgcagagga acgtgttcac aggctgttgt
     6781 gtggcaatga atgtcatgat aacccactct ggaatatgtg tcctgaagac caagtctgga
     6841 cactgaggct ccattccaac tggaggagga ggcatctcca tctgggctgc taggaagggg
     6901 cactcatccc atcctagtac ctttgtagcc cttcgtcatg acactaccgt cctcccggtg
     6961 aaggcttgtg aagcaagaat ggagagtcca agtttgtgat attcaaaccc atcttgtaaa
     7021 tcagcaaaca cattaacctt ccatcagtca gagaaataat gttgtggctg tgtgtttcct
     7081 taatgctctc cctcctgagg gaggagaaga ccctgctcaa ctttgctgcc caccctgcag
     7141 tgacccctga atgccacacc atgggaggac tcattcattg gctttgtagt ggcaaatatt
     7201 cctctagttc tataactcaa ctagacattt tgtagtaaag aattcttgaa attctctaat
     7261 aaaaagcaat tcttactgta atatttttag tttggggaca caatttccta aggggggatt
     7321 aatgaacatt tttatgcatt agcccaattt atgaattcca tgtttattat atggtagtac
     7381 tgatgaaaag tacctttcta tctgtatctt tgcagtttct tcgttactca tatgtaagcc
     7441 tcatggtaag cagtgctcta gtaactgctt ctctgtacaa atctcatcgt tctacttacc
     7501 tgtcaaagca cattctacat gtactgtaaa cagatacact ttagtaagat ttagtcttaa
     7561 ggatttttcc acttttgtca gtaacagata tttatggatt aaaaaataaa gccgtttcaa
     7621 cataa
//
