LOCUS       NM_001101404            2227 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens SH2 domain containing 7 (SH2D7), mRNA.
ACCESSION   NM_001101404 XM_001132402 XM_937092
VERSION     NM_001101404.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2227)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090260.13.
            
            On Sep 23, 2020 this sequence version replaced NM_001101404.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2142348,
                              SAMEA2148874 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000328828.6/ ENSP00000327846.5
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-200               AC090260.13        107328-107527       c
            201-290             AC090260.13        105887-105976       c
            291-456             AC090260.13        101994-102159       c
            457-669             AC090260.13        101492-101704       c
            670-1329            AC090260.13        98530-99189         c
            1330-2227           AC090260.13        95726-96623         c
FEATURES             Location/Qualifiers
     source          1..2227
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q25.1"
     gene            1..2227
                     /gene="SH2D7"
                     /note="SH2 domain containing 7"
                     /db_xref="GeneID:646892"
                     /db_xref="HGNC:HGNC:34549"
     exon            1..200
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1380
                     /gene="SH2D7"
                     /note="Putative SH2 domain-containing protein LOC646892"
                     /codon_start=1
                     /product="SH2 domain-containing protein 7"
                     /protein_id="NP_001094874.1"
                     /db_xref="CCDS:CCDS45315.1"
                     /db_xref="GeneID:646892"
                     /db_xref="HGNC:HGNC:34549"
                     /translation="MEDSLKQLSLGRDPEGAGDSQALAELQELALKWFMETQAPFILQ
                     NGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYILSYRGSDRCRHFVINQL
                     RNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPRPEDNDLYDAITRGLHQ
                     TIVDPENPPATAFLTVVPDKAASPRSSPKPQVSFLHAQKSLDVSPRNLSQEESMEAPI
                     RVSPLPEKSSSLLEESFGGPSDIIYADLRRMNQARLGLGTEGSGRHGPVPAGSQAYSP
                     GREAQRRLSDGEQNRPDGLGPVLSGVSPDQGPTESPTSWGCSDAMGSLGATWRQEFPK
                     LSQEAQPCSQGSSADIYEFIGTEGLLQEARDTPDQEGSTYEQIPACWGGPARAPHPGA
                     SPTYSPWVHGYKRISGTPELSEPGNTYEQIPATKSKETGRTHKPDKLRRLFFTYRKHK
                     F"
     exon            201..290
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
     exon            291..456
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
     exon            457..669
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
     exon            670..1329
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..2227
                     /gene="SH2D7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttccactc tggtgcctgc cagcatggag gacagcctaa agcagctcag cctggggaga
       61 gatcctgagg gggcagggga cagccaggcc ctggctgagc tccaggagct tgccctgaag
      121 tggttcatgg agacacaggc ccccttcatt ctgcagaacg gtgccctgcc tccctggttt
      181 catggattca tcacccgcaa gcagacggag cagctactca gggacaaagc tcttggttcc
      241 ttccttatcc gcctcagtga ccgagccact ggctacatct tgtcctacag gggcagtgat
      301 cgctgccgac attttgtcat caaccagctt cgaaaccggc gttacatcat ctcaggagac
      361 acccagagcc acagcaccct ggctgagctt gtgcaccatt accaggaggc acagctcgag
      421 cccttcaaag agatgctgac tgctgcctgc ccccggccag aggacaatga tctgtatgat
      481 gccatcaccc ggggcctcca ccagaccatc gtggacccag aaaacccacc tgccacggca
      541 ttcctcacag tggtccccga caaggccgcc agcccccgct cttctccaaa gccccaggtc
      601 tccttcctcc atgcacagaa aagcctggat gtgagtcccc ggaacctctc ccaggaggaa
      661 agcatggagg ctcccatcag agtgtctcca ctccctgaga agagttcctc cctcctggaa
      721 gagtcttttg gaggccccag tgacatcatc tatgcagacc tgaggaggat gaaccaggca
      781 cggctaggct tgggcacaga ggggtccggc aggcatgggc cagttccagc tggcagccag
      841 gcctactccc caggcaggga ggcccaaagg agactctcag atggagaaca gaacaggcct
      901 gatggcctgg ggcctgtcct ttctggggtg agcccagacc agggtcccac agagtctccc
      961 acttcctggg gatgttctga tgccatggga tccctggggg ctacctggag gcaggagttt
     1021 ccaaagctga gccaagaggc tcagccctgc tcccagggca gctctgcaga tatctatgag
     1081 ttcatcggga cagaaggcct cctgcaagag gccagggaca caccagacca agaaggcagc
     1141 acctatgagc agatcccagc ttgctggggt ggcccagcca gggccccaca tcctggggcc
     1201 agtcccacat atagcccatg ggtccatggc tacaagagga tctcagggac cccagagctc
     1261 tcagagcctg ggaacaccta tgaacagatc ccagcaacca agagcaagga gactggacgg
     1321 acacacaagc ctgacaagct tcggaggctc ttcttcacgt acaggaagca caaattctga
     1381 gggcctggca tccggcagcc caccagtggg tttcctggta cccaggccat gccaggggtt
     1441 atcgcaaagg cctcagctca cttgaaggca ccctttggat cttgagactc atccagcctg
     1501 ctacagaact aggctccgag acagccgagg tgcctgcctg agagcaggtg gaagaggacc
     1561 ttgcaggtgc ctgcagctcc tggctatgtc ctgctttcct tgtgcctccc atccatgcac
     1621 aggagggact ggagaggaat gagattggcc aaaggcaggg gtcaccaccc ccatttccca
     1681 gataagcatg ctgaggccca ggcagactga ctgaacctgc ctcccactac tgagcactta
     1741 ccgaatgtgt ggcaggctgt gtgctagcac agacaccttt ctaactggcc aagtgacatc
     1801 atgcaattgc taccgagaac aaaaccagtt cccctccttg cggccccatc agcgaaaagg
     1861 aggggagggc cagaagccac atcctctgct tcaggcctct tcgctccagc tgtaccctca
     1921 ggtcaggctg gctcttcctg gaactctgtc cctcaggaaa cttcctgttt tgtgtgtcac
     1981 ttcccttcct atccacatgt ccccttctct ataagggtgg acagctggct tgctacccca
     2041 ctcccaacaa cccccaggcc tgggatgcag aaaacaggac tgatcatctc cagagagaac
     2101 accatacgtg cccctcctcc ctgccctgac cctgggcaga gcgggctcag gttgcatttg
     2161 tgggaaatct actcttagtg accacttggc tatgcagctt ttcctgaaat ataggcctgt
     2221 aagagtc
//
