LOCUS       NM_001007467            4031 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens SFI1 centrin binding protein (SFI1), transcript
            variant 1, mRNA.
ACCESSION   NM_001007467
VERSION     NM_001007467.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4031)
  AUTHORS   Arslanhan,M.D., Cengiz-Emek,S., Odabasi,E., Steib,E., Hamel,V.,
            Guichard,P. and Firat-Karalar,E.N.
  TITLE     CCDC15 localizes to the centriole inner scaffold and controls
            centriole length and integrity
  JOURNAL   J Cell Biol 222 (12) (2023)
   PUBMED   37934472
REFERENCE   2  (bases 1 to 4031)
  AUTHORS   Laporte,M.H., Bouhlel,I.B., Bertiaux,E., Morrison,C.G., Giroud,A.,
            Borgers,S., Azimzadeh,J., Bornens,M., Guichard,P., Paoletti,A. and
            Hamel,V.
  TITLE     Human SFI1 and Centrin form a complex critical for centriole
            architecture and ciliogenesis
  JOURNAL   EMBO J 41 (21), e112107 (2022)
   PUBMED   36125182
  REMARK    GeneRIF: Human SFI1 and Centrin form a complex critical for
            centriole architecture and ciliogenesis.
REFERENCE   3  (bases 1 to 4031)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   4  (bases 1 to 4031)
  AUTHORS   Karlsson,L., Barbaro,M., Ewing,E., Gomez-Cabrero,D. and Lajic,S.
  TITLE     Genome-wide investigation of DNA methylation in congenital adrenal
            hyperplasia
  JOURNAL   J Steroid Biochem Mol Biol 201, 105699 (2020)
   PUBMED   32428554
  REMARK    GeneRIF: Genome-wide investigation of DNA methylation in congenital
            adrenal hyperplasia.
REFERENCE   5  (bases 1 to 4031)
  AUTHORS   Kodani,A., Moyer,T., Chen,A., Holland,A., Walsh,C.A. and
            Reiter,J.F.
  TITLE     SFI1 promotes centriole duplication by recruiting USP9X to
            stabilize the microcephaly protein STIL
  JOURNAL   J Cell Biol 218 (7), 2185-2197 (2019)
   PUBMED   31197030
  REMARK    GeneRIF: these results demonstrate that SFI1 is a centrosomal
            protein that localizes USP9X to the centrosome to stabilize STIL
            and promote centriole duplication. We propose that the USP9X
            protection of STIL to facilitate centriole duplication underlies
            roles of both proteins in human neurodevelopment.
REFERENCE   6  (bases 1 to 4031)
  AUTHORS   Kilmartin,J.V.
  TITLE     Sfi1p has conserved centrin-binding sites and an essential function
            in budding yeast spindle pole body duplication
  JOURNAL   J Cell Biol 162 (7), 1211-1221 (2003)
   PUBMED   14504268
REFERENCE   7  (bases 1 to 4031)
  AUTHORS   Casenghi,M., Meraldi,P., Weinhart,U., Duncan,P.I., Korner,R. and
            Nigg,E.A.
  TITLE     Polo-like kinase 1 regulates Nlp, a centrosome protein involved in
            microtubule nucleation
  JOURNAL   Dev Cell 5 (1), 113-125 (2003)
   PUBMED   12852856
REFERENCE   8  (bases 1 to 4031)
  AUTHORS   Takahashi,M., Yamagiwa,A., Nishimura,T., Mukai,H. and Ono,Y.
  TITLE     Centrosomal proteins CG-NAP and kendrin provide microtubule
            nucleation sites by anchoring gamma-tubulin ring complex
  JOURNAL   Mol Biol Cell 13 (9), 3235-3245 (2002)
   PUBMED   12221128
REFERENCE   9  (bases 1 to 4031)
  AUTHORS   Mayor,T., Stierhof,Y.D., Tanaka,K., Fry,A.M. and Nigg,E.A.
  TITLE     The centrosomal protein C-Nap1 is required for cell cycle-regulated
            centrosome cohesion
  JOURNAL   J Cell Biol 151 (4), 837-846 (2000)
   PUBMED   11076968
REFERENCE   10 (bases 1 to 4031)
  AUTHORS   Golsteyn,R.M., Mundt,K.E., Fry,A.M. and Nigg,E.A.
  TITLE     Cell cycle regulation of the activity and subcellular localization
            of Plk1, a human protein kinase implicated in mitotic spindle
            function
  JOURNAL   J Cell Biol 129 (6), 1617-1628 (1995)
   PUBMED   7790358
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC369842.1, AK292408.1, AL708501.1, BC021576.1, AI141022.1 and
            AL096768.7.
            
            On May 17, 2019 this sequence version replaced NM_001007467.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK292408.1, SRR7346977.1509962.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000400288.7/ ENSP00000383145.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                DC369842.1         381-407
            28-1095             AK292408.1         1-1068
            1096-1096           AL708501.1         43-43
            1097-3056           AK292408.1         1070-3029
            3057-3991           BC021576.1         1021-1955
            3992-3994           AI141022.1         6-8                 c
            3995-4031           AL096768.7         16221-16257
FEATURES             Location/Qualifiers
     source          1..4031
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.2"
     gene            1..4031
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /note="SFI1 centrin binding protein"
                     /db_xref="GeneID:9814"
                     /db_xref="HGNC:HGNC:29064"
                     /db_xref="MIM:612765"
     exon            1..102
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            103..224
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..3861
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /note="isoform a is encoded by transcript variant 1;
                     homolog of yeast Sfi1; protein SFI1 homolog; protein
                     phosphatase 1, regulatory subunit 139; Sfi1 homolog,
                     spindle assembly associated"
                     /codon_start=1
                     /product="protein SFI1 homolog isoform a"
                     /protein_id="NP_001007468.1"
                     /db_xref="CCDS:CCDS43004.1"
                     /db_xref="GeneID:9814"
                     /db_xref="HGNC:HGNC:29064"
                     /db_xref="MIM:612765"
                     /translation="MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSA
                     KTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRM
                     TFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQT
                     WKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRI
                     ILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVS
                     AVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRE
                     SLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRAL
                     KDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRI
                     ALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSA
                     RATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAAR
                     HQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQ
                     WRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQ
                     LLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDC
                     AIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHH
                     LQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKV
                     WATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQ
                     AAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTL
                     ETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEH
                     GLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLS
                     SFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGS
                     LDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQK
                     ELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC"
     exon            225..398
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            399..470
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            471..581
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            582..676
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            677..794
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            795..897
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1054
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1216
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1287
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1380
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1478
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1545
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1676
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1758
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1759..1937
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2013
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2109
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2110..2186
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2289
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2386
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2387..2547
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..2622
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2623..2697
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2874
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            2875..3128
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3129..3200
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3201..3432
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3433..3565
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3566..3644
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3645..3756
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     exon            3757..4031
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3972..3977
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /note="hexamer: ATTAAA"
     regulatory      3976..3981
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /note="hexamer: AATGAA"
     polyA_site      3991
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
                     /note="major polyA site"
     polyA_site      3994
                     /gene="SFI1"
                     /gene_synonym="hSfi1p; PISD; PPP1R139"
ORIGIN      
        1 gaggcgggcg tggaccgcgc gggagttaag aagcaggtcc cggatcgccg tataccgccg
       61 ggttttctcc caacgtcagg cccgatggct cggcttcccc agttagaagg ggaagataaa
      121 agactttgat tcatgaagaa tctgctcact gagaagtgta tatcaagcca caatttccat
      181 caaaaagtga ttaagcagag aatggagaag aaggttgatt ccaggtattt taaggatggt
      241 gcagttaaga aaccttattc tgcaaagaca ctgtccaaca agaagtcttc tgcatccttt
      301 gggatccgga gggagttacc tagtaccagt catctagtgc agtatcgtgg cacacatact
      361 tgtacccgac agggccggtt aagagaactg cgcatcagat gcgtggccag aaagttctta
      421 tatttatgga ttcgaatgac ttttggaaga gtatttccct ctaaagccag attttactat
      481 gagcagcgat tactacggaa ggtcttcgaa gaatggaaag aggagtggtg ggttttccag
      541 cacgagtgga aactctgtgt tcgagctgac tgtcactaca ggtattacct gtacaacctg
      601 atgttccaga cgtggaagac ctatgtgcgt cagcagcagg agatgaggaa caagtacatt
      661 agagccgagg ttcatgatgc aaagcaaaag atgcgacagg cctggaagtc ctggttgatc
      721 tacgtggttg ttcgtaggac caaacttcag atgcagacta cagctctgga gtttaggcaa
      781 cggattatct tacgggtgtg gtggagcacg tggaggcagc gactaggaca ggtccgtgtg
      841 agccgtgccc tccatgcctc tgctttgaag cacagggccc tgagcctcca ggtgcaggct
      901 tggtcacagt ggcgggaaca gctcctgtat gtccagaagg agaaacaaaa ggttgtctct
      961 gcagtgaaac atcatcagca ctggcaaaaa cggagatttc taaaggcctg gcttgaatac
     1021 ctgcaagtcc gcagagtgaa gagacagcag aatgagatgg ctgagcgatt ccatcatgtc
     1081 actgtgctcc agatatactt ctgtgactgg cagcaggcct gggagcggag ggagagcttg
     1141 tacgctcacc atgcccaggt ggagaaactg gccaggaaga tggccctgcg gcgcgccttt
     1201 actcactgga aacactacat gctgctgtgt gcagaagaag ctgcccagtt tgagatggca
     1261 gaagagcacc acaggcacag ccagctgtat ttttgcttta gagccctaaa agacaatgtg
     1321 acccacgctc atctccagca aataagaagg aatcttgctc accagcagca tggtgtcacg
     1381 ctgctgcaca ggttctggaa cctctggcgg tctcagattg agcagaaaaa ggaaagagag
     1441 ctgctcccct tactgcatgc tgcctgggac cactacagaa tagcactgct gtgcaaatgt
     1501 atcgaattgt ggctacagta tactcagaag aggcggtaca agcagctgct acaggccaga
     1561 gcggatggtc atttccagca gagagccctg cctgctgcct tccacacatg gaacagactc
     1621 tggcgatggc gccaccagga aaatgtcctc agtgcaagag caacacgttt ccacagggag
     1681 acattagaga agcaagtatt ttctctctgg aggcagaaga tgtttcagca tcgagaaaac
     1741 cgcctggcag agagaatggc catccttcac gcagagcgac agcttctgta taggtcttgg
     1801 ttcatgtggc accagcaggc agcagcacgt caccaggagc aggagtggca aacagtggcc
     1861 tgtgcccacc accgccacgg gcggctcaag aaagctttct gcctctggag ggaaagtgcc
     1921 caagggctca gaacagagag gacgggcagg gtgcgggcag cagaattcca catggcccag
     1981 ctcctgcgtt gggcctggag ccagtggagg gagtgcctgg ccctgcgggg agcggagcgg
     2041 cagaagctga tgcgagcaga cctgcaccac cagcacagcg tgctgcacag ggcgctgcag
     2101 gcatgggtga cttaccaggg cagggtgcga agcatcctcc gggaggtggc agccagggag
     2161 agccagcaca acaggcagct gctgcgcggg gcattacgtc gctggaaaga gaacaccatg
     2221 gcccgagtgg atgaagccaa aaaaaccttt caagcaagta ctcattacag aaggaccata
     2281 tgttccaagg tcctggtcca gtggcgggaa gctgtgtcag tgcagatgta ttaccgacag
     2341 caggaggact gtgccatctg ggaggcccag aaggtgctgg acaggggctg tctgcggacc
     2401 tggtttcagc gctggtggga ctgcagccgg aggtcagccc agcagagact gcagctggag
     2461 agggcagtgc aacaccacca ccggcagctg ctgctggagg ggctggcccg gtggaagacg
     2521 caccatctgc agtgtgtcag gaagaggctc ctgcacaggc agagcaccca actgctggca
     2581 cagagactca gccggacctg cttccgccag tggagacaac agctggcagc caggaggcag
     2641 gagcagcggg cgacagtgcg ggccctgtgg ttctgggcct tctcgctgca ggcaaaggtg
     2701 tgggccacgt ggctggcctt tgtactggaa aggaggagaa agaaggcgcg gctgcagtgg
     2761 gcgctccagg cctaccaggg gcagctcctc caggagggtg ccacgcggct cctgcgcttt
     2821 gcagccagca tgaaggcctc ccggcagcag ctgcaggccc agcagcaggt ccaggcggct
     2881 cacagtctcc atcgtgccgt ccgccgctgt gccacgctct ggaaacagaa agtgctgggc
     2941 cggggcggga agcctcagcc cctggcagcc atcgcaccca gcaggaaagt gacgtttgag
     3001 ggtccccttc tcaaccgcat tgctgctggg gctggggatg gcacccttga gaccaagagg
     3061 ccacaggctt ctcggcctct gggagctctg ggccgcctgg ctgctgagga gccccacgcc
     3121 ctggagctca acactgccca ctcagcgagg aagcagccgc gacgcccaca cttcctgttg
     3181 gagcctgcgc agagccagag gcctcagaag ccacaggaac atggcctagg catggctcag
     3241 ccagcagccc cctccctgac gcggcccttc ctggcagagg ccccgacagc actggtccca
     3301 cacagccccc tgcctggggc cctgtcaagc gcccctggcc cgaagcagcc cccgacggca
     3361 agcacaggcc cggagctgct gctgctgcct ctttcctcct tcatgccctg cggggcggct
     3421 gcaccagcca gggtgtcagc acagcgggct actcctaggg ataagccccc ggtcccctca
     3481 tccctggcca gtgtccctga cccccatcta ctccttcctg gggacttctc agccaccagg
     3541 gctgggcctg gactttcaac tgcaggcagc ctggaccttg aggctgaact tgaggagatc
     3601 cagcagcaac tactgcacta ccagaccacc aagcagaacc tctggtcctg tcggcggcaa
     3661 gcgagcagcc tgcgcaggtg gctggagctg aacagagagg agccggggcc tgaggaccag
     3721 gaagtagagc agcaggtgca gaaagagctg gaacaggtgg aaatgcagat ccagctgctg
     3781 gcagaggagc tccaggctca gcgccagccc attggcgcct gcgttgcccg catccaggcc
     3841 ctgcggcagg ccctgtgcta gcgtgttcgc accaggaacg caggtgctgg gctgtcgggg
     3901 aggcctcagg ccacctccag gaacagaaca cagttttaag tttgattttt tttatttcaa
     3961 aatgctttgc aattaaatga attactgttc agaagtctcc cacttttcat acaaaaatac
     4021 tgtgctactg a
//
