LOCUS       NM_001354473            4612 bp    mRNA    linear   PRI 31-OCT-2024
DEFINITION  Homo sapiens serine rich and transmembrane domain containing 2
            (SERTM2), mRNA.
ACCESSION   NM_001354473 NR_033974
VERSION     NM_001354473.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4612)
  AUTHORS   Pereira,I.T., Gomes-Junior,R., Hansel-Frose,A., Franca,R.S.V.,
            Liu,M., Soliman,H.A.N., Chan,S.S.K., Dudley,S.C. Jr., Kyba,M. and
            Dallagiovanna,B.
  TITLE     Cardiac Development Long Non-Coding RNA (CARDEL) Is Activated
            during Human Heart Development and Contributes to Cardiac
            Specification and Homeostasis
  JOURNAL   Cells 13 (12), 1050 (2024)
   PUBMED   38920678
  REMARK    GeneRIF: Cardiac Development Long Non-Coding RNA (CARDEL) Is
            Activated during Human Heart Development and Contributes to Cardiac
            Specification and Homeostasis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4612)
  AUTHORS   Chuang,T.D. and Khorram,O.
  TITLE     Expression Profiling of lncRNAs, miRNAs, and mRNAs and Their
            Differential Expression in Leiomyoma Using Next-Generation RNA
            Sequencing
  JOURNAL   Reprod Sci 25 (2), 246-255 (2018)
   PUBMED   28587571
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035067.2, DR005240.1, BX537697.1, BY994992.1 and AA429445.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001354473.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX537697.1, SRR5189667.210444.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000569275.2/ ENSP00000490917.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AL035067.2         93347-93363
            18-28               DR005240.1         1-11
            29-1109             BX537697.1         1-1081
            1110-1110           AL035067.2         100599-100599
            1111-4051           BX537697.1         1083-4023
            4052-4052           BY994992.1         713-713
            4053-4438           BX537697.1         4025-4410
            4439-4473           AA429445.1         142-176             c
            4474-4612           BX537697.1         4446-4584
FEATURES             Location/Qualifiers
     source          1..4612
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq23"
     gene            1..4612
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /note="serine rich and transmembrane domain containing 2"
                     /db_xref="GeneID:401613"
                     /db_xref="HGNC:HGNC:48576"
     exon            1..190
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /inference="alignment:Splign:2.1.0"
     exon            191..287
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /inference="alignment:Splign:2.1.0"
     exon            288..4612
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /inference="alignment:Splign:2.1.0"
     CDS             1071..1343
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /note="long intergenic non-protein coding RNA 890; CARdiac
                     DEvelopment Long non-coding RNA"
                     /codon_start=1
                     /product="serine-rich and transmembrane domain-containing
                     2"
                     /protein_id="NP_001341402.1"
                     /db_xref="CCDS:CCDS94655.1"
                     /db_xref="GeneID:401613"
                     /db_xref="HGNC:HGNC:48576"
                     /translation="MMEAHFKYHGNLTGRAHFPTLATEVDTSSDKYSNLYMYVGLFLS
                     LLAILLILLFTMLLRLKHVISPINSDSTESVPQFTDVEMQSRIPTP"
     regulatory      2135..2140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /note="hexamer: AATAAA"
     polyA_site      2152
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /note="major polyA site"
     regulatory      4590..4595
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
                     /note="hexamer: AATAAT"
     polyA_site      4612
                     /gene="SERTM2"
                     /gene_synonym="CARDEL; DKFZp686D0853; LINC00890"
ORIGIN      
        1 agagcagagc tgaatcacta cctttcccgc atactctaaa ctgttgcctg cgaaagagga
       61 actggggact tagactaatt caggctgctt tcattcaaat gttccagagg gcacacacac
      121 atccaaacag acttctcttt gcttttcaga gcttataagg agcaggcatc tgaagctgca
      181 ctctgaagct ctattccaga gatgttcctg aacaagttac ctgttggtga aagcttcaaa
      241 agggatactt aagtgaccaa tcctattcat actgtgggcc aggagaggaa aatcaatatc
      301 tgttggagaa tctgaagagc caaatctcct gagcctaggc ctactgctgt cagcatctct
      361 gagacctctc tcacctgaga attaccaggt ctgacaacac tttccctcca gcctacagtg
      421 agggatgtca acaaagctac agaaaactca cattctgtag acttacaagc tgtgcagctg
      481 ggcaggaacc ttacaatctc catccttagg gaaggttcag aaatacagat aaacggggtg
      541 aaaactcaga taagctgagc ctgatatata caaaagcctt cagatagtct cctcgcagaa
      601 gagcccaatt aagtccacat aattagtcca cacatctaga ttaggtatag gcaaaacgag
      661 ccttttctcc atctacgaaa acagagcaaa acactgatat aatactctaa aagattcttg
      721 ttctaataac agtattataa agcagtttca cccatattta ttttaatcag tataaaagta
      781 ggagtgtgga aaataaaaca ttacttgtat ttttaaaaat tgattaagaa gctctgataa
      841 aacctattgg aggggcgatt gctgtgctga aggatagaga gggtgttgca attgtcaaat
      901 agcatcacca ttttctgctt gtgtgctatt gccttagctc tgagagtgat tggtttttac
      961 cagattgtta gaacacgtcc aatagattta gagacagtct aagtgactgt gaaatgcctc
     1021 aagggcagta gaaatcaaat agaaacacat actaactcaa gtcttgagtg atgatggagg
     1081 cgcattttaa ataccatgga aatctcactg ggcgtgccca ttttcccact ctggcaacag
     1141 aggttgatac ctcttcagac aagtattcca acctgtacat gtatgtgggc ttattcctga
     1201 gcctcctggc cattctcctc atcctgctct tcacaatgct ccttcggctc aaacatgtca
     1261 tctcgcccat caactctgac agcacagaaa gtgttcctca gttcacagat gtagagatgc
     1321 agagtcgaat ccccactccc taaagccagg atgaaggtga gctttagtgg atctgggtaa
     1381 acccttatat atggatgtcc aggagagctt gctttcttgc atgaagcttc ccatgtaggg
     1441 aatccacaag ttgttcattt aacagcaagc tgttcatgtt ttctttgtgt tattcttcat
     1501 ctttactctg cttgtgggct atctaaaacg tttaagactc actctgaaag gaatatagga
     1561 aaagacagct ggttgggagg gctggtttcc atagtaacca aacagtgcct gggccttgca
     1621 caaacctcag accacagaaa ttcatgcgca gtggttgtaa gaagcacagg gtccctggaa
     1681 gctccaaaaa caaacaaaga agatttgctt ttgaaagggc tgatccttca aagaggatat
     1741 cccaagaaaa ggacaagttc taatttagtg ttttgatcct agagaatcac ctctatacaa
     1801 agttaaatta tgtcagaagt taatggaaga gaagcccttt ccctaaacag cagtgatttg
     1861 atcatcttag gcaatccggt ttgtttcaaa tgaaagaaga gatttaaaga aactgtttca
     1921 gtttagagag caagttttca gaaagaagtt tctagtaaac aaactcatct agagagagaa
     1981 aaatgtgcat attatatcca tattaattct attcatgcag cttctttgtc tttttctctc
     2041 tccctctcac actctaggat agagttgcac acaaatatga gctttgttta aaaggtgcct
     2101 ttgcaaacaa gactcaactg tactttagag cagaaataaa atgatgttgg tattctgttg
     2161 ttgaatatgg ctttggacaa aacattcaag ccttctgagt cccagggttt ttgtgctgaa
     2221 aaatgattag agagctattt agtcatcact atactcttta gatctgagca taaaaaaaag
     2281 agagagagac aaaggaggaa aggactaaac aacatcctcc aacaaatcct tattgagatc
     2341 aatgtcctca aatgtcacat ttgtatttcc cagaaaatgt tcctcccttc ctgatccctg
     2401 ccaaaagatg aagtgtttca cttattacct ataagagaat tatattttga aaaattccat
     2461 tctcataagt agccctagta tgccagtagt gtggagagaa tttaattttt aaaactaact
     2521 tttcaaaggg aaaccaaagg agatgagtac catttacaaa tcagaattta aaaaactggt
     2581 catattcttg ccaccaaagg acgagtacac ctgtgttaaa ttttacttgc taaaacaaaa
     2641 aataagttat cttttgtacc taaagggggg tcatcaaatt tcacagagta ctctctcagg
     2701 aactgtaatg atggtaagag agaaatcaaa tagatgttag attaatgcca cctccaccag
     2761 aaatgtagct ctttgtagtc tgtaaccaat ttagattggc cctttttctc tgatctaaat
     2821 ctagattggt agtgaaattc ccaagtgctt tccactttta tacacagtca tttgtcaatg
     2881 ctcctctctc caaggggctg caagtgtgaa atccctacat gcagagctaa acttagcagt
     2941 aagactgact ctgccacacc tgttacaact gtgcactgtc agagatggga gctgcactct
     3001 gcatcattca aaacaaatta gcagataggc taagacttgg atagggcata tatttttcaa
     3061 aactcaaagt gactcacatt attacacctt gatggtctaa gttgtgtgtt tattcaacac
     3121 ccagattcag tggacccttt aaaatttgag ctttggcagc caaacatgga cttcctcaag
     3181 actggcaaca ccccccctcc agaacttctt aagaacacac atcttccctc attccaggct
     3241 ctcacttttg tgcccacagt atttgaatgc actttacatt tgagaagtca gtggctggct
     3301 aaatgaagga actgattata ctttcaacag cagtgaatag caagatacaa aataccttgt
     3361 tgctgaatct aatagagata cagactgaaa atctattctc tgcccatctg accttcccaa
     3421 cccaaatttc aggagaataa aactgctttt taagcactga cttggatgaa gatttctaat
     3481 ttatgattag gttactcaca tggaaaacta tcaacctctt tcatcacaac taccccatgg
     3541 ggatccagct cgtcactgag cattaaccaa agcacacagc acagattaca ccaaaatagc
     3601 agcataacac cccccaccca atttccagtg acaatataaa tggaaatgct tttaagcaga
     3661 tgtgtcatta taatgactca catggtattt aatctttagg aaaataaact gaatgttttt
     3721 attgtagcaa acttactgta aagaaaagaa tttttacatt atatttattc cccaatgtat
     3781 taacatatat tactgctcaa aaaggcagcc agagtaacca gacggcacaa tttgaattta
     3841 tccttctatt cgaaatgctg acttggattg ccttccccca cccccactcc ctccaaaatt
     3901 gcacattagc cagtatataa acaggtaggt tatttatata tatgtgtact ctgttttaag
     3961 atgaaaagaa caattcttca ctttttatta gctgaaccat atgaaattgc catttgatag
     4021 gccaaaaaat gctcaaatat caccaacttc ataaaattca acctaataca aagactcacc
     4081 acattaattc tgtaaatagt aaattctcct aatatgttta aaaagaatcc aattttttaa
     4141 aatatatttt gcatatattt cagaatcatg ggttgtacaa aatgaagtat attgtaaaag
     4201 gcttatgtat tatgtattat gtattaagta ggaaatatta aggttaatca agtaaagatg
     4261 aattcatcca gcctaacctt tccatccatg ccaaatctga agctttggac tcataactga
     4321 gtttgactgc tgcagatccc accatactta ctaagtaggt ataagggatc cattttaata
     4381 catttcaatg gttatattta gtaatacatt ttattcactt gcatttgtac aaaagaactt
     4441 ttttttaaca aaatgaagaa ttgtgtggaa taaaaaattg agtttctttt gtttgaaatt
     4501 attaatgttt gaaatagatt catattgtat aaaaatggaa atatatttgc attaatattt
     4561 agcatgtcat ttttgatccc tggacaataa ataatgactg gtttgatgat aa
//
