LOCUS       NM_001010897             802 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens stress associated endoplasmic reticulum protein family
            member 2 (SERP2), transcript variant 1, mRNA.
ACCESSION   NM_001010897 XM_370724
VERSION     NM_001010897.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 802)
  AUTHORS   Zheng,J.S., Arnett,D.K., Lee,Y.C., Shen,J., Parnell,L.D.,
            Smith,C.E., Richardson,K., Li,D., Borecki,I.B., Ordovas,J.M. and
            Lai,C.Q.
  TITLE     Genome-wide contribution of genotype by environment interaction to
            variation of diabetes-related traits
  JOURNAL   PLoS One 8 (10), e77442 (2013)
   PUBMED   24204828
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 802)
  AUTHORS   Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
            Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
            Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
            Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
            Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
            Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
            Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
            Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
            Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
            French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
            Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
            Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
            Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
            Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
            Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
            McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
            Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
            Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
            Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
            Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
            Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
            Bentley,D.R., Rogers,J. and Ross,M.T.
  TITLE     The DNA sequence and analysis of human chromosome 13
  JOURNAL   Nature 428 (6982), 522-528 (2004)
   PUBMED   15057823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL138960.16 and BC029067.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001010897.2.
            
            Transcript Variant: This variant (1) is the longer protein coding
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC029067.1, BM925772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000379179.8/ ENSP00000368477.3
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AL138960.16        82234-82251
            19-668              BC029067.1         1-650
            669-669             AL138960.16        105991-105991
            670-802             BC029067.1         652-784
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.11"
     gene            1..802
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /note="stress associated endoplasmic reticulum protein
                     family member 2"
                     /db_xref="GeneID:387923"
                     /db_xref="HGNC:HGNC:20607"
     exon            1..286
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..400
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /note="ribosome-associated membrane protein RAMP4-2"
                     /codon_start=1
                     /product="stress-associated endoplasmic reticulum protein
                     2"
                     /protein_id="NP_001010897.1"
                     /db_xref="CCDS:CCDS31965.1"
                     /db_xref="GeneID:387923"
                     /db_xref="HGNC:HGNC:20607"
                     /translation="MVAKQRIRMANEKHSKNITQRGNVAKTLRPQEEKYPVGPWLLAL
                     FVFVVCGSAIFQIIQSIRMGM"
     exon            287..359
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /inference="alignment:Splign:2.1.0"
     exon            360..802
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      779..784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /note="hexamer: AATAAA"
     polyA_site      802
                     /gene="SERP2"
                     /gene_synonym="bA269C23.1; C13orf21"
                     /note="major polyA site"
ORIGIN      
        1 acttccgtcc gggctgcggc ctctctctgg agtcggctag ccggggctcg gggagcgggg
       61 tgcgcagggc tcggggccac gccttgccac ctgcagcgcc cgggtgggcc gcgggggcct
      121 cggcgggacg cgctcggccc tgtcgcagga gctaacgcag ggggaatcct tgcaggtggg
      181 agcatttcag agcgcacaag ccatggtggc caaacagcgg atccggatgg ctaacgagaa
      241 gcacagcaaa aacatcaccc agagggggaa cgtagccaaa accctgaggc cgcaagagga
      301 gaaatatcct gtgggaccat ggctgttggc actgtttgtt tttgttgtct gtggctcagc
      361 tatctttcag atcattcaga gcataaggat gggcatgtga gaaagccagg gatttgacac
      421 cacctccctc ccactggagg cgggaggaca acggaagcgg tcagccagtt tctgcgggaa
      481 acaagcaggc cacacggaat agaaaaaaac gctcccccac ttgttccctg atcacttcat
      541 cgtggatgtc agaccaaatt gccttctcac aggacatctt ggtgcatccg cgttctcaag
      601 cggaaaggac attttgcttt tctgttggca ggattagtag ccacgcgggt cgtccgcagc
      661 agtgctgttt ttttggtttt tcccttggtt tcactaatgc gtgcatgtgg ccctctgaac
      721 gatcactggt ttactttcta tggatacaat ctctcctcca ttgagaattg attttacaaa
      781 taaatgtctt cgttcaacct ta
//
