LOCUS       NM_003262               6526 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens SEC62 homolog, preprotein translocation factor
            (SEC62), mRNA.
ACCESSION   NM_003262
VERSION     NM_003262.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6526)
  AUTHORS   Kliche,J., Garvanska,D.H., Simonetti,L., Badgujar,D.,
            Dobritzsch,D., Nilsson,J., Davey,N.E. and Ivarsson,Y.
  TITLE     Large-scale phosphomimetic screening identifies phospho-modulated
            motif-based protein interactions
  JOURNAL   Mol Syst Biol 19 (7), e11164 (2023)
   PUBMED   37219487
REFERENCE   2  (bases 1 to 6526)
  AUTHORS   Radosa,J.C., Kasoha,M., Doerk,M., Cullmann,A., Kaya,A.C.,
            Linxweiler,M., Radosa,M.P., Takacs,Z., Tirincsi,A., Lang,S.,
            Jung,M., Puppe,J., Linxweiler,B., Wagner,M., Bohle,R.M.,
            Solomayer,E.F. and Zimmermann,J.S.M.
  TITLE     The 3q Oncogene SEC62 Predicts Response to Neoadjuvant Chemotherapy
            and Regulates Tumor Cell Migration in Triple Negative Breast Cancer
  JOURNAL   Int J Mol Sci 24 (11), 9576 (2023)
   PUBMED   37298528
  REMARK    GeneRIF: The 3q Oncogene SEC62 Predicts Response to Neoadjuvant
            Chemotherapy and Regulates Tumor Cell Migration in Triple Negative
            Breast Cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6526)
  AUTHORS   Mo,Z., Li,R., Cao,C., Li,Y., Zheng,S., Wu,R., Xue,J., Hu,J.,
            Meng,H., Zhai,H., Huang,W., Zheng,F. and Zhou,B.
  TITLE     Splicing factor SNRPA associated with microvascular invasion
            promotes hepatocellular carcinoma metastasis through activating
            NOTCH1/Snail pathway and is mediated by circSEC62/miR-625-5p axis
  JOURNAL   Environ Toxicol 38 (5), 1022-1037 (2023)
   PUBMED   36715182
  REMARK    GeneRIF: Splicing factor SNRPA associated with microvascular
            invasion promotes hepatocellular carcinoma metastasis through
            activating NOTCH1/Snail pathway and is mediated by
            circSEC62/miR-625-5p axis.
REFERENCE   4  (bases 1 to 6526)
  AUTHORS   Su,S., Shi,Y.T., Chu,Y., Jiang,M.Z., Wu,N., Xu,B., Zhou,H.,
            Lin,J.C., Jin,Y.R., Li,X.F. and Liang,J.
  TITLE     Sec62 promotes gastric cancer metastasis through mediating
            UPR-induced autophagy activation
  JOURNAL   Cell Mol Life Sci 79 (2), 133 (2022)
   PUBMED   35165763
  REMARK    GeneRIF: Sec62 promotes gastric cancer metastasis through mediating
            UPR-induced autophagy activation.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6526)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 6526)
  AUTHORS   Lim,J., Hao,T., Shaw,C., Patel,A.J., Szabo,G., Rual,J.F.,
            Fisk,C.J., Li,N., Smolyar,A., Hill,D.E., Barabasi,A.L., Vidal,M.
            and Zoghbi,H.Y.
  TITLE     A protein-protein interaction network for human inherited ataxias
            and disorders of Purkinje cell degeneration
  JOURNAL   Cell 125 (4), 801-814 (2006)
   PUBMED   16713569
REFERENCE   7  (bases 1 to 6526)
  AUTHORS   Jung,V., Kindich,R., Kamradt,J., Jung,M., Muller,M., Schulz,W.A.,
            Engers,R., Unteregger,G., Stockle,M., Zimmermann,R. and Wullich,B.
  TITLE     Genomic and expression analysis of the 3q25-q26 amplification unit
            reveals TLOC1/SEC62 as a probable target gene in prostate cancer
  JOURNAL   Mol Cancer Res 4 (3), 169-176 (2006)
   PUBMED   16547154
  REMARK    GeneRIF: The gene TLOC1/SEC62 revealed the highest frequency (50%)
            of copy number gains in the prostate cancer and was found to be
            up-regulated at the mRNA level.
REFERENCE   8  (bases 1 to 6526)
  AUTHORS   Meyer,H.A., Grau,H., Kraft,R., Kostka,S., Prehn,S., Kalies,K.U. and
            Hartmann,E.
  TITLE     Mammalian Sec61 is associated with Sec62 and Sec63
  JOURNAL   J Biol Chem 275 (19), 14550-14557 (2000)
   PUBMED   10799540
REFERENCE   9  (bases 1 to 6526)
  AUTHORS   Daimon,M., Susa,S. and Kato,T.
  TITLE     Fine structure of the human translocation protein 1 (HTP1/TLOC1)
            gene
  JOURNAL   IUBMB Life 48 (6), 619-624 (1999)
   PUBMED   10683767
REFERENCE   10 (bases 1 to 6526)
  AUTHORS   Daimon,M., Susa,S., Suzuki,K., Kato,T., Yamatani,K. and Sasaki,H.
  TITLE     Identification of a human cDNA homologue to the Drosophila
            translocation protein 1 (Dtrp1)
  JOURNAL   Biochem Biophys Res Commun 230 (1), 100-104 (1997)
   PUBMED   9020021
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC008040.7.
            
            On Nov 23, 2018 this sequence version replaced NM_003262.3.
            
            Summary: The Sec61 complex is the central component of the protein
            translocation apparatus of the endoplasmic reticulum (ER) membrane.
            The protein encoded by this gene and SEC63 protein are found to be
            associated with ribosome-free SEC61 complex. It is speculated that
            Sec61-Sec62-Sec63 may perform post-translational protein
            translocation into the ER. The Sec61-Sec62-Sec63 complex might also
            perform the backward transport of ER proteins that are subject to
            the ubiquitin-proteasome-dependent degradation pathway. The encoded
            protein is an integral membrane protein located in the rough ER.
            [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.159084.1,
                                           SRR1803612.203925.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000337002.9/ ENSP00000337688.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AC008040.7         136612-136663       c
            53-161              AC008040.7         127754-127862       c
            162-267             AC008040.7         126419-126524       c
            268-472             AC008040.7         120559-120763       c
            473-565             AC008040.7         120217-120309       c
            566-626             AC008040.7         117605-117665       c
            627-746             AC008040.7         115111-115230       c
            747-6526            AC008040.7         105097-110876       c
FEATURES             Location/Qualifiers
     source          1..6526
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q26.2"
     gene            1..6526
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="SEC62 homolog, preprotein translocation factor"
                     /db_xref="GeneID:7095"
                     /db_xref="HGNC:HGNC:11846"
                     /db_xref="MIM:602173"
     exon            1..52
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1216
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="translocation protein 1; membrane protein SEC62,
                     S.cerevisiae, homolog of; hTP-1; SEC62 preprotein
                     translocation factor"
                     /codon_start=1
                     /product="translocation protein SEC62"
                     /protein_id="NP_003253.1"
                     /db_xref="CCDS:CCDS3210.1"
                     /db_xref="GeneID:7095"
                     /db_xref="HGNC:HGNC:11846"
                     /db_xref="MIM:602173"
                     /translation="MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRV
                     DYFIASKAVDCLLDSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKY
                     DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK
                     KKETKKKFKLEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPA
                     EMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFWFLPNLTADVGFID
                     SFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEG
                     SGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETP
                     KSSHEKS"
     exon            53..161
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            162..267
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            268..472
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            473..565
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            566..626
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..746
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     exon            747..6526
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4588..4593
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="hexamer: AATAAA"
     regulatory      4594..4599
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="hexamer: AATACA"
     polyA_site      4613
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
     polyA_site      4618
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="major polyA site"
     regulatory      6500..6505
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
                     /note="hexamer: AATAAA"
     polyA_site      6526
                     /gene="SEC62"
                     /gene_synonym="Dtrp1; HTP1; TLOC1; TP-1"
ORIGIN      
        1 gggcggagcg gccaacatgg cggaacgcag gagacacaag aagcggatcc aggaagttgg
       61 tgaaccatct aaagaagaga aggctgtggc caagtatctt cgattcaact gtccaacaaa
      121 gtccaccaat atgatgggtc accgggttga ttattttatt gcttcaaaag cagtggactg
      181 tcttttggat tcaaagtggg caaaggccaa gaaaggagag gaagctttat ttacaaccag
      241 ggagtctgtg gttgactact gcaacaggct tttaaagaag cagttttttc accgagccct
      301 aaaagtaatg aaaatgaaat atgataaaga cataaagaaa gaaaaagata aaggaaaagc
      361 tgaaagtgga aaagaagaag ataaaaagag caagaaagaa aatataaagg atgagaagac
      421 aaaaaaagaa aaagagaaaa aaaaagatgg tgaaaaggaa gaatccaaaa aggaggaaac
      481 tccaggaact cctaaaaaga aggaaactaa gaaaaaattc aaacttgagc cacatgatga
      541 tcaggttttt ctggatggaa atgaggtgta tgtatggatc tatgacccag ttcactttaa
      601 aacatttgtc atgggattaa ttcttgtgat tgcagtaata gcggccaccc tcttccccct
      661 ttggccagca gaaatgagag taggtgttta ttacctcagt gtgggtgcag gctgttttgt
      721 agccagtatt cttctccttg ctgttgctcg atgcattcta tttctcatca tttggctcat
      781 aactggagga aggcaccact tttggttctt gccaaatctg actgctgatg tgggcttcat
      841 tgactccttc aggcctctgt acacacatga atacaaagga ccaaaagcag acttaaagaa
      901 agatgagaag tctgaaacca aaaagcaaca gaagtccgac agtgaggaaa agtcagacag
      961 tgagaaaaag gaagatgagg aggggaaagt aggaccagga aatcatggaa cagaaggctc
     1021 ggggggagaa cggcattcag acacggacag tgacaggagg gaagatgatc gatcccagca
     1081 cagtagtgga aatggaaatg attttgaaat gataacaaaa gaggaactgg aacagcaaac
     1141 agatggggat tgtgaagagg atgaggaaga ggaaaatgat ggagaaacac ctaaatcttc
     1201 acatgaaaaa tcataatctg actaattttg ggactgaatg aataagtaca agaggttgga
     1261 ttttctatgt tggctgatta ccatattgaa cacatggcat ttgtagcatt ctttaaatct
     1321 atctactgaa atgtatttga cattcaagca gttatattcg gtccttcatt ttatagaata
     1381 ttggcactat tattggtaca gtttaaagcc attaatatgt tttatccatt tgataatttt
     1441 acagtaagta ggtctcattc attttgacag ttatcaaaga tgtactttcc acagttaaat
     1501 ttacattaat ggcaattttt gatagtttta tggcttttta ctgttagact aatcaaaaat
     1561 aactttaaaa ggaacaaaga aactccaaca tttcacatta tgcatagtta tgtagccatt
     1621 tcacagtttc tttaagatgt gtaaactcat tgtccttgat agtttttatt tttcattata
     1681 aaattatacc aggagatttc ttttaagatt ctgagttagc agagttcaaa actattttgt
     1741 ggaaacaagc caactagtaa caatgcagca acacttctgg tttagctaaa ttatttttcc
     1801 aatgtaggaa atccacactg atttgtacgt ctgactgaga gaaagatggt cgtctccagc
     1861 agagaaagtg aacagcattt gttggaaggt gatggctctc cctcctccct ccccatttca
     1921 ttggcgtaac gtaaagtgta ttctgtacat aatttacaaa taaaacattt tattttaatt
     1981 gttacttatt atttagatat ttctcaacac ttaaattcat aaaattaaga ccatgtaagg
     2041 gtatgttttt agagaaatgg aagtttgagt aacccacaga acatctgtga tctttctaca
     2101 gcagcttcag ttttgtgcca acattccatg tattttgaat atgagcaaaa actgatctta
     2161 agagcagact taaagtagct ttgtacgcct taatgttcat tttgatttat tttaaatctt
     2221 tacattcaga aatgagatac tgtattatca gaccaggagg cattgctgtg aaagataatt
     2281 tcctattcta aaatatcaaa tttaaaataa agataatgaa agaaaacata agagaactat
     2341 tggactctaa ttgctttgaa ctagttttgc agtttgactt tacgtcttat acatcttagt
     2401 tacaagtctt tggaaactct tgtttactta tgagcataat cattccttgg agttatacta
     2461 actaataatg aatattaaat gatttttctt cagtcacagt gagagcatct tgctttgtgg
     2521 ttgaaatagg tagtgtatgt cagtctttgc tttaggctgt ttctcatcta agtgtttgaa
     2581 ttaaagatgt taaatttttc taattgtgaa aaatatgttt tctgtatcga cacattttat
     2641 taaacttggc ttgattgctt ctttatagta gtccctgtaa gtggacataa atgtggctat
     2701 ttgatgttaa tgcaactatg tcaaggctgc aatcacttta atagtttctt tttagcaaat
     2761 aaatgttcat tgatgaagtg cctgggtatt ttcccgtccc atttgcagag ctctactact
     2821 tcatttccac agtaagcata tatataatga tcacttctga gtttatcacc agtaacattg
     2881 atacctattt tggggtataa acatggtgtt tttcagaaat aaaaattatt tcattaacct
     2941 ttactattac tgtgataata cccaggcact caatattcat cctgaaattt tttataatat
     3001 atgtaatttg tctagtctta aagacatttg gagcatggcc aacaggaagg tcagcttctt
     3061 actgatgtgt gtggattctt acagaatgtt agtacaaatt tttataaata tttggtgatc
     3121 cctgggggga aatatcattc ttactatggt tagaaagtga attagaaatt tcagctcagt
     3181 ttctatttta ctattcaagt tgtgtacttt aaacaaatat aaaaatcaaa aggctgcctc
     3241 tattacaatc ctcagtggaa tagatggcta tctttcttgg ctaacattaa atattcttgt
     3301 accagagcat ggaaaatcgt ttataattgt taatagaatg gcgatttttt tttaagaact
     3361 tcagatttgc tatgctgctg taagtagaaa gcatgaagct ttttgatcat gtagggctta
     3421 ttgtagaggg tatcaattgg cctaactaag caggattgaa tttaccagag gctaagttca
     3481 gatagtaaga ataatgcata tgtgattgtt cttaaagtca atgtattaaa taaggtattt
     3541 ttccttttcc ctcttactgg atttttcaat tttcaaacca tatggcctag gtaactttaa
     3601 ttgaaataat atagatttag ttgaatacta ttcaggaagt aataaatttt aatatatcac
     3661 attgaaatta tgcagtggtg atgaattttg gtgtttcccc cctctttctg gttttacatc
     3721 atgaggatca gttagctgct gacaagaaaa gtcatcttgt gtcttttgta aattgaattt
     3781 tttttttaaa tctattagga actggaaaac agcaagtatg gttgattctc attattcaag
     3841 gtagttacgt tctataaagt cactgcgaac actgaattag caaatataga acctagggga
     3901 aatacaaggc tagatttctg caagccactg gtcacatttt catcaagcag tcaacatgta
     3961 aatttctgtt gtaaagacac cttatttaat ataatcgatt cattaacatt gaagtcatga
     4021 ccaacaacac tgtaactcat gcctgaatga agcttatctg acacataagc ttcataaggc
     4081 acacaacagc ctttttaccc ttaggaacag ctttttgccc ttagcactat gcttgggggc
     4141 cattttaaac agtgaaatca aaaaaagaac agaaatgcaa aaaccatggc attagcgtaa
     4201 aaaggacacg tttatagtat gaaagctgga acatggcctt gttcaacctc agctcagaat
     4261 atgtgtacag caagtttttt gctgtaccac aaaattttag gttaggcaaa ttcacaaata
     4321 cggaatccat gaataacgag gatcaactgt acttaactat attttaaagc tgtgacattt
     4381 atctacctgg tttatggaat agaatttatt gctgaatcat gctccagtat ttgagtgatg
     4441 ttttaaatat cctatgtctg aaaataattc ctcctaattg tgtggtaatt tgcttttact
     4501 gtttccacag tatttcaggt ctttgctcat tcactcagta atactgagca cttaccatgt
     4561 accagaattt tactaggcac aaccatgaat aaaaatacaa ttctcttgca ccattaaata
     4621 gtgtgttaag tgctacggca gcaaattgct acatgtgctg gatatctctt gttttcccct
     4681 ccagctccac tctgctcttg cccacaaagc tgacccgaat ggaccacagc agtgggctcc
     4741 tatgcctcct ggcttctgag tgggtttggc caaggagtgt cctggccaga gatcagagga
     4801 tggtagggtg cctattctcg gctcttctcc tggggttggg gggctgcctt agcagccaaa
     4861 ggtcacttct cccaaactcc ttccctgctt tccaggttgc cagtccctgc actcttcctt
     4921 tctggccaag gatgatgtca gttctgctgc tactagcctg gagttgcaga agctactgtg
     4981 cttcctcttt gggtagccta tacctatact tatctcctca taatatcttc atgtaaagaa
     5041 ccatctgttt cttattggaa tcaagaccaa taccaaggag aaattcctag ggaacaaaaa
     5101 ttccaatgag gaattgacct ctttgtcaga tccttatcac caaacattag aaaagatctc
     5161 ataactttat acagcatgtt gtaagcattt tgataactaa aatcctgttc tagtgaatgt
     5221 catgcagata actacacaag gagattaatt taaatttgcc ttctttggca agcccttaaa
     5281 ccaatggcta aagcagttag ttgtgagttt ctgagtaggt cccaatgcgt ttatttcatt
     5341 tgtccaacct agcacagaga tcctttgata ctttaattgc atggcttttc caatcagacg
     5401 aaatttcagt ctgagagagg acatattttc tgaggtttat agttttagga ttgtccaaaa
     5461 ggcctatgat ctcttcttag catgacagaa agagggaaag ataagttaaa tttcaagggg
     5521 gtcatatcat cacactttgg tcttatttca ttttcaatga tttcctagat cactttaact
     5581 tttttgtgtc atggactcct cagaataatg ggtttttttt gtttgtttgt ttgtttgaga
     5641 tggagtctca ctctgtcacc caggctggag tgcagtggcg aaatctcagc tcactgcaac
     5701 ctccgcctcc tgaggttcaa gtgatcctcc tgcctcagcc tcccaagtag ctgggattac
     5761 aggcacatgc caccacaccc agctaatttt tgtatttttt agtagagaca gggtttcacc
     5821 gtgttggcga gactgatctt gaactcctga catcaggtga tccacctgcc tcggcctccc
     5881 aaagtgctgg gattacaggc atgagccacc atgcctggcc agaataatgt ttttaaatgc
     5941 agaaaaggaa atgcatgggg ttacaaggga aacgaattac actgaagtgt aagctaccaa
     6001 ataatttatg atgtggtagt tataggtgtg catttaatag ccagatctac gagtggatgt
     6061 aataactgct atgatgttga agtagcataa aacatatatt agatatctgc aacaactgtg
     6121 atgtaacatg aaaatacctg atttctgttg acaaagttac tgctagtaca actgtggatt
     6181 gttgtctgca ctcgtcattg aaggaaatac taaattttag ttttaggcta gtgaaattaa
     6241 agttaatttt tcccatccaa gttcatgtat cttctgaatt ctatccgtga atcccttaga
     6301 ggtctgtgaa ttgtaggtta agaacccctg ccctagctaa tcagatccac caatgtttca
     6361 aataggacta taacttattc aaaggccaat gatacttcgc ataattcaat tttaatatta
     6421 ttcacatttc atgtcacaaa tttagtaagt tacatgtgtt atgtgatgtt ttgttttgat
     6481 agattatatc ttactcctaa ataaaaagtc aagatttttg tagcaa
//
