LOCUS       NM_001193336            3451 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens SEC14 like lipid binding 6 (SEC14L6), transcript
            variant 1, mRNA.
ACCESSION   NM_001193336 XM_001719402
VERSION     NM_001193336.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3451)
  AUTHORS   Saito,K., Tautz,L. and Mustelin,T.
  TITLE     The lipid-binding SEC14 domain
  JOURNAL   Biochim Biophys Acta 1771 (6), 719-726 (2007)
   PUBMED   17428729
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC004832.3.
            
            On Jan 27, 2021 this sequence version replaced NM_001193336.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1966682, SAMEA1968189
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000402034.7/
                                                ENSP00000385695.1
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AC004832.3         155304-155416       c
            114-189             AC004832.3         147502-147577       c
            190-233             AC004832.3         142671-142714       c
            234-293             AC004832.3         141472-141531       c
            294-482             AC004832.3         141200-141388       c
            483-578             AC004832.3         140578-140673       c
            579-639             AC004832.3         137964-138024       c
            640-723             AC004832.3         137762-137845       c
            724-830             AC004832.3         134501-134607       c
            831-970             AC004832.3         134286-134425       c
            971-1140            AC004832.3         134025-134194       c
            1141-3451           AC004832.3         131474-133784       c
FEATURES             Location/Qualifiers
     source          1..3451
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.2"
     gene            1..3451
                     /gene="SEC14L6"
                     /note="SEC14 like lipid binding 6"
                     /db_xref="GeneID:730005"
                     /db_xref="HGNC:HGNC:40047"
     exon            1..113
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1253
                     /gene="SEC14L6"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative SEC14-like protein 6; SEC14-like 6"
                     /codon_start=1
                     /product="putative SEC14-like protein 6 isoform 1"
                     /protein_id="NP_001180265.2"
                     /db_xref="CCDS:CCDS54518.1"
                     /db_xref="GeneID:730005"
                     /db_xref="HGNC:HGNC:40047"
                     /translation="MSGQVGDLSPSQEKSLAQFRENIQDVLSALPNPDDYFLLRWLQA
                     RSFDLQKSEDMLRKHMEFRKQQDLANILAWQPPEVVRLYNANGICGHDGEGSPVWYHI
                     VGSLDPKGLLLSASKQELLRDSFRSCELLLRECELQSQKLGKRVEKIIAIFGLEGLGL
                     RDLWKPGIELLQEFFSALEANYPEILKSLIVVRAPKLFAVAFNLVKSYMSEETRRKVV
                     ILGDNWKQELTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYYLCKQVRL
                     QYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTKMGERQRAREMT
                     EVLPSQRYNAHMVPEDGILTCLQAGSYVLRFYNTYSLVHSKRISYTVEVLLPDQTFME
                     KMEKF"
     exon            114..189
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            190..233
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            234..293
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            294..482
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            483..578
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            579..639
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            640..723
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            724..830
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            831..970
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1140
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..3451
                     /gene="SEC14L6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3433..3438
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC14L6"
                     /note="hexamer: AATAAA"
     polyA_site      3451
                     /gene="SEC14L6"
                     /note="major polyA site"
ORIGIN      
        1 aaaaggcagg ccacctggag ggagccacag agtggagcct ggacccattc atgggcagca
       61 tgagtggaca agtgggtgac ctgagcccat cgcaggagaa gtcgctggcc cagttccggg
      121 agaacatcca agatgtgcta tctgcgctgc ccaatcctga tgactacttc ctcctgcgct
      181 ggctccaagc tcggagcttt gacctgcaga aatcagagga catgctgagg aagcatatgg
      241 agttccggaa gcaacaagac ctggccaaca tccttgcctg gcagccccca gaggtggtca
      301 ggctgtacaa cgctaacggc atatgcggcc acgacggtga gggcagccct gtctggtacc
      361 acattgtggg aagcctggac cccaaaggcc tcttgctctc agcctccaaa caggagttgc
      421 tcagggacag cttccggagc tgcgagctgc tcctgcggga gtgtgagctg cagagtcaga
      481 agctggggaa gagggtggag aaaatcatag ctatttttgg tctcgaaggg ctgggcctga
      541 gggatctgtg gaagccagga atagagcttc tccaggagtt tttctcagca cttgaagcaa
      601 attaccctga gatcttgaag agtttaattg ttgtgagagc ccccaagcta ttcgccgtag
      661 ccttcaacct ggtcaagtct tacatgagtg aagagacacg caggaaggtg gtgattctcg
      721 gagacaactg gaagcaggag ctgacaaaat tcatcagccc cgaccagctg cccgtggagt
      781 ttggggggac catgactgac cccgatggca accccaagtg cctgaccaag atcaactacg
      841 ggggtgaggt gcccaagagc tactacctgt gcaagcaggt gaggctgcag tatgagcaca
      901 cgaggtccgt gggccgcggc tcctccctgc aggtggagaa cgagatcctg ttcccgggct
      961 gtgtgctcag gtggcagttt gcttcagatg gtggggacat tggctttggg gttttcctga
     1021 agaccaagat gggggagcgg cagagggcta gggagatgac agaggtgctg cccagccagc
     1081 gctacaatgc ccacatggtg cctgaagatg ggattctcac ctgcctccag gccggcagct
     1141 atgtcctgag gttttacaac acctacagcc tggttcattc taaacgcatc agctacaccg
     1201 tggaggtact gctcccagac caaaccttca tggagaagat ggagaaattc taggtgaacc
     1261 tcatggtccc cacaccctcc tctttgatct ctgaatccac aatgagttca cagccttccc
     1321 tggccagacc ctgttcaacc tctcaggaac agggattcta caacagcagg tcacagccta
     1381 tgcatcacag ctggcccact cctcaggaac ggctgggaca gtgtcctagt ggtggcccga
     1441 tggtcacagc aaagcaacac agacactcca tccccactat gacctgctgt gacctcaagc
     1501 tcagcaaaaa ccccaggctt ttttctatca accaatacca agaaataagt tactcttcta
     1561 aaatatagta ttaggccagg catggtggct catacctgta atcccagcac tttgggaagc
     1621 caaggcgggc agatcatttg aggtcaggag ttcgagacca gcctggccaa catggtgaaa
     1681 ccctcatctc aactaaaaat acaaaaatta gccaggtgtg atggtgcctg cttgtaattc
     1741 cagctacttg ggaggctgag gcaggagagt cgcctgaact tggtaggcag aggttgcagt
     1801 gagccgaaat catgccactg cactccagtc tgggtgacag agtgagactc tgtctcaaaa
     1861 aaataaaata aaatagtatt aataggaaat ttgaaatata gtatagctga cagatcagga
     1921 aataattacc attgaaaaga tagtttatta ctcacagttc ccaagaggag gggccgctgt
     1981 gccatagggg gaagaggagg ggtccccagg gaggcatcag ggccgaacat gacgcacatg
     2041 agacagaaaa actctggaca aagcaacttt acttttatga tggtttctgc aggaaggaac
     2101 tggtgaggca gggtaagcag gcttgagatt tgctagtttg aataatttca gcaggctccg
     2161 tggaataagg gctgtcacta gctgtctggt atcttgccct ggggtgatta cagcaggtgg
     2221 atagtggcct ggagtgtgag aatctgataa aggaggtagt tggaatatgg tttatatcag
     2281 ttggtttgca ttcgaaaagt gcatttgtgg gcaagttgct gtatctctag gagaggcagg
     2341 ccctccagga ttagcaaaac ctcagatgtt aaagcatgca gaaaataaaa gacatggttc
     2401 aaatagttcc ctaacaagca gttgtgcaat gctgctctga atggaaatcc aacctcacag
     2461 tttcccatct agaaagaatt ttaaactctc tattctgtct tccacataca cgttccctcc
     2521 cactgttata gcatctgaga atctgcttga gctctggatc ttcatccaat ctcctgatta
     2581 agatttcaaa ctggccaggt gcagtggctc acacctgtaa tcccagcact ttgggaggct
     2641 gaggcatgtg gattgctcga ggccaggagt ttgagaccag cctggacaac atggcgaaac
     2701 cccgtctcta cgaaacatac acaaattagt tgggtgtggt ggcggcgagt gcctgcagtc
     2761 ccagctactt gggaggctga ggtgggagaa tctgtggaac ccaggaggcg gaggttgcag
     2821 tgagttgaga ttgcaccact gcactccagc ctgggaaaca gagcaagacc ctgtcttaaa
     2881 aaaaaaaaat tcagactgag cctcacagtg ggacactagg tcggtgtcag cccacagtcc
     2941 tactagagtg ctgtcctgcg atcaggcctc tttgggtctg gctatgctgt cagctgagat
     3001 tctgcccagg atcctgtcac tcacatgttg tcccagcttg ttctcaatgt ggcagcccca
     3061 aatgacagcc aaagttcttc cctaattgcc tactttacag gaatcctgtc caaaaatgga
     3121 aacacgggca ttcagcagcc cttgctctcc ctcagcccct cccctgacag ccactgatct
     3181 gttcttcatc cctacacttt tgattttttc cagagtgtca tataaatgga atcgtgcaat
     3241 atttagcctt ttgattctgg ctttctttag tcagcataat gcctctgaga ttcattcact
     3301 ttgttgcatg tgttaatatt tagttgcttt tcgttgctga gtaatatacc actgtatgga
     3361 tggaccacac tgtgtttatc ccttcccctg ttaaaggctg gttgagtcgc ttccagtttg
     3421 ggggcgatta tgaataaagc tgttgtaagc a
//
