LOCUS       NM_014692               6445 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens SEC14 like lipid binding 5 (SEC14L5), mRNA.
ACCESSION   NM_014692 XM_032693 XM_940295
VERSION     NM_014692.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6445)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 6445)
  AUTHORS   Chitrala,K.N., Nagarkatti,P. and Nagarkatti,M.
  TITLE     Prediction of Possible Biomarkers and Novel Pathways Conferring
            Risk to Post-Traumatic Stress Disorder
  JOURNAL   PLoS One 11 (12), e0168404 (2016)
   PUBMED   27997584
  REMARK    GeneRIF: This analysis revealed highly connected functional
            interaction networks with two candidate genes, IL15 and SEC14L5
            highly enriched in networks. Overall, from these results, we
            concluded that these genes can be recommended as some of the
            potential targets for Post-Traumatic Stress Disorder.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6445)
  AUTHORS   Luykx,J.J., Bakker,S.C., Lentjes,E., Neeleman,M., Strengman,E.,
            Mentink,L., DeYoung,J., de Jong,S., Sul,J.H., Eskin,E., van
            Eijk,K., van Setten,J., Buizer-Voskamp,J.E., Cantor,R.M., Lu,A.,
            van Amerongen,M., van Dongen,E.P., Keijzers,P., Kappen,T.,
            Borgdorff,P., Bruins,P., Derks,E.M., Kahn,R.S. and Ophoff,R.A.
  TITLE     Genome-wide association study of monoamine metabolite levels in
            human cerebrospinal fluid
  JOURNAL   Mol Psychiatry 19 (2), 228-234 (2014)
   PUBMED   23319000
REFERENCE   4  (bases 1 to 6445)
  AUTHORS   Saito,K., Tautz,L. and Mustelin,T.
  TITLE     The lipid-binding SEC14 domain
  JOURNAL   Biochim Biophys Acta 1771 (6), 719-726 (2007)
   PUBMED   17428729
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB007880.2, AC007011.1 and AC026458.8.
            
            On Nov 23, 2018 this sequence version replaced NM_014692.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.187991.1, AB007880.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2154665
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000251170.12/ ENSP00000251170.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1267              AB007880.2         14-1280
            1268-1270           AC007011.1         83215-83217         c
            1271-2642           AB007880.2         1284-2655
            2643-6443           AC026458.8         3762-7562
            6444-6445           AC026458.8         7563-7564
FEATURES             Location/Qualifiers
     source          1..6445
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..6445
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /note="SEC14 like lipid binding 5"
                     /db_xref="GeneID:9717"
                     /db_xref="HGNC:HGNC:29032"
                     /db_xref="MIM:619412"
     exon            1..116
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            117..230
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..2258
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /note="SEC14-like 5"
                     /codon_start=1
                     /product="SEC14-like protein 5"
                     /protein_id="NP_055507.1"
                     /db_xref="CCDS:CCDS45403.1"
                     /db_xref="GeneID:9717"
                     /db_xref="HGNC:HGNC:29032"
                     /db_xref="MIM:619412"
                     /translation="MVQRYQSPVRVYKYPFELVMAAYEKRFPTCPQIPVFLGSEVLRE
                     SRSPDGAVHVVERSCRLRVDAPRLLRKIAGVEHVVFVQTNILNWKERTLLIEAHNETF
                     ANRVVVNEHCSYTVHPENEDWTCFEQSASLDIRSFFGFENALEKIAMKQYTANVKRGK
                     EVIEHYLNELISQGTSHIPRWTPAPVREEDARNQAGPRDPSSLEAHGPRSTLGPALEA
                     VSMDGDKLDADYIERCLGHLTPMQESCLIQLRHWLQETHKGKIPKDEHILRFLRAHDF
                     HLDKAREMLRQSLSWRKQHQVDLLLQTWQPPALLEEFYAGGWHYQDIDGRPLYILRLG
                     QMDTKGLMKAVGEEALLRHVLSVNEEGQKRCEGSTRQLGRPISSWTCLLDLEGLNMRH
                     LWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLISPFINENTRRKFLIY
                     SGSNYQGPGGLVDYLDREVIPDFLGGESVCNVPEGGLVPKSLYMTEEEQEHTDQLWQW
                     SETYHSASVLRGAPHEVAVEILEGESVITWDFDILRGDVVFSLYHTKQAPRLGAREPG
                     TRASGQLIDKGWVLGRDYSRVEAPLVCREGESIQGSHVTRWPGVYLLQWQMHSPPSSV
                     ACSLPGVDDVLTALHSPGPKCKLLYYCEVLASEDFRGSMSSLESCTSGFSQLSAATSS
                     SSSGQSHSSSLVSR"
     exon            231..380
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            381..512
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            513..641
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            642..834
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            835..947
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1137
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1226
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1297
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1469
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1604
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1739
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..1967
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..2146
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..6445
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      6445
                     /gene="SEC14L5"
                     /gene_synonym="PRELID4B"
                     /note="major polyA site"
ORIGIN      
        1 ctctcggccc ggcaggtttc gctcccgccc ctccggcctt ccacagctgt cctggccgca
       61 gggtgttcaa ggcgggacac accaggctag agatccgcga tcgggccccg cctcaggctc
      121 tgtgcacacc cctgcctggt gacctccatt ggtgctccag cgtgaacatg gtgcaaagat
      181 accagtctcc tgtccgagtc tacaagtacc cgtttgagct ggtcatggcg gcctacgaga
      241 agcgtttccc cacgtgccca cagatcccag tcttcctggg cagcgaggtc ttgcgcgagt
      301 cccgcagccc ggacggggct gtgcacgtgg tggagcggag ctgccggctg cgcgtggacg
      361 ccccgcggct gctgcggaag atcgcaggtg ttgagcacgt ggtcttcgtg cagacaaaca
      421 tcttgaactg gaaggagagg acgctcctca tcgaagcgca caatgagacc ttcgccaacc
      481 gcgtggtggt gaacgagcac tgcagctaca cggtccaccc tgagaatgaa gactggactt
      541 gcttcgagca gtctgcctca ctggacattc ggtctttctt tggctttgaa aatgccttgg
      601 agaagatcgc catgaagcag tacaccgcca acgtcaagag ggggaaggag gtgattgagc
      661 attacctgaa tgagctcatc tcccagggta cctcgcacat tccgcgctgg acgcctgccc
      721 cagtccgtga ggaggatgcc cgcaaccagg ctggaccgag ggaccccagc tccctggagg
      781 cccacgggcc ccgtagcacc ctggggcccg ctctggaggc ggtcagtatg gacggggaca
      841 agctggatgc ggactacatt gagaggtgcc tgggccacct cacgcccatg caggagagct
      901 gcctgatcca gcttcggcac tggttacagg agacccacaa aggcaagatt cccaaagatg
      961 agcacatcct tcggttcctg cgggctcatg acttccacct ggacaaggcc cgggaaatgc
     1021 tgcgccagtc cttgagctgg cgcaagcagc accaggtgga tctcctcctt cagacctggc
     1081 aaccccctgc cctgctggag gagttctatg cagggggctg gcattaccag gacatagatg
     1141 gccgccccct ctacatcctc cgcctgggcc agatggacac caaaggcttg atgaaggccg
     1201 tgggggagga ggcgctgctg cggcatgttc tctccgtcaa cgaggaagga cagaagcggt
     1261 gtgaggggag cacaaggcag ctgggccgtc ccatcagctc ctggacctgc ctgctagacc
     1321 tggagggact caacatgcgg cacctgtggc ggccgggggt gaaggccctg ctgcggatga
     1381 ttgaggtggt tgaggacaat tacccagaga ccctgggtcg gctgctcatc gtgcgagccc
     1441 cccgagtctt ccccgtgctc tggacactga tcagcccctt catcaatgag aacaccaggc
     1501 ggaagttcct catctacagt ggcagcaact accagggacc cggaggcctt gtggactatc
     1561 tggatagaga agtgatccct gacttccttg ggggagagag tgtgtgtaat gtccccgaag
     1621 gagggctggt ccccaagtcc ctctacatga cagaagagga gcaggagcac acggaccagc
     1681 tgtggcagtg gagtgagacc taccattcag ccagcgtgct ccgcggagcc ccccacgagg
     1741 tggccgtgga gatcctggaa ggagagtcgg tcatcacctg ggactttgac atcctgcgag
     1801 gggacgtggt gttcagcctg taccacacca agcaggcgcc caggctgggc gcccgggaac
     1861 cggggaccag ggccagcggg cagctgatcg acaaaggctg ggtcctgggc agggattaca
     1921 gccgtgtgga ggctcccctt gtctgccggg agggggagag catccagggc tcccatgtga
     1981 cccggtggcc cggcgtctac ctgctccagt ggcaaatgca cagccccccc agcagcgtgg
     2041 cctgcagcct cccgggtgtg gacgatgtcc tgacggctct gcacagcccc gggcccaagt
     2101 gcaaacttct ctactactgt gaggtgctcg cctctgagga cttcaggggc tccatgtcca
     2161 gcctggaatc ctgcaccagc ggcttctccc agctcagcgc cgccacctcg tcctcctcct
     2221 ccggccagtc tcatagcagc tccctggtct ccagatagcc gggcccagtg tttcagggcc
     2281 gcccgctcgc ctccagtgtc cagaaatgtc cagaatgaga agccagctaa ctgcagggcc
     2341 tgggaccatg tgggctggag ccccaggcct agatgctgcc caagttgggg tgtctggagc
     2401 ggatggcaag gatccagaac tggcctgtgg gtggtgtcag ggctcttgaa attgcaagga
     2461 cagaaccatc tccttccggc ttcgtgtaag gaagaccaag ccaaggccaa ggtgtctacc
     2521 ataccacacc tttgggacat ccgggcttag cgacgtcagc caggcccatc tcctctctgt
     2581 ccacctcttg ctctgctttc gccatgcagg ggaccatcac tatcaggtgc ccttctcctc
     2641 cctgcagctt gcctgcataa gagagcctct tcctcccaaa ggctccagcc cacttcccag
     2701 agctgagtct tagcctggaa gggggagcga ttgccaggtc aattcctgaa ccaatcacag
     2761 ttgccaggca cactggagaa tgctgattgg ccagcagggt catgcccaat ctggaccaat
     2821 caccgtgatc cagggttgca gtgaggtgca gtgattggcc agcctggatc acatgcacat
     2881 ctctggaacc aaccacctgc tctcaaaagc actagtgggt gcctcgagga gtactggggt
     2941 cccccctaag aagaaggagg aaggatgctg gggaggcaga aatgaagggt gtttaccttg
     3001 gcatctgatt gcataacgtt ctgttatgca gtatcaagat gtgcttggtg agcagttaag
     3061 tgagttacag gcgctgctct ttgtggggaa cagcacatcc tgaagtgaaa atccatgttc
     3121 cctgcacttg gccagcatgg cctaagcctg accatccctg attggagagg gtgggagagc
     3181 cctgggtttc tgctaagttc caggcagtga tggggtgact gaggctgtct gtatacccca
     3241 ctggagatgc ctttctctcc tagggaactg tttaattatg actgtttttg gttgtaagcc
     3301 acagagaccc atgcccaggt gcttcaacac aaaagcatga tcattcatgg gtgcatagaa
     3361 ctggccagtc caggagggct tgcttcaggt aaggctagat ccagggtctc aacatggagt
     3421 ctcgattccc cccgcgagtg gaggctgctg tgtttgccct ggggcagata tgactctgga
     3481 actaggttca atattgacat gagttcccct agttactaca caggagcgtc ttgggtctcc
     3541 ttggggcctg aggacatttc tcctttcctt tcctggactc cccaaaaggc agccagtcag
     3601 gggtcaccaa cttgaagcct gatctggcct gcttttagtg ttgctttttt gcctttagaa
     3661 tggtttaaaa attgaggcat ttcgcatcga aatcaggatt tctggcttcc cttaggcatt
     3721 tgggagcacc agcagaatgg ggtcactatt gttgcatgaa gacaacacct ctgcacccct
     3781 ggatgtggcc acgccagtcc ctaccccatt gacttgcgcc cagcccacat tacacatcct
     3841 catgacctgc gtggcaggag tctcactgac atggctctgt cagcagtggc tggtaccctt
     3901 gtctcctggc cttgcttaga gttggggctc atctctgctg cagtaactga gccaaggggt
     3961 ggttttgtgg ccacaagaat catctttatg caggctcagc aatgcagggc caggaaactt
     4021 atatctacgc cagcctcaac cccaaaccca aggaagagag aaagtgtcat cttttcagat
     4081 acatccttct tcctgctggg agagagcctt gcccaccttc ctgttggctc tctgtccgct
     4141 tctcaggtat ctgaacaaaa tagattgctt tgcactctgc gtcaaggtgt gtgtgcacat
     4201 gtgtgcataa gagaccgact gattggaagg agacgttctc aaaactaatt gctcccatat
     4261 caccaggcat ttattgctga gagcaacttg caatattttc aactatcttt aagtgaattt
     4321 ctagcttttc tcttaaaaac taggtgttat cctacaagta tgctgggata agctgccctg
     4381 gcagtcttta tacatttatt gtctagcccc agagaaggac acagaagcct tttacggaag
     4441 gaagctggaa ctgcctgttc cagaggcggg tggggggagg ggagtctgct atcagctgtc
     4501 cacccttaac agtgggggtg aggaacctca ggccctttca gttctgctct tgagagtgct
     4561 ctctccctag ggaaaaccag cccaaactgg cttaagcaac aaagcaaatt ccctgggtcc
     4621 tgtactaggg atggctgaag gtgggtgctg cttcagatat ggctggatcc aggagcttaa
     4681 tgtcctcagg cctctcaact gcacccaggc ctcttgactc tgcatctctt tgcatgctga
     4741 cctcattctt tcttccacct ggcgggaaag atggctgcca gcagccccaa gcctataatt
     4801 tcaggattca cactctaaga gatgcttttc catctcaaat ctcatggaag gctctgattg
     4861 gcccagctcg agtcacatgc ttattcctgt gggccacact ggcaaggaac tagggtcccg
     4921 tgattgacat tccctgcaga agccgcagca ggattgggga gggccattcc cccaatggac
     4981 aagagaagct ggaccacaga accagcaggt atccatggtg gcatctgcta cggccggctc
     5041 tcctcccatg tggaggtctc ggggacccac gtggaagcat tatcaaggtc attcttcttg
     5101 ccttcgggag gactggaatt aaaaataatc caaggaaggg attgccaagc ttttggcttt
     5161 tgaatttccc ctgagccaca aaggctggaa gtgccttggc ttgggcttct tgcatcatta
     5221 gttcattaat ccattgtgac caggacagaa gcaacccaca agcagcatta ctgttggtgt
     5281 ttgggcacct gggccttgaa tttaggccag gactcaaacc ccagccttcc tttcactagc
     5341 tgtgtaacct tgaccaggtg acttaacctc tctgtgcctc agtttcctca tctgtaaagt
     5401 gaggatagca gtgcctacct caataggttg tagtgggacg aaatgaggga gtagctgtaa
     5461 agctttcagc acagctccca gaacacagaa agcgctccat taatgtcagt ggtcattctg
     5521 attacttaat gcttcgcatc caaagactcg ttttcttcct gaggtcgcct atccctgttt
     5581 ttcgttattg cacccagaga aaagtaggtg tcaagaatta ttgccctctg agttgggtgt
     5641 gcagtctttc tcttttagaa actgcttgtg tgggcggggc gtggtggctc atgcctataa
     5701 tcccaacact ttgggaggct gaggccggct gatcgcttga gtgcaggagt tcaagaccag
     5761 cctgggcaac atagtgagac cctgtctcta caaaaaatta aaaaatgagc caggcgtggt
     5821 ggtgcgtgcc tatagtctca gctgctcggg aggctgaggc agaaggattg cttggaggtc
     5881 aaggctggag tgagccatga tctcacccct gtacttcatc ctgggtgaca aagcaagacc
     5941 ctgtctcaaa aaaagaagaa agaagctgct tgtgttttct gggtaagtcc acccatctga
     6001 gggagtgtat tctgagtggt atttcccttg gcagttagaa aatgtttttt cccagaggtt
     6061 gaagtatgga gagtttgaga ctcttttttt ctaccctgca ctctctggaa ttccccctcc
     6121 ctgctgtaaa atttattgtc caatgagaat agtataattg ttttcaacaa agtctctttg
     6181 agccagtgaa acacgatggg tttttttgtt tgcctgatca cttgctccaa ccagcagcat
     6241 taaatgtttt ccatttggat aaacttgcat cgtcagcttc ctaaaaccct ggaggtttcc
     6301 cgtgggctcg ttcaagaact ttccagctgt tgtttaaaag actttagagc tagcttgttc
     6361 agcctgtggc ctgcaggctg cacgcggccc cggactgctt tgaatgtgct ccaacacgag
     6421 ttcgtaaact ttcttaaaat actga
//
