LOCUS       NM_001143999            5496 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens SEC14 like lipid binding 1 (SEC14L1), transcript
            variant 4, mRNA.
ACCESSION   NM_001143999
VERSION     NM_001143999.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5496)
  AUTHORS   Banet,N., Masnick,M. and Quddus,M.R.
  TITLE     Evaluation of Saccharomyces cerevisiae -like 1 (SEC14L1) in
            Gynecologic Malignancies Shows Overexpression in Endometrial Serous
            Carcinoma
  JOURNAL   Int J Gynecol Pathol 42 (2), 136-142 (2023)
   PUBMED   35283446
  REMARK    GeneRIF: Evaluation of Saccharomyces cerevisiae -like 1 (SEC14L1)
            in Gynecologic Malignancies Shows Overexpression in Endometrial
            Serous Carcinoma.
REFERENCE   2  (bases 1 to 5496)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 5496)
  AUTHORS   Sonbul,S.N., Aleskandarany,M.A., Kurozumi,S., Joseph,C., Toss,M.S.,
            Diez-Rodriguez,M., Nolan,C.C., Mukherjee,A., Martin,S., Caldas,C.,
            Ellis,I.O., Green,A.R. and Rakha,E.A.
  TITLE     Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in
            breast cancer associated with lymphovascular invasion
  JOURNAL   Mod Pathol 31 (11), 1675-1682 (2018)
   PUBMED   29955149
  REMARK    GeneRIF: Our findings specify SEC14L1 as an independent prognostic
            factor in breast cancer.
REFERENCE   4  (bases 1 to 5496)
  AUTHORS   Filipuzzi,I., Cotesta,S., Perruccio,F., Knapp,B., Fu,Y., Studer,C.,
            Pries,V., Riedl,R., Helliwell,S.B., Petrovic,K.T., Movva,N.R.,
            Sanglard,D., Tao,J. and Hoepfner,D.
  TITLE     High-Resolution Genetics Identifies the Lipid Transfer Protein
            Sec14p as Target for Antifungal Ergolines
  JOURNAL   PLoS Genet 12 (11), e1006374 (2016)
   PUBMED   27855158
  REMARK    GeneRIF: we present genetic evidence that NGx04 inhibits fungal
            Sec14p and initial data supporting NGx04 as a novel antifungal
            starting point.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5496)
  AUTHORS   Burdelski,C., Barreau,Y., Simon,R., Hube-Magg,C., Minner,S.,
            Koop,C., Graefen,M., Heinzer,H., Sauter,G., Wittmer,C., Steurer,S.,
            Adam,M., Huland,H., Schlomm,T., Tsourlakis,M.C. and Quaas,A.
  TITLE     Saccharomyces cerevisiae-like 1 overexpression is frequent in
            prostate cancer and has markedly different effects in Ets-related
            gene fusion-positive and fusion-negative cancers
  JOURNAL   Hum Pathol 46 (4), 514-523 (2015)
   PUBMED   25701228
  REMARK    GeneRIF: a markedly different role of SEC14L1 in
            TMPSSR2:ERG-negative and TMPSSR2:ERG-positive prostate cancers
REFERENCE   6  (bases 1 to 5496)
  AUTHORS   Need,A.C., Attix,D.K., McEvoy,J.M., Cirulli,E.T., Linney,K.L.,
            Hunt,P., Ge,D., Heinzen,E.L., Maia,J.M., Shianna,K.V., Weale,M.E.,
            Cherkas,L.F., Clement,G., Spector,T.D., Gibson,G. and
            Goldstein,D.B.
  TITLE     A genome-wide study of common SNPs and CNVs in cognitive
            performance in the CANTAB
  JOURNAL   Hum Mol Genet 18 (23), 4650-4661 (2009)
   PUBMED   19734545
REFERENCE   7  (bases 1 to 5496)
  AUTHORS   Saito,K., Tautz,L. and Mustelin,T.
  TITLE     The lipid-binding SEC14 domain
  JOURNAL   Biochim Biophys Acta 1771 (6), 719-726 (2007)
   PUBMED   17428729
  REMARK    Review article
REFERENCE   8  (bases 1 to 5496)
  AUTHORS   Ribeiro,F.M., Ferreira,L.T., Marion,S., Fontes,S., Gomez,M.,
            Ferguson,S.S., Prado,M.A. and Prado,V.F.
  TITLE     SEC14-like protein 1 interacts with cholinergic transporters
  JOURNAL   Neurochem Int 50 (2), 356-364 (2007)
   PUBMED   17092608
REFERENCE   9  (bases 1 to 5496)
  AUTHORS   Kalikin,L.M., Bugeaud,E.M., Palmbos,P.L., Lyons,R.H. Jr. and
            Petty,E.M.
  TITLE     Genomic characterization of human SEC14L1 splice variants within a
            17q25 candidate tumor suppressor gene region and identification of
            an unrelated embedded expressed sequence tag
  JOURNAL   Mamm Genome 12 (12), 925-929 (2001)
   PUBMED   11707779
REFERENCE   10 (bases 1 to 5496)
  AUTHORS   Chinen,K., Takahashi,E. and Nakamura,Y.
  TITLE     Isolation and mapping of a human gene (SEC14L), partially
            homologous to yeast SEC14, that contains a variable number of
            tandem repeats (VNTR) site in its 3' untranslated region
  JOURNAL   Cytogenet Cell Genet 73 (3), 218-223 (1996)
   PUBMED   8697811
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC068594.15.
            
            On Jun 1, 2019 this sequence version replaced NM_001143999.1.
            
            Summary: The protein encoded by this gene belongs to the SEC14
            cytosolic factor family. It has similarity to yeast SEC14 and to
            Japanese flying squid RALBP which suggests a possible role of the
            gene product in an intracellular transport system. Multiple
            alternatively spliced transcript variants have been found for this
            gene; some variants represent read-through transcripts that include
            exons from the upstream gene C17orf86. [provided by RefSeq, Feb
            2011].
            
            Transcript Variant: This variant (4) differs in the 5' UTR,
            compared to variant 3. Variants 1, 3, 4 and 7 encode isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR1803611.225242.1, SRR1803617.144345.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1965299, SAMEA1968540 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AC068594.15        10144-10282
            140-240             AC068594.15        11825-11925
            241-333             AC068594.15        12742-12834
            334-483             AC068594.15        59978-60127
            484-615             AC068594.15        60356-60487
            616-744             AC068594.15        62596-62724
            745-979             AC068594.15        63852-64086
            980-1089            AC068594.15        65377-65486
            1090-1279           AC068594.15        69659-69848
            1280-1368           AC068594.15        72745-72833
            1369-1439           AC068594.15        74451-74521
            1440-1611           AC068594.15        75404-75575
            1612-1746           AC068594.15        75903-76037
            1747-1881           AC068594.15        78517-78651
            1882-2133           AC068594.15        81125-81376
            2134-2312           AC068594.15        82489-82667
            2313-5496           AC068594.15        83093-86276
FEATURES             Location/Qualifiers
     source          1..5496
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.2-q25.3"
     gene            1..5496
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /note="SEC14 like lipid binding 1"
                     /db_xref="GeneID:6397"
                     /db_xref="HGNC:HGNC:10698"
                     /db_xref="MIM:601504"
     exon            1..139
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            140..240
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            241..333
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     CDS             271..2418
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /note="isoform a is encoded by transcript variant 4;
                     SEC14-like protein 1"
                     /codon_start=1
                     /product="SEC14-like protein 1 isoform a"
                     /protein_id="NP_001137471.2"
                     /db_xref="GeneID:6397"
                     /db_xref="HGNC:HGNC:10698"
                     /db_xref="MIM:601504"
                     /translation="MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNE
                     FKSEDGAIHVIERRCKLDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETF
                     SNRVIINEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGK
                     EIIEYYLRQLEEEGITFVPRWSPPSITTSSETSSSSSKKQAASMAVVIPEAALKEGLS
                     GDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPK
                     DEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHH
                     DKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSW
                     TCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSP
                     FIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCEVPEGGLVPKSLYRT
                     AEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYH
                     SKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSH
                     VTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRG
                     SMTSLESSHSGFSQLSAATTSSSQSHSSSMISR"
     exon            334..483
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            484..615
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            616..744
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            745..979
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1089
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1279
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1368
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1439
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1611
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1746
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1881
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2133
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            2134..2312
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..5496
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2703..2708
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /note="hexamer: ATTAAA"
     polyA_site      2727
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
     regulatory      5471..5476
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /note="hexamer: AATAAA"
     polyA_site      5496
                     /gene="SEC14L1"
                     /gene_synonym="PRELID4A; SEC14L"
                     /note="major polyA site"
ORIGIN      
        1 cccgcctccc cggccccctc cccggaaccg gcggtcgagc tacggtcgcg gagcagtgga
       61 accgagactg ccccgcggag ccgccggtat gagcgcccct cgccaccccg tgtcccaggc
      121 ccggcctttc tgacaagaga cttcgggctc cttgaggata ttcagttttg tatgtttgaa
      181 tatcctctca ccatgttcag cataaagtac cattcttaat gattatcctc aacaagacag
      241 gtgtgagagg gttgctgttg tattgcaatc atggtgcaga aataccagtc cccagtgagg
      301 gtgtacaaat acccctttga attaattatg gctgcctatg aaaggaggtt ccctacatgt
      361 cctttgattc cgatgttcgt gggcagtgac actgtgaatg aattcaagag cgaagatggg
      421 gctattcatg tcattgaaag gcgctgcaag ctggatgtag atgcacccag actgctgaag
      481 aagattgcag gagttgatta tgtttatttt gtccagaaaa actcactgaa ttctcgggaa
      541 cgtactttgc acattgaggc ttataatgaa acgttttcca atcgggtcat cattaatgag
      601 cattgctgct acaccgttca ccctgaaaat gaagattgga cctgttttga acagtctgca
      661 agtttagata ttaaatcttt ctttggtttt gaaagtacag tggaaaaaat tgcaatgaaa
      721 caatatacca gcaacattaa aaaaggaaag gaaatcatcg aatactacct tcgccaatta
      781 gaagaagaag gcataacctt tgtgccccgt tggagtccgc cttccatcac gacctcttca
      841 gagacatctt catcatcctc caagaaacaa gcagcgtcca tggccgtcgt catcccagaa
      901 gctgccctca aggaggggct gagtggtgat gccctcagca gccccagcgc acctgagccc
      961 gtggtgggca cccctgacga caaactagat gccgactaca tcaagagata cctgggcgat
     1021 ttgactccgc tgcaggagag ctgcctcatt agacttcgcc agtggctcca ggagacccac
     1081 aagggcaaaa ttccaaaaga tgagcatatt cttcggttcc tccgtgcacg ggattttaat
     1141 attgacaaag ccagagagat catgtgtcag tctttgacgt ggagaaagca gcatcaggta
     1201 gactacattc ttgaaacctg gacccctcct caggtccttc aggattacta cgcgggaggc
     1261 tggcatcatc acgacaaaga tgggcggccc ctctacgtgc tcaggctggg gcagatggac
     1321 accaaaggct tggtgagagc gctcggggag gaagccctgc tgagatacgt tctctccata
     1381 aatgaagaag ggctaaggcg atgcgaagag aatacaaaag tctttggtcg gcctatcagc
     1441 tcatggacct gcctggtgga cttggaaggg ctgaacatgc gccacttgtg gagacctggt
     1501 gtgaaagcgc tgctgcggat catcgaggtg gtggaggcca actaccctga gacactgggc
     1561 cgccttctca tcctgcgggc gcccagggta tttcctgtgc tctggacgct ggttagtccg
     1621 ttcattgatg acaacaccag aaggaagttc ctcatttatg caggaaatga ctaccagggt
     1681 cctggaggcc tgctggatta catcgacaaa gagattattc cagatttcct gagtggggag
     1741 tgcatgtgcg aagtgccaga gggtggactg gtccccaaat ctctgtaccg gactgcagag
     1801 gagctggaga acgaagacct gaagctctgg actgagacca tctaccagtc tgcaagcgtc
     1861 ttcaaaggag ccccacatga gattctcatt cagattgtgg atgcctcgtc agtcatcact
     1921 tgggatttcg acgtgtgcaa aggggacatt gtgtttaaca tctatcactc caagaggtcg
     1981 ccacaaccac ccaaaaagga ctccctggga gcccacagca tcacctctcc gggtgggaac
     2041 aatgtgcagc tcatagacaa agtctggcag ctgggccgcg actacagcat ggtggagtcg
     2101 cctctgatct gcaaagaagg agaaagcgtg cagggttccc atgtgaccag gtggccgggc
     2161 ttctacatcc tgcagtggaa attccacagc atgcctgcgt gcgccgccag cagccttccc
     2221 cgggtggacg acgtgcttgc gtccctgcag gtctcttcgc acaagtgtaa agtgatgtac
     2281 tacaccgagg tgatcggctc ggaggatttc agaggttcca tgacgagcct ggagtccagc
     2341 cacagcggct tctcccagct gagtgccgcc accacctcct ccagccagtc ccactccagc
     2401 tccatgatct ccaggtagtg ccgcgctgcc tgcacctagt gtgcagaggg gacggccgcc
     2461 cctcctcgga cagccagctg cacccgccca cccagcggcg acattgtaca gactcctctc
     2521 acctctagat agcaaatagc tctcagatgg taaacgtagt cgtttgatcc caaaactacc
     2581 ttggcaggta gttttaactc tgatcctaac ttaactcaat agccatagat tttgtatacg
     2641 ttgtgcacaa aatccaacca gagcgcaagg gctctcttga aagaaaagta gtttctgtac
     2701 caattaaagg attgacgtgg tctcagatat tgatgcaaaa aatttttcca acgaactccg
     2761 cattgtccat tagtgaatga attcctgtga catcctccag agatggcccc tcctcacctg
     2821 ggacggaagc tgccagctcg cttcccccaa gctgcctcat ggcccgcacg ccgcctcacg
     2881 gcccccatgc ttcccgccag tcaagatggt ctgtggactt agggccagcc cttgaggtcc
     2941 ttatcctctg aggattcaga ggttgcctgc ggagtacctt gtcccagggc cagacacacc
     3001 cacaccaccc actgtcctgc agtggggccg ggggctcagg aggggctctc agggactcct
     3061 ggtgactcca ggaaaatgct gccatcgtta aacattactt tctctttcct ccttttcaaa
     3121 tctttttgat actttttaga gcaggatttt tctgtatgtg aacttgggtg ggggggttct
     3181 tcccgtttcc ttccgtgcgt cgcccctctc acctgcagtc agctcccagc ccagtgtagg
     3241 ccatctcctc tgtgccctct ggtggctcat tgtcctcaga gcccagacag ttccagccac
     3301 taggaggccg tcttggaacc agcaagtcgc atttgccact tgacactgtc catggggttt
     3361 tattagtagc taagcagcag ctctcgcatc cacttcaggg tggcgtgtgg catgtaggag
     3421 tcctgcttct ttgtacatgg gaattgtgga ctcatgcgtg tgtgtgtgtg catgtgctgt
     3481 gtgtgtgcat gtgtgcatga cggtgggggt gctgggggga cggggtgagt ggaaacttag
     3541 tttgagtaat gaaggaatct tcacagaagc aaatcagaat atgggatttg tttgcctttt
     3601 acattttgtt taattcctga ttttaaagcc tgctctatct ggtacaggcc cttatttttt
     3661 cagcttttta tgggaaaagc aggttatttg agaatctgtc cagaagttgc ataggggatg
     3721 gcctccacga taaggacatg caacacgtgt ttctgtgtgc agcagaggcc gtgtttttca
     3781 tgccaaaccc cacgcggctg tcaactgtgt gcgtggtagg catggagatc ctggttgtgc
     3841 cgtctcagct ccgctctgaa ggcactgtgt gggtgctgcg tgactggaga gctgtgtgga
     3901 ggccatgtgt gccccgtgca gggatcagga gggcggggga gggaccgagc agccctcttg
     3961 cccggtcggg tcagccctag tggctgcctg cacactgtag acgtcccagg gcctgtgctg
     4021 tgatcacctg cctttggacc acatttgtgt ttgctcttag agatcgagct cctcagtggt
     4081 acctgaagcc tttgcttccg gaaagcgcgg tagggttcgt aggtagggct agtaggtagg
     4141 gttagtaggt agggctagta ggtagggcta gtaggtaggg ttcgtaggta gggttcgtag
     4201 gtagggctgg taggtagggt tagtaggtag ggctagtagg tagggttagt aggtagggtt
     4261 cgtaggtagg gttcgtaggt agggttcgta ggtagggcta gtaggtaggg ttagtaggta
     4321 gggttcgtag gtagggttcg taggtagggt taggtagggt tcgtaggtag ggttagtagg
     4381 tagggctagt aggtagggtt cgtaggtagg gttcgtaggt agggctagta ggtagggtta
     4441 gtaggtaggg ctagtaggta gggctagtag gtagggttag taggtagggc tagtaggtag
     4501 ggttcgtagg tagggttagt aggtagggct agtaggtagg gttcgtaggt agggttcgta
     4561 ggtagggcta gtaggtaggg ttagtaggta gggctagtag gtagggctag taggtagggt
     4621 tcgtaggtag ggttcgtagg tagggttcgt aggtagggtt cgtaggtagg gttagtaggt
     4681 agggttcgta ggtagggcta gtaggtaggg ctagtaggta gggctagtag gtagggttag
     4741 taggtagggc tagtaggtag ggctagtagg tagggctagt aggtagggct agtaggtagg
     4801 gttcgtaggt agggttcgta ggtagggttc gtaggtaggg ttagtagcgc gtctgtgctg
     4861 cttccacctg gtgcttcctg ttcccaaatc acaagggcct gaaggtggtc cctgctttct
     4921 ctttctcttt ctctgtgtct cagatggcga ttttgctgac agctgccaag aaaatgcttc
     4981 actcaacagt cctcatgtgc ccagagatgt ttatagaact gtttgaattg cagccatccc
     5041 ctgccccctc ccaggctgaa gatctgttct ttttaagttg attcgggagt ggcattcttt
     5101 tatacccaaa gactgtagtg catcttgaag agctcaaagc acatgaccgc acaaatgctt
     5161 acagggtttc ctcccgagta atccaatctc actccccttg taagggaatt ctggggcagc
     5221 tatggtttga gtatgcagtt tgcatcgtgt ttctaccttt agtaccttgc cactctttta
     5281 aaacgctgct gtcatttccc atttcttagt actaatgatt ctttgattct ccctctatta
     5341 tgtcttaatt cactttcctt cctaaatttg ttatttgcat atcaaattct gtaaatgttt
     5401 tgtaaacata ttacctcact tggtaataca atactgatag tctttaaaag atttttttat
     5461 tgttatcaat aataaatgtg aactatttaa agaaaa
//
