LOCUS       NM_178483                596 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens SCP2 sterol binding domain containing 1 (SCP2D1),
            mRNA.
ACCESSION   NM_178483
VERSION     NM_178483.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Edqvist,J. and Blomqvist,K.
  TITLE     Fusion and fission, the evolution of sterol carrier protein-2
  JOURNAL   J Mol Evol 62 (3), 292-306 (2006)
   PUBMED   16501878
REFERENCE   2  (bases 1 to 596)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF418570.1.
            
            On May 17, 2019 this sequence version replaced NM_178483.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BX097724.1, SRR5189667.106895.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377428.4/ ENSP00000366645.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-596               AF418570.1         58-653
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20p11.23"
     gene            1..596
                     /gene="SCP2D1"
                     /gene_synonym="C20orf79; dJ1068E13.2; HSD22"
                     /note="SCP2 sterol binding domain containing 1"
                     /db_xref="GeneID:140856"
                     /db_xref="HGNC:HGNC:16211"
     exon            1..596
                     /gene="SCP2D1"
                     /gene_synonym="C20orf79; dJ1068E13.2; HSD22"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..504
                     /gene="SCP2D1"
                     /gene_synonym="C20orf79; dJ1068E13.2; HSD22"
                     /note="sterol carrier protein 2-like protein"
                     /codon_start=1
                     /product="SCP2 sterol-binding domain-containing protein 1"
                     /protein_id="NP_848578.1"
                     /db_xref="CCDS:CCDS13139.1"
                     /db_xref="GeneID:140856"
                     /db_xref="HGNC:HGNC:16211"
                     /translation="MWKRSDHQPKIKAEDGPLVGQFEVLGSVPEPAMPHPLELSEFES
                     FPVFQDIRLHIREVGAQLVKKVNAVFQLDITKNGKTILRWTIDLKNGSGDMYPGPARL
                     PADTVFTIPESVFMELVLGKMNPQKAFLAGKFKVSGKVLLSWKLERVFKDWAKF"
     regulatory      576..581
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SCP2D1"
                     /gene_synonym="C20orf79; dJ1068E13.2; HSD22"
                     /note="hexamer: ATTAAA"
     polyA_site      596
                     /gene="SCP2D1"
                     /gene_synonym="C20orf79; dJ1068E13.2; HSD22"
                     /note="major polyA site"
ORIGIN      
        1 agatggcaag gtccagggga ctagcacagg aagatgtgga agagaagtga ccatcaaccc
       61 aagatcaaag cagaggatgg acctctggtg ggccagttcg aggttctggg ttcagttcca
      121 gaacctgcca tgccacatcc tctagagctg tcagaatttg agagcttccc agtgtttcag
      181 gacattaggc ttcacatcag ggaagtggga gctcaattgg tcaagaaagt caatgccgtc
      241 tttcagctgg acatcaccaa aaatgggaag accattttgc ggtggaccat tgatctgaag
      301 aatggttctg gggacatgta tccgggacct gccaggctcc cagcagacac tgtctttaca
      361 atcccggagt ctgtctttat ggagctggtt ttgggcaaaa tgaacccgca gaaggctttc
      421 cttgccggaa agttcaaagt gagtggcaag gttctgctta gctggaagct ggaaagggtt
      481 ttcaaagact gggctaaatt ttaagcatgc aaaaatacca aggaagaact tctcttcgat
      541 gataatgtcg agtggaaatc atgcttaatc tgaagattaa agtaaaaagt atccaa
//
