LOCUS       XM_047445395            4387 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens sodium voltage-gated channel alpha subunit
            3 (SCN3A), transcript variant X7, mRNA.
ACCESSION   XM_047445395
VERSION     XM_047445395.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4387
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..4387
                     /gene="SCN3A"
                     /gene_synonym="DEE62; EIEE62; FFEVF4; NAC3; Nav1.3"
                     /note="sodium voltage-gated channel alpha subunit 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 1 EST, 17 long SRA reads, 16
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 1 sample with
                     support for all annotated introns"
                     /db_xref="GeneID:6328"
                     /db_xref="HGNC:HGNC:10590"
                     /db_xref="MIM:182391"
     CDS             476..4249
                     /gene="SCN3A"
                     /gene_synonym="DEE62; EIEE62; FFEVF4; NAC3; Nav1.3"
                     /codon_start=1
                     /product="sodium channel protein type 3 subunit alpha
                     isoform X7"
                     /protein_id="XP_047301351.1"
                     /db_xref="GeneID:6328"
                     /db_xref="HGNC:HGNC:10590"
                     /db_xref="MIM:182391"
                     /translation="MAQALLVPPGPESFRLFTRESLAAIEKRAAEEKAKKPKKEQDND
                     DENKPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVMNKGKAIFRF
                     SATSALYILTPLNPVRKIAIKILVHSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYT
                     FTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTF
                     RVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNK
                     CLQWPPSDSAFETNTTSYFNGTMDSNGTFVNVTMSTFNWKDYIGDDSHFYVLDGQKDP
                     LLCGNGSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDYWENLYQLT
                     LRAAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLE
                     QLKKQQEEAQAVAAASAASRDFSGIGGLGELLESSSEASKLSSKSAKEWRNRRKKRRQ
                     REHLEGNNKGERDSFPKSESEDSVKRSSFLFSMDGNRLTSDKKFCSPHQSLLSIRGSL
                     FSPRRNSKTSIFSFRGRAKDVGSENDFADDEHSTFEDSESRRDSLFVPHRHGERRNSN
                     GTTTETEVRKRRLSSYQISMEMLEDSSGRQRAVSIASILTNTMEELEESRQKCPPCWY
                     RFANVFLIWDCCDAWLKVKHLVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFS
                     SVLTVGNLVFTGIFTAEMVLKIIAMDPYYYFQEGWNIFDGIIVSLSLMELGLSNVEGL
                     SVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFG
                     KSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIV
                     FMLVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDYVKNK
                     MRECFQKAFFRKPKVIEIHEGNKIDSCMSNNTGIEISKELNYLRDGNGTTSGVGTGSS
                     VEKYVIDENDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESELEESKEKLNATS
                     SSEGSTVDVVLPREGEQAETEPEEDLKPEACFTEGCIKKFPFCQVSTEEGKGKIWWNL
                     RKTCYSIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFIL
                     EMLLKWVAYGFQTYFTNAWCWLDFLIVDARCHLQPFCLSPLTTNQSASSSPFY"
     polyA_site      4387
                     /gene="SCN3A"
                     /gene_synonym="DEE62; EIEE62; FFEVF4; NAC3; Nav1.3"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agaacaggaa gcggaggcat aagcagagag gattctggaa aggtctcttt gttttcttat
       61 ccacagagaa agaaagaaaa aaaattgtaa ctaatttgta aacctctgtg gtcaaaaaaa
      121 aaaaaaaaaa aaaaagctga acagctgcag aggaagacac gttataccct aaccatcttg
      181 gatgctgggc tttgttatgc tgtaattcat aaggctctgt tttatcagag attatggagc
      241 aagaaaactg aagccaagcc acatcaaggt ttgacaggga tgagatacct gtcaaggatt
      301 catagtagag tggcttactg ggaaaggagc aaagaatctc ttctagggat attgtaagaa
      361 taaatgagat aattcacaga agggacctgg agcttttccg gaaaaaggtg ctgtgactat
      421 ctaaggtaat tcgtatgcaa gaagctacac gtaattaaat gtgcaggatg aaaagatggc
      481 acaggcactg ttggtacccc caggacctga aagcttccgc ctttttacta gagaatctct
      541 tgctgctatc gaaaaacgtg ctgcagaaga gaaagccaag aagcccaaaa aggaacaaga
      601 taatgatgat gagaacaaac caaagccaaa tagtgacttg gaagctggaa agaaccttcc
      661 atttatttat ggagacattc ctccagagat ggtgtcagag cccctggagg acctggatcc
      721 ctactatatc aataagaaaa cttttatagt aatgaataaa ggaaaggcaa ttttccgatt
      781 cagtgccacc tctgccttgt atattttaac tccactaaac cctgttagga aaattgctat
      841 caagattttg gtacattctt tattcagcat gcttatcatg tgcactattt tgaccaactg
      901 tgtatttatg accttgagca accctcctga ctggacaaag aatgtagagt acacattcac
      961 tggaatctat acctttgagt cacttataaa aatcttggca agagggtttt gcttagaaga
     1021 ttttacgttt cttcgtgatc catggaactg gctggatttc agtgtcattg tgatggcata
     1081 tgtgacagag tttgtggacc tgggcaatgt ctcagcgttg agaacattca gagttctccg
     1141 agcactgaaa acaatttcag tcattccagg tttaaagacc attgtggggg ccctgatcca
     1201 gtcggtaaag aagctttctg atgtgatgat cctgactgtg ttctgtctga gcgtgtttgc
     1261 tctcattggg ctgcagctgt tcatgggcaa tctgaggaat aaatgtttgc agtggccccc
     1321 aagcgattct gcttttgaaa ccaacaccac ttcctacttt aatggcacaa tggattcaaa
     1381 tgggacattt gttaatgtaa caatgagcac atttaactgg aaggattaca ttggagatga
     1441 cagtcacttt tatgttttgg atgggcaaaa agacccttta ctctgtggaa atggctcaga
     1501 tgcaggccag tgtccagaag gatacatctg tgtgaaggct ggtcgaaacc ccaactatgg
     1561 ctacacaagc tttgacacct ttagctgggc tttcctgtct ctatttcgac tcatgactca
     1621 agactactgg gaaaatcttt accagttgac attacgtgct gctgggaaaa catacatgat
     1681 attttttgtc ctggtcattt tcttgggctc attttatttg gtgaatttga tcctggctgt
     1741 ggtggccatg gcctatgagg agcagaatca ggccaccttg gaagaagcag aacaaaaaga
     1801 ggccgaattt cagcagatgc tcgaacagct taaaaagcaa caggaagaag ctcaggcagt
     1861 tgcggcagca tcagctgctt caagagattt cagtggaata ggtgggttag gagagctgtt
     1921 ggaaagttct tcagaagcat caaagttgag ttccaaaagt gctaaagaat ggaggaaccg
     1981 aaggaagaaa agaagacaga gagagcacct tgaaggaaac aacaaaggag agagagacag
     2041 ctttcccaaa tccgaatctg aagacagcgt caaaagaagc agcttccttt tctccatgga
     2101 tggaaacaga ctgaccagtg acaaaaaatt ctgctcccct catcagtctc tcttgagtat
     2161 ccgtggctcc ctgttttccc caagacgcaa tagcaaaaca agcattttca gtttcagagg
     2221 tcgggcaaag gatgttggat ctgaaaatga ctttgctgat gatgaacaca gcacatttga
     2281 agacagcgaa agcaggagag actcactgtt tgtgccgcac agacatggag agcgacgcaa
     2341 cagtaacggc accaccacag aaacggaagt cagaaagaga aggttaagct cttaccagat
     2401 ttcaatggag atgctggagg attcctctgg aaggcaaaga gccgtgagca tagccagcat
     2461 tctgaccaac acaatggaag aacttgaaga atctagacag aaatgtccgc catgctggta
     2521 tagatttgcc aatgtgttct tgatctggga ctgctgtgat gcatggttaa aagtaaaaca
     2581 tcttgtgaat ttaattgtta tggatccatt tgttgatctt gccatcacta tttgcattgt
     2641 cttaaatacc ctctttatgg ccatggagca ctaccccatg actgagcaat tcagtagtgt
     2701 gttgactgta ggaaacctgg tctttactgg gattttcaca gcagaaatgg ttctcaagat
     2761 cattgccatg gatccttatt actatttcca agaaggctgg aatatctttg atggaattat
     2821 tgtcagcctc agtttaatgg agcttggtct gtcaaatgtg gagggattgt ctgtactgcg
     2881 atcattcaga ctgcttagag ttttcaagtt ggcaaaatcc tggcccacac taaatatgct
     2941 aattaagatc attggcaatt ctgtgggggc tctaggaaac ctcaccttgg tgttggccat
     3001 catcgtcttc atttttgctg tggtcggcat gcagctcttt ggtaagagct acaaagaatg
     3061 tgtctgcaag atcaatgatg actgtacgct cccacggtgg cacatgaacg acttcttcca
     3121 ctccttcctg attgtgttcc gcgtgctgtg tggagagtgg atagagacca tgtgggactg
     3181 tatggaggtc gctggccaaa ccatgtgcct tattgttttc atgttggtca tggtcattgg
     3241 aaaccttgtg gttctgaacc tctttctggc cttattgttg agttcattta gctcagacaa
     3301 ccttgctgct actgatgatg acaatgaaat gaataatctg cagattgcag taggaagaat
     3361 gcaaaaggga attgattatg tgaaaaataa gatgcgggag tgtttccaaa aagccttttt
     3421 tagaaagcca aaagttatag aaatccatga aggcaataag atagacagct gcatgtccaa
     3481 taatactgga attgaaataa gcaaagagct taattatctt agagatggga atggaaccac
     3541 cagtggtgta ggtactggaa gcagtgttga aaaatacgta atcgatgaaa atgattatat
     3601 gtcattcata aacaacccca gcctcaccgt cacagtgcca attgctgttg gagagtctga
     3661 ctttgaaaac ttaaatactg aagagttcag cagtgagtca gaactagaag aaagcaaaga
     3721 gaaattaaat gcaaccagct catctgaagg aagcacagtt gatgttgttc taccccgaga
     3781 aggtgaacaa gctgaaactg aacccgaaga agaccttaaa ccggaagctt gttttactga
     3841 aggatgtatt aaaaagtttc cattctgtca agtaagtaca gaagaaggca aagggaagat
     3901 ctggtggaat cttcgaaaaa cctgctacag tattgttgag cacaactggt ttgagacttt
     3961 cattgtgttc atgatccttc tcagtagtgg tgcattggcc tttgaagata tatacattga
     4021 acagcgaaag actatcaaaa ccatgctaga atatgctgac aaagtcttta cctatatatt
     4081 cattctggaa atgcttctca aatgggttgc ttatggattt caaacatatt tcactaatgc
     4141 ctggtgctgg ctagatttct tgatcgttga tgccagatgt catcttcagc ctttctgcct
     4201 ttcacccctc acaaccaatc aatcagcaag ttcttctcca ttttattgac taataaatga
     4261 gtggacagtc tcgcccctcc tcttcagcac atcaacacca ctgcaatcaa ctggaccaag
     4321 caatagctta ctaaatgttc ctgcctccag tcacaacctc tgcaaataaa tgttttcgga
     4381 agaccta
//
