LOCUS       NM_145651                435 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens secretoglobin family 1C member 1 (SCGB1C1), mRNA.
ACCESSION   NM_145651
VERSION     NM_145651.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Ozdas,S. and Ozdas,T.
  TITLE     Differentially expressed Secretoglobin 1C1 gene in nasal polyposis
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 64 (1), 97-102 (2018)
   PUBMED   29412801
  REMARK    GeneRIF: results suggested that promotor variations in the function
            of the Secretoglobin 1C1 gene can alter the gene expression biology
            in nasal polyposis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Ozdas,S., Izbirak,A., Ozdas,T., Ozcan,K.M., Erbek,S.S., Koseoglu,S.
            and Dere,H.
  TITLE     Single-Nucleotide Polymorphisms on the RYD5 Gene in Nasal Polyposis
  JOURNAL   DNA Cell Biol 34 (10), 633-642 (2015)
   PUBMED   26204469
  REMARK    GeneRIF: Ryd5 single nucleotide polymorphisms and increased risk of
            nasal polyposis with asthma and allergy
REFERENCE   3  (bases 1 to 435)
  AUTHORS   Shameer,K., Denny,J.C., Ding,K., Jouni,H., Crosslin,D.R., de
            Andrade,M., Chute,C.G., Peissig,P., Pacheco,J.A., Li,R.,
            Bastarache,L., Kho,A.N., Ritchie,M.D., Masys,D.R., Chisholm,R.L.,
            Larson,E.B., McCarty,C.A., Roden,D.M., Jarvik,G.P. and Kullo,I.J.
  TITLE     A genome- and phenome-wide association study to identify genetic
            variants influencing platelet count and volume and their
            pleiotropic effects
  JOURNAL   Hum Genet 133 (1), 95-109 (2014)
   PUBMED   24026423
REFERENCE   4  (bases 1 to 435)
  AUTHORS   Jackson,B.C., Thompson,D.C., Wright,M.W., McAndrews,M., Bernard,A.,
            Nebert,D.W. and Vasiliou,V.
  TITLE     Update of the human secretoglobin (SCGB) gene superfamily and an
            example of 'evolutionary bloom' of androgen-binding protein genes
            within the mouse Scgb gene superfamily
  JOURNAL   Hum Genomics 5 (6), 691-702 (2011)
   PUBMED   22155607
  REMARK    Review article
REFERENCE   5  (bases 1 to 435)
  AUTHORS   Reynolds,S.D., Reynolds,P.R., Pryhuber,G.S., Finder,J.D. and
            Stripp,B.R.
  TITLE     Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in
            mouse and human airways
  JOURNAL   Am J Respir Crit Care Med 166 (11), 1498-1509 (2002)
   PUBMED   12406855
REFERENCE   6  (bases 1 to 435)
  AUTHORS   Dear,T.N., Boehm,T., Keverne,E.B. and Rabbitts,T.H.
  TITLE     Novel genes for potential ligand-binding proteins in subregions of
            the olfactory mucosa
  JOURNAL   EMBO J 10 (10), 2813-2819 (1991)
   PUBMED   1915264
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC069287.7 and AY026938.1.
            
            On May 17, 2019 this sequence version replaced NM_145651.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX098294.1, HY228308.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000342878.3/ ENSP00000344545.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC069287.7         66409-66410         c
            3-228               AY026938.1         1-226
            229-231             AC069287.7         65623-65625         c
            232-433             AY026938.1         230-431
            434-435             AC069287.7         64913-64914         c
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..435
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /note="secretoglobin family 1C member 1"
                     /db_xref="GeneID:147199"
                     /db_xref="HGNC:HGNC:18394"
                     /db_xref="MIM:610176"
     exon            1..77
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..310
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /note="ligand binding protein RYD5; secretoglobin RYD5"
                     /codon_start=1
                     /product="secretoglobin family 1C member 1 precursor"
                     /protein_id="NP_663626.2"
                     /db_xref="CCDS:CCDS41581.1"
                     /db_xref="GeneID:147199"
                     /db_xref="HGNC:HGNC:18394"
                     /db_xref="MIM:610176"
                     /translation="MKGSRALLLVALTLFCICRMATGEDNDEFFMDFLQTLLVGTPEE
                     LYEGTLGKYNVNEDAKAAMTELKSCIDGLQPMHKAELVKLLVQVLGSQDGA"
     exon            78..277
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /inference="alignment:Splign:2.1.0"
     exon            278..435
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      418..423
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /note="hexamer: AATAAA"
     polyA_site      435
                     /gene="SCGB1C1"
                     /gene_synonym="RYD5"
                     /note="major polyA site"
ORIGIN      
        1 ggcagctcct gagactgctg gcatgaaggg gagccgtgcc ctcctgctgg tggccctcac
       61 cctgttctgc atctgccgga tggccacagg ggaggacaac gatgagtttt tcatggactt
      121 cctgcaaaca ctactggtgg ggaccccaga ggagctctat gaggggacct tgggcaagta
      181 caatgtcaac gaagatgcca aggcagcaat gactgaactc aagtcctgta tagatggcct
      241 gcagccaatg cacaaggcgg agctggtcaa gctgctggtg caagtgctgg gcagtcagga
      301 cggtgcctaa gtggacctca gacatggctc agccatagga cctgccacac aagcagccgt
      361 ggacacaacg cccactacca cctcccacat ggaaatgtat cctcaaaccg tttaatcaat
      421 aaagcctctt ccgca
//
