LOCUS       XM_047447737            5145 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SREBF chaperone (SCAP), transcript variant
            X9, mRNA.
ACCESSION   XM_047447737
VERSION     XM_047447737.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5145
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..5145
                     /gene="SCAP"
                     /note="SREBF chaperone; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 160 ESTs, 1028 long SRA
                     reads, 8 Proteins, and 85% coverage of the annotated
                     genomic feature by RNAseq alignments, including 19 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
     CDS             1136..4972
                     /gene="SCAP"
                     /codon_start=1
                     /product="sterol regulatory element-binding protein
                     cleavage-activating protein isoform X2"
                     /protein_id="XP_047303693.1"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
                     /translation="MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPL
                     LKLPLPGTGPVEFTTPVKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSV
                     FPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKL
                     RNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPG
                     KYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHF
                     KEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLC
                     TLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSI
                     MKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELA
                     DLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVY
                     FLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSG
                     MLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEEL
                     WRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPP
                     GPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
                     LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHV
                     CVWDAQTGDCLTRIPRPGQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHR
                     PRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCL
                     VQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSL
                     ELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDF
                     FSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAA
                     GRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDV
                     LTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGAS
                     LGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFG
                     SELSLVYVPSVLEKLD"
ORIGIN      
        1 acattgttat gcaaccatca tcactatcca tttccagaat gttttcatta ttctacatag
       61 aaactatcga tccaggagcc atatgtagaa agctgaaact ggatcccttc cttacacctt
      121 atacaaaaat caattcaaga tggattaaag acttaaatgt tagacctaaa accataaaaa
      181 ccctagaaga aaacctaggc aataccattc aggccatagg catgggcaag gacttcatga
      241 ctaaaacacc aaaagcaatg gcaacaaaag ccaaaattga caaatgggat ctaattaaac
      301 taaagagctt ctacacagca aaagaaacta ccatcagact gaacaggcaa cctacagagt
      361 gggagaaaat ttttacaatc tacccatctg acaaagggct aatatccaga atctacaaag
      421 aacttaaaca gatttacaag aaaaaaatca aacaacccta tcaaaaagtg ggtgaagcat
      481 atgaacagac acttctcaaa agaagacatt tatgcagcca acagacacat gaaaaaatgc
      541 ttgtcgtcac tggccatcag agaaatgcaa atcaaaacca caatgagata ccctcacacc
      601 agttagaatg gggatcatta aaaagtcagg aaacaacagg tgctggagag gatgtggaga
      661 aataggaacc cttttacact gttggtggga ctgtaaacta gttcaaccat tgtggaagac
      721 agtgtggcga ttcctcaagg atctagaact agaaatacca tttgacccag ccatcccatt
      781 actgggcata tacccaaagg attataaatc atgctgctat aaaggcacat gcacacgtat
      841 gtttattacg gcactattca caatagcaaa gacttggaac caacccaaat gtccatcaat
      901 gatagactgg attaagaaaa tgtggcacat atacaccatg gaatactatg cagccataaa
      961 aaaaggttag atgggtagtg ctgacatcat aacaaggttc aagaatgact catctcacat
     1021 gtgtgtgaaa cacccaggta cctgcacatg ttgttctttg tcagtgctgt caagtgtgtg
     1081 ccagggtgat ccatggtcac tttccgggat ggcagcaagg tgacttcggc tgaggatgac
     1141 cctgactgaa aggctgcgtg agaagatatc tcgggccttc tacaaccatg ggctcctctg
     1201 tgcatcctat cccatcccca tcatcctctt cacagggttc tgcatcttag cctgctgcta
     1261 cccactgctg aaactcccct tgccaggaac aggacctgtg gaattcacca cccctgtgaa
     1321 ggattactcg cccccacctg tggactctga ccgcaaacaa ggagagccta ctgagcagcc
     1381 tgagtggtat gtgggtgccc cggtggctta tgtccagcag atatttgtga agtcctcagt
     1441 gtttccctgg cacaagaacc tcctggcagt agatgtattt cgttcacctt tgtcccgggc
     1501 attccaactg gtggaggaga tccggaacca cgtgctgaga gacagctctg ggatcaggag
     1561 cttggaggag ttgtgtctgc aagtgaccga cctgctgcca ggccttagga agctcaggaa
     1621 cctactccct gagcatggat gcctgctgct gtcccctggg aacttctggc agaatgactg
     1681 ggaacgcttc catgctgatc ctgacatcat tgggaccatc caccagcacg agcctaaaac
     1741 cctgcagact tcagccacac tcaaagactt gttatttggt gttcctggga agtacagcgg
     1801 ggtgagcctc tacaccagga agaggatggt ctcctacacc atcaccctgg tcttccagca
     1861 ctaccatgcc aagttcctgg gcagcctgcg tgcccgcctg atgcttctgc accccagccc
     1921 caactgcagc cttcgggcgg agagcctggt ccacgtgcac ttcaaggagg agattggtgt
     1981 cgctgagctc atcccccttg tgaccaccta catcatcttg tttgcctaca tctacttctc
     2041 cacgcggaag atcgacatgg tcaagtccaa gtgggggctg gccctggctg ccgtggtcac
     2101 agtgctcagc tcgctgctca tgtctgtggg actctgcaca ctcttcggcc tgacgcccac
     2161 cctcaatggc ggcgagattt tcccctacct tgtggtggtt attgggttag agaatgtgtt
     2221 ggtgctcacc aagtctgtgg tctcaacccc ggtagacctg gaggtgaagc tgcggatcgc
     2281 ccaaggccta agcagcgaga gctggtccat catgaagaac atggccacgg agctgggcat
     2341 catcctcatc ggctacttca ccctagtgcc cgccatccag gagttctgtc tctttgctgt
     2401 cgtggggctg gtgtctgact tcttccttca gatgctgttt ttcaccactg tcctgtccat
     2461 tgacattcgc cggatggagc tagcagacct gaacaagcga ctgccccctg aggcctgcct
     2521 gccctcagcc aagccagtgg gacagccaac gcgctacgag cggcagctgg ctgtgaggcc
     2581 gtccacaccc cacaccatca cgttgcagcc gtcttccttc cgaaacctgc ggctccccaa
     2641 gaggctgcgt gttgtctact tcctggcccg cacccgcctg gcacagcgcc tcatcatggc
     2701 tggcaccgtt gtctggattg gcatcctggt atacacagac ccagcagggc tgcgcaacta
     2761 cctcgctgcc caggtgacgg aacagagccc attgggtgag ggagccctgg ctcccatgcc
     2821 cgtgcctagt ggcatgctgc cccccagcca cccggaccct gccttctcca tcttcccacc
     2881 tgatgcccct aagctacctg agaaccagac gtcgccaggc gagtcacctg agcgtggagg
     2941 tccagcagag gttgtccatg acagcccagt cccagaggta acctgggggc ctgaggatga
     3001 ggaactttgg aggaaattgt ccttccgcca ctggccgacg ctcttcagct attacaacat
     3061 cacactggcc aagaggtaca tcagcctgct gcccgtcatc ccagtcacgc tccgcctgaa
     3121 cccgagggag gctctggagg gccggcaccc tcaggacggc cgcagtgcct ggcccccacc
     3181 ggggcccata cctgctgggc actgggaagc aggacccaag ggcccaggtg gggtgcaggc
     3241 ccatggagac gtcacgctgt acaaggtggc ggcgctgggc ctggccaccg gcatcgtctt
     3301 ggtgctgctg ctgctctgcc tctaccgcgt gctatgcccg cgcaactacg ggcagctggg
     3361 tggtgggccc gggcggcgga ggcgcgggga gctgccctgc gacgactacg gctatgcgcc
     3421 acccgagacg gagatcgtgc cgcttgtgct gcgcggccac ctcatggaca tcgagtgcct
     3481 ggccagcgac ggcatgctgc tggtgagctg ctgcctggca ggccacgtct gcgtgtggga
     3541 cgcgcagacc ggggattgcc taacgcgcat tccgcgccca gggcagcgcc gggacagtgg
     3601 cgtgggcagc gggcttgagg ctcaggagag ctgggaacga ctttcagatg gtgggaaggc
     3661 tggtccagag gagcctgggg acagccctcc cctgagacac cgcccccggg gccctccgcc
     3721 gccttccctc ttcggggacc agcctgacct cacctgctta attgacacca acttttcagc
     3781 gcagcctcgg tcctcacagc ccactcagcc cgagccccgg caccgggcgg tctgtggccg
     3841 ctctcgggac tccccaggct atgacttcag ctgcctggtg cagcgggtgt accaggagga
     3901 ggggctggcg gccgtctgca caccagccct gcgcccaccc tcgcctgggc cggtgctgtc
     3961 ccaggcccct gaggacgagg gtggctcccc cgagaaaggc tccccttccc tcgcctgggc
     4021 ccccagtgcc gagggttcca tctggagctt ggagctgcag ggcaacctca tcgtggtggg
     4081 gcggagcagc ggccggctgg aggtgtggga cgccattgaa ggggtgctgt gctgcagcag
     4141 cgaggaggtc tcctcaggca ttaccgctct ggtgttcttg gacaaaagga ttgtggctgc
     4201 acggctcaac ggttcccttg atttcttctc cttggagacc cacactgccc tcagccccct
     4261 gcagtttaga gggaccccag ggcggggcag ttcccctgcc tctccagtgt acagcagcag
     4321 cgacacagtg gcctgtcacc tgacccacac agtgccctgt gcacaccaaa aacccatcac
     4381 agccctgaaa gccgctgctg ggcgcttggt gactgggagc caagaccaca cactgagagt
     4441 gttccgtctg gaggactcgt gctgcctctt cacccttcag ggccactcag gggccatcac
     4501 gaccgtgtac attgaccaga ccatggtgct ggccagtgga ggacaagatg gggccatctg
     4561 cctgtgggat gtactgactg gcagccgggt cagccatgtg tttgctcacc gtggggatgt
     4621 cacctccctt acctgtacca cctcctgtgt catcagcagt ggcctggatg acctcatcag
     4681 catctgggac cgcagcacag gcatcaagtt ctactccatt cagcaggacc tgggctgtgg
     4741 tgcaagcttg ggtgtcatct cagacaacct gctggtgact ggcggccagg gctgtgtctc
     4801 cttttgggac ctaaactacg gggacctgtt acagacagtc tacctgggga agaacagtga
     4861 ggcccagcct gcccgccaga tcctggtgct ggacaacgct gccattgtct gcaactttgg
     4921 cagtgagctc agcctggtgt atgtgccctc tgtgctggag aagctggact gagcgcaggg
     4981 cctccttgcc caggcaggag gctggggtgc tgtgtggggg ccaatgcact gaacctggac
     5041 ttgggggaaa gagccgagta tcttccagcc gctgcctcct gactgtaata atattaaact
     5101 tttttaaaaa accatatcat catctgtcag gcactttggg agcta
//
