LOCUS       XM_047447736            4306 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SREBF chaperone (SCAP), transcript variant
            X7, mRNA.
ACCESSION   XM_047447736
VERSION     XM_047447736.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4306
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4306
                     /gene="SCAP"
                     /note="SREBF chaperone; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 150 ESTs, 485 long SRA
                     reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 18 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
     CDS             294..4133
                     /gene="SCAP"
                     /codon_start=1
                     /product="sterol regulatory element-binding protein
                     cleavage-activating protein isoform X1"
                     /protein_id="XP_047303692.1"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
                     /translation="MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPL
                     LKLPLPGTGPVEFTTPVKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSV
                     FPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKL
                     RNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPG
                     KYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHF
                     KEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLC
                     TLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSI
                     MKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELA
                     DLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVY
                     FLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSG
                     MLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEEL
                     WRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPP
                     GPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
                     LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHV
                     CVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRH
                     RPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSC
                     LVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWS
                     LELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLD
                     FFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAA
                     AGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWD
                     VLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGA
                     SLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
                     GSELSLVYVPSVLEKLD"
ORIGIN      
        1 gcaataggca ttccttttgg cttttgagtt ggctgtggtg tgactccttt tgcttcttgt
       61 ttctgatctt gacacttatg aggagtcatc tttgagtctg ggttttcatc agtgagtaca
      121 gtcaagccaa gaaatgtgtc tgggcaggtt ccctctagca cagaccgaag aaaacagcaa
      181 catggaacaa gagaagtacc tgcacatgtt gttctttgtc agtgctgtca agtgtgtgcc
      241 agggtgatcc atggtcactt tccgggatgg cagcaaggtg acttcggctg aggatgaccc
      301 tgactgaaag gctgcgtgag aagatatctc gggccttcta caaccatggg ctcctctgtg
      361 catcctatcc catccccatc atcctcttca cagggttctg catcttagcc tgctgctacc
      421 cactgctgaa actccccttg ccaggaacag gacctgtgga attcaccacc cctgtgaagg
      481 attactcgcc cccacctgtg gactctgacc gcaaacaagg agagcctact gagcagcctg
      541 agtggtatgt gggtgccccg gtggcttatg tccagcagat atttgtgaag tcctcagtgt
      601 ttccctggca caagaacctc ctggcagtag atgtatttcg ttcacctttg tcccgggcat
      661 tccaactggt ggaggagatc cggaaccacg tgctgagaga cagctctggg atcaggagct
      721 tggaggagtt gtgtctgcaa gtgaccgacc tgctgccagg ccttaggaag ctcaggaacc
      781 tactccctga gcatggatgc ctgctgctgt cccctgggaa cttctggcag aatgactggg
      841 aacgcttcca tgctgatcct gacatcattg ggaccatcca ccagcacgag cctaaaaccc
      901 tgcagacttc agccacactc aaagacttgt tatttggtgt tcctgggaag tacagcgggg
      961 tgagcctcta caccaggaag aggatggtct cctacaccat caccctggtc ttccagcact
     1021 accatgccaa gttcctgggc agcctgcgtg cccgcctgat gcttctgcac cccagcccca
     1081 actgcagcct tcgggcggag agcctggtcc acgtgcactt caaggaggag attggtgtcg
     1141 ctgagctcat cccccttgtg accacctaca tcatcttgtt tgcctacatc tacttctcca
     1201 cgcggaagat cgacatggtc aagtccaagt gggggctggc cctggctgcc gtggtcacag
     1261 tgctcagctc gctgctcatg tctgtgggac tctgcacact cttcggcctg acgcccaccc
     1321 tcaatggcgg cgagattttc ccctaccttg tggtggttat tgggttagag aatgtgttgg
     1381 tgctcaccaa gtctgtggtc tcaaccccgg tagacctgga ggtgaagctg cggatcgccc
     1441 aaggcctaag cagcgagagc tggtccatca tgaagaacat ggccacggag ctgggcatca
     1501 tcctcatcgg ctacttcacc ctagtgcccg ccatccagga gttctgtctc tttgctgtcg
     1561 tggggctggt gtctgacttc ttccttcaga tgctgttttt caccactgtc ctgtccattg
     1621 acattcgccg gatggagcta gcagacctga acaagcgact gccccctgag gcctgcctgc
     1681 cctcagccaa gccagtggga cagccaacgc gctacgagcg gcagctggct gtgaggccgt
     1741 ccacacccca caccatcacg ttgcagccgt cttccttccg aaacctgcgg ctccccaaga
     1801 ggctgcgtgt tgtctacttc ctggcccgca cccgcctggc acagcgcctc atcatggctg
     1861 gcaccgttgt ctggattggc atcctggtat acacagaccc agcagggctg cgcaactacc
     1921 tcgctgccca ggtgacggaa cagagcccat tgggtgaggg agccctggct cccatgcccg
     1981 tgcctagtgg catgctgccc cccagccacc cggaccctgc cttctccatc ttcccacctg
     2041 atgcccctaa gctacctgag aaccagacgt cgccaggcga gtcacctgag cgtggaggtc
     2101 cagcagaggt tgtccatgac agcccagtcc cagaggtaac ctgggggcct gaggatgagg
     2161 aactttggag gaaattgtcc ttccgccact ggccgacgct cttcagctat tacaacatca
     2221 cactggccaa gaggtacatc agcctgctgc ccgtcatccc agtcacgctc cgcctgaacc
     2281 cgagggaggc tctggagggc cggcaccctc aggacggccg cagtgcctgg cccccaccgg
     2341 ggcccatacc tgctgggcac tgggaagcag gacccaaggg cccaggtggg gtgcaggccc
     2401 atggagacgt cacgctgtac aaggtggcgg cgctgggcct ggccaccggc atcgtcttgg
     2461 tgctgctgct gctctgcctc taccgcgtgc tatgcccgcg caactacggg cagctgggtg
     2521 gtgggcccgg gcggcggagg cgcggggagc tgccctgcga cgactacggc tatgcgccac
     2581 ccgagacgga gatcgtgccg cttgtgctgc gcggccacct catggacatc gagtgcctgg
     2641 ccagcgacgg catgctgctg gtgagctgct gcctggcagg ccacgtctgc gtgtgggacg
     2701 cgcagaccgg ggattgccta acgcgcattc cgcgcccagg caggcagcgc cgggacagtg
     2761 gcgtgggcag cgggcttgag gctcaggaga gctgggaacg actttcagat ggtgggaagg
     2821 ctggtccaga ggagcctggg gacagccctc ccctgagaca ccgcccccgg ggccctccgc
     2881 cgccttccct cttcggggac cagcctgacc tcacctgctt aattgacacc aacttttcag
     2941 cgcagcctcg gtcctcacag cccactcagc ccgagccccg gcaccgggcg gtctgtggcc
     3001 gctctcggga ctccccaggc tatgacttca gctgcctggt gcagcgggtg taccaggagg
     3061 aggggctggc ggccgtctgc acaccagccc tgcgcccacc ctcgcctggg ccggtgctgt
     3121 cccaggcccc tgaggacgag ggtggctccc ccgagaaagg ctccccttcc ctcgcctggg
     3181 cccccagtgc cgagggttcc atctggagct tggagctgca gggcaacctc atcgtggtgg
     3241 ggcggagcag cggccggctg gaggtgtggg acgccattga aggggtgctg tgctgcagca
     3301 gcgaggaggt ctcctcaggc attaccgctc tggtgttctt ggacaaaagg attgtggctg
     3361 cacggctcaa cggttccctt gatttcttct ccttggagac ccacactgcc ctcagccccc
     3421 tgcagtttag agggacccca gggcggggca gttcccctgc ctctccagtg tacagcagca
     3481 gcgacacagt ggcctgtcac ctgacccaca cagtgccctg tgcacaccaa aaacccatca
     3541 cagccctgaa agccgctgct gggcgcttgg tgactgggag ccaagaccac acactgagag
     3601 tgttccgtct ggaggactcg tgctgcctct tcacccttca gggccactca ggggccatca
     3661 cgaccgtgta cattgaccag accatggtgc tggccagtgg aggacaagat ggggccatct
     3721 gcctgtggga tgtactgact ggcagccggg tcagccatgt gtttgctcac cgtggggatg
     3781 tcacctccct tacctgtacc acctcctgtg tcatcagcag tggcctggat gacctcatca
     3841 gcatctggga ccgcagcaca ggcatcaagt tctactccat tcagcaggac ctgggctgtg
     3901 gtgcaagctt gggtgtcatc tcagacaacc tgctggtgac tggcggccag ggctgtgtct
     3961 ccttttggga cctaaactac ggggacctgt tacagacagt ctacctgggg aagaacagtg
     4021 aggcccagcc tgcccgccag atcctggtgc tggacaacgc tgccattgtc tgcaactttg
     4081 gcagtgagct cagcctggtg tatgtgccct ctgtgctgga gaagctggac tgagcgcagg
     4141 gcctccttgc ccaggcagga ggctggggtg ctgtgtgggg gccaatgcac tgaacctgga
     4201 cttgggggaa agagccgagt atcttccagc cgctgcctcc tgactgtaat aatattaaac
     4261 ttttttaaaa aaccatatca tcatctgtca ggcactttgg gagcta
//
