LOCUS       XM_047447735            4194 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SREBF chaperone (SCAP), transcript variant
            X6, mRNA.
ACCESSION   XM_047447735
VERSION     XM_047447735.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4194
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4194
                     /gene="SCAP"
                     /note="SREBF chaperone; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 152 ESTs, 485
                     long SRA reads, 3 Proteins, and 98% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     94 samples with support for all annotated introns"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
     CDS             182..4021
                     /gene="SCAP"
                     /codon_start=1
                     /product="sterol regulatory element-binding protein
                     cleavage-activating protein isoform X1"
                     /protein_id="XP_047303691.1"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
                     /translation="MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPL
                     LKLPLPGTGPVEFTTPVKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSV
                     FPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKL
                     RNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPG
                     KYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHF
                     KEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLC
                     TLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSI
                     MKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELA
                     DLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVY
                     FLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSG
                     MLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEEL
                     WRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPP
                     GPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
                     LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHV
                     CVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRH
                     RPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSC
                     LVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWS
                     LELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLD
                     FFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAA
                     AGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWD
                     VLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGA
                     SLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
                     GSELSLVYVPSVLEKLD"
ORIGIN      
        1 acataactat cgcctccctc cagcagccct agtgtgcaga gccaagtact ctttgttaac
       61 tggcttttct cccttcttac caggtacctg cacatgttgt tctttgtcag tgctgtcaag
      121 tgtgtgccag ggtgatccat ggtcactttc cgggatggca gcaaggtgac ttcggctgag
      181 gatgaccctg actgaaaggc tgcgtgagaa gatatctcgg gccttctaca accatgggct
      241 cctctgtgca tcctatccca tccccatcat cctcttcaca gggttctgca tcttagcctg
      301 ctgctaccca ctgctgaaac tccccttgcc aggaacagga cctgtggaat tcaccacccc
      361 tgtgaaggat tactcgcccc cacctgtgga ctctgaccgc aaacaaggag agcctactga
      421 gcagcctgag tggtatgtgg gtgccccggt ggcttatgtc cagcagatat ttgtgaagtc
      481 ctcagtgttt ccctggcaca agaacctcct ggcagtagat gtatttcgtt cacctttgtc
      541 ccgggcattc caactggtgg aggagatccg gaaccacgtg ctgagagaca gctctgggat
      601 caggagcttg gaggagttgt gtctgcaagt gaccgacctg ctgccaggcc ttaggaagct
      661 caggaaccta ctccctgagc atggatgcct gctgctgtcc cctgggaact tctggcagaa
      721 tgactgggaa cgcttccatg ctgatcctga catcattggg accatccacc agcacgagcc
      781 taaaaccctg cagacttcag ccacactcaa agacttgtta tttggtgttc ctgggaagta
      841 cagcggggtg agcctctaca ccaggaagag gatggtctcc tacaccatca ccctggtctt
      901 ccagcactac catgccaagt tcctgggcag cctgcgtgcc cgcctgatgc ttctgcaccc
      961 cagccccaac tgcagccttc gggcggagag cctggtccac gtgcacttca aggaggagat
     1021 tggtgtcgct gagctcatcc cccttgtgac cacctacatc atcttgtttg cctacatcta
     1081 cttctccacg cggaagatcg acatggtcaa gtccaagtgg gggctggccc tggctgccgt
     1141 ggtcacagtg ctcagctcgc tgctcatgtc tgtgggactc tgcacactct tcggcctgac
     1201 gcccaccctc aatggcggcg agattttccc ctaccttgtg gtggttattg ggttagagaa
     1261 tgtgttggtg ctcaccaagt ctgtggtctc aaccccggta gacctggagg tgaagctgcg
     1321 gatcgcccaa ggcctaagca gcgagagctg gtccatcatg aagaacatgg ccacggagct
     1381 gggcatcatc ctcatcggct acttcaccct agtgcccgcc atccaggagt tctgtctctt
     1441 tgctgtcgtg gggctggtgt ctgacttctt ccttcagatg ctgtttttca ccactgtcct
     1501 gtccattgac attcgccgga tggagctagc agacctgaac aagcgactgc cccctgaggc
     1561 ctgcctgccc tcagccaagc cagtgggaca gccaacgcgc tacgagcggc agctggctgt
     1621 gaggccgtcc acaccccaca ccatcacgtt gcagccgtct tccttccgaa acctgcggct
     1681 ccccaagagg ctgcgtgttg tctacttcct ggcccgcacc cgcctggcac agcgcctcat
     1741 catggctggc accgttgtct ggattggcat cctggtatac acagacccag cagggctgcg
     1801 caactacctc gctgcccagg tgacggaaca gagcccattg ggtgagggag ccctggctcc
     1861 catgcccgtg cctagtggca tgctgccccc cagccacccg gaccctgcct tctccatctt
     1921 cccacctgat gcccctaagc tacctgagaa ccagacgtcg ccaggcgagt cacctgagcg
     1981 tggaggtcca gcagaggttg tccatgacag cccagtccca gaggtaacct gggggcctga
     2041 ggatgaggaa ctttggagga aattgtcctt ccgccactgg ccgacgctct tcagctatta
     2101 caacatcaca ctggccaaga ggtacatcag cctgctgccc gtcatcccag tcacgctccg
     2161 cctgaacccg agggaggctc tggagggccg gcaccctcag gacggccgca gtgcctggcc
     2221 cccaccgggg cccatacctg ctgggcactg ggaagcagga cccaagggcc caggtggggt
     2281 gcaggcccat ggagacgtca cgctgtacaa ggtggcggcg ctgggcctgg ccaccggcat
     2341 cgtcttggtg ctgctgctgc tctgcctcta ccgcgtgcta tgcccgcgca actacgggca
     2401 gctgggtggt gggcccgggc ggcggaggcg cggggagctg ccctgcgacg actacggcta
     2461 tgcgccaccc gagacggaga tcgtgccgct tgtgctgcgc ggccacctca tggacatcga
     2521 gtgcctggcc agcgacggca tgctgctggt gagctgctgc ctggcaggcc acgtctgcgt
     2581 gtgggacgcg cagaccgggg attgcctaac gcgcattccg cgcccaggca ggcagcgccg
     2641 ggacagtggc gtgggcagcg ggcttgaggc tcaggagagc tgggaacgac tttcagatgg
     2701 tgggaaggct ggtccagagg agcctgggga cagccctccc ctgagacacc gcccccgggg
     2761 ccctccgccg ccttccctct tcggggacca gcctgacctc acctgcttaa ttgacaccaa
     2821 cttttcagcg cagcctcggt cctcacagcc cactcagccc gagccccggc accgggcggt
     2881 ctgtggccgc tctcgggact ccccaggcta tgacttcagc tgcctggtgc agcgggtgta
     2941 ccaggaggag gggctggcgg ccgtctgcac accagccctg cgcccaccct cgcctgggcc
     3001 ggtgctgtcc caggcccctg aggacgaggg tggctccccc gagaaaggct ccccttccct
     3061 cgcctgggcc cccagtgccg agggttccat ctggagcttg gagctgcagg gcaacctcat
     3121 cgtggtgggg cggagcagcg gccggctgga ggtgtgggac gccattgaag gggtgctgtg
     3181 ctgcagcagc gaggaggtct cctcaggcat taccgctctg gtgttcttgg acaaaaggat
     3241 tgtggctgca cggctcaacg gttcccttga tttcttctcc ttggagaccc acactgccct
     3301 cagccccctg cagtttagag ggaccccagg gcggggcagt tcccctgcct ctccagtgta
     3361 cagcagcagc gacacagtgg cctgtcacct gacccacaca gtgccctgtg cacaccaaaa
     3421 acccatcaca gccctgaaag ccgctgctgg gcgcttggtg actgggagcc aagaccacac
     3481 actgagagtg ttccgtctgg aggactcgtg ctgcctcttc acccttcagg gccactcagg
     3541 ggccatcacg accgtgtaca ttgaccagac catggtgctg gccagtggag gacaagatgg
     3601 ggccatctgc ctgtgggatg tactgactgg cagccgggtc agccatgtgt ttgctcaccg
     3661 tggggatgtc acctccctta cctgtaccac ctcctgtgtc atcagcagtg gcctggatga
     3721 cctcatcagc atctgggacc gcagcacagg catcaagttc tactccattc agcaggacct
     3781 gggctgtggt gcaagcttgg gtgtcatctc agacaacctg ctggtgactg gcggccaggg
     3841 ctgtgtctcc ttttgggacc taaactacgg ggacctgtta cagacagtct acctggggaa
     3901 gaacagtgag gcccagcctg cccgccagat cctggtgctg gacaacgctg ccattgtctg
     3961 caactttggc agtgagctca gcctggtgta tgtgccctct gtgctggaga agctggactg
     4021 agcgcagggc ctccttgccc aggcaggagg ctggggtgct gtgtgggggc caatgcactg
     4081 aacctggact tgggggaaag agccgagtat cttccagccg ctgcctcctg actgtaataa
     4141 tattaaactt ttttaaaaaa ccatatcatc atctgtcagg cactttggga gcta
//
