LOCUS       XM_047447734            4179 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SREBF chaperone (SCAP), transcript variant
            X4, mRNA.
ACCESSION   XM_047447734
VERSION     XM_047447734.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4179
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4179
                     /gene="SCAP"
                     /note="SREBF chaperone; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 150 ESTs, 485 long SRA
                     reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
     CDS             167..4006
                     /gene="SCAP"
                     /codon_start=1
                     /product="sterol regulatory element-binding protein
                     cleavage-activating protein isoform X1"
                     /protein_id="XP_047303690.1"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
                     /translation="MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPL
                     LKLPLPGTGPVEFTTPVKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSV
                     FPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKL
                     RNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPG
                     KYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHF
                     KEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLC
                     TLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSI
                     MKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELA
                     DLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVY
                     FLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSG
                     MLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEEL
                     WRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPP
                     GPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
                     LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHV
                     CVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRH
                     RPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSC
                     LVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWS
                     LELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLD
                     FFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAA
                     AGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWD
                     VLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGA
                     SLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
                     GSELSLVYVPSVLEKLD"
ORIGIN      
        1 caaaggcttt gaggaccaaa ctgtggagta cattactgct caagtagttc tgcactggcc
       61 cctggacggt acctgcacat gttgttcttt gtcagtgctg tcaagtgtgt gccagggtga
      121 tccatggtca ctttccggga tggcagcaag gtgacttcgg ctgaggatga ccctgactga
      181 aaggctgcgt gagaagatat ctcgggcctt ctacaaccat gggctcctct gtgcatccta
      241 tcccatcccc atcatcctct tcacagggtt ctgcatctta gcctgctgct acccactgct
      301 gaaactcccc ttgccaggaa caggacctgt ggaattcacc acccctgtga aggattactc
      361 gcccccacct gtggactctg accgcaaaca aggagagcct actgagcagc ctgagtggta
      421 tgtgggtgcc ccggtggctt atgtccagca gatatttgtg aagtcctcag tgtttccctg
      481 gcacaagaac ctcctggcag tagatgtatt tcgttcacct ttgtcccggg cattccaact
      541 ggtggaggag atccggaacc acgtgctgag agacagctct gggatcagga gcttggagga
      601 gttgtgtctg caagtgaccg acctgctgcc aggccttagg aagctcagga acctactccc
      661 tgagcatgga tgcctgctgc tgtcccctgg gaacttctgg cagaatgact gggaacgctt
      721 ccatgctgat cctgacatca ttgggaccat ccaccagcac gagcctaaaa ccctgcagac
      781 ttcagccaca ctcaaagact tgttatttgg tgttcctggg aagtacagcg gggtgagcct
      841 ctacaccagg aagaggatgg tctcctacac catcaccctg gtcttccagc actaccatgc
      901 caagttcctg ggcagcctgc gtgcccgcct gatgcttctg caccccagcc ccaactgcag
      961 ccttcgggcg gagagcctgg tccacgtgca cttcaaggag gagattggtg tcgctgagct
     1021 catccccctt gtgaccacct acatcatctt gtttgcctac atctacttct ccacgcggaa
     1081 gatcgacatg gtcaagtcca agtgggggct ggccctggct gccgtggtca cagtgctcag
     1141 ctcgctgctc atgtctgtgg gactctgcac actcttcggc ctgacgccca ccctcaatgg
     1201 cggcgagatt ttcccctacc ttgtggtggt tattgggtta gagaatgtgt tggtgctcac
     1261 caagtctgtg gtctcaaccc cggtagacct ggaggtgaag ctgcggatcg cccaaggcct
     1321 aagcagcgag agctggtcca tcatgaagaa catggccacg gagctgggca tcatcctcat
     1381 cggctacttc accctagtgc ccgccatcca ggagttctgt ctctttgctg tcgtggggct
     1441 ggtgtctgac ttcttccttc agatgctgtt tttcaccact gtcctgtcca ttgacattcg
     1501 ccggatggag ctagcagacc tgaacaagcg actgccccct gaggcctgcc tgccctcagc
     1561 caagccagtg ggacagccaa cgcgctacga gcggcagctg gctgtgaggc cgtccacacc
     1621 ccacaccatc acgttgcagc cgtcttcctt ccgaaacctg cggctcccca agaggctgcg
     1681 tgttgtctac ttcctggccc gcacccgcct ggcacagcgc ctcatcatgg ctggcaccgt
     1741 tgtctggatt ggcatcctgg tatacacaga cccagcaggg ctgcgcaact acctcgctgc
     1801 ccaggtgacg gaacagagcc cattgggtga gggagccctg gctcccatgc ccgtgcctag
     1861 tggcatgctg ccccccagcc acccggaccc tgccttctcc atcttcccac ctgatgcccc
     1921 taagctacct gagaaccaga cgtcgccagg cgagtcacct gagcgtggag gtccagcaga
     1981 ggttgtccat gacagcccag tcccagaggt aacctggggg cctgaggatg aggaactttg
     2041 gaggaaattg tccttccgcc actggccgac gctcttcagc tattacaaca tcacactggc
     2101 caagaggtac atcagcctgc tgcccgtcat cccagtcacg ctccgcctga acccgaggga
     2161 ggctctggag ggccggcacc ctcaggacgg ccgcagtgcc tggcccccac cggggcccat
     2221 acctgctggg cactgggaag caggacccaa gggcccaggt ggggtgcagg cccatggaga
     2281 cgtcacgctg tacaaggtgg cggcgctggg cctggccacc ggcatcgtct tggtgctgct
     2341 gctgctctgc ctctaccgcg tgctatgccc gcgcaactac gggcagctgg gtggtgggcc
     2401 cgggcggcgg aggcgcgggg agctgccctg cgacgactac ggctatgcgc cacccgagac
     2461 ggagatcgtg ccgcttgtgc tgcgcggcca cctcatggac atcgagtgcc tggccagcga
     2521 cggcatgctg ctggtgagct gctgcctggc aggccacgtc tgcgtgtggg acgcgcagac
     2581 cggggattgc ctaacgcgca ttccgcgccc aggcaggcag cgccgggaca gtggcgtggg
     2641 cagcgggctt gaggctcagg agagctggga acgactttca gatggtggga aggctggtcc
     2701 agaggagcct ggggacagcc ctcccctgag acaccgcccc cggggccctc cgccgccttc
     2761 cctcttcggg gaccagcctg acctcacctg cttaattgac accaactttt cagcgcagcc
     2821 tcggtcctca cagcccactc agcccgagcc ccggcaccgg gcggtctgtg gccgctctcg
     2881 ggactcccca ggctatgact tcagctgcct ggtgcagcgg gtgtaccagg aggaggggct
     2941 ggcggccgtc tgcacaccag ccctgcgccc accctcgcct gggccggtgc tgtcccaggc
     3001 ccctgaggac gagggtggct cccccgagaa aggctcccct tccctcgcct gggcccccag
     3061 tgccgagggt tccatctgga gcttggagct gcagggcaac ctcatcgtgg tggggcggag
     3121 cagcggccgg ctggaggtgt gggacgccat tgaaggggtg ctgtgctgca gcagcgagga
     3181 ggtctcctca ggcattaccg ctctggtgtt cttggacaaa aggattgtgg ctgcacggct
     3241 caacggttcc cttgatttct tctccttgga gacccacact gccctcagcc ccctgcagtt
     3301 tagagggacc ccagggcggg gcagttcccc tgcctctcca gtgtacagca gcagcgacac
     3361 agtggcctgt cacctgaccc acacagtgcc ctgtgcacac caaaaaccca tcacagccct
     3421 gaaagccgct gctgggcgct tggtgactgg gagccaagac cacacactga gagtgttccg
     3481 tctggaggac tcgtgctgcc tcttcaccct tcagggccac tcaggggcca tcacgaccgt
     3541 gtacattgac cagaccatgg tgctggccag tggaggacaa gatggggcca tctgcctgtg
     3601 ggatgtactg actggcagcc gggtcagcca tgtgtttgct caccgtgggg atgtcacctc
     3661 ccttacctgt accacctcct gtgtcatcag cagtggcctg gatgacctca tcagcatctg
     3721 ggaccgcagc acaggcatca agttctactc cattcagcag gacctgggct gtggtgcaag
     3781 cttgggtgtc atctcagaca acctgctggt gactggcggc cagggctgtg tctccttttg
     3841 ggacctaaac tacggggacc tgttacagac agtctacctg gggaagaaca gtgaggccca
     3901 gcctgcccgc cagatcctgg tgctggacaa cgctgccatt gtctgcaact ttggcagtga
     3961 gctcagcctg gtgtatgtgc cctctgtgct ggagaagctg gactgagcgc agggcctcct
     4021 tgcccaggca ggaggctggg gtgctgtgtg ggggccaatg cactgaacct ggacttgggg
     4081 gaaagagccg agtatcttcc agccgctgcc tcctgactgt aataatatta aactttttta
     4141 aaaaaccata tcatcatctg tcaggcactt tgggagcta
//
