LOCUS       XM_047447733            4395 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens SREBF chaperone (SCAP), transcript variant
            X3, mRNA.
ACCESSION   XM_047447733
VERSION     XM_047447733.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4395
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4395
                     /gene="SCAP"
                     /note="SREBF chaperone; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 150 ESTs, 486 long SRA
                     reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 5 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
     CDS             383..4222
                     /gene="SCAP"
                     /codon_start=1
                     /product="sterol regulatory element-binding protein
                     cleavage-activating protein isoform X1"
                     /protein_id="XP_047303689.1"
                     /db_xref="GeneID:22937"
                     /db_xref="HGNC:HGNC:30634"
                     /db_xref="MIM:601510"
                     /translation="MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPL
                     LKLPLPGTGPVEFTTPVKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSV
                     FPWHKNLLAVDVFRSPLSRAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKL
                     RNLLPEHGCLLLSPGNFWQNDWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPG
                     KYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHF
                     KEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLC
                     TLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSI
                     MKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELA
                     DLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVY
                     FLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSG
                     MLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEEL
                     WRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPP
                     GPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
                     LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHV
                     CVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRH
                     RPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSC
                     LVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWS
                     LELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLD
                     FFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAA
                     AGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWD
                     VLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGA
                     SLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
                     GSELSLVYVPSVLEKLD"
ORIGIN      
        1 cccaggaaca actataggac caagagcaga gagttctacc agagtgaatt ttgcttggtg
       61 accattatgt cagagaccta agctttttag cgtttttatg ttgagggctg acctcgctag
      121 accttcttca cgagtgaatc actatttgta caacagtgtg ttttgaggag gccatcccta
      181 tgtaaagggt ttctctgtat ccctatgtaa aggacttttc tcagtgggat ttgtgcatag
      241 aggagggggg ggaagaatgc ctgtttgaca gagagcagct gaaggtacct gcacatgttg
      301 ttctttgtca gtgctgtcaa gtgtgtgcca gggtgatcca tggtcacttt ccgggatggc
      361 agcaaggtga cttcggctga ggatgaccct gactgaaagg ctgcgtgaga agatatctcg
      421 ggccttctac aaccatgggc tcctctgtgc atcctatccc atccccatca tcctcttcac
      481 agggttctgc atcttagcct gctgctaccc actgctgaaa ctccccttgc caggaacagg
      541 acctgtggaa ttcaccaccc ctgtgaagga ttactcgccc ccacctgtgg actctgaccg
      601 caaacaagga gagcctactg agcagcctga gtggtatgtg ggtgccccgg tggcttatgt
      661 ccagcagata tttgtgaagt cctcagtgtt tccctggcac aagaacctcc tggcagtaga
      721 tgtatttcgt tcacctttgt cccgggcatt ccaactggtg gaggagatcc ggaaccacgt
      781 gctgagagac agctctggga tcaggagctt ggaggagttg tgtctgcaag tgaccgacct
      841 gctgccaggc cttaggaagc tcaggaacct actccctgag catggatgcc tgctgctgtc
      901 ccctgggaac ttctggcaga atgactggga acgcttccat gctgatcctg acatcattgg
      961 gaccatccac cagcacgagc ctaaaaccct gcagacttca gccacactca aagacttgtt
     1021 atttggtgtt cctgggaagt acagcggggt gagcctctac accaggaaga ggatggtctc
     1081 ctacaccatc accctggtct tccagcacta ccatgccaag ttcctgggca gcctgcgtgc
     1141 ccgcctgatg cttctgcacc ccagccccaa ctgcagcctt cgggcggaga gcctggtcca
     1201 cgtgcacttc aaggaggaga ttggtgtcgc tgagctcatc ccccttgtga ccacctacat
     1261 catcttgttt gcctacatct acttctccac gcggaagatc gacatggtca agtccaagtg
     1321 ggggctggcc ctggctgccg tggtcacagt gctcagctcg ctgctcatgt ctgtgggact
     1381 ctgcacactc ttcggcctga cgcccaccct caatggcggc gagattttcc cctaccttgt
     1441 ggtggttatt gggttagaga atgtgttggt gctcaccaag tctgtggtct caaccccggt
     1501 agacctggag gtgaagctgc ggatcgccca aggcctaagc agcgagagct ggtccatcat
     1561 gaagaacatg gccacggagc tgggcatcat cctcatcggc tacttcaccc tagtgcccgc
     1621 catccaggag ttctgtctct ttgctgtcgt ggggctggtg tctgacttct tccttcagat
     1681 gctgtttttc accactgtcc tgtccattga cattcgccgg atggagctag cagacctgaa
     1741 caagcgactg ccccctgagg cctgcctgcc ctcagccaag ccagtgggac agccaacgcg
     1801 ctacgagcgg cagctggctg tgaggccgtc cacaccccac accatcacgt tgcagccgtc
     1861 ttccttccga aacctgcggc tccccaagag gctgcgtgtt gtctacttcc tggcccgcac
     1921 ccgcctggca cagcgcctca tcatggctgg caccgttgtc tggattggca tcctggtata
     1981 cacagaccca gcagggctgc gcaactacct cgctgcccag gtgacggaac agagcccatt
     2041 gggtgaggga gccctggctc ccatgcccgt gcctagtggc atgctgcccc ccagccaccc
     2101 ggaccctgcc ttctccatct tcccacctga tgcccctaag ctacctgaga accagacgtc
     2161 gccaggcgag tcacctgagc gtggaggtcc agcagaggtt gtccatgaca gcccagtccc
     2221 agaggtaacc tgggggcctg aggatgagga actttggagg aaattgtcct tccgccactg
     2281 gccgacgctc ttcagctatt acaacatcac actggccaag aggtacatca gcctgctgcc
     2341 cgtcatccca gtcacgctcc gcctgaaccc gagggaggct ctggagggcc ggcaccctca
     2401 ggacggccgc agtgcctggc ccccaccggg gcccatacct gctgggcact gggaagcagg
     2461 acccaagggc ccaggtgggg tgcaggccca tggagacgtc acgctgtaca aggtggcggc
     2521 gctgggcctg gccaccggca tcgtcttggt gctgctgctg ctctgcctct accgcgtgct
     2581 atgcccgcgc aactacgggc agctgggtgg tgggcccggg cggcggaggc gcggggagct
     2641 gccctgcgac gactacggct atgcgccacc cgagacggag atcgtgccgc ttgtgctgcg
     2701 cggccacctc atggacatcg agtgcctggc cagcgacggc atgctgctgg tgagctgctg
     2761 cctggcaggc cacgtctgcg tgtgggacgc gcagaccggg gattgcctaa cgcgcattcc
     2821 gcgcccaggc aggcagcgcc gggacagtgg cgtgggcagc gggcttgagg ctcaggagag
     2881 ctgggaacga ctttcagatg gtgggaaggc tggtccagag gagcctgggg acagccctcc
     2941 cctgagacac cgcccccggg gccctccgcc gccttccctc ttcggggacc agcctgacct
     3001 cacctgctta attgacacca acttttcagc gcagcctcgg tcctcacagc ccactcagcc
     3061 cgagccccgg caccgggcgg tctgtggccg ctctcgggac tccccaggct atgacttcag
     3121 ctgcctggtg cagcgggtgt accaggagga ggggctggcg gccgtctgca caccagccct
     3181 gcgcccaccc tcgcctgggc cggtgctgtc ccaggcccct gaggacgagg gtggctcccc
     3241 cgagaaaggc tccccttccc tcgcctgggc ccccagtgcc gagggttcca tctggagctt
     3301 ggagctgcag ggcaacctca tcgtggtggg gcggagcagc ggccggctgg aggtgtggga
     3361 cgccattgaa ggggtgctgt gctgcagcag cgaggaggtc tcctcaggca ttaccgctct
     3421 ggtgttcttg gacaaaagga ttgtggctgc acggctcaac ggttcccttg atttcttctc
     3481 cttggagacc cacactgccc tcagccccct gcagtttaga gggaccccag ggcggggcag
     3541 ttcccctgcc tctccagtgt acagcagcag cgacacagtg gcctgtcacc tgacccacac
     3601 agtgccctgt gcacaccaaa aacccatcac agccctgaaa gccgctgctg ggcgcttggt
     3661 gactgggagc caagaccaca cactgagagt gttccgtctg gaggactcgt gctgcctctt
     3721 cacccttcag ggccactcag gggccatcac gaccgtgtac attgaccaga ccatggtgct
     3781 ggccagtgga ggacaagatg gggccatctg cctgtgggat gtactgactg gcagccgggt
     3841 cagccatgtg tttgctcacc gtggggatgt cacctccctt acctgtacca cctcctgtgt
     3901 catcagcagt ggcctggatg acctcatcag catctgggac cgcagcacag gcatcaagtt
     3961 ctactccatt cagcaggacc tgggctgtgg tgcaagcttg ggtgtcatct cagacaacct
     4021 gctggtgact ggcggccagg gctgtgtctc cttttgggac ctaaactacg gggacctgtt
     4081 acagacagtc tacctgggga agaacagtga ggcccagcct gcccgccaga tcctggtgct
     4141 ggacaacgct gccattgtct gcaactttgg cagtgagctc agcctggtgt atgtgccctc
     4201 tgtgctggag aagctggact gagcgcaggg cctccttgcc caggcaggag gctggggtgc
     4261 tgtgtggggg ccaatgcact gaacctggac ttgggggaaa gagccgagta tcttccagcc
     4321 gctgcctcct gactgtaata atattaaact tttttaaaaa accatatcat catctgtcag
     4381 gcactttggg agcta
//
