LOCUS       NM_001199824            1270 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens SH3 domain binding kinase family member 3 (SBK3),
            mRNA.
ACCESSION   NM_001199824 XM_003120967
VERSION     NM_001199824.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1270)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
REFERENCE   3  (bases 1 to 1270)
  AUTHORS   Manning,G., Whyte,D.B., Martinez,R., Hunter,T. and Sudarsanam,S.
  TITLE     The protein kinase complement of the human genome
  JOURNAL   Science 298 (5600), 1912-1934 (2002)
   PUBMED   12471243
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008735.9, KF459708.1 and DB047407.1.
            
            On Mar 12, 2011 this sequence version replaced NM_001199824.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2151741,
                              SAMEA2155550 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000612221.1/ ENSP00000483467.1
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AC008735.9         130804-130848
            46-196              AC008735.9         131398-131548
            197-399             AC008735.9         132045-132247
            400-902             AC008735.9         134821-135323
            903-948             KF459708.1         1-46
            949-998             DB047407.1         249-298
            999-1028            KF459708.1         97-126
            1029-1270           AC008735.9         135449-135690
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..1270
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /note="SH3 domain binding kinase family member 3"
                     /db_xref="GeneID:100130827"
                     /db_xref="HGNC:HGNC:44121"
     CDS             1..1080
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /EC_number="2.7.11.1"
                     /note="Sugen kinase 110; SH3-binding domain kinase family
                     member 3"
                     /codon_start=1
                     /product="uncharacterized serine/threonine-protein kinase
                     SBK3"
                     /protein_id="NP_001186753.1"
                     /db_xref="CCDS:CCDS74457.1"
                     /db_xref="GeneID:100130827"
                     /db_xref="HGNC:HGNC:44121"
                     /translation="MERRASETPEDGDPEEDTATALQRLVELTTSRVTPVRSLRDQYH
                     LIRKLGSGSYGRVLLAQPHQGGPAVALKLLRRDLVLRSTFLREFCVGRCVSAHPGLLQ
                     TLAGPLQTPRYFAFAQEYAPCGDLSGMLQERGLPELLVKRVVAQLAGALDFLHSRGLV
                     HADVKPDNVLVFDPVCSRVALGDLGLTRPEGSPTPAPPVPLPTAPPELCLLLPPDTLP
                     LRPAVDSWGLGVLLFCAATACFPWDVALAPNPEFEAFAGWVTTKPQPPQPPPPWDQFA
                     PPALALLQGLLDLDPETRSPPLAVLDFLGDDWGLQGNREGPGVLGSAVSYEDREEGGS
                     SLEEWTDEGDDSKSGGRTGTDGGAP"
     exon            1..45
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /inference="alignment:Splign:2.1.0"
     exon            46..196
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /inference="alignment:Splign:2.1.0"
     exon            197..399
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /inference="alignment:Splign:2.1.0"
     exon            400..1270
                     /gene="SBK3"
                     /gene_synonym="SGK110"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagcgca gggcctccga gacccctgag gatggggacc cagaggagga cacagccaca
       61 gccctccaac ggctggtgga gctgacgacc agcagggtga ccccggtgag gagccttcgg
      121 gaccagtacc acctcatccg gaagctgggc tccggctcct acggccgcgt gctccttgcc
      181 cagcctcacc aggggggtcc agctgtggct ctgaagctcc tgcgtcggga tttggtcctg
      241 agaagcacct tcctgaggga gttctgtgtg ggccgctgcg tctctgcaca cccaggcctg
      301 ctgcagaccc tggcaggacc cctacagacc ccccgctatt ttgccttcgc ccaggagtac
      361 gcgccctgtg gggacctcag cgggatgctg caggaaaggg gcctcccaga actgctggtg
      421 aagcgggtgg tggcccagtt ggcaggagct ctggacttcc tccacagccg ggggctggtc
      481 cacgcagatg tcaaacctga caacgtgctg gtcttcgacc cggtctgcag ccgtgtggcc
      541 ctgggagacc tgggtctgac ccggccagag ggcagcccga cccccgcccc accagtgcct
      601 ctgcccacgg caccgcctga gctctgtctc ctgctaccgc ccgacaccct gcctctgcgg
      661 ccagccgtgg actcctgggg cctgggggtg cttctcttct gtgctgccac tgcctgtttc
      721 ccttgggacg tggcactggc ccccaaccct gagttcgagg ccttcgctgg ctgggtgacc
      781 accaagcctc agccacctca gccaccacca ccctgggacc agtttgcgcc cccagccctg
      841 gccttgctcc aggggcttct ggacctggat cccgagacta ggagcccccc actggctgtc
      901 ctggacttcc tgggggacga ctgggggttg caagggaaca gagagggacc tggggttttg
      961 gggagcgccg tgtcctatga ggacagggag gagggaggct caagcctgga ggagtggaca
     1021 gatgagggtg atgacagcaa aagtggtggg aggacgggga cagatggggg agctccctga
     1081 ccaggtgaca gagacaggtg gccagagcct gggccagagg cccttccccc agcccccagg
     1141 gccacctgga tggagagaca gctgcacccg ggaggacaga gagggaacac attgcactct
     1201 ccctacggaa cgctgggctt ggacgcgcat tcctcttcca actgaggacc caagagccca
     1261 gctcctgccc
//
