LOCUS       NM_198534               1690 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens stabilizer of axonemal microtubules 5 (SAXO5), mRNA.
ACCESSION   NM_198534 XM_351174
VERSION     NM_198534.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1690)
  AUTHORS   Leung,M.R., Zeng,J., Wang,X., Roelofs,M.C., Huang,W., Zenezini
            Chiozzi,R., Hevler,J.F., Heck,A.J.R., Dutcher,S.K., Brown,A.,
            Zhang,R. and Zeev-Ben-Mordehai,T.
  TITLE     Structural specializations of the sperm tail
  JOURNAL   Cell 186 (13), 2880-2896 (2023)
   PUBMED   37327785
REFERENCE   2  (bases 1 to 1690)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC008878.10, DB037908.1 and BC029824.1.
            
            On Nov 23, 2018 this sequence version replaced NM_198534.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC029824.1, BC034779.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000361664.7/ ENSP00000355241.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC008878.10        111472-111482
            12-51               DB037908.1         1-40
            52-1690             BC029824.1         1-1639
FEATURES             Location/Qualifiers
     source          1..1690
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.2"
     gene            1..1690
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /note="stabilizer of axonemal microtubules 5"
                     /db_xref="GeneID:374877"
                     /db_xref="HGNC:HGNC:24745"
     exon            1..135
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            136..729
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..1670
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /note="uncharacterized protein C19orf45; testis-expressed
                     protein 45; testis expressed 45"
                     /codon_start=1
                     /product="stabilizer of axonemal microtubules 5"
                     /protein_id="NP_940936.2"
                     /db_xref="CCDS:CCDS12179.2"
                     /db_xref="GeneID:374877"
                     /db_xref="HGNC:HGNC:24745"
                     /translation="MATGALLPCSRPCPMSRLDFLKASHFSLGPDLRLHEGTMRTTSH
                     RDFAYPAATREPPSLQPPPALLFPMDPRWDREERVSEAHRAFPPPSTPPWELLQAQAR
                     ERTLAMQAGNLHLHEDAHAGIGLSNAHAAYGWPELPARTRERIRGARLIFDRDSLPPG
                     DRDKLRIPPTTHQALFPPHDARPQPRAPSCHLGGPNTLKWDYTRQDGTSYQRQFQALP
                     GPPALRCKRASSGVELGDCKISYGSTCSEQKQAYRPQDLPEDRYDKAQATAHIHCVNI
                     RPGDGLFRDRTTKAEHFYAREPEPFVLHHDQTPESHILKGNWCPGPGSLDTFMQYFYG
                     QPPPPTQPPSRHVPHEKLQSHVTLGEPKLLKRFFKTTMGSDYCPSEWRQVQKAPNLHL
                     QQSYLPRGTGEFDFLTMNQKMLKPHRTPPAPVTEEMLQRCKYSHMEPPLGGLRFFSTQ
                     YKDEFPFKYQGPAALRLKNPQEGFVPLGTPHQRGCREKIDPLVPQPPMYLCPSQQ"
     exon            730..833
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            834..934
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1047
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1157
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1359
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1445
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1690
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1666..1671
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /note="hexamer: AATAAA"
     polyA_site      1690
                     /gene="SAXO5"
                     /gene_synonym="C19orf45; TEX45"
                     /note="major polyA site"
ORIGIN      
        1 ggaccaccct tggatgcagc ctgggaagga acatgaggat cctctgagag accagggaca
       61 gagggagacc caaagatctg gtctgtagct aagtgaattt tctaaaactc attgattcac
      121 acgccatccc ttgaggtggc tggtgtcccg cgatggccac aggcgccctc ctgccgtgct
      181 cgcgcccgtg cccgatgtcc cggctggact tcctcaaggc ctcgcacttc tcgctggggc
      241 ctgacctgcg gctgcacgag ggcaccatgc gcaccacgtc gcaccgggac tttgcctacc
      301 cggctgccac ccgggagccg ccgagcctgc agccgccgcc cgcgctgctt ttcccaatgg
      361 acccgcgctg ggaccgggaa gagcgcgtgt cggaggcgca ccgcgcgttc ccgccgccat
      421 ccacgccgcc gtgggagctg ctgcaagcgc aggcgcggga acgcacgctc gccatgcagg
      481 ccggcaacct gcacctgcac gaggacgcgc acgccgggat cggcctctcc aacgcgcacg
      541 ccgcctacgg ctggcccgag ctgccggcgc gcacccgaga gcggatccgc ggcgcgcgcc
      601 tcatcttcga ccgcgactcc ctgcctcctg gcgaccgcga caagttgcgc atcccgccca
      661 ccacgcacca ggcgctcttt ccaccccacg acgcgcgccc gcagcctcgc gcgcccagtt
      721 gccacctcgg gggccccaac accctcaagt gggactacac gagacaagat gggacttcct
      781 accaaagaca gttccaggcc ctgccaggcc cacctgcctt gaggtgtaag agggcctcct
      841 ccggagtgga gctgggagac tgcaagatca gctatggatc aacgtgttcg gagcagaaac
      901 aggcctacag gccccaggat ctgcctgaag ataggtatga caaggcccag gccacagccc
      961 acatccactg tgtaaatatc cgtcctggtg acggcctctt ccgcgacagg accaccaagg
     1021 ccgagcactt ctatgccagg gagccagagc cttttgttct tcaccacgat cagactccgg
     1081 agtcgcacat cctgaaagga aattggtgcc ccggccccgg cagtctggac accttcatgc
     1141 agtacttcta cggccagccg ccacccccga cccagccacc cagccgccac gtgcctcatg
     1201 agaaattgca gagtcatgtg accctagggg agccaaagct actcaaacgc ttcttcaaga
     1261 ccaccatggg ctcggactac tgcccttcag agtggagaca ggtgcagaaa gcgcccaacc
     1321 tccacttgca gcaaagctac ctgccgcggg gcacgggcga attcgatttt ttaaccatga
     1381 accagaagat gctgaagcca cacagaacac ctccggcccc ggtgactgaa gagatgctac
     1441 agcggtgcaa gtacagccac atggagcccc ctctgggtgg actgcgcttc ttctcaacac
     1501 aatacaagga cgagtttcct ttcaagtacc agggcccagc agccctgaga ctgaaaaatc
     1561 ctcaggaggg cttcgtgccc ctgggcacgc ctcaccagcg cggctgcagg gagaagatag
     1621 accctctggt cccccagccc cctatgtacc tgtgccccag ccagcaataa atgccatctt
     1681 ggcaacattc
//
