LOCUS       NM_001367857            2821 bp    mRNA    linear   PRI 17-OCT-2024
DEFINITION  Homo sapiens spermidine/spermine N1-acetyl transferase like 1
            (SATL1), transcript variant 1, mRNA.
ACCESSION   NM_001367857
VERSION     NM_001367857.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2821)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC003001.1, Z99571.2 and Z83820.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_001367857.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.70738.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA1968968,
                                           SAMEA2148874 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000644105.2/ ENSP00000494345.1
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-192               AC003001.1         69062-69253         c
            193-314             AC003001.1         49679-49800         c
            315-2267            Z99571.2           17035-18987         c
            2268-2319           Z99571.2           13571-13622         c
            2320-2400           Z99571.2           4623-4703           c
            2401-2502           Z99571.2           3835-3936           c
            2503-2543           Z99571.2           2892-2932           c
            2544-2811           Z99571.2           2001-2268           c
            2812-2821           Z83820.2           171627-171636       c
FEATURES             Location/Qualifiers
     source          1..2821
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq21.1"
     gene            1..2821
                     /gene="SATL1"
                     /note="spermidine/spermine N1-acetyl transferase like 1"
                     /db_xref="GeneID:340562"
                     /db_xref="HGNC:HGNC:27992"
                     /db_xref="MIM:301129"
     exon            1..192
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            193..314
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            315..2267
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             627..2714
                     /gene="SATL1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     spermidine/spermine N(1)-acetyltransferase-like protein 1"
                     /codon_start=1
                     /product="spermidine/spermine N(1)-acetyltransferase-like
                     protein 1 isoform 1"
                     /protein_id="NP_001354786.1"
                     /db_xref="CCDS:CCDS94638.1"
                     /db_xref="GeneID:340562"
                     /db_xref="HGNC:HGNC:27992"
                     /db_xref="MIM:301129"
                     /translation="MNQSGTNQSSLSDSNQAGINQPSTNSLGMNQMDMNQGSASLYEM
                     NQVDMKQPSMSQAGMRQSGTNLPDINQPDMKQPDTWQLGRSQPGMLQQELSQLVLSKA
                     GISQPDPSQPGPSQSGPSQSRMRQIGTNQSGMSQPVMQQLDSQSGGSQPSMRQVGTSQ
                     LGTSQIGMSQPGTWQTGLSQPVLRQPNMSPPGMWQPGVQQPGISQQVPSHPDMSQPGM
                     SQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQMDM
                     NQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQ
                     SLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGS
                     QPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQV
                     PSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQ
                     PGRSQPSVSQMGMRQTSMDYFQIRHAEAGDCPEILRLIKELAACENMLDAMELTAADL
                     LRDGFGDNPLFYCLIAEVNDQQKPSGKLTVGFAMYYFTYDSWTGKVLYLEDFYVTQAY
                     QGLGIGAEMLKRLSQIAITTQCNCMHFLVVIWNQASINYYTSRGALDLSSEEGWHLFR
                     FNREELLDMAWEE"
     exon            2268..2319
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2400
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2401..2502
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2503..2543
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     exon            2544..2821
                     /gene="SATL1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2800..2805
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SATL1"
                     /note="hexamer: AATACA"
     polyA_site      2821
                     /gene="SATL1"
                     /note="major polyA site"
ORIGIN      
        1 agatctcggc gcgcccctga ggagtttctg tgggaagatt ttctgttttc caggtttccc
       61 aagggaaacg aagaaaggga ggaggataat caatgactga acctctaata gatgttggac
      121 gacgttaaaa aaaaaatgta tcggccctac cctcgaggat ttgacaaatt agactgacca
      181 gagtaataag agatacaggc agaagaggag acatagacac acacagagga gaagatgatg
      241 tgaaaaggga ggcagagatc acagtggtgt ggctacaagc caagaaatac cgaagccatc
      301 agaagttgga agagggaaag gccagatgac aacctgaaac tcagccaagc ttgcagctgt
      361 ggtcgctggt gaagtcaact ccagcaaacc ggaggcatta ataatcttcc tgaggtgctc
      421 ctctcttttt ccaattccca ccttgataga ggggtatctc aaagtgggcg aatcaaattg
      481 agaagaactg ggaacagcca acaacctccc accacagcac agttaaggga ttctgttcca
      541 tcaagacagc catcagccaa tcagttgtct gccaacccat catctgccac cccatcctta
      601 gtcaacaaag caggaatcaa ctgggcatga accaatcagg cacgaaccaa tcaagtttat
      661 cagactcgaa ccaagcaggc ataaaccagc caagcacaaa ctcacttggt atgaaccaaa
      721 tggacatgaa ccaagggagt gcaagcctat atgaaatgaa ccaagtggac atgaaacaac
      781 caagcatgag ccaagctggc atgaggcaat caggtacaaa cctaccagac ataaaccaac
      841 ccgacatgaa acaaccagac acatggcaat taggtaggag ccaaccaggc atgctgcaac
      901 aagaactgag ccaactagtc ctgagcaaag caggcataag ccaaccagac ccatcgcaac
      961 caggcccaag ccaatcaggc cccagccaat cacgcatgag gcaaataggc acgaaccaat
     1021 caggtatgag ccaaccagtg atgcagcaac tagacagcca gtcaggtggg agccaaccaa
     1081 gcatgagaca agtaggcacc agccaattag gcacaagcca aataggcatg agccaaccag
     1141 gcacatggca aacaggactg agccaaccag tcctgaggca accaaacatg agtccaccag
     1201 gcatgtggca accaggcgtg caacaaccag gcatcagcca gcaagtccca agccacccag
     1261 acatgagtca accaggcatg agccagcaag tccccagcca accaggcata aggcaaccag
     1321 acactagcca atcatgtaag aaccaaacag acatgagcca accagacgca aaccaatcaa
     1381 gtttatcaga ttccaaccaa acaggtataa tccagccaag cccaagctta cttggtatga
     1441 accaaatgga catgaaccaa tggagtgcaa gcctatatga aatgaaccaa gtggacatga
     1501 aacaaccaag catgagccaa gctggcatga ggcaatcagg tacaaaccta ccagacataa
     1561 accaacctgg catgaaacaa ccaggcacat ggcaattagg taggagccaa ccaggcatgt
     1621 ggccacaaag cctgagcgaa ctagtcctga gtgaagcaag cataagccaa ccaggtccac
     1681 cgcaacgagc cccaagccaa tcaggcccca gacaatcaag cacgagccaa gcaggcacaa
     1741 accaatcagg tataagccaa ccagtgatgt ggcaactaga catgagacag tcaggtggga
     1801 gccaaccaag catgagacaa gtaggcacca gccaatcagg cacaagccaa ataggcatga
     1861 gccaaccagg cacatggcaa acaggcctga gccaaccagt cccgaggcaa ccaaacaaga
     1921 gtccaccagg catgtggcaa cgaggcatgt ggcaaccagg catgagccag caagtcccca
     1981 gccaactagg catgagacaa ccaggcacta gccaatcaag taagaaccaa acaggcatga
     2041 gccatccagg caggggccaa ccaggcatat gggaaccggg gccgagtcag ccaggcctga
     2101 gccaacaaga cctgaaccaa ttagtgctga gccaaccagg cctgagtcaa ccaggcagga
     2161 gccaaccaag tgtgagccaa atgggcatga ggcaaacaag catggattac tttcaaataa
     2221 gacatgcaga ggctggagac tgcccagaaa ttttgcgact gattaaagaa ttggctgcct
     2281 gtgaaaacat gctagatgca atggagttaa cagcagctga tttactcaga gatggctttg
     2341 gggacaatcc ccttttctac tgcctgattg cagaagtaaa cgatcaacaa aaaccatcag
     2401 gcaaactgac tgttggattt gccatgtact actttacata cgactcatgg actggcaagg
     2461 tactttacct agaggacttt tatgtcacac aagcttacca aggcctaggt attggagctg
     2521 aaatgctgaa gaggctaagt cagatagcca tcacaactca atgtaactgc atgcactttc
     2581 ttgtcgtcat ttggaaccag gcttctatca actactatac tagtcgaggg gctttagacc
     2641 tttcctctga ggagggctgg catctcttca ggtttaacag agaagaactc ctggacatgg
     2701 catgggaaga atgaaagagg ctttgtaaca actcatccca acacagcctc caacatttga
     2761 ctgtcacctg agtctaacag cagtttgact ttgttgtaca atacagcaag tgatcatcac
     2821 a
//
