LOCUS       NM_001039651            1255 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens suppressor APC domain containing 1 (SAPCD1), mRNA.
ACCESSION   NM_001039651
VERSION     NM_001039651.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1255)
  AUTHORS   Barcellos,L.F., May,S.L., Ramsay,P.P., Quach,H.L., Lane,J.A.,
            Nititham,J., Noble,J.A., Taylor,K.E., Quach,D.L., Chung,S.A.,
            Kelly,J.A., Moser,K.L., Behrens,T.W., Seldin,M.F., Thomson,G.,
            Harley,J.B., Gaffney,P.M. and Criswell,L.A.
  TITLE     High-density SNP screening of the major histocompatibility complex
            in systemic lupus erythematosus demonstrates strong evidence for
            independent susceptibility regions
  JOURNAL   PLoS Genet 5 (10), e1000696 (2009)
   PUBMED   19851445
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1255)
  AUTHORS   Xie,T., Rowen,L., Aguado,B., Ahearn,M.E., Madan,A., Qin,S.,
            Campbell,R.D. and Hood,L.
  TITLE     Analysis of the gene-dense major histocompatibility complex class
            III region and its comparison to mouse
  JOURNAL   Genome Res 13 (12), 2621-2636 (2003)
   PUBMED   14656967
REFERENCE   4  (bases 1 to 1255)
  AUTHORS   Albertella,M.R., Jones,H., Thomson,W., Olavesen,M.G. and
            Campbell,R.D.
  TITLE     Localization of eight additional genes in the human major
            histocompatibility complex, including the gene encoding the casein
            kinase II beta subunit (CSNK2B)
  JOURNAL   Genomics 36 (2), 240-251 (1996)
   PUBMED   8812450
REFERENCE   5  (bases 1 to 1255)
  AUTHORS   Sargent,C.A., Dunham,I. and Campbell,R.D.
  TITLE     Identification of multiple HTF-island associated genes in the human
            major histocompatibility complex class III region
  JOURNAL   EMBO J 8 (8), 2305-2312 (1989)
   PUBMED   2477242
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662899.5.
            
            On Jun 8, 2021 this sequence version replaced NM_001039651.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.3412729.1,
                                           SRR14038192.38575.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000415669.4/ ENSP00000411948.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-513               AL662899.5         104997-105509
            514-654             AL662899.5         105756-105896
            655-750             AL662899.5         106405-106500
            751-840             AL662899.5         106607-106696
            841-1255            AL662899.5         106777-107191
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.33"
     gene            1..1255
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /note="suppressor APC domain containing 1"
                     /db_xref="GeneID:401251"
                     /db_xref="HGNC:HGNC:13938"
     exon            1..513
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /inference="alignment:Splign:2.1.0"
     CDS             400..936
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /note="protein G7d"
                     /codon_start=1
                     /product="suppressor APC domain-containing protein 1"
                     /protein_id="NP_001034740.1"
                     /db_xref="CCDS:CCDS34411.1"
                     /db_xref="GeneID:401251"
                     /db_xref="HGNC:HGNC:13938"
                     /translation="MGSQGSGGVPLVQAPYTVLLLPLGTSRQDPGAQSFFLWLRRMQA
                     LEREQDALWQGLELLQHGQAWFEDHLREAQRQQLHLGALGENFLTDLHSEPGRPPLAQ
                     IQKVNICLQNLIHEKFSPSPLNKASSCTTQDSKERRREQNLWQQQELSRQQKGVTQPK
                     EEMAQRGCTKGPRGPTRV"
     exon            514..654
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /inference="alignment:Splign:2.1.0"
     exon            655..750
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /inference="alignment:Splign:2.1.0"
     exon            751..840
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1255
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1214..1219
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /note="hexamer: AATAAA"
     polyA_site      1255
                     /gene="SAPCD1"
                     /gene_synonym="C6orf26; NG23"
                     /note="major polyA site"
ORIGIN      
        1 ataaagttta ttttgaagaa agatattgtt tctttagtct caaaacaaga gactaggaaa
       61 gatccaaaac acagagcagg agtccacagg ggaacctgcc ctgcctcagt aaaaatacag
      121 tgttgttgct gtaggaagac tcccggattc taccccagga tacttcatga gaacgaaccc
      181 cttcagagag gccctacaaa acagattaga gggaagacag aggggtccaa gggagatggt
      241 ctctcttctc aagtaggaac accccagcct cagacagaca cagcaggaag gggcctgaga
      301 ggctgacaga ggcaggatgg gtgcaaggca ggggtggagg ggagggacca gcccgggctg
      361 caccagtggg agtggctcca cccttcccac ctcagagcca tggggagcca gggctctggc
      421 ggggtgccct tggtgcaggc tccctacaca gtcctgctgc tgccgctggg gacaagccgc
      481 caagacccag gggcccagag cttcttcctt tggctacgca ggatgcaggc tctggagaga
      541 gaacaggatg ccctgtggca gggtctggag ctgctacagc atggccaggc ctggtttgaa
      601 gaccatctga gggaggcaca gcgacagcag ctgcatctag gggcccttgg tgagaatttt
      661 ctaacagatt tacactcaga gcctggtcgc cccccgttag cccagattca aaaggtgaac
      721 atctgtttgc agaatctgat tcatgagaag ttctccccaa gtccactgaa caaggctagt
      781 tcctgcacca cccaggattc aaaggaaaga cgaagggagc agaacttgtg gcagcaacag
      841 gagttgtcaa ggcagcagaa aggagtcacc cagccaaagg aggagatggc tcagcggggc
      901 tgcaccaagg ggccaagagg ccctacccgt gtctaaaccc tcctctcact cccctaagcc
      961 tggtgaaaga gtcagaagcc ccaggctcct ttttctgttt cttaactcaa cagctaaaaa
     1021 atggctccag gtagtgagtc aatgaagttc agacatgttg gtgtaaagtt tctcctctgc
     1081 tcctgaaaac ttcatcttct tggtgtctca tgtcctcatt ctcccctata tgacatgcaa
     1141 aaacgatctt tctttgaaat ccctctggga agaagcatgt ttattgaaac tgtccttcag
     1201 ccttaaatac aaaaataaaa ctgaaactgc tccagaaagc agctttctcc aaaaa
//
