LOCUS       NM_001010860            2984 bp    mRNA    linear   PRI 13-FEB-2025
DEFINITION  Homo sapiens sterile alpha motif domain containing 15 (SAMD15),
            mRNA.
ACCESSION   NM_001010860 XM_370769
VERSION     NM_001010860.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2984)
  AUTHORS   Heilig,R., Eckenberg,R., Petit,J.L., Fonknechten,N., Da Silva,C.,
            Cattolico,L., Levy,M., Barbe,V., de Berardinis,V., Ureta-Vidal,A.,
            Pelletier,E., Vico,V., Anthouard,V., Rowen,L., Madan,A., Qin,S.,
            Sun,H., Du,H., Pepin,K., Artiguenave,F., Robert,C., Cruaud,C.,
            Bruls,T., Jaillon,O., Friedlander,L., Samson,G., Brottier,P.,
            Cure,S., Segurens,B., Aniere,F., Samain,S., Crespeau,H., Abbasi,N.,
            Aiach,N., Boscus,D., Dickhoff,R., Dors,M., Dubois,I., Friedman,C.,
            Gouyvenoux,M., James,R., Madan,A., Mairey-Estrada,B., Mangenot,S.,
            Martins,N., Menard,M., Oztas,S., Ratcliffe,A., Shaffer,T.,
            Trask,B., Vacherie,B., Bellemere,C., Belser,C., Besnard-Gonnet,M.,
            Bartol-Mavel,D., Boutard,M., Briez-Silla,S., Combette,S.,
            Dufosse-Laurent,V., Ferron,C., Lechaplais,C., Louesse,C.,
            Muselet,D., Magdelenat,G., Pateau,E., Petit,E.,
            Sirvain-Trukniewicz,P., Trybou,A., Vega-Czarny,N., Bataille,E.,
            Bluet,E., Bordelais,I., Dubois,M., Dumont,C., Guerin,T.,
            Haffray,S., Hammadi,R., Muanga,J., Pellouin,V., Robert,D.,
            Wunderle,E., Gauguet,G., Roy,A., Sainte-Marthe,L., Verdier,J.,
            Verdier-Discala,C., Hillier,L., Fulton,L., McPherson,J.,
            Matsuda,F., Wilson,R., Scarpelli,C., Gyapay,G., Wincker,P.,
            Saurin,W., Quetier,F., Waterston,R., Hood,L. and Weissenbach,J.
  TITLE     The DNA sequence and analysis of human chromosome 14
  JOURNAL   Nature 421 (6923), 601-607 (2003)
   PUBMED   12508121
  REMARK    Erratum:[Nature. 2023 Aug;620(7973):E17. doi:
            10.1038/s41586-023-06403-y.. PMID: 37491470]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007954.7.
            
            On Apr 12, 2021 this sequence version replaced NM_001010860.3.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK292571.1, SRR18074968.3520793.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000216471.5/ ENSP00000216471.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1729              AC007954.7         164358-166086
            1730-1828           AC007954.7         167362-167460
            1829-2984           AC007954.7         177987-179142
FEATURES             Location/Qualifiers
     source          1..2984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..2984
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="sterile alpha motif domain containing 15"
                     /db_xref="GeneID:161394"
                     /db_xref="HGNC:HGNC:18631"
     exon            1..1729
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..2065
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="family with sequence similarity 15, member A; SAM
                     domain-containing protein C14orf174; SAM domain-containing
                     protein 15"
                     /codon_start=1
                     /product="sterile alpha motif domain-containing protein
                     15"
                     /protein_id="NP_001010860.1"
                     /db_xref="CCDS:CCDS32126.1"
                     /db_xref="GeneID:161394"
                     /db_xref="HGNC:HGNC:18631"
                     /translation="MAEVPEDYDSGPDEDGELEPERPELPGLHKLYENAEPDTMAKAD
                     SKLPAEIYQEPQPETEEEDFKEGEPDSAKNVQLKPGGTSQEGIAKESKRDVPSETEPG
                     IHQEVKSETSREMGEFFKDLEAPMDETHKESDLEPPEEAKPNVTEDVFLESAMETDPD
                     PVPPTETMSEVSGATVRERNLELLEEETEPGVPEESLRVQHEETGLEPPEQTKQDFPS
                     EKLGESLEETDLQPPKMTKPETPEETQRESTEKKRTEPPEQARLEFLEKEPRKSSEEA
                     GLEPPEETQPEVPEEMQRKATEEKGTELPERTKPDFPDHKPRKSTDENVPEPLEEIKL
                     EFPEEESRKTNEETILEQSEMMKPESPEEIRKSNEKKNPQPPEETGPVLPQEINPQVE
                     EKTQTKPTEKILELPDETKPRETHVEFSKEDRPEPIKSKYSVGNDELEHREPKRGKLS
                     LSDKFRKEYYALGSLRESEESIGTHYEFLQPLQKLLNVSEECSYSDPSESQTELSEFV
                     HEKEVVDLSQELKERVSEDDETQPEKGTELQFEHLNWDPEEVAEWISQLGFPQYKECF
                     ITNFISGRKLIHVNCSNLPQMGITNFEDMKAISRHTQELLEIEEPLFKRSISLPYRDI
                     IGLYLEQKGHTGIKSDSLTLSEFVKAAGLQDYAPEITAPEENEELPCTEP"
     exon            1730..1828
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..2984
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="hexamer: ACTAAA"
     polyA_site      2117
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="major polyA site"
     regulatory      2967..2972
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="hexamer: AATAAA"
     polyA_site      2984
                     /gene="SAMD15"
                     /gene_synonym="C14orf174; FAM15A"
                     /note="major polyA site"
ORIGIN      
        1 ggggttgcta ggaagccgcg gcgcgtctgc taagctgcaa atggctgaag tcccggagga
       61 ttatgattcc ggcccagatg aagatggaga gctggagcct gagaggcctg aactgcctgg
      121 acttcataaa ttgtatgaaa atgccgaacc agacaccatg gcaaaggcag actcgaagct
      181 accagcagag atttaccaag agccacagcc agagaccgag gaagaggact tcaaagaggg
      241 ggagccagac agtgctaaga acgtgcagct gaaacctggc gggacgtccc aggaaggaat
      301 tgccaaggag tccaagagag acgtaccaag cgaaactgaa ccagggatac accaagaggt
      361 aaagtcggaa acatccagag agatgggaga gtttttcaaa gatttggagg cccctatgga
      421 tgaaacgcat aaagagtcag acctagagcc accagaggag gctaaaccaa atgttacaga
      481 ggatgtgttc ctagagtcag ctatggaaac agatccagat ccagtgccac caacggaaac
      541 catgtctgag gtttcggggg ccacagtcag agagagaaat ttagaattac tagaggagga
      601 gactgaaccg ggggttccag aggaatcact tagagtgcaa catgaagaga caggtctaga
      661 gcctccagag cagaccaaac aagattttcc aagtgagaaa ctaggagaat cacttgaaga
      721 gacagatctt cagccaccaa agatgaccaa accagagact ccagaggaga cacaaagaga
      781 gtcaactgag aagaaaagga cagagccacc cgagcaggct agactggaat ttctggagaa
      841 ggaaccaaga aagtctagtg aggaggcagg tctagagcct ccagaagaga ctcaaccaga
      901 ggttccagag gagatgcaaa gaaaggcaac tgaggagaaa gggacagaac tacctgagcg
      961 gactaaacca gactttccag accacaagcc aagaaagtct actgatgaga acgttcctga
     1021 gccactagaa gagatcaaat tagagtttcc tgaggaagaa tcaagaaaaa caaatgagga
     1081 aacaattcta gaacaatcag aaatgatgaa accagaaagt ccagaagaga taagaaagtc
     1141 aaatgagaaa aaaaatccac agccaccaga ggagactggt ccagtgctac cacaggagat
     1201 caacccacaa gttgaagaga aaacacaaac aaagccaact gagaaaattc tagagttacc
     1261 agatgaaacc aaaccaaggg agacacatgt agaattttcc aaggaagaca ggccagaacc
     1321 aataaagtct aagtattctg taggaaacga tgagctagag caccgtgagc ctaaaagagg
     1381 aaagttgtca ctaagtgaca aatttagaaa agaatattac gcattaggat ctctcagaga
     1441 aagtgaagaa tcaattggta cacattatga gtttttgcaa ccactccaaa aattgcttaa
     1501 tgtcagtgaa gaatgctcat actcagatcc ctcagagtct cagacagaat taagtgagtt
     1561 cgttcatgaa aaggaagttg tagatttgtc ccaagagttg aaggaacggg tctctgaaga
     1621 tgacgaaacc cagccagaaa aagggactga gttacaattt gagcatctta attgggatcc
     1681 agaggaagtt gcagagtgga ttagccagct aggcttccct caatacaagg agtgttttat
     1741 cacaaacttc atcagtggcc gaaaactcat tcacgtcaac tgctcaaacc tccctcagat
     1801 ggggataaca aactttgagg acatgaaggc aatttctcgg catacgcagg agctcctgga
     1861 aattgaagag ccattattca aacgctccat cagccttccc tatagggata ttatcggctt
     1921 atatttagag caaaaaggtc atactgggat aaaatctgat tccttgactt tatctgaatt
     1981 tgtcaaagca gcaggattac aggattatgc tccagaaata actgcccctg aagagaatga
     2041 ggaattacct tgcactgaac cataggggaa atccacttca cagagcttga aagatcaaac
     2101 taaattactt gagggaagag gtatggtctt ttttggtttt ctttttctcc tttttttttt
     2161 ttttattttt ttgagacaga gtcttgctct gtcgcccagg ctggagtgca atggcacagt
     2221 ctcagctcac tgcaaccttg cgattctcct gtctcagcct cccgagtagc tgggattaca
     2281 ggcatccgcc atcatgccca gctaattttt gtatttttag tagatatgat gtttcaccat
     2341 gttggccagg ctggtctgaa actcctaaca gttgatctgc ccgccgtggc gtcccaaagt
     2401 gctgggatta caagcgtgac ctaccgcacc tggccctttt tctccttttc attaaggatc
     2461 agttagaact gctggcttca ttcctagttg tgtctctgac ttatggtacc ctccctttct
     2521 ttttgcaatt taaccccttg ttaaaacaaa gatagtcacg cttatctttc tgggtaatta
     2581 taagaattcc tgagccgggc aaggtggctc acacctgtaa tcctagctct ttgggtggct
     2641 gaggcgggca gatcacctaa ggtcaggatt tcaagaccag cctggccaac aaggtgaagc
     2701 cctgtctcta ctaaaaatac aaaaattagc tgggcatggt ggcacatgcc tgtagtccca
     2761 gctactcagg aggctgaggc agaagaatca tttgaaccca ggaaacagag gttatagtga
     2821 gctgagatgg tgccactgga ctccagcctg ggtgacagag tgagactctg tctaaaacaa
     2881 acaaacaaaa caaagcaaaa caaaattcct gaaaaattct agtaatgcac cttgtaatag
     2941 gaacatgttg gggaaatata attaaaaata aaatctcctg ccaa
//
