LOCUS       XM_017025694            7427 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens rotatin (RTTN), transcript variant X7,
            mRNA.
ACCESSION   XM_017025694
VERSION     XM_017025694.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000018.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017025694.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7427
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
     gene            1..7427
                     /gene="RTTN"
                     /gene_synonym="MSSP"
                     /note="rotatin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 5 mRNAs, 49 ESTs, 481
                     long SRA reads, 6 Proteins, and 90% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     15 samples with support for all annotated introns"
                     /db_xref="GeneID:25914"
                     /db_xref="HGNC:HGNC:18654"
                     /db_xref="MIM:610436"
     CDS             266..6307
                     /gene="RTTN"
                     /gene_synonym="MSSP"
                     /codon_start=1
                     /product="rotatin isoform X7"
                     /protein_id="XP_016881183.1"
                     /db_xref="GeneID:25914"
                     /db_xref="HGNC:HGNC:18654"
                     /db_xref="MIM:610436"
                     /translation="MQDFPAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQ
                     LCMYLRNRLNFHRDPGFFSNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVV
                     GRTGQRPRGDGQDWDAASSSGSSSHAHVNSRISVHSPLDMGHIDLPELETEDTLELQF
                     QQLSLPQFCVSILESAVPLLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFG
                     IDMKEKLLLVLGALGETMCYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPV
                     EKASEFLSEPMSTALFLLSLDMPISLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAVY
                     SIECTCNFLSDIGKEGEKNLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQ
                     ASPLLQGESQKVLLHMLSHPLPRVKAETYHCCLEITKECLGVHNVTKPVSSLCNGIHF
                     LLHPKVLYEISVFGIQEPESEQVNTAAKAILLYLLQGRLMMTALTWNKFIESLCPVIP
                     ILQGYADTEDPLGNCILLLSKASSDTEEMLPCTTRLKSMLRLLLVKKPSVRSLALKLL
                     AFHLTSEEGADTKRPLIDARVLSRVTDLFIGKKPIELRLDDRRELVIKLETVEKVYEI
                     FTSDDVDLVLRKSAAEQLAVIMQDIKMHAVVKKLCLIDKIIEYLNECVSQDGKVVECL
                     VQPCLTLLRKVLCGDPVMRVSLSQQSSLLTVLFRVSLIFHEDCSVVTEVGALFCLLLF
                     DEVSRMDMWSVNPSNKPSLPSVFSLPVSVFRRYHLPVHVIGHHAVSPYSIVLPLSADC
                     LALKPVSDMLRIAWNLSWYHGSDNLLKQMNSETKTQEILDALKLSTEDILTLKITHMA
                     SGLQDCLHSIVQAATHREVRAAVTRMSFYLLNDRLSLKGCPGPCGVTLKSLAWHTALN
                     RFLQVLPACTEDEKLLIDIIHFLNKLIKEQRKNSSLELLNWILELLLRHSANPLLDLL
                     VLTESQAREETDDIRTAVRQQLQKELIALFDTLLLNFMEVTDRKCSELLYVFQTQLAL
                     KLLQCLKVTDAPHFYGLPSLERTLRGMANLTAFPGWSSHSPLTKPLDICVKYLSGLLE
                     VITSFYVERGGNAMSFMGKGVTKSTILCLLHLSHEMMAQAGSLEWMSLWFLPLGSHSE
                     EHIPTQQGLAWLIPLWVDRDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGT
                     VVNILLDQSECSMVRREAAFILQNLLVIPMPTEIIKDYTWQGPCVHDEDSGLSLIGKP
                     ALQALLYHCHFYEHLNQMVKHCYLGRCMFDLNFSAFDRNSESNDLNGLDDSFKFWRAP
                     SRTSQDRDPSSLSTSETTVAPSLGSTEFQPLVQSTTLLPEASHDQFVAQGHQESTSPR
                     PPHDSSLSAPLPKLCVFVTPSLLSAMCSLLDNLLTIAPRDTAKAFRQAHLIELLCSIA
                     DATLIQTCVQELRALLPSSPPAEHTQAQVSFLLEYLSSLSRLLQSCLLVEPDLVIQDE
                     LVKPLITNIIGILTICTKDVLDKELISAFYHTWTHLFNLLAMLLRKAGAITLPFVTVA
                     LAKHWTAAIDMFCTCAGLSATCPALYTASLQFLSVLLTEEAKGHLQAKSKTHLCCSPT
                     VASLLDDSQENQKSLEQLSDVILQCYEGKSSKDILKRVAANALMSLLAVSRRAQKHAL
                     KANLIDNCMEQMKHINAQLNLDSLRPGKAALKKKEDGVIKELSIAMQLLRNCLYQNEE
                     CKEAALEAHLVPVLHSLWPWILMDDSLMQISLQLLCVYTANFPNGCSSLCWSSCGQHP
                     VQATHRGAVSNSLMLCILKLASQMPLENTTVQQMVFMLLSNLALSHDCKGVIQKSNFL
                     QNFLSLALPKGGNKHLSNLTILWLKLLLNISSGEDGQQMILRLDGCLDLLTEMSKYKH
                     KSSPLLPLLIFHNVCFSPANKPKILANEKVITVLAACLESENQNAQRIGAAALWALIY
                     NYQKAKTALKSPSVKRRVDEAYSLAKKTFPNSEANPLNAYYLKCLENLVQLLNSS"
     polyA_site      7427
                     /gene="RTTN"
                     /gene_synonym="MSSP"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 aattgtcaaa aaaccctgaa atcttaacag gatattttcc ccaagacaaa agtaatttcc
       61 agcagatgga agtgccgcca cgaccagtgg atttgctctt tcactgacag taaatcagac
      121 tgtgaagtgc ttgaagtttt ctacatttcc ttggctaccc ctgaccacca cagacagaca
      181 tgtcctctcc tctaatgaaa gctctttaag aagtagtaac cacactttaa tctggaacac
      241 ctgtgaacta ttgaaggatg ttatcatgca agattttcct gctgagattt tccttcaaag
      301 gccaaaaatt gttcagagcc ttttatctct gttgaaactg gcctttggag atggaaagca
      361 tcgcctggca ttacagtcgg tgtcctgcct gcagcagctg tgcatgtatt taagaaacag
      421 acttaacttt caccgagatc caggtttttt ctccaataaa cacgacacag tttcccaaaa
      481 ttcttctttg tcttattgtc atgaagcaag aggtactcat cattcccaga atccttcccc
      541 aggaagcagc agccctcggc cttctgtggt tgggcgcaca ggccagcgac ccagaggaga
      601 tggccaggac tgggatgcag cgtcctctag tggaagtagt agtcatgctc atgtaaactc
      661 caggatatcc gttcattcac ctttggatat gggacacata gatctgccag agctggaaac
      721 tgaagacaca ttggaactac aattccagca gctcagtctt ccccagtttt gtgtctccat
      781 tctggaatca gctgttcctc tcttaagaac aggtagcaga caagtgataa taagagttct
      841 ggaattgctt acagaggata tgacacttat tggtgaagca atttcaacag atatctggga
      901 tgacagcagc ctttttggta tagatatgaa ggagaaacta ctcctggtgt tgggagccct
      961 tggagaaacc atgtgctacc ataaaagtag tatcagtttg gagcagccag aggtgatgct
     1021 tgtgcaccac agaatggcct ttatcagcat ttccctgttt gcagttcgac tgctacaaac
     1081 gcttctccct gttgaaaagg caagcgagtt tttatcagag cctatgtcaa cagcattatt
     1141 tctcctttct ttggacatgc ctatttcttt ggaatatcca aatattcatg aagctgttgt
     1201 ggcctatttg gaacagctga attctgaaaa ctacagtatt tataaacgaa ctgcagaggc
     1261 cgtttattca attgaatgca cctgtaactt cctgtctgat attgggaaag agggagagaa
     1321 gaatctctta gaattagtgg agctggcaga ccaagccttg cgtagctttt cctatcatca
     1381 gcatttcccg ctaataaagg aaatcatcag catttgttca aagatctgga aatctgctca
     1441 ggccagtcca ttactacaag gagaaagtca gaaggtgctt ctccatatgt tgtctcaccc
     1501 attgccacga gtgaaagctg aaacttacca ctgctgtctg gaaatcacga aggaatgttt
     1561 aggtgtccat aatgtcacta aacccgtgtc ttcactttgc aatggaattc attttctact
     1621 tcatccaaaa gttctgtatg aaatctctgt atttggcatt caagagcccg aaagtgagca
     1681 ggtgaacact gctgccaagg ccattctgtt atacctgctt cagggacgat tgatgatgac
     1741 agcattgacc tggaacaagt ttattgaatc tctctgtcct gtcatcccaa tactacaggg
     1801 ctatgccgac acagaagatc ctctgggtaa ctgcattctc cttctaagca aagcaagttc
     1861 tgacacagaa gagatgcttc cgtgtactac ccgattaaag tccatgctgc gacttttgct
     1921 agtgaaaaag ccatcggtcc gttcgctagc attaaagctt ttagcattcc atcttaccag
     1981 tgaagaaggg gctgatacaa agcgtcctct aatagacgcc agagttctct ccagagttac
     2041 tgatttattc attgggaaga aacctattga actcagactg gatgacagaa gagagctggt
     2101 tattaagttg gagactgttg aaaaggtata tgaaatcttc acctcagatg atgttgatct
     2161 cgttttgaga aagtcagctg ctgaacagtt agctgtgatt atgcaagata ttaaaatgca
     2221 tgctgtggtg aaaaagttat gcttaattga caaaataatt gagtatttaa atgaatgtgt
     2281 gagtcaagat ggcaaggttg tagaatgttt ggtacaacca tgcctcacac tcttgaggaa
     2341 ggttttatgt ggtgatccag tcatgcgtgt ttcgctctcg caacagtctt ctcttttgac
     2401 cgtgttattc agagtttcct taatatttca tgaagattgt agtgtcgtga ctgaagttgg
     2461 agcactattt tgtcttctat tatttgatga agtatcgaga atggatatgt ggtctgttaa
     2521 tccttccaat aaaccttctt tgccatcggt cttcagtttg cctgtttccg tttttagaag
     2581 gtaccatcta cctgttcatg taattggaca ccatgctgtg agtccttact ccatagtttt
     2641 gcccttatct gctgattgtt tggccttgaa gccggtgtca gatatgctga gaatagcttg
     2701 gaacctgtca tggtatcatg ggagtgataa tctgttgaag caaatgaact ctgaaactaa
     2761 aacgcaagaa attttagatg cattgaagtt atctacagag gacatcctca ctctgaagat
     2821 aacacacatg gctagtgggc tgcaggactg cctccattcc attgttcagg ctgcaaccca
     2881 cagggaagtt agggctgctg tcaccaggat gagtttttat cttctgaatg acagattgtc
     2941 tttaaagggt tgccctggtc catgtggggt taccttgaag tccttggctt ggcacaccgc
     3001 actaaacagg tttttacagg tgcttcctgc ttgcactgaa gatgagaaac tgctaataga
     3061 tatcatacat tttttaaata aattaataaa ggaacaaaga aaaaattctt cactagaact
     3121 tctaaactgg attctcgaat tacttcttag acatagtgca aacccactgt tagacctctt
     3181 ggttctgaca gagtcacagg cacgagaaga aacagatgat atccggactg ctgtcaggca
     3241 acaacttcag aaagaactga ttgctctttt tgataccttg ctgctcaatt tcatggaagt
     3301 tactgacagg aaatgctcgg aacttcttta cgtttttcaa acgcagctgg ctctgaaact
     3361 gctccagtgt ctgaaagtga cggatgcgcc tcatttctat ggcctgccgt cccttgagcg
     3421 gaccttacga gggatggcta acctcactgc gtttccggga tggagctcac actctcctct
     3481 cacaaagcct ctagatatct gtgtgaagta cttgtcaggt ctccttgagg tcattacttc
     3541 tttttatgtg gagcgtggag gaaatgctat gtccttcatg ggaaaaggtg ttacaaagag
     3601 cacaattctt tgcttgcttc acttatccca tgagatgatg gcccaggctg ggagcttgga
     3661 gtggatgtca ctttggttct tgcctttggg tagtcatagt gaagaacata ttcctactca
     3721 acaaggattg gcttggttga ttccattatg ggttgatcgg gacccagagg tgagattcac
     3781 ttcactggga ttaggatcag cactgaccac ccttgaaacg ggctgtgtgg ccttagcaaa
     3841 cagttgtcag aacatttccg gtgggctctg gggaactgtg gtgaacattc ttctggacca
     3901 gtcagaatgt agtatggtgc gccgggaggc ggcatttatt cttcagaatc tccttgtaat
     3961 tccaatgcct acagaaatta taaaggatta tacttggcag ggtccctgtg ttcatgatga
     4021 ggactctggc ctatcgctca ttggaaaacc tgcccttcag gctcttttat atcactgcca
     4081 tttttatgaa catttgaatc agatggtaaa gcattgttac ctaggacggt gtatgtttga
     4141 tttgaatttt tctgcttttg atagaaattc agaaagcaat gatttaaatg gtttagatga
     4201 ctcattcaag ttttggaggg ctccatctag gacaagtcag gatcgagatc caagttctct
     4261 ctccacctca gaaacaacgg tggcaccttc attggggagt actgaatttc agccacttgt
     4321 gcagtcaaca acacttctac ctgaagcctc ccatgaccag tttgtggctc aaggtcacca
     4381 ggaaagtaca tcaccacggc cacctcatga ttcatctctt tctgctcccc tgcccaaact
     4441 gtgtgttttt gttactccat ctcttctttc agcaatgtgc agcctcttgg acaacctctt
     4501 gacgattgct cccagagaca ctgcaaaggc ttttcgacaa gctcatctca tagaacttct
     4561 ctgtagcatt gcagatgcta ccctcataca gacatgtgtc caggaactca gagccctgct
     4621 gccttcatca cctccagctg aacacactca ggctcaggtt tcctttctcc tggaatacct
     4681 atcctctttg tccaggcttc tgcagtcatg tttattggtg gagcctgacc ttgtgattca
     4741 ggatgagctt gtgaaacctc ttatcaccaa tatcattgga attctcacca tatgtaccaa
     4801 agatgtatta gataaagagt taatatcagc tttttatcac acatggacac atttatttaa
     4861 tcttctggcc atgctcctga ggaaagctgg tgccatcaca ctcccgtttg ttaccgtggc
     4921 cctggccaag cactggacag cggcgattga tatgttctgc acatgtgcag gcttgtctgc
     4981 cacgtgtcct gccctgtata ctgccagctt gcaattcctt tctgttctct tgaccgaaga
     5041 agcaaaaggg catctccagg ctaagagcaa aacacattta tgctgtagtc caacagtggc
     5101 ttcacttctt gatgactctc aggaaaatca gaaatctcta gaacaactta gtgatgtaat
     5161 ccttcagtgc tatgaaggga aatcctccaa agatatcctg aaaagagtag ctgcaaatgc
     5221 attgatgtca ctgctggctg tcagtagaag agcacagaaa catgctttga aagccaatct
     5281 tatagacaat tgcatggagc agatgaaaca cataaatgca caactgaacc tagattctct
     5341 gaggcctggg aaagcagcat tgaaaaaaaa ggaggatggt gttattaaag agttaagcat
     5401 tgccatgcag ctcctaagaa actgtcttta tcaaaatgag gaatgtaaag aagcagctct
     5461 tgaagctcac cttgtccctg tcttgcactc tctctggcct tggattttga tggatgattc
     5521 attgatgcaa atttctctgc agctcctttg tgtctatact gcaaattttc caaatggttg
     5581 cagttctctt tgttggtcaa gttgtggaca acaccctgtt caagctacac atagaggagc
     5641 cgtgagcaac tctctgatgc tgtgtatcct aaagttggct tcccagatgc cactggagaa
     5701 caccacggtt cagcagatgg tttttatgct tctttcaaac ctggccttgt cgcatgactg
     5761 taaaggagta attcagaaga gtaacttctt acagaacttc ctctctctag cattgccaaa
     5821 aggaggaaat aaacatctaa gtaatctgac tattctttgg ttgaagttac tcctgaatat
     5881 atcatctgga gaagatgggc aacaaatgat tctgaggctt gatggctgtc tagacttact
     5941 aacagagatg agcaaataca agcacaagag cagcccttta ttgcctcttc ttatctttca
     6001 taatgtttgc ttcagtcctg caaataaacc caagatcctg gctaatgaaa aagtcattac
     6061 tgtgcttgct gcctgtctgg aaagtgagaa tcaaaatgct cagaggattg gagcagctgc
     6121 cctttgggct ctgatttaca attatcagaa ggcaaaaaca gctttgaaaa gcccatcagt
     6181 aaaaagaaga gtggatgaag catactcctt agcaaagaaa actttcccaa actcagaagc
     6241 aaaccctcta aatgcctatt atttgaaatg tcttgaaaac ctcgtgcagc tccttaattc
     6301 ttcctgagtg ccatgggatg ctacaccttg aagctgacag tcatcaacag gggagctaaa
     6361 gttgaagcca gctgtgtgta gcagctgtta cctgaagacg tgctacctct ctacaaagtg
     6421 ttgatcccct tctttcccat gagagagaga actggtgata ctccaacacc gtccagttgt
     6481 ggcagctctc cagaagtaat agcagctgac aactttctgt gccttttcct ttctgttgaa
     6541 aaggcataga aagttctggg aacataaaca tttttaccct tttctatgcc atttattttg
     6601 taaaaatcct atttaacagt tatttaataa aacaatattt ttagaaacta aaaattgact
     6661 aataattgct gcttacagac ttttatcagt ctcatgaata ttaattttag gagttgaaat
     6721 aagacactgt gtcctggttg tttctctctt tttttaaatt ttaactgatg taaaatttgg
     6781 ctctgtcagt gcaaatcctt attttcaaaa ctttctgtta tccagagcat ccacactgga
     6841 aaagggctat gtagaagtaa gtgtgcatta tttgtaaagg gctgtgtgga agtaaatgta
     6901 catgatttgt aagtagcttt cttaggcaag ttttagtgat gttatcttct tcctagatga
     6961 ctcttaaatc attacatgta taatcttcac cgttgtcttc tgcaaggctg tgtaataaag
     7021 aagaaagaaa tagagttggg gctgtataag cctgggttca aatttagctc agcccaaaac
     7081 atcatgaaga atagagtaag actgaaaaat gcagaagatg gccgggcttg gtggctcatg
     7141 cttatacttt cagctctttg ggagaccgag gtaggtggat cacttgaggc caggagtttg
     7201 agaccagctt gggcaacttg gtgaaatccc atctctccta aaaatacaaa aattagccat
     7261 tcctggtctt gagcgtctat aatctcagct actccagtgg ctgaggcacg agaatctctt
     7321 caacctggga ggcagggagg ttgcagtgag ctgagatcat gccactgcat tccagcgtgg
     7381 gtgacaaagc aagactctgt ctcaaaaaaa aaaaaaaaaa aaaaaaa
//
