LOCUS       XM_006722435            8425 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens rotatin (RTTN), transcript variant X6,
            mRNA.
ACCESSION   XM_006722435
VERSION     XM_006722435.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000018.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006722435.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8425
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
     gene            1..8425
                     /gene="RTTN"
                     /gene_synonym="MSSP"
                     /note="rotatin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 27 ESTs, 242
                     long SRA reads, 1 Protein, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     11 samples with support for all annotated introns"
                     /db_xref="GeneID:25914"
                     /db_xref="HGNC:HGNC:18654"
                     /db_xref="MIM:610436"
     CDS             30..6209
                     /gene="RTTN"
                     /gene_synonym="MSSP"
                     /codon_start=1
                     /product="rotatin isoform X6"
                     /protein_id="XP_006722498.1"
                     /db_xref="GeneID:25914"
                     /db_xref="HGNC:HGNC:18654"
                     /db_xref="MIM:610436"
                     /translation="MVLAGLIRKLGHQLAEIRERALKSILCKIEHNLICYADLIQERQ
                     LFLHLLEWFNFPSVPMKEEVLNLLSRLVKYPPAVQHLVDVGAVEFLSKLRSNVEPNLQ
                     AEIDGILDGLFLLPSEVPALSSASYQTNQTELSKNPEILTGYFPQDKSNFQQMEVPPR
                     PVVNQTVKCLKFSTFPWLPLTTTDRHVLSSNESSLRSSNHTLIWNTCELLKDVIMQDF
                     PAEIFLQRPKIVQSLLSLLKLAFGDGKHRLALQSVSCLQQLCMYLRNRLNFHRDPGFF
                     SNKHDTVSQNSSLSYCHEARGTHHSQNPSPGSSSPRPSVVGRTGQRPRGDGQDWDAAS
                     SSGSSSHAHVNSRISVHSPLDMGHIDLPELETEDTLELQFQQLSLPQFCVSILESAVP
                     LLRTGSRQVIIRVLELLTEDMTLIGEAISTDIWDDSSLFGIDMKEKLLLVLGALGETM
                     CYHKSSISLEQPEVMLVHHRMAFISISLFAVRLLQTLLPVEKASEFLSEPMSTALFLL
                     SLDMPISLEYPNIHEAVVAYLEQLNSENYSIYKRTAEAVYSIECTCNFLSDIGKEGEK
                     NLLELVELADQALRSFSYHQHFPLIKEIISICSKIWKSAQASPLLQGESQKVLLHMLS
                     HPLPRVKAETYHCCLEITKECLGVHNVTKPVSSLCNGIHFLLHPKVLYEISVFGIQEP
                     ESEQVNTAAKAILLYLLQGRLMMTALTWNKFIESLCPVIPILQGYADTEDPLGNCILL
                     LSKASSDTEEMLPCTTRLKSMLRLLLVKKPSVRSLALKLLAFHLTSEEGADTKRPLID
                     ARVLSRVTDLFIGKKPIELRLDDRRELVIKLETVEKVYEIFTSDDVDLVLRKSAAEQL
                     AVIMQDIKMHAVVKKLCLIDKIIEYLNECVSQDGKVVECLVQPCLTLLRKVLCGDPVM
                     RVSLSQQSSLLTVLFRVSLIFHEDCSVVTEVGALFCLLLFDEVSRMDMWSVNPSNKPS
                     LPSVFSLPVSVFRRYHLPVHVIGHHAVSPYSIVLPLSADCLALKPVSDMLRIAWNLSW
                     YHGSDNLLKQMNSETKTQEILDALKLSTEDILTLKITHMASGLQDCLHSIVQAATHRE
                     VRAAVTRMSFYLLNDRLSLKGCPGPCGVTLKSLAWHTALNRFLQVLPACTEDEKLLID
                     IIHFLNKLIKEQRKNSSLELLNWILELLLRHSANPLLDLLVLTESQAREETDDIRTAV
                     RQQLQKELIALFDTLLLNFMEVTDRKCSELLYVFQTQLALKLLQCLKVTDAPHFYGLP
                     SLERTLRGMANLTAFPGWSSHSPLTKPLDICVKYLSGLLEVITSFYVERGGNAMSFMG
                     KGVTKSTILCLLHLSHEMMAQAGSLEWMSLWFLPLGSHSEEHIPTQQGLAWLIPLWVD
                     RDPEVRFTSLGLGSALTTLETGCVALANSCQNISGGLWGTVVNILLDQSECSMVRREA
                     AFILQNLLVIPMPTEIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQM
                     VKHCYLGRCMFDLNFSAFDRNSESNDLNGLDDSFKFWRAPSRTSQDRDPSSLSTSETT
                     VAPSLGSTEFQPLVQSTTLLPEASHDQFVAQGHQESTSPRPPHDSSLSAPLPKLCVFV
                     TPSLLSAMCSLLDNLLTIAPRDTAKAFRQAHLIELLCSIADATLIQTCVQELRALLPS
                     SPPAEHTQAQVSFLLEYLSSLSRLLQSCLLVEPDLVIQDELVKPLITNIIGILTICTK
                     DVLDKELISAFYHTWTHLFNLLAMLLRKAGAITLPFVTVALAKHWTAAIDMFCTCAGL
                     SATCPALYTASLQFLSVLLTEEAKGHLQAKSKTHLCCSPTVASLLDDSQENQKSLEQL
                     SDVILQCYEGKSSKDILKRVAANALMSLLAVSRRAQKHALKANLIDNCMEQMKHINAQ
                     LNLDSLRPGKAALKKKEDGVIKELSIAMQLLRNCLYQNEECKEAALEAHLVPVLHSLW
                     PWILMDDSLMQISLQLLCVYTANFPNGCSSLCWSSCGQHPVQATHRGAVSNSLMLCIL
                     KLASQMPLENTTVQQMVFMLLSNLALSHDCKGVIQKAKINCRS"
ORIGIN      
        1 ctccggcggc tgcagattga cgggacgaga tggtcctggc agggctcatc aggaaactcg
       61 gtcatcagct ggccgagatc agggagcgcg ctctcaagag tattctctgc aagattgagc
      121 acaacttaat ctgctacgct gatctcattc aggagaggca actttttctt catttgctgg
      181 aatggttcaa tttcccgtcc gttccgatga aggaagaggt tctgaacctg ttaagcagat
      241 tggttaagta tcccccagca gtccaacatt tggttgacgt tggtgcagta gagttcttat
      301 ctaagcttcg gtctaatgtg gagccaaatc tgcaggctga aattgatggc attctggatg
      361 gactttttct tcttccttcg gaagttcctg cactatcttc tgcctcatac caaaccaatc
      421 aaactgaatt gtcaaaaaac cctgaaatct taacaggata ttttccccaa gacaaaagta
      481 atttccagca gatggaagtg ccgccacgac cagtggtaaa tcagactgtg aagtgcttga
      541 agttttctac atttccttgg ctacccctga ccaccacaga cagacatgtc ctctcctcta
      601 atgaaagctc tttaagaagt agtaaccaca ctttaatctg gaacacctgt gaactattga
      661 aggatgttat catgcaagat tttcctgctg agattttcct tcaaaggcca aaaattgttc
      721 agagcctttt atctctgttg aaactggcct ttggagatgg aaagcatcgc ctggcattac
      781 agtcggtgtc ctgcctgcag cagctgtgca tgtatttaag aaacagactt aactttcacc
      841 gagatccagg ttttttctcc aataaacacg acacagtttc ccaaaattct tctttgtctt
      901 attgtcatga agcaagaggt actcatcatt cccagaatcc ttccccagga agcagcagcc
      961 ctcggccttc tgtggttggg cgcacaggcc agcgacccag aggagatggc caggactggg
     1021 atgcagcgtc ctctagtgga agtagtagtc atgctcatgt aaactccagg atatccgttc
     1081 attcaccttt ggatatggga cacatagatc tgccagagct ggaaactgaa gacacattgg
     1141 aactacaatt ccagcagctc agtcttcccc agttttgtgt ctccattctg gaatcagctg
     1201 ttcctctctt aagaacaggt agcagacaag tgataataag agttctggaa ttgcttacag
     1261 aggatatgac acttattggt gaagcaattt caacagatat ctgggatgac agcagccttt
     1321 ttggtataga tatgaaggag aaactactcc tggtgttggg agcccttgga gaaaccatgt
     1381 gctaccataa aagtagtatc agtttggagc agccagaggt gatgcttgtg caccacagaa
     1441 tggcctttat cagcatttcc ctgtttgcag ttcgactgct acaaacgctt ctccctgttg
     1501 aaaaggcaag cgagttttta tcagagccta tgtcaacagc attatttctc ctttctttgg
     1561 acatgcctat ttctttggaa tatccaaata ttcatgaagc tgttgtggcc tatttggaac
     1621 agctgaattc tgaaaactac agtatttata aacgaactgc agaggccgtt tattcaattg
     1681 aatgcacctg taacttcctg tctgatattg ggaaagaggg agagaagaat ctcttagaat
     1741 tagtggagct ggcagaccaa gccttgcgta gcttttccta tcatcagcat ttcccgctaa
     1801 taaaggaaat catcagcatt tgttcaaaga tctggaaatc tgctcaggcc agtccattac
     1861 tacaaggaga aagtcagaag gtgcttctcc atatgttgtc tcacccattg ccacgagtga
     1921 aagctgaaac ttaccactgc tgtctggaaa tcacgaagga atgtttaggt gtccataatg
     1981 tcactaaacc cgtgtcttca ctttgcaatg gaattcattt tctacttcat ccaaaagttc
     2041 tgtatgaaat ctctgtattt ggcattcaag agcccgaaag tgagcaggtg aacactgctg
     2101 ccaaggccat tctgttatac ctgcttcagg gacgattgat gatgacagca ttgacctgga
     2161 acaagtttat tgaatctctc tgtcctgtca tcccaatact acagggctat gccgacacag
     2221 aagatcctct gggtaactgc attctccttc taagcaaagc aagttctgac acagaagaga
     2281 tgcttccgtg tactacccga ttaaagtcca tgctgcgact tttgctagtg aaaaagccat
     2341 cggtccgttc gctagcatta aagcttttag cattccatct taccagtgaa gaaggggctg
     2401 atacaaagcg tcctctaata gacgccagag ttctctccag agttactgat ttattcattg
     2461 ggaagaaacc tattgaactc agactggatg acagaagaga gctggttatt aagttggaga
     2521 ctgttgaaaa ggtatatgaa atcttcacct cagatgatgt tgatctcgtt ttgagaaagt
     2581 cagctgctga acagttagct gtgattatgc aagatattaa aatgcatgct gtggtgaaaa
     2641 agttatgctt aattgacaaa ataattgagt atttaaatga atgtgtgagt caagatggca
     2701 aggttgtaga atgtttggta caaccatgcc tcacactctt gaggaaggtt ttatgtggtg
     2761 atccagtcat gcgtgtttcg ctctcgcaac agtcttctct tttgaccgtg ttattcagag
     2821 tttccttaat atttcatgaa gattgtagtg tcgtgactga agttggagca ctattttgtc
     2881 ttctattatt tgatgaagta tcgagaatgg atatgtggtc tgttaatcct tccaataaac
     2941 cttctttgcc atcggtcttc agtttgcctg tttccgtttt tagaaggtac catctacctg
     3001 ttcatgtaat tggacaccat gctgtgagtc cttactccat agttttgccc ttatctgctg
     3061 attgtttggc cttgaagccg gtgtcagata tgctgagaat agcttggaac ctgtcatggt
     3121 atcatgggag tgataatctg ttgaagcaaa tgaactctga aactaaaacg caagaaattt
     3181 tagatgcatt gaagttatct acagaggaca tcctcactct gaagataaca cacatggcta
     3241 gtgggctgca ggactgcctc cattccattg ttcaggctgc aacccacagg gaagttaggg
     3301 ctgctgtcac caggatgagt ttttatcttc tgaatgacag attgtcttta aagggttgcc
     3361 ctggtccatg tggggttacc ttgaagtcct tggcttggca caccgcacta aacaggtttt
     3421 tacaggtgct tcctgcttgc actgaagatg agaaactgct aatagatatc atacattttt
     3481 taaataaatt aataaaggaa caaagaaaaa attcttcact agaacttcta aactggattc
     3541 tcgaattact tcttagacat agtgcaaacc cactgttaga cctcttggtt ctgacagagt
     3601 cacaggcacg agaagaaaca gatgatatcc ggactgctgt caggcaacaa cttcagaaag
     3661 aactgattgc tctttttgat accttgctgc tcaatttcat ggaagttact gacaggaaat
     3721 gctcggaact tctttacgtt tttcaaacgc agctggctct gaaactgctc cagtgtctga
     3781 aagtgacgga tgcgcctcat ttctatggcc tgccgtccct tgagcggacc ttacgaggga
     3841 tggctaacct cactgcgttt ccgggatgga gctcacactc tcctctcaca aagcctctag
     3901 atatctgtgt gaagtacttg tcaggtctcc ttgaggtcat tacttctttt tatgtggagc
     3961 gtggaggaaa tgctatgtcc ttcatgggaa aaggtgttac aaagagcaca attctttgct
     4021 tgcttcactt atcccatgag atgatggccc aggctgggag cttggagtgg atgtcacttt
     4081 ggttcttgcc tttgggtagt catagtgaag aacatattcc tactcaacaa ggattggctt
     4141 ggttgattcc attatgggtt gatcgggacc cagaggtgag attcacttca ctgggattag
     4201 gatcagcact gaccaccctt gaaacgggct gtgtggcctt agcaaacagt tgtcagaaca
     4261 tttccggtgg gctctgggga actgtggtga acattcttct ggaccagtca gaatgtagta
     4321 tggtgcgccg ggaggcggca tttattcttc agaatctcct tgtaattcca atgcctacag
     4381 aaattataaa ggattatact tggcagggtc cctgtgttca tgatgaggac tctggcctat
     4441 cgctcattgg aaaacctgcc cttcaggctc ttttatatca ctgccatttt tatgaacatt
     4501 tgaatcagat ggtaaagcat tgttacctag gacggtgtat gtttgatttg aatttttctg
     4561 cttttgatag aaattcagaa agcaatgatt taaatggttt agatgactca ttcaagtttt
     4621 ggagggctcc atctaggaca agtcaggatc gagatccaag ttctctctcc acctcagaaa
     4681 caacggtggc accttcattg gggagtactg aatttcagcc acttgtgcag tcaacaacac
     4741 ttctacctga agcctcccat gaccagtttg tggctcaagg tcaccaggaa agtacatcac
     4801 cacggccacc tcatgattca tctctttctg ctcccctgcc caaactgtgt gtttttgtta
     4861 ctccatctct tctttcagca atgtgcagcc tcttggacaa cctcttgacg attgctccca
     4921 gagacactgc aaaggctttt cgacaagctc atctcataga acttctctgt agcattgcag
     4981 atgctaccct catacagaca tgtgtccagg aactcagagc cctgctgcct tcatcacctc
     5041 cagctgaaca cactcaggct caggtttcct ttctcctgga atacctatcc tctttgtcca
     5101 ggcttctgca gtcatgttta ttggtggagc ctgaccttgt gattcaggat gagcttgtga
     5161 aacctcttat caccaatatc attggaattc tcaccatatg taccaaagat gtattagata
     5221 aagagttaat atcagctttt tatcacacat ggacacattt atttaatctt ctggccatgc
     5281 tcctgaggaa agctggtgcc atcacactcc cgtttgttac cgtggccctg gccaagcact
     5341 ggacagcggc gattgatatg ttctgcacat gtgcaggctt gtctgccacg tgtcctgccc
     5401 tgtatactgc cagcttgcaa ttcctttctg ttctcttgac cgaagaagca aaagggcatc
     5461 tccaggctaa gagcaaaaca catttatgct gtagtccaac agtggcttca cttcttgatg
     5521 actctcagga aaatcagaaa tctctagaac aacttagtga tgtaatcctt cagtgctatg
     5581 aagggaaatc ctccaaagat atcctgaaaa gagtagctgc aaatgcattg atgtcactgc
     5641 tggctgtcag tagaagagca cagaaacatg ctttgaaagc caatcttata gacaattgca
     5701 tggagcagat gaaacacata aatgcacaac tgaacctaga ttctctgagg cctgggaaag
     5761 cagcattgaa aaaaaaggag gatggtgtta ttaaagagtt aagcattgcc atgcagctcc
     5821 taagaaactg tctttatcaa aatgaggaat gtaaagaagc agctcttgaa gctcaccttg
     5881 tccctgtctt gcactctctc tggccttgga ttttgatgga tgattcattg atgcaaattt
     5941 ctctgcagct cctttgtgtc tatactgcaa attttccaaa tggttgcagt tctctttgtt
     6001 ggtcaagttg tggacaacac cctgttcaag ctacacatag aggagccgtg agcaactctc
     6061 tgatgctgtg tatcctaaag ttggcttccc agatgccact ggagaacacc acggttcagc
     6121 agatggtttt tatgcttctt tcaaacctgg ccttgtcgca tgactgtaaa ggagtaattc
     6181 agaaggccaa gataaattgc agaagttgag agcatttata agaattgagt ctccttttcc
     6241 tctactgttt cttctccctg aactcctcag aagatacttt gttatcacca cataaataga
     6301 aagttcggtc tttctaagga aatggaaaga tcaatcttac caaggaaaga tgttttcagt
     6361 ggcacgttgg agccagcctc ctactgactc atgagtgtca tcttaaattt gcaggaattt
     6421 tataaaaatt ccagttgatg ttacattgtt attttgaaat cagccacagt gggcatatca
     6481 caccacgtaa ttcagcgaac tgtacaaatc ttggatcttt tctaccctca ccacaatcag
     6541 ttgtttattt accagcacat ggctggatat tttcttcatg tatatgttca tgtatgtcat
     6601 atatgtatat atatttgaat atattttctt catatatgta ttcatataca tgcatcactt
     6661 ccaaaatgag acattctctt gaactggata tatgtgatta gcatccataa gaatgagaga
     6721 ttctgcatat gtgagagcag agcgggggca gtgctttcca ccacttcctt atagagcatg
     6781 ttggtgggaa gctaagtggg agcacccaga aggaatgtaa gtgccaatct cgagtctggt
     6841 ctgtgacttt gagctggaga cctattctct ttcagcttca tttgggttta acaaaataat
     6901 ctctaagata tgttcaactc ttaatctgtt attctggtgc tatacttaag aatattttga
     6961 tgaagtgtga tcagactctc tttccaggga cggattaatc aagtcttttt cctctgctct
     7021 aattaggaaa tgcctgagac ttcctctgct gcattaagta ataatgagcc cagacactta
     7081 acacttctac ttcttcatta ctcatctgta ggacatagaa aatgcagcag gtggtattgt
     7141 acaactcagg ctccgaaata tcctgcttgt ttgttttttt ttctaccatg gtatacatct
     7201 ctacatattc tacctggtgt aggaaattgt ctgaaaacat ctttagaagc agcaaaaaaa
     7261 aaaaaaaaaa aaaaaaaaag gagtgcccac agcacattta tatttgagag cactgacatc
     7321 tgctttatca cccttgtcag tcccaaatcc agcaagggtt gaatctaaaa actgtcagtt
     7381 tggctgacag taggtgtgag tgacagcaca tgcagctgaa agtgggcatg taattttaca
     7441 gtttacttat tgtgtgggta atgttgataa tatttctgta gctcatttca ttcttaacac
     7501 tcagagtcct tttgtataaa aacgttaagt ttattttata gattaaagcc aacatcttga
     7561 ttttggtcta ggaaaaccta agagataaac tggagtagat ttaaacagag agagagaaga
     7621 gttattctgt gcaatcataa aagttaagtg attgcatttc atttctaaaa tgtccaccta
     7681 actgtggttt ccatgctgcc atgggctgca gcttgatgca gcacttttat actttgcata
     7741 tagattagtc taagcaataa tttattatct ttcttatagt gaagggtttg gtggggtttt
     7801 ttggaagggg ctttatttgg aggttgaaaa gactcttaca gttcaaataa tagagctttc
     7861 tcatctgtaa gcataataga atgacgtgta gccatcagaa attcttactt gtaatgataa
     7921 gtacctggga taaagtgaat gtaagatgta tctatagatt tgataaaaac aacaacaaca
     7981 cctgtagcta taatgattca aaataccctc actacttcca gagttgttaa ctagtattca
     8041 agactgattt ggatttttgc cttttttcct tccatagggt agcttttaat agcaaaatca
     8101 ccagaaggca gagagaagag aaaactcaag agccctgaaa taatctccaa acttaattac
     8161 caattctaaa taattaagag ttaactatag tatacttcat ccatcatgag gaaataatta
     8221 gcaggaatta aaacttgagc actattttgt tcttcttacc tttttcactt atgcttggaa
     8281 ataatataga tggaatattc agaagctatt agaaaggaga aattaatgta gagggagagt
     8341 atatcagaat gttagttaat tggtcaccaa gggactagga aaataatgaa aaagatgaga
     8401 agaaaataat attctctcta tttat
//
