LOCUS       NM_173821               2296 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens receptor transporter protein 5 (putative) (RTP5),
            mRNA.
ACCESSION   NM_173821 XM_941054
VERSION     NM_173821.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2296)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131097.6 and BC113517.1.
            
            On Nov 23, 2018 this sequence version replaced NM_173821.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090909.1, BC113517.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000343216.3/ ENSP00000345374.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AC131097.6         81827-81831
            6-329               BC113517.1         1-324
            330-330             AC131097.6         83955-83955
            331-1803            BC113517.1         326-1798
            1804-2296           AC131097.6         85429-85921
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q37.3"
     gene            1..2296
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /note="receptor transporter protein 5 (putative)"
                     /db_xref="GeneID:285093"
                     /db_xref="HGNC:HGNC:26585"
     exon            1..186
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1747
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /note="CXXC-type zinc finger protein 11; CXXC finger
                     protein 11; receptor (chemosensory) transporter protein 5
                     (putative); zinc finger, 3CxxC-type 5; 3CxxC-type zinc
                     finger protein 5"
                     /codon_start=1
                     /product="receptor-transporting protein 5"
                     /protein_id="NP_776182.2"
                     /db_xref="CCDS:CCDS42843.1"
                     /db_xref="GeneID:285093"
                     /db_xref="HGNC:HGNC:26585"
                     /translation="MDRAGADMWASTFTLAMAERKPQDVWVLLPEHSLVPGCLDGGGV
                     QYLLVGLSRLQCGHCPGTWDSAHVHVLFHLWWDRASHRGLVKMRIWGQRCRLCPAPGD
                     CQVRPPGEQPFLSRLVLHILQDCYGDGPGPARHPREAYEGCCEACELGVCFLQKAPDP
                     AWSANATKGNFPATAWGGTGTVSRGKPLSTPGDDLGKGGVVIAIPFSLVGTSNDQVPI
                     AEGPAPPAGASLPVTGSCEALVIGQGSIFLSGDSVAMPGGKGFPVAIGDPLFHGPGLL
                     GSSIQTFELKGFLFKGRGSLCSPVGVAQGWGPISLNNGLVPVGKHTPTVFYCVGLSAS
                     GEGSLTFPSSLTSIFTNTLSEPTDGPVATKEASITFPFIFTDVKDAVAEVAEGNGKEG
                     GGQGLVPVGHDALPETNAGGLPSQVKGSLALPFPADVQGKDAFTDITEGKEKEGGLVT
                     AGHDAPLEANAEGPITVSEGCITIPFAVFDVIKRKGGGHVAYGPQGNGCFSQGYYQKR
                     QLRSRFHKARCGCRREEDERPGRACRRPHAEPYEDFWIWVSMTVCVFWLMCMCRLNPG
                     IYPQQV"
     exon            187..2296
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2277..2282
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /note="hexamer: AATAAA"
     polyA_site      2296
                     /gene="RTP5"
                     /gene_synonym="C2orf85; CXXC11; Z3CXXC5"
                     /note="major polyA site"
ORIGIN      
        1 agcccacact gcggagccag gcggcagcat ggaccgggct ggggcagaca tgtgggccag
       61 caccttcacc ctggccatgg ccgagaggaa gccccaggac gtctgggttc tgctacctga
      121 gcacagcctg gtcccgggat gcctggacgg cggtggtgtc cagtacctgc tggtggggct
      181 ctcgaggctc cagtgcggtc actgtccggg gacctgggac tcggcccatg tgcacgtcct
      241 cttccacctg tggtgggaca gggccagcca ccgggggctg gtgaagatgc gcatctgggg
      301 ccagcggtgc aggctgtgcc ccgcacccgg ggactgccag gtgaggcccc cgggcgagca
      361 gcccttcctc agcaggctgg tcttgcacat cctgcaggac tgctacgggg atggccccgg
      421 cccagcccgg caccccaggg aggcctatga gggctgctgt gaggcctgtg agctgggggt
      481 ctgcttcctc cagaaggccc cagaccccgc ctggagcgcc aacgccacaa aaggcaactt
      541 ccccgccacg gcctggggtg gcactggcac cgtctccagg ggcaaaccgc tgtccacccc
      601 tggcgacgac cttggcaagg gtggcgttgt catcgccatc cccttctccc ttgtgggtac
      661 cagcaatgac caggtgccca tcgctgaggg ccctgccccc cctgcggggg cctctctccc
      721 tgtgactggc agctgtgagg ccctggtcat cggccagggc tccatcttcc tgtctgggga
      781 ttcagtggcc atgcctgggg gcaaaggctt cccggtggcc attggagacc ccctcttcca
      841 cggccccggc ctcctcggca gcagcatcca gaccttcgag ctcaagggct tcctcttcaa
      901 aggccggggc tccctctgca gcccggttgg cgtggcccag ggctggggcc ccatctccct
      961 caacaatggc ctcgtccctg tggggaaaca cacgccaacc gtgttctact gtgtgggcct
     1021 ctcggccagc ggggagggct ccctcacctt cccctcctcc ctcaccagca tcttcaccaa
     1081 caccctctcg gagcccaccg atggccctgt ggccactaaa gaggcctcca tcaccttccc
     1141 cttcatcttt actgatgtca aggatgccgt tgctgaggtg gctgaaggca acgggaagga
     1201 aggaggcggc cagggcctcg tcccagtggg tcacgacgcc ctgccagaga ccaatgctgg
     1261 tggcctcccc tcccaggtca agggctccct tgccctcccc ttccctgctg atgtccaagg
     1321 caaagatgcc tttactgaca tcactgaagg caaagagaag gaaggtggcc tggtcaccgc
     1381 gggtcacgac gcccctctgg aggccaatgc cgagggcccc atcacggtta gtgagggctg
     1441 catcaccatc cccttcgcag tcttcgatgt cataaagcgc aagggcggtg gccacgttgc
     1501 ctacggcccc cagggcaatg gctgcttctc ccaaggctat taccagaaga ggcagctgag
     1561 gtccaggttc cacaaggccc gctgtgggtg ccgccgggag gaagacgagc gccctggccg
     1621 tgcctgccgt aggccgcacg ccgagcccta cgaggacttc tggatctggg tgtccatgac
     1681 cgtgtgcgtc ttctggctga tgtgcatgtg tcggctgaac cccgggatct acccgcagca
     1741 agtgtgacgc cccgaagttc aggcaaccct cgcctctggg accccgcctc gcctctgaga
     1801 caccccccaa ccccgccttt gagatgcccg ccccgcctcc gagaccccgc ctccacctcc
     1861 gagacccctt tctctgagac ccccgcctct gaggccccgc cccccgcctc cgagaccccg
     1921 ccctgcctct gagaccccgc ctcacctctg agacaccccc caaccccacc tttgagatgc
     1981 ccgccccgcc tccgtggccc cgcctccacc tccgagaccc cgcctccacc tccgagaccc
     2041 ctttctctga gacccctgcc tctgaagccc cgccccccgc ctccgagacc ccgcttcacc
     2101 tccgaggccc cgccccccgc ctccgagacc ccgccccccg cctccgagac cccgcctcac
     2161 ctctgagacc ccgcccccgc cagcagctca gcccctcctg tctcttgccc ctggttttgt
     2221 gggtctgccc tgagctgtgc ctgtgtgctc cagcctcttc ctatgtgtgt aacttcaata
     2281 aaaccaagca aagcca
//
